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  1. 1.   In-utero exposure to zidovudine-containing antiretroviral therapy and clonal hematopoiesis in HIV-exposed uninfected newborns
  2. Lin, Shu-Hong; Wang, Youjin; Hartley, Stephen W.; Karyadi, Danielle M.; Lee, Olivia W.; Zhu, Bin; Zhou,Weiyin; Brown, Derek W.; Beilstein-Wedel, Erin; Hazra, Rohan; Kacanek, Deborah; Chadwick, Ellen G.; Marsit, Carmen J.; Poirier, Miriam C.; Brummel, Sean S.; Chanock, Stephen J.; Engels, Eric A.; Machiela, Mitchell J.
  3. AIDS. 2021, Aug 1; 35(10): 1525-1535.
  1. 2.   Association between zidovudine-containing antiretroviral therapy exposure in utero and leukocyte telomere length at birth
  2. Wang, Youjin; Brummel, Sean S; Beilstein-Wedel, Erin; Dagnall,Casey; Hazra, Rohan; Kacanek, Deborah; Chadwick, Ellen G; Marsit, Carmen J; Chanock, Stephen J; Savage, Sharon A; Poirier, Miriam C; Machiela, Mitchell J; Engels, Eric A
  3. AIDS (London, England). 2019, NOV 1; 33(13): 2091-2096.
  1. 3.   Role of low-frequency HIV-1 variants in failure of nevirapine-containing antiviral therapy in women previously exposed to single-dose nevirapine
  2. Boltz, V. F.; Zheng, Y.; Lockman, S.; Hong, F. Y.; Halvas, E. K.; McIntyre, J.; Currier, J. S.; Chibowa, M. C.; Kanyama, C.; Nair, A.; Owino-Ong'or, W.; Hughes, M.; Coffin, J. M.; Mellors, J. W.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2011, May; 108(22): 9202-9207.
  1. 4.   Phenotypic characterization of drug resistance-associated mutations in HIV-1 RT connection and RNase H domains and their correlation with thymidine analogue mutations
  2. Lengruber, R. B.; Delviks-Frankenberry, K. A.; Nikolenko, G. N.; Baumann, J.; Santos, A. F.; Pathak, V. K.; Soares, M. A.
  3. Journal of Antimicrobial Chemotherapy. 2011, Apr; 66(4): 702-708.
  1. 5.   Progressive Mitochondrial Compromise in Brains and Livers of Primates Exposed In Utero to Nucleoside Reverse Transcriptase Inhibitors (NRTIs)
  2. Divi, R. L.; Einem, T. L.; Fletcher, S. L. L.; Shockley, M. E.; Kuo, M. M.; St Claire, M. C.; Cook, A.; Nagashima, K.; Harbaugh, S. W.; Harbaugh, J. W.; Poirier, M. C.
  3. Toxicological Sciences. 2010, Nov; 118(1): 191-201.
  1. 6.   Interferon-alpha Produces Significant Decreases in HIV Load
  2. Tavel, J. A.; Huang, C. Y.; Shen, J.; Metcalf, J. A.; Dewar, R.; Shah, A.; Vasudevachari, M. B.; Follmann, D. A.; Herpin, B.; Davey, R. T.; Polis, M. A.; Kovacs, J.; Masur, H.; Lane, H. C.
  3. Journal of Interferon and Cytokine Research. 2010, Jul; 30(7): 461-464.
  1. 7.   A Novel Molecular Mechanism of Dual Resistance to Nucleoside and Nonnucleoside Reverse Transcriptase Inhibitors
  2. Nikolenko, G. N.; Delviks-Frankenberry, K. A.; Pathak, V. K.
  3. Journal of Virology. 2010, May; 84(10): 5238-5249.
  1. 8.   The Path Well Traveled: Using Mammalian Retroviruses to Guide Research on XMRV
  2. Lee, K.; Jones, K. S.
  3. Molecular Interventions. 2010, Feb; 10(1): 20-24.
  1. 9.   HIV-1 reverse transcriptase connection subdomain mutations reduce template RNA degradation and enhance AZT excision
  2. Delviks-Frankenberry, K. A.; Nikolenko, G. N.; Boyer, P. L.; Hughes, S. H.; Coffin, J. M.; Jere, A.; Pathak, V. K.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2008 105(31): 10943-10948.
  1. 10.   Erythrocebus patas monkey offspring exposed perinatally to NRTIs sustain skeletal muscle mitochondrial compromise at birth and at 1 year of age
  2. Divi, R. L.; Leonard, S. L.; Walker, B. L.; Kuo, M. M.; Shockley, M. E.; St Claire, M. C.; Nagashima, K.; Harbaugh, S. W.; Harbaugh, J. W.; Poirier, M. C.
  3. Toxicological Sciences. 2007, Sep; 99(1): 203-213.
  1. 11.   Selection of mutations in the connection and RNase H domains of human immunodeficiency virus type 1 reverse transcriptase that increase resistance to 3 '-azido-3 '-dideoxythymidine
  2. Brehm, J. H.; Koontz, D.; Meteer, J. D.; Pathak, V.; Sluis-Cremer, N.; Mellors, J. W.
  3. Journal of Virology. 2007, Aug; 81(15): 7852-7859.
  1. 12.   Mutations in the connection domain of HIV-1 reverse transcriptase increase 3 '-azido-3 '-deoxythymidine resistance
  2. Nikolenko, G. N.; Delviks-Frankenberry, K. A.; Palmer, S.; Maldarelli, F.; Fivash, M. J.; Coffin, J. M.; Pathak, V. K.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2007, Jan; 104(1): 317-322.
  1. 13.   Transplacentally exposed human and monkey newborn infants show similar evidence of nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity
  2. Divi, R. L.; Leonard, S. L.; Kuo, M. M.; Nagashima, K.; Thamire, C.; St Claire, M. C.; Wade, N. A.; Walker, V. E.; Poirier, M. C.
  3. Environmental and Molecular Mutagenesis. 2007, Apr-May; 48(3-4): 201-209.
  1. 14.   Effects of the Delta 67 complex of mutations in human immunodeficiency virus type 1 reverse transcriptase on nucleoside analog excision
  2. Boyer, P. L.; Imamichi, T.; Sarafianos, S. G.; Arnold, E.; Hughes, S. H.
  3. Journal of Virology. 2004, SEP; 78(18): 9987-9997.
  1. 15.   Mitochondrial damage and DNA depletion in cord blood and umbilical cord from infants exposed in utero to Combivir
  2. Divi, R. L.; Walker, V. E.; Wade, N. A.; Nagashima, K.; Seilkopf, S. K.; Adams, M. E.; Nesel, C. J.; O'Neill, J. P.; Abrams, E. J.; Poirier, M. C.
  3. Aids. 2004 18(7): 1013-1021.
  1. 16.   Mitochondrial toxicity in fetal Erythrocebus patas monkeys exposed transplacentally to zidovudine plus lamivudine
  2. Gerschenson, M.; Nguyen, V.; Ewings, E. L.; Ceresa, A.; Shaw, J. A.; St Claire, M. C.; Nagashima, K.; Harbaugh, S. W.; Harbaugh, J. W.; Olivero, O. A.; Divi, R. L.; Albert, P. S.; Poirier, M. C.
  3. Aids Research and Human Retroviruses. 2004 20(1): 91-100.
  1. 17.   The Delta 67 complex of mutations enhances the ability of HIV-1 reverse transcriptase to excise zidovudine, stavudine and PMPA from blocked primers
  2. Boyer, P. L.; Imamichi, T.; Sarafianos, S. G.; Arnold, E.; Hughes, S. H.
  3. Antiviral Therapy. 2003, JUN; 8(3): U42, Abstract 30-U42, Abstract 30.
  1. 18.   Retroviral recombination: Review of genetic analyses
  2. Hu, W. S.; Rhodes, T.; Dang, Q.; Pathak, V.
  3. Frontiers in Bioscience. 2003 8: D143-D155.
  1. 19.   Susceptibility of human T cell leukemia virus type I to nucleoside reverse transcriptase inhibitors
  2. Hill, S. A.; Lloyd, P. A.; McDonald, S.; Wykoff, J.; Derse, D.
  3. Journal of Infectious Diseases. 2003 188(3): 424-427.
  1. 20.   Eradication of human immunodeficiency virus type 1-infected cells by a combination of antimetabolic cytotoxic chemotherapy and antiviral chemotherapy in vitro: A pilot study
  2. Yang, Q. E.; Li, K. G.; Mikovits, J. A.
  3. Journal of Infectious Diseases. 2002 186(5): 706-709.
  1. 21.   Macrophages relate presynaptic and postsynaptic damage in simian immunodeficiency virus encephalitis
  2. Bissel, S. J.; Wang, G. J.; Ghosh, M.; Reinhart, T. A.; Capuano, S.; Cole, K. S.; Murphey-Corb, M.; Piatak, M.; Lifson, J. D.; Wiley, C. A.
  3. American Journal of Pathology. 2002 160(3): 927-941.
  1. 22.   Relative replication fitness of a high-level 3 '-azido-3 '- deoxythymidine-resistant variant of human immunodeficiency virus type 1 possessing an amino acid deletion at codon 67 and a novel substitution (Thr -> Gly) at codon 69
  2. Imamichi, T.; Berg, S. C.; Imamichi, H.; Lopez, J. C.; Metcalf, J. A.; Falloon, J.; Lane, H. C.
  3. Journal of Virology. 2000 74(23): 10958-10964.
  1. 23.   Oxidative DNA damage in fetal tissues after transplacental exposure to 3 '-azido-3 '-deoxythymidine (AZT)
  2. Bialkowska, A.; Bialkowski, K.; Gerschenson, M.; Diwan, B. A.; Jones, A. B.; Olivero, O. A.; Poirier, M. C.; Anderson, L. M.; Kasprzak, S.; Sipowicz, M. A.
  3. Carcinogenesis. 2000 21(5): 1059-1062.
  1. 24.   Immunologic and virologic effects of subcutaneous interleukin 2 in combination with antiretroviral therapy - A randomized controlled trial
  2. Davey, R. T.; Murphy, R. L.; Graziano, F. M.; Boswell, S. L.; Pavia, A. T.; Cancio, M.; Nadler, J. P.; Chaitt, D. G.; Dewar, R. L.; Sahner, D. K.; Duliege, A. M.; Capra, W. B.; Leong, W. P.; Giedlin, M. A.; Lane, H. C.; Kahn, J. O.
  3. Jama-Journal of the American Medical Association. 2000 284(2): 183-189.
  1. 25.   Absence of structural or functional alterations in male and female reproductive organs of F1 and F2 generations derived from female mice exposed to 3 '-azido-3 '-deoxythymidine during pregnancy
  2. Diwan, B. A.; Olivero, O. A.; Poirier, M. C.
  3. Toxicology Letters. 2000 115(1): 9-15.
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