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  1. 1.   Degradation of 5hmC-marked stalled replication forks by APE1 causes genomic instability
  2. Kharat,Suhas; Ding, Xia; Swaminathan, Divya; Suresh, Akshey; Singh, Manish; Sengodan,Satheesh; Burkett,Sandra; Marks, Hanna; Pamala, Chinmayi; He,Yafeng; Fox,Stephen; Buehler, Eugen C; Muegge,Kathrin; Martin, Scott E; Sharan,Shyam
  3. Science signaling. 2020, Aug 18; 13(645): pii: eaba8091.
  1. 2.   Comparative clinical and genomic analysis of neurofibromatosis type 2-associated cranial and spinal meningiomas
  2. Pemov, Alexander; Dewan, Ramita; Hansen, Nancy F; Chandrasekharappa, Settara C; Ray-Chaudhury, Abhik; Jones,Kristine; Luo,Wen; Heiss, John D; Mullikin, James C; Chittiboina, Prashant; Stewart, Douglas R; Asthagiri, Ashok R
  3. Scientific reports. 2020, Jul 28; 10(1): 12563.
  1. 3.   The Metabolic Basis of Kidney Cancer
  2. Linehan, W. Marston; Schmidt,Laura; Crooks, Daniel R.; Wei, Darmood; Srinivasan, Ramaprasad; Lang, Martin; Ricketts, Christopher J.
  3. Cancer discovery. 2019, AUG; 9(8): 1006-1021.
  1. 4.   Complexity in the signaling network: insights from the use of targeted inhibitors in cancer therapy
  2. Logue, J. S.; Morrison, D. K.
  3. Genes & Development. 2012, Apr; 26(7): 641-650.
  1. 5.   HECT and RING finger families of E3 ubiquitin ligases at a glance
  2. Metzger, M. B.; Hristova, V. A.; Weissman, A. M.
  3. Journal of Cell Science. 2012, Feb; 125(3): 531-537.
  1. 6.   CHEK2 genomic and proteomic analyses reveal genetic inactivation or endogenous activation across the 60 cell lines of the US National Cancer Institute
  2. Zoppoli, G.; Solier, S.; Reinhold, W. C.; Liu, H.; Connelly, J. W.; Monks, A.; Shoemaker, R. H.; Abaan, O. D.; Davis, S. R.; Meltzer, P. S.; Doroshow, J. H.; Pommier, Y.
  3. Oncogene. 2012, Jan; 31(4): 403-418.
  1. 7.   EZH2 Mediates Epigenetic Silencing of Neuroblastoma Suppressor Genes CASZ1, CLU, RUNX3, and NGFR
  2. Wang, C. X.; Liu, Z. H.; Woo, C. W.; Li, Z. J.; Wang, L. F.; Wei, J. S.; Marquez, V. E.; Bates, S. E.; Jin, Q. H.; Khan, J.; Ge, K.; Thiele, C. J.
  3. Cancer Research. 2012, Jan; 72(1): 315-324.
  1. 8.   Yin Yang 1 positively regulates BRCA1 and inhibits mammary cancer formation
  2. Lee, M. H.; Lahusen, T.; Wang, R. H.; Xiao, C.; Xu, X.; Hwang, Y. S.; He, W. W.; Shi, Y.; Deng, C. X.
  3. Oncogene. 2012, Jan; 31(1): 116-127.
  1. 9.   Structural characterization of inhibitor complexes with checkpoint kinase 2 (Chk2), a drug target for cancer therapy
  2. Lountos, G. T.; Jobson, A. G.; Tropea, J. E.; Self, C. R.; Zhang, G. T.; Pommier, Y.; Shoemaker, R. H.; Waugh, D. S.
  3. Journal of Structural Biology. 2011, Dec; 176(3): 292-301.
  1. 10.   Treatment of breast cancer cells with DNA demethylating agents leads to a release of Pol II stalling at genes with DNA-hypermethylated regions upstream of TSS
  2. Tao, Y. G.; Liu, S.; Briones, V.; Geiman, T. M.; Muegge, K.
  3. Nucleic Acids Research. 2011, Dec; 39(22): 9508-9520.
  1. 11.   Inflammation-induced loss of Pdcd4 is mediated by phosphorylation-dependent degradation
  2. Schmid, T.; Bajer, M. M.; Blees, J. S.; Eifler, L. K.; Milke, L.; Rubsamen, D.; Schulz, K.; Weigert, A.; Baker, A. R.; Colburn, N. H.; Brune, B.
  3. Carcinogenesis. 2011, Oct; 32(10): 1427-1433.
  1. 12.   Gene-specific transcription activation via long-range allosteric shape-shifting
  2. Tsai, C. J.; Nussinov, R.
  3. Biochemical Journal. 2011, Oct; 439: 15-25.
  1. 13.   Von Hippel-Lindau (VHL) Inactivation in Sporadic Clear Cell Renal Cancer: Associations with Germline VHL Polymorphisms and Etiologic Risk Factors
  2. Moore, L. E.; Nickerson, M. L.; Brennan, P.; Toro, J. R.; Jaeger, E.; Rinsky, J.; Han, S. S.; Zaridze, D.; Matveev, V.; Janout, V.; Kollarova, H.; Bencko, V.; Navratilova, M.; Szeszenia-Dabrowska, N.; Mates, D.; Schmidt, L. S.; Lenz, P.; Karami, S.; Linehan, W. M.; Merino, M.; Chanock, S.; Boffetta, P.; Chow, W. H.; Waldman, F. M.; Rothman, N.
  3. Plos Genetics. 2011, Oct; 7(10): 13.
  1. 14.   Actinopolysporins A-C and Tubercidin as a Pdcd4 Stabilizer from the Halophilic Actinomycete Actinopolyspora erythraea YIM 90600
  2. Zhao, L. X.; Huang, S. X.; Tang, S. K.; Jiang, C. L.; Duan, Y. W.; Beutler, J. A.; Henrich, C. J.; McMahon, J. B.; Schmid, T.; Blees, J. S.; Colburn, N. H.; Rajski, S. R.; Shen, B.
  3. Journal of Natural Products. 2011, Sep; 74(9): 1990-1995.
  1. 15.   Dysregulated Delta Np63 alpha Inhibits Expression of Ink4a/arf, Blocks Senescence, and Promotes Malignant Conversion of Keratinocytes
  2. Ha, L. A.; Ponnamperuma, R. M.; Jay, S.; Ricci, M. S.; Weinberg, W. C.
  3. Plos One. 2011, Jul; 6(7): 13.
  1. 16.   Two-tiered Approach Identifies a Network of Cancer and Liver Disease-related Genes Regulated by miR-122
  2. Boutz, D. R.; Collins, P. J.; Suresh, U.; Lu, M. Z.; Ramirez, C. M.; Fernandez-Hernando, C.; Huang, Y. F.; Abreu, R. D.; Le, S. Y.; Shapiro, B. A.; Liu, A. M.; Luk, J. M.; Aldred, S. F.; Trinklein, N. D.; Marcotte, E. M.; Penalva, L. O. F.
  3. Journal of Biological Chemistry. 2011, May; 286(20): 18066-18078.
  1. 17.   Optimization of a Cyclic Peptide Inhibitor of Ser/Thr Phosphatase PPM1D (Wip1)
  2. Hayashi, R.; Tanoue, K.; Durell, S. R.; Chatterjee, D. K.; Jenkins, L. M. M.; Appella, D. H.; Appella, E.
  3. Biochemistry. 2011, May; 50(21): 4537-4549.
  1. 18.   Systematic Proteome Analysis Identifies Transcription Factor YY1 as a Direct Target of miR-34a
  2. Chen, Q. R.; Yu, L. R.; Tsang, P.; Wei, J. S.; Song, Y. K.; Cheuk, A.; Chung, J. Y.; Hewitt, S. M.; Veenstra, T. D.; Khan, J.
  3. Journal of Proteome Research. 2011, Feb; 10(2): 479-487.
  1. 19.   Carminomycin I Is an Apoptosis Inducer That Targets the Golgi Complex in Clear Cell Renal Carcinoma Cells
  2. Woldemichael, G. M.; Turbyville, T. J.; Linehan, W. M.; McMahon, J. B.
  3. Cancer Research. 2011, Jan; 71(1): 134-142.
  1. 20.   Constitutive reductions in mTOR alter cell size, immune cell development, and antibody production
  2. Zhang, S. L.; Readinger, J. A.; DuBois, W.; Janka-Junttila, M.; Robinson, R.; Pruitt, M.; Bliskovsky, V.; Wu, J. Z.; Sakakibara, K.; Patel, J.; Parent, C. A.; Tessarollo, L.; Schwartzberg, P. L.; Mock, B. A.
  3. Blood. 2011, Jan; 117(4): 1228-1238.
  1. 21.   Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma-prone families with and without CDKN2A mutations
  2. Yang, X. R.; Liang, X. Y.; Pfeiffer, R. M.; Wheeler, W.; Maeder, D.; Burdette, L.; Yeager, M.; Chanock, S.; Tucker, M. A.; Goldstein, A. M.
  3. Familial Cancer. 2010, Dec; 9(4): 625-633.
  1. 22.   Neuralized1 causes apoptosis and downregulates Notch target genes in medulloblastoma
  2. Teider, N.; Scott, D. K.; Neiss, A.; Weeraratne, S. D.; Amani, V. M.; Wang, Y. F.; Marquez, V. E.; Cho, Y. J.; Pomeroy, S. L.
  3. Neuro-Oncology. 2010, Dec; 12(12): 1244-+.
  1. 23.   TNF/p38 alpha/Polycomb Signaling to Pax7 Locus in Satellite Cells Links Inflammation to the Epigenetic Control of Muscle Regeneration
  2. Palacios, D.; Mozzetta, C.; Consalvi, S.; Caretti, G.; Saccone, V.; Proserpio, V.; Marquez, V. E.; Valente, S.; Mai, A.; Forcales, S. V.; Sartorelli, V.; Puri, P. L.
  3. Cell Stem Cell. 2010, Oct; 7(4): 455-469.
  1. 24.   Conformational ensembles, signal transduction and residue hot spots: Application to drug discovery
  2. Ozbabacan, S. E. A.; Gursoy, A.; Keskin, O.; Nussinov, R.
  3. Current Opinion in Drug Discovery & Development. 2010, Sep; 13(5): 527-537.
  1. 25.   CCAAT/enhancer binding protein delta (C/EBP delta, CEBPD)-mediated nuclear import of FANCD2 by IPO4 augments cellular response to DNA damage
  2. Wang, J.; Sarkar, T. R.; Zhou, M.; Sharan, S.; Ritt, D. A.; Veenstra, T. D.; Morrison, D. K.; Huang, A. M.; Sterneck, E.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2010, Sep; 107(37): 16131-16136.
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