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  1. 1.   Distinct uptake and elimination profiles for trastuzumab, human IgG and biocytin-TMR in experimental HER2+ brain metastases of breast cancer
  2. Silvestri, Vanesa L; Tran, Andy D; Chung, Monika; Chung, Natalie; Gril, Brunilde; Robinson,Christina; Difilippantonio,Simone; Wei, Debbie; Kruhlak, Michael J; Peer, Cody J; Figg, W Douglas; Khan, Imran; Steeg, Patricia S
  3. Neuro-Oncology. 2024, Feb 13;
  1. 2.   Trastuzumab Blocks the Receiver Function of HER2 Leading to the Population Shifts of HER2-Containing Homodimers and Heterodimers
  2. Zhao, Jun; Mohan, Nishant; Nussinov, Ruth; Ma, Buyong; Wu, Wen Jin
  3. Antibodies. 2021, Jan 12; 10(1):
  1. 3.   Antibody-drug conjugates for cancer
  2. Chau, Cindy H.; Steeg,Pat; Figg, William D.
  3. Lancet (London, England). 2019, Aug 31; 394(10200): 793-804.
  1. 4.   First-in-human phase 0 study of 111In-CHX-A"-DTPA trastuzumab for HER2 tumor imaging
  2. Kurdziel, K A; Mena, E; McKinney, Y; Wong, K; Adler,Stephen; Sissung, T; Lee, J; Lipkowitz, S; Lindenberg, L; Turkbey, B; Kummar, S; Milenic, D E; Doroshow, J H; Figg, W D; Merino, M J; Paik, C H; Brechbiel, M W; Choyke, P L
  3. Journal of translational science. 2019, Apr; 5(2):
  1. 5.   Complexity in the signaling network: insights from the use of targeted inhibitors in cancer therapy
  2. Logue, J. S.; Morrison, D. K.
  3. Genes & Development. 2012, Apr; 26(7): 641-650.
  1. 6.   Pazopanib Reveals a Role for Tumor Cell B-Raf in the Prevention of HER2(+) Breast Cancer Brain Metastasis
  2. Gril, B.; Palmieri, D.; Qian, Y.; Smart, D.; Ileva, L.; Liewehr, D. J.; Steinberg, S. M.; Steeg, P. S.
  3. Clinical Cancer Research. 2011, Jan; 17(1): 142-153.
  1. 7.   Her-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brain
  2. Palmieri, D.; Bronder, J. L.; Herring, J. M.; Yoneda, T.; Weil, R. J.; Stark, A. M.; Kurek, R.; Vega-Valle, E.; Feigenbaum, L.; Halverson, D.; Vortmeyer, A. O.; Steinberg, S. M.; Aldape, K.; Steeg, P. S.
  3. Cancer Research. 2007, May; 67(9): 4190-4198.
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