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  1. 1.   Rapid and Rigorous IL-17A Production by a Distinct Subpopulation of Effector Memory T Lymphocytes Constitutes a Novel Mechanism of Toxic Shock Syndrome Immunopathology
  2. Szabo, Peter A.; Goswami, Ankur; Mazzuca, Delfina M.; Kim, Kyoungok; O'Gorman, David B.; Hess, David A.; Welch, Ian D.; Young, Howard; Singh, Bhagirath; McCormick, John K.; Haeryfar, S. M. Mansour
  3. JOURNAL OF IMMUNOLOGY. 2017, Apr 1; 198(7): 2805-2818.
  1. 2.   Overexpression of Parkinson's Disease-Associated Mutation LRRK2 G2019S in Mouse Forebrain Induces Behavioral Deficits and a-Synuclein Pathology
  2. Xiong, Yulan; Neifert, Stewart; Karuppagounder, Senthilkumar S; Stankowski, Jeannette N; Lee, Byoung Dae; Grima, Jonathan C; Chen, Guanxing; Ko, Han Seok; Lee, Yunjong; Swing, Debbie; Tessarollo, Lino; Dawson, Ted M; Dawson, Valina L
  3. eNeuro. 2017, Mar-Apr; 4(2):
  1. 3.   Clinical Evaluation of Safety and Immunogenicity of PADRE-Cytomegalovirus (CMV) and Tetanus-CMV Fusion Peptide Vaccines With or Without PF03512676 Adjuvant
  2. La Rosa, C.; Longmate, J.; Lacey, S. F.; Kaltcheva, T.; Sharan, R.; Marsano, D.; Kwon, P.; Drake, J.; Williams, B.; Denison, S.; Broyer, S.; Couture, L.; Nakamura, R.; Kelsey, M. I.; Krieg, A. M.; Diamond, D. J.; Zaia, J. A.
  3. Journal of Infectious Diseases. 2012, Apr; 205(8): 1294-1304.
  1. 4.   Cre-mediated recombination can induce apoptosis in vivo by activating the p53 DNA damage-induced pathway
  2. Zhu, J. J.; Nguyen, M. T.; Nakamura, E.; Yang, J. M.; Mackem, S.
  3. Genesis. 2012, Feb; 50(2): 102-111.
  1. 5.   A Pharmacologic Inhibitor of the Protease Taspase1 Effectively Inhibits Breast and Brain Tumor Growth
  2. Chen, D. Y.; Lee, Y.; Van Tine, B. A.; Searleman, A. C.; Westergard, T. D.; Liu, H.; Tu, H. C.; Takeda, S.; Dong, Y. Y.; Piwnica-Worms, D. R.; Oh, K. J.; Korsmeyer, S. J.; Hermone, A.; Gussio, R.; Shoemaker, R. H.; Cheng, E. H. Y.; Hsieh, J. J. D.
  3. Cancer Research. 2012, Feb; 72(3): 736-746.
  1. 6.   DNA Methyltransferase Inhibitor, Zebularine, Delays Tumor Growth and Induces Apoptosis in a Genetically Engineered Mouse Model of Breast Cancer
  2. Chen, M.; Shabashvili, D.; Nawab, A.; Yang, S. X.; Dyer, L. M.; Brown, K. D.; Hollingshead, M.; Hunter, K. W.; Kaye, F. J.; Hochwald, S. N.; Marquez, V. E.; Steeg, P.; Zajac-Kaye, M.
  3. Molecular Cancer Therapeutics. 2012, Feb; 11(2): 370-382.
  1. 7.   FGF8 is essential for formation of the ductal system in the male reproductive tract
  2. Kitagaki, J.; Ueda, Y.; Chi, X.; Sharma, N.; Elder, C. M.; Truffer, E.; Costantini, F.; Lewandoski, M.; Perantoni, A. O.
  3. Development. 2011, Dec; 138(24): 5369-5378.
  1. 8.   Genetic Inactivation of ERK1 and ERK2 in Chondrocytes Promotes Bone Growth and Enlarges the Spinal Canal
  2. Sebastian, A.; Matsushita, T.; Kawanami, A.; Mackem, S.; Landreth, G. E.; Murakami, S.
  3. Journal of Orthopaedic Research. 2011, Mar; 29(3): 375-379.
  1. 9.   Targeted JAM-C deletion in germ cells by Spo11-controlled Cre recombinase
  2. Pellegrini, M.; Claps, G.; Orlova, V. V.; Barrios, F.; Dolci, S.; Geremia, R.; Rossi, P.; Rossi, G.; Arnold, B.; Chavakis, T.; Feigenbaum, L.; Sharan, S. K.; Nussenzweig, A.
  3. Journal of Cell Science. 2011, Jan; 124(1): 91-99.
  1. 10.   Oncogene-Driven Intrinsic Inflammation Induces Leukocyte Production of Tumor Necrosis Factor That Critically Contributes to Mammary Carcinogenesis
  2. Sangaletti, S.; Tripodo, C.; Ratti, C.; Piconese, S.; Porcasi, R.; Salcedo, R.; Trinchieri, G.; Colombo, M. P.; Chiodoni, C.
  3. Cancer Research. 2010, Oct; 70(20): 7764-7775.
  1. 11.   Altering a Histone H3K4 Methylation Pathway in Glomerular Podocytes Promotes a Chronic Disease Phenotype
  2. Lefevre, G. M.; Patel, S. R.; Kim, D.; Tessarollo, L.; Dressler, G. R.
  3. Plos Genetics. 2010, Oct; 6(10): 15.
  1. 12.   A Dominant-Negative c-jun Mutant Inhibits Lung Carcinogenesis in Mice
  2. Tichelaar, J. W.; Yan, Y.; Tan, Q.; Wang, Y. A.; Estensen, R. D.; Young, M. R.; Colburn, N. H.; Yin, H. L.; Goodin, C.; Anderson, M. W.; You, M.
  3. Cancer Prevention Research. 2010, Sep; 3(9): 1148-1156.
  1. 14.   Mutagenicity of N-ethyl-N-nitrosourea, N-methyl-N-nitrosourea, methyl methanesulfonate and ethyl methanesulfonate in the developing Syrian hamster fetus
  2. Donovan, P.; Smith, G.
  3. Mutation Research-Genetic Toxicology and Environmental Mutagenesis. 2010, Jun; 699(1-2): 55-57.
  1. 15.   Rapamycin Protects Mice from Staphylococcal Enterotoxin B-Induced Toxic Shock and Blocks Cytokine Release In Vitro and In Vivo
  2. Krakauer, T.; Buckley, M.; Issaq, H. J.; Fox, S. D.
  3. Antimicrobial Agents and Chemotherapy. 2010, Mar; 54(3): 1125-1131.
  1. 16.   Accelerating Combination Drug Therapies for Triple Negative Breast Cancer through Comparative Pre-Clinical Testing of Human Xenografts and a Mouse Breast Cancer Model
  2. Bennett, C. N.; Tomlinson, C. C.; Hollingshead, M. G.; Green, J. E.
  3. Cancer Research. 2009, Dec; 69(24): 646S-646S.
  1. 17.   Exercise Effects on Tumorigenesis in a p53-Deficient Mouse Model of Breast Cancer
  2. Colbert, L. H.; Westerlind, K. C.; Perkins, S. N.; Haines, D. C.; Berrigan, D.; Donehower, L. A.; Fuchs-Young, R.; Hursting, S. D.
  3. Medicine and Science in Sports and Exercise. 2009 41(8): 1597-1605.
  1. 18.   Metallothionein protection of cadmium toxicity
  2. Klaassen, C. D.; Liu, J.; Diwan, B. A.
  3. Toxicology and Applied Pharmacology. 2009 238(3): 215-220.
  1. 19.   Upregulation of CD4 Expression during MHC Class II-Specific Positive Selection Is Essential for Error-free Lineage Choice
  2. Sarafova, S. D.; Van Laethem, F.; Adoro, S.; Guinter, T.; Sharrow, S. O.; Feigenbaum, L.; Singer, A.
  3. Immunity. 2009 31(3): 480-490.
  1. 20.   Melanoma Progression Despite Infiltration by In Vivo-primed TRP-2-specific T Cells
  2. Singh, V.; Ji, Q. Y.; Feigenbaum, L.; Leighty, R. M.; Hurwitz, A. A.
  3. Journal of Immunotherapy. 2009 32(2): 129-139.
  1. 21.   The Untapped Potential of Genetically Engineered Mouse Models in Chemoprevention Research: Opportunities and Challenges
  2. Abate-Shen, C.; Brown, P. H.; Colburn, N. H.; Gerner, E. W.; Green, J. E.; Lipkin, M.; Nelson, W. G.; Threadgill, D.
  3. Cancer Prevention Research. 2008 1(3): 161-166.
  1. 22.   Constitutive expression of human keratin 14 gene in mouse lung induces premalignant lesions and squamous differentiation
  2. Dakir, E.; Feigenbaum, L.; Linnoila, R. I.
  3. Carcinogenesis. 2008 29(12): 2377-2384.
  1. 23.   Recombinant Oncolytic Poliovirus Eliminates Glioma In Vivo Without Genetic Adaptation to a Pathogenic Phenotype
  2. Dobrikova, E. Y.; Broadt, T.; Poiley-Nelson, J.; Yang, X. Y.; Soman, G.; Giardina, S.; Harris, R.; Gromeier, M.
  3. Molecular Therapy. 2008 16(11): 1865-1872.
  1. 24.   IKK alpha is required to maintain skin homeostasis and prevent skin cancer
  2. Liu, B. G.; Xia, X. J.; Zhu, F.; Park, E.; Carbajal, S.; Kiguchi, K.; DiGiovanni, J.; Fischer, S. M.; Hu, Y. L.
  3. Cancer Cell. 2008 14(3): 212-225.
  1. 25.   Obesity accelerates mouse mammary tumor growth in the absence of ovarian hormones
  2. Nunez, N. P.; Perkins, S. N.; Smith, N.; Berrigan, D.; Berendes, D. M.; Varticovski, L.; Barrett, J. C.; Hursting, S. D.
  3. Nutrition and Cancer-an International Journal. 2008 60(4): 534-541.
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