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  1. 1.   Toward a CRISPR-based mouse model of Vhl-deficient clear cell kidney cancer: Initial experience and lessons learned
  2. Stransky, Laura A; Gao, Wenhua; Schmidt,Laura; Bi, Kevin; Ricketts, Christopher J; Ramesh, Vijyendra; James,Amy; Difilippantonio,Simone; Ileva,Lilia; Kalen,Joseph; Karim,Baktiar; Jeon, Albert; Morgan,Tamara; Warner,Andrew; Turan, Sevilay; Unite,Joanne; Tran,Bao; Choudhari,Sulbha; Zhao,Yongmei; Linn, Douglas E; Yun, Changhong; Dhandapani, Sripriya; Parab, Vaishali; Pinheiro, Elaine M; Morris,Nicole; He, Lixia; Vigeant, Sean M; Pignon, Jean-Christophe; Sticco-Ivins, Maura; Signoretti, Sabina; Van Allen, Eliezer M; Linehan, W Marston; Kaelin, William G
  3. Proceedings of the National Academy of Sciences of the United States of America. 2024, Oct 08; 121(41): e2408549121.
  1. 2.   Dromedary camel nanobodies broadly neutralize SARS-CoV-2 variants
  2. Hong, Jessica; Kwon, Hyung Joon; Cachau,Raul; Chen, Catherine Z; Butay, Kevin John; Duan, Zhijian; Li, Dan; Ren, Hua; Liang, Tianyuzhou; Zhu,Jianghai; Dandey, Venkata P; Martin, Negin P; Esposito,Dom; Ortega-Rodriguez, Uriel; Xu, Miao; Borgnia, Mario J; Xie, Hang; Ho, Mitchell
  3. Proceedings of the National Academy of Sciences of the United States of America. 2022, May 03; 119(18): e2201433119.
  1. 3.   Comprehensive characterization of Alu-mediated breakpoints in germline VHL gene deletions and rearrangements in patients from 71 VHL families
  2. Vocke, Cathy D.; Ricketts, Christopher J.; Schmidt,Laura; Ball, Mark W.; Middelton, Lindsay A.; Zbar, Berton; Linehan, W. Marston
  3. Human Mutation. 2021, Mar 06; 42(5): 520-529.
  1. 4.   A Forgotten Episode of Marburg Virus Disease: Belgrade, Yugoslavia, 1967
  2. Ristanovic, Elizabeta S.; Kokoskov, Nenad S.; Crozier,Ian; Kuhn, Jens H.; Gligic, Ana S.
  3. Microbiology and molecular biology reviews : MMBR. 2020, Jun; 84(2):
  1. 5.   Distinct genome-wide methylation patterns in sporadic and hereditary nonfunctioning pancreatic neuroendocrine tumors
  2. Tirosh, Amit; Mukherjee, Sanjit; Lack, Justin; Gara, Sudheer Kumar; Wang, Sophie; Quezado, Martha M; Keutgen, Xavier M; Wu, Xiaolin; Cam, Maggie; Kumar, Suresh; Patel, Dhaval; Nilubol, Naris; Tyagi, Monica Varun; Kebebew, Electron
  3. Cancer. 2019, Apr 15; 125(8): 1247-1257.
  1. 6.   Allogeneic Hematopoietic Stem-Cell Transplantation for GATA2 Deficiency Using a Busulfan-Based Regimen
  2. Parta, Mark; Shah, Nirali N; Baird, Kristin; Rafei, Hind; Calvo, Katherine R; Hughes, Thomas; Cole, Kristen; Kenyon, Meg; Blacklock Schuver, Bazetta; Cuellar-Rodriguez, Jennifer; Zerbe, Christa S; Holland, Steven M; Hickstein, Dennis D
  3. Biology of Blood and Marrow Transplantation. 2018, Jun; 24(6): 1250-1259.
  1. 7.   Inactivation of the von Hippel-Lindau tumor suppressor leads to selective expression of a human endogenous retrovirus in kidney cancer
  2. Cherkasova, E.; Malinzak, E.; Rao, S.; Takahashi, Y.; Senchenko, V. N.; Kudryavtseva, A. V.; Nickerson, M. L.; Merino, M.; Hong, J. A.; Schrump, D. S.; Srinivasan, R.; Linehan, W. M.; Tian, X.; Lerman, M. I.; Childs, R. W.
  3. Oncogene. 2011, Nov; 30(47): 4697-4706.
  1. 8.   Molecular Diagnosis and Therapy of Kidney Cancer
  2. Linehan, W. M.; Bratslavsky, G.; Pinto, P. A.; Schmidt, L. S.; Neckers, L.; Bottaro, D. P.; Srinivasan, R.
  3. Annual Review of Medicine. 2010, Feb; 61: 329-343.
  1. 9.   Loss of PL6 protein expression in renal clear cell carcinomas and other VHL-deficient tumours
  2. Ivanova, A. V.; Vortmeyer, A.; Ivanov, S. V.; Nickerson, M. L.; Maher, E. R.; Lerman, M. I.
  3. Journal of Pathology. 2008 214(1): 46-57.
  1. 10.   Improved identification of von Hippel-Lindau gene alterations in clear cell renal tumors
  2. Nickerson, M. L.; Jaeger, E.; Shi, Y.; Durocher, J. A.; Mahurkar, S.; Zaridze, D.; Matveev, V.; Janout, V.; Kollarova, H.; Bencko, V.; Navratilova, M.; Szeszenia-Dabrowska, N.; Mates, D.; Mukeria, A.; Holcatova, I.; Schmidt, L. S.; Toro, J. R.
  3. Clinical Cancer Research. 2008 14(15): 4726-4734.
  1. 11.   Differential effects of donor T-cell cytokines on outcome with continuous bortezomib administration after allogeneic bone marrow transplantation
  2. Sun, K.; Li, M. H.; Sayers, T. J.; Welniak, L. A.; Murphy, W. J.
  3. Blood. 2008 112(4): 1522-1529.
  1. 12.   EF24, a novel curcumin analog, disrupts the microtubule cytoskeleton and inhibits HIF-1
  2. Thomas, S. L.; Zhong, D. S.; Zhou, W.; Malik, S.; Liotta, D.; Snyder, J. P.; Hamel, E.; Giannakakou, P.
  3. Cell Cycle. 2008 7(15): 2409-2417.
  1. 13.   Expression of hypoxia-inducible factor 1 alpha, hypoxia-inducible factor 2 alpha, and von Hippel-Lindau protein in epitheLiaL ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1 alpha is an independent prognostic factor in ovarian carcinoma
  2. Osada, R.; Horiuchi, A.; Kikuchi, N.; Yoshida, J.; Hayashi, A.; Ota, M.; Katsuyama, Y.; Melilo, G.; Konishi, I.
  3. Human Pathology. 2007, Sep; 38(9): 1310-1320.
  1. 14.   Comprehensive analysis of co-occurring domain sets in yeast proteins
  2. Cohen-Gihon, I.; Nussinov, R.; Sharan, R.
  3. Bmc Genomics. 2007, Jun; 8
  1. 15.   Hypoxic repression of STAT1 and its downstream genes by a pVHL/HIF-1 target DEC1/STRA13
  2. Ivanov, S. V.; Salnikow, K.; Ivanova, A. V.; Bai, L.; Lerman, M. I.
  3. Oncogene. 2007, Feb; 26(6): 802-812.
  1. 16.   Structural basis for inhibition of translation by the tumor suppressor Pdcd4
  2. LaRonde-LeBlanc, N.; Santhanam, A. N.; Baker, A. R.; Wlodawer, A.; Colburn, N. H.
  3. Molecular and Cellular Biology. 2007, Jan; 27(1): 147-156.
  1. 17.   Development of a cell-based reporter assay for screening of inhibitors of hypoxia-inducible factor 2-induced gene expression
  2. Woldemichael, G. M.; Vasselli, J. R.; Gardella, R. S.; McKee, T. C.; Linehan, W. M.; McMahon, J. B.
  3. Journal of Biomolecular Screening. 2006, Sep; 11(6): 678-687.
  1. 18.   Vascular defects and liver damage by the acute inactivation of the VHL gene during mouse embryogenesis
  2. Hong, S. B.; Furihata, M.; Baba, M.; Zbar, B.; Schmidt, L. S.
  3. Laboratory Investigation. 2006, Jul; 86(7): 664-675.
  1. 19.   Peyer patches are not required for acute graft-versus-host disease after myeloablative conditioning and murine allogeneic bone marrow transplantation
  2. Welniak, L. A.; Kuprash, D. V.; Tumanov, A. V.; Panoskaltsis-Mortari, A.; Blazar, B. R.; Sun, K.; Nedospasov, S. A.; Murphy, W. J.
  3. Blood. 2006, JAN 1; 107(1): 410-412.
  1. 20.   Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): delayed administration of bortezomib results in increased GVHD-dependent gastrointestinal toxicity
  2. Sun, K.; Wilkins, D. E. C.; Anver, M. R.; Sayers, T. J.; Panoskaltsis-Mortari, A.; Blazar, B. R.; Weiniak, L. A.; Murphy, W. J.
  3. Blood. 2005, NOV 1; 106(9): 3293-3299.
  1. 21.   Triptolide, a constituent of immunosuppressive Chinese herbal medicine, is a potent suppressor of dendritic-cell maturation and trafficking
  2. Chen, X.; Murakami, T.; Oppenheim, J. J.; Howard, O. M. Z.
  3. Blood. 2005, OCT 1; 106(7): 2409-2416.
  1. 22.   Topotecan blocks hypoxia-inducible factor-1 alpha, and vascular endothelial growth factor expression induced by insulin-like growth factor-I in neuroblastoma cells
  2. Beppu, Y.; Nakamura, K.; Linehan, W. M.; Rapisarda, A.; Thiele, C. J.
  3. Cancer Research. 2005, JUN 1; 65(11): 4775-4781.
  1. 23.   Genetic basis of cancer of the kidney: Disease specific approaches to therapy
  2. Linehan, W. M.; Vasselli, J.; Srinivasan, R.; Walther, M. M.; Merino, M.; Choyke, P.; Vocke, C.; Schmidt, L.; Isaacs, J. S.; Glenn, G.; Toro, J.; Zbar, B.; Bottaro, D.; Neckers, L.
  3. Clinical Cancer Research. 2004, SEP 15; 10(18, Part 2 Suppl. S): 6282S-6289S.
  1. 24.   Solid renal tumor severity in von Hippel Lindau disease is related to germline deletion length and location
  2. Maranchie, J. K.; Afonso, A.; Albert, P. S.; Kalyandrug, S.; Phillips, J. L.; Zhou, S.; Peterson, J.; Ghadimi, B. M.; Hurley, K.; Riss, J.; Vasselli, J. R.; Ried, T.; Zbar, B.; Choyke, P.; Walther, M. M.; Klausner, R. D.; Linehan, W. M.
  3. Human Mutation. 2004 23(1): 40-46.
  1. 25.   The absence of Peyer's patches or host TNF-alpha does not affect GVHD progression in an allogeneic BMT model using extensive conditioning regimens
  2. Welniak, L. A.; Kuprash, D. V.; Tumanov, A. V.; Sun, K.; Stull, S. W.; Anver, M. R.; Nedospasov, S. A.; Murphy, W. J.
  3. Biology of Blood and Marrow Transplantation. 2004 10(2, Suppl. 1): 52-52.
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