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  1. 1.   Using PET imaging to track STING-induced interferon signaling
  2. Bafor,Enitome; Young,Howard
  3. Proceedings of the National Academy of Sciences of the United States of America. 2021, Sep 21; 118(38):
  1. 2.   Induction of Kaposi Sarcoma Associated Herpesvirus-encoded Thymidine Kinase (ORF21) by X-Box Binding Protein-1
  2. Wang, Victoria; Davis, David A; Deleage,Claire; Brands,Catherine; Choi, Hong S; Haque, Muzammel; Yarchoan, Robert
  3. Journal of virology. 2020, MAR; 94(5):
  1. 3.   Effect of North Bicyclo[3.1.0]hexane 2 '-Deoxy-pseudosugars on RNA Interference: A Novel Class of siRNA Modification
  2. Terrazas, M.; Ocampo, S. M.; Perales, J. C.; Marquez, V. E.; Eritja, R.
  3. Chembiochem. 2011, May; 12(7): 1056-1065.
  1. 4.   Phenotypic characterization of drug resistance-associated mutations in HIV-1 RT connection and RNase H domains and their correlation with thymidine analogue mutations
  2. Lengruber, R. B.; Delviks-Frankenberry, K. A.; Nikolenko, G. N.; Baumann, J.; Santos, A. F.; Pathak, V. K.; Soares, M. A.
  3. Journal of Antimicrobial Chemotherapy. 2011, Apr; 66(4): 702-708.
  1. 5.   Structural basis of HIV-1 resistance to AZT by excision
  2. Tu, X. Y.; Das, K.; Han, Q. W.; Bauman, J. D.; Clark, A. D.; Hou, X. R.; Frenkel, Y. V.; Gaffney, B. L.; Jones, R. A.; Boyer, P. L.; Hughes, S. H.; Sarafianos, S. G.; Arnold, E.
  3. Nature Structural & Molecular Biology. 2010, Oct; 17(10): 1202-+.
  1. 6.   The Nucleoside Analogue D-carba T Blocks HIV-1 Reverse Transcription
  2. Boyer, P. L.; Vu, B. C.; Ambrose, Z.; Julias, J. G.; Warnecke, S.; Liao, C. Z.; Meier, C.; Marquez, V. E.; Hughes, S. H.
  3. Journal of Medicinal Chemistry. 2009 52(17): 5356-5364.
  1. 7.   Structural Basis for the Role of the K65R Mutation in HIV-1 Reverse Transcriptase Polymerization, Excision Antagonism, and Tenofovir Resistance
  2. Das, K.; Bandwar, R. P.; White, K. L.; Feng, J. Y.; Sarafianos, S. G.; Tuske, S.; Tu, X. Y.; Clark, A. D.; Boyer, P. L.; Hou, X. R.; Gaffney, B. L.; Jones, R. A.; Miller, M. D.; Hughes, S. H.; Arnold, E.
  3. Journal of Biological Chemistry. 2009 284(50): 35092-35100.
  1. 8.   D-(+)-iso-methanocarbathymidine: A high-affinity substrate for herpes simplex virus 1 thymidine kinase
  2. Comin, M. J.; Vu, B. C.; Boyer, P. L.; Liao, C.; Hughes, S. H.; Marquez, V. E.
  3. Chemmedchem. 2008 3(7): 1129-1134.
  1. 9.   Acyclovir is activated into a HIV-1 reverse transcriptase inhibitor in herpesvirus-infected human tissues
  2. Lisco, A.; Vanpouille, C.; Tchesnokov, E. P.; Grivel, J. C.; Biancotto, A.; Brichacek, B.; Elliott, J.; Fromentin, E.; Shattock, R.; Anton, P.; Gorelick, R.; Balzarini, J.; McGuigan, C.; Derudas, M.; Gotte, M.; Schinazi, R. F.; Margolis, L.
  3. Cell Host & Microbe. 2008 4(3): 260-270.
  1. 10.   Rational strain selection and engineering creates a broad-spectrum, systemically effective oncolytic poxvirus, JX-963
  2. Thorne, S. H.; Hwang, T. H. H.; O'Gorman, W. E.; Bartlett, D. L.; Sei, S.; Kanji, F.; Brown, C.; Werier, J.; Cho, J. H.; Lee, D. E.; Wang, Y.; Bell, J.; Kirn, D. H.
  3. Journal of Clinical Investigation. 2007, Nov; 117(11): 3350-3358.
  1. 11.   Mutations in the connection domain of HIV-1 reverse transcriptase increase 3 '-azido-3 '-deoxythymidine resistance
  2. Nikolenko, G. N.; Delviks-Frankenberry, K. A.; Palmer, S.; Maldarelli, F.; Fivash, M. J.; Coffin, J. M.; Pathak, V. K.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2007, Jan; 104(1): 317-322.
  1. 12.   The history of N-methanocarbathymidine: The investigation of a conformational concept leads to the discovery of a potent and selective nucleoside antiviral agent
  2. Marquez, V. E.; Hughes, S. H.; Sei, S.; Agbaria, R.
  3. Antiviral Research. 2006, Sep; 71(2-3): 268-275.
  1. 13.   Nucleotide excision repair and template-independent addition by HIV-1 reverse transcriptase in the presence of nucleocapsid protein
  2. Bampi, C.; Bibillo, A.; Wendeler, M.; Divita, G.; Gorelick, R. J.; Le Grice, S. F. J.; Darlix, J. L.
  3. Journal of Biological Chemistry. 2006, Apr; 281(17): 11736-11743.
  1. 14.   Synthesis of bicyclo 3.1.0 hexanes functionalized at the tip of the cyclopropane ring. Application to the synthesis of carbocyclic nucleosides
  2. Comin, M. J.; Parrish, D. A.; Deschamps, J. R.; Marquez, V. E.
  3. Organic Letters. 2006, Feb; 8(4): 705-708.
  1. 15.   Potent antiviral activity of North-methanocarbathymidine against Kaposi's sarcoma-associated herpesvirus
  2. Zhu, W. M.; Burnette, A.; Dorjsuren, D.; Roberts, P. E.; Huleihel, M.; Shoemaker, R. H.; Marquez, V. E.; Agbaria, R.; Sei, S.
  3. Antimicrobial Agents and Chemotherapy. 2005, DEC; 49(12): 4965-4973.
  1. 16.   Understanding how the herpes thymidine kinase orchestrates optimal sugar and nucleobase conformations to accommodate its substrate at the active site: A chemical approach
  2. Marquez, V. E.; Choi, Y.; Comin, M. J.; Russ, P.; George, C.; Huleihel, M.; Ben-Kasus, T.; Agbaria, R.
  3. Journal of the American Chemical Society. 2005, NOV 2; 127(43): 15145-15150.
  1. 17.   Metabolic activation of zebularine, a novel DNA methylation inhibitor, in human bladder carcinoma cells
  2. Ben-Kasus, T.; Ben-Zvi, Z.; Marquez, V. E.; Kelley, J. A.; Agbaria, R.
  3. Biochemical Pharmacology. 2005, JUL 1; 70(1): 121-133.
  1. 18.   Azidothymidine inhibits NF-kappa B and induces Epstein-Barr virus gene expression in Burkitt lymphoma
  2. Kurokawa, M.; Ghosh, S. K.; Ramos, J. C.; Mian, A. M.; Toomey, N. L.; Cabral, L.; Whitby, D.; Barber, G. N.; Dittmer, D. P.; Harrington, W. J.
  3. Blood. 2005, JUL 1; 106(1): 235-240.
  1. 19.   Dynamics of the antiviral activity of N-methanocarbathymidine against herpes simplex virus type 1 in cell culture
  2. Huleihel, M.; Talishanisky, M.; Ford, H.; Marquez, V. E.; Kelley, J. A.; Johns, D. G.; Agbaria, R.
  3. International Journal of Antimicrobial Agents. 2005, MAY; 25(5): 427-432.
  1. 20.   Mechanism for nucleoside analog-mediated abrogation of HIV-1 replication: Balance between RNase H activity and nucleotide excision
  2. Nikolenko, G. N.; Palmer, S.; Maldarelli, F.; Mellors, J. W.; Coffin, J. M.; Pathak, V. K.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2005, FEB 8; 102(6): 2093-2098.
  1. 21.   Engineering DNA topology with locked nucleosides: A structural study
  2. Maderia, M.; Wu, J.; Bax, A.; Shenoy, S.; O'Keefe, B.; Marquez, V. E.; Barchi, J. J.
  3. Nucleosides Nucleotides & Nucleic Acids. 2005 24(5-7, Sp. Iss.): 687-690.
  1. 22.   A 4 '-C-ethynyl-2 ',3 '-dideoxynucleoside analogue highlights the role of the 3 '-OH in anti-HIV active 4 '-C-ethynyl-2 '-deoxy nucleosides
  2. Siddiqui, M. A.; Hughes, S. H.; Boyer, P. L.; Mitsuya, H.; Van, Q. N.; George, C.; Sarafinanos, S. G.; Marquez, V. E.
  3. Journal of Medicinal Chemistry. 2004, OCT 7; 47(21): 5041-5048.
  1. 23.   Effects of the Delta 67 complex of mutations in human immunodeficiency virus type 1 reverse transcriptase on nucleoside analog excision
  2. Boyer, P. L.; Imamichi, T.; Sarafianos, S. G.; Arnold, E.; Hughes, S. H.
  3. Journal of Virology. 2004, SEP; 78(18): 9987-9997.
  1. 24.   Experimental and structural evidence that herpes 1 kinase and cellular DNA polymerase(s) discriminate on the basis of sugar pucker
  2. Marquez, V. E.; Ben Kasus, T.; Barchi, J. J.; Green, K. M.; Nicklaus, M. C.; Agbaria, R.
  3. Journal of the American Chemical Society. 2004 126(2): 543-549.
  1. 25.   Conceptual "heat-driven" approach to the synthesis of DNA oligonucleotides on microarrays
  2. Grajkowski, A.; Cieslak, J.; Chmielewski, M. K.; Marchan, V.; Phillips, L. R.; Wilk, A.; Beaucage, S. L.
  3. THERAPEUTIC OLIGONUCLEOTIDES. 2003; 1002 : 1-11.
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