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  1. 1.   Molecular Dynamics Approaches Estimate the Binding Energy of HIV-1 Integrase Inhibitors and Correlate with In Vitro Activity
  2. Johnson, B. C.; Metifiot, M.; Pommier, Y.; Hughes, S. H.
  3. Antimicrobial Agents and Chemotherapy. 2012, Jan; 56(1): 411-419.
  1. 2.   Localization of ASV Integrase-DNA Contacts by Site-Directed Crosslinking and their Structural Analysis
  2. Peletskaya, E.; Andrake, M.; Gustchina, A.; Merkel, G.; Alexandratos, J.; Zhou, D. W.; Bojja, R. S.; Satoh, T.; Potapov, M.; Kogon, A.; Potapov, V.; Wlodawer, A.; Skalka, A. M.
  3. Plos One. 2011, Dec; 6(12):
  1. 3.   Tautomerism and Magnesium Chelation of HIV-1 Integrase Inhibitors: A Theoretical Study
  2. Liao, C. Z.; Nicklaus, M. C.
  3. Chemmedchem. 2010, Jul 5; 5(7): 1053-1066.
  1. 4.   HIV-1 Integrase and Virus and Cell DNAs: Complex Formation and Perturbation by Inhibitors of Integration
  2. Hobaika, Z.; Zargarian, L.; Maroun, R. G.; Mauffret, O.; Burke, T. R.; Ferm, jian
  3. Neurochemical Research. 2010, Jun; 35(6): 888-893.
  1. 5.   An Allosteric Mechanism for Inhibiting HIV-1 Integrase with a Small Molecule
  2. Kessl, J. J.; Eidahl, J. O.; Shkriabai, N.; Zhao, Z. J.; Mckee, C. J.; Hess, S.; Burke, T. R.; Kvaratskhelia, M.
  3. Molecular Pharmacology. 2009 76(4): 824-832.
  1. 6.   Vif is a RNA chaperone that could temporally regulate RNA dimerization and the early steps of HIV-1 reverse transcription
  2. Henriet, S.; Sinck, L.; Bec, G.; Gorelick, R. J.; Marquet, R.; Paillart, J. C.
  3. Nucleic Acids Research. 2007, Aug; 35(15): 5141-5153.
  1. 7.   Human immunodeficiency virus type 1 cDNAs produced in the presence of APOBEC3G exhibit defects in plus-strand DNA transfer and integration
  2. Mbisa, J. L.; Barr, R.; Thomas, J. A.; Vandegraaff, N.; Dorweiler, I. J.; Svarovskaia, E. S.; Brown, W. L.; Mansky, L. M.; Gorelick, R. J.; Harris, R. S.; Engelman, A.; Pathak, V. K.
  3. Journal of Virology. 2007, Jul; 81(13): 7099-7110.
  1. 8.   Capsid is an important determinant for functional complementation of murine leukemia virus and spleen necrosis virus Gag proteins
  2. Lee, S. K.; Boyko, V.; Hu, W. S.
  3. Virology. 2007, Apr; 360(2): 388-397.
  1. 9.   Probing HIV-1 integrase inhibitor binding sites with position-specific integrase-DNA cross-linking assays
  2. Johnson, A. A.; March, C.; Patil, S. S.; Costi, R.; Di Santo, R.; Burke, T. R.; Pommier, Y.
  3. Molecular Pharmacology. 2007, Mar; 71(3): 893-901.
  1. 10.   Characterization of human immunodeficiency virus type 1 (HIV-1) containing mutations in the nucleocapsid protein at a putative HIV-1 protease cleavage site
  2. Thomas, J. A.; Shulenin, S.; Coren, L. V.; Bosche, W. J.; Gagliardi, T. D.; Gorelick, R. J.; Oroszlan, S.
  3. Virology. 2006, Oct; 354(2): 261-270.
  1. 11.   Human immunodeficiency virus type 1 nucleocapsid zinc-finger mutations cause defects in reverse transcription and integration
  2. Thomas, J. A.; Gagliardi, T. D.; Alvord, W. G.; Lubomirski, M.; Bosche, W. J.; Gorelick, R. J.
  3. Virology. 2006, Sep; 353(1): 41-51.
  1. 12.   Nucleotide excision repair and template-independent addition by HIV-1 reverse transcriptase in the presence of nucleocapsid protein
  2. Bampi, C.; Bibillo, A.; Wendeler, M.; Divita, G.; Gorelick, R. J.; Le Grice, S. F. J.; Darlix, J. L.
  3. Journal of Biological Chemistry. 2006, Apr; 281(17): 11736-11743.
  1. 13.   Chemical library screen for novel inhibitors of Kaposi's sarcoma-associated herpesvirus processive DNA synthesis
  2. Dorjsuren, D.; Burnette, A.; Gray, G. N.; Chen, X. L.; Zhu, W. M.; Roberts, P. E.; Currens, M. J.; Shoemaker, R. H.; Ricciardi, R. P.; Sei, S.
  3. Antiviral Research. 2006, JAN; 69(1): 9-23.
  1. 14.   Mutations in the U5 sequences adjacent to the primer binding site do not affect tRNA cleavage by Rous sarcoma virus RNase H but do cause aberrant integrations in vivo
  2. Oh, J.; Chang, K. W.; Hughes, S. H.
  3. Journal of Virology. 2006, JAN; 80(1): 451-459.
  1. 15.   Alternate polypurine tracts (PPTs) affect the Rous sarcoma virus RNase H cleavage specificity and reveal a preferential cleavage following a GA dinucleotide sequence at the PPT-U3 junction
  2. Chang, K. W.; Julias, J. G.; Alvord, W. G.; Oh, J.; Hughes, S. H.
  3. Journal of Virology. 2005, NOV; 79(21): 13694-13704.
  1. 16.   Structural determinants of HIV-1 nucleocapsid protein for cTAR DNA binding and destabilization, and correlation with inhibition of self-primed DNA synthesis
  2. Beltz, H.; Clauss, C.; Piemont, E.; Ficheux, D.; Gorelick, R. J.; Roques, B.; Gabus, C.; Darlix, J. L.; de Rocquigny, H.; Mely, Y.
  3. Journal of Molecular Biology. 2005, MAY 20; 348(5): 1113-1126.
  1. 17.   Specific interactions between HIV-1 nucleocapsid protein and the TAR element
  2. Kanevsky, I.; Chaminade, F.; Ficheux, D.; Moumen, A.; Gorelick, R.; Negroni, M.; Darlix, J. L.; Fosse, P.
  3. Journal of Molecular Biology. 2005, MAY 20; 348(5): 1059-1077.
  1. 18.   Weak palindromic consensus sequences are a common feature found at the integration target sites of many retroviruses
  2. Wu, X. L.; Li, Y.; Crise, B.; Burgess, S. M.; Munroe, D. J.
  3. Journal of Virology. 2005, APR; 79(8): 5211-5214.
  1. 19.   Integrase of Mason-Pfizer monkey virus
  2. Snasel, J.; Krejcik, Z.; Jencova, V.; Rosenberg, I.; Ruml, T.; Alexandratos, J.; Gustchina, A.; Pichova, I.
  3. Febs Journal. 2005, JAN; 272(1): 203-216.
  1. 20.   Cooperative effect of Gag proteins p12 and capsid during early events of murine leukemia virus replication
  2. Lee, S. K.; Nagashima, K.; Hu, W. S.
  3. Journal of Virology. 2005 79(7): 4159-4169.
  1. 21.   Effects of mutations in the G tract of the human immunodeficiency virus type 1 polypurine tract on virus replication and RNase H cleavage
  2. Julias, J. G.; McWilliams, M. J.; Sarafianos, S. G.; Alvord, W. G.; Arnold, E.; Hughes, S. H.
  3. Journal of Virology. 2004, DEC; 78(23): 13315-13324.
  1. 22.   Model of full-length HIV-1 integrase complexed with viral DNA as template for anti-HIV drug design
  2. Karki, R. G.; Tang, Y.; Burke, T. R.; Nicklaus, M. C.
  3. Journal of Computer-Aided Molecular Design. 2004, DEC; 18(12): 739-760.
  1. 23.   Amino-terminal region of the human immunodeficiency virus type 1 nucleocapsid is required for human APOBEC3G packaging
  2. Luo, K.; Liu, B. D.; Xiao, Z. X.; Yu, Y. K.; Yu, X. H.; Gorelick, R.; Yu, X. F.
  3. Journal of Virology. 2004, NOV; 78(21): 11841-11852.
  1. 24.   Integration target site selection for retroviruses and transposable elements
  2. Wu, X.; Burgess, S. M.
  3. Cellular and Molecular Life Sciences. 2004, OCT; 61(19-20): 2588-2596.
  1. 25.   Mutations at position 184 of human immunodeficiency virus type-1 reverse transcriptase affect virus titer and viral DNA synthesis
  2. Julias, J. G.; Boyer, P. L.; McWilliams, M. J.; Alvord, W. G.; Hughes, S. H.
  3. Virology. 2004 322(1): 13-21.
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