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  1. 1.   DNA intercalator korkormicin A preferentially kills tumor cells expressing wild type p53
  2. Kitagaki, J.; Yang, Y. L.
  3. Biochemical and Biophysical Research Communications. 2011, Oct; 414(1): 186-191.
  1. 2.   Nodal Signaling Recruits the Histone Demethylase Jmjd3 to Counteract Polycomb-Mediated Repression at Target Genes
  2. Dahle, O.; Kumar, A.; Kuehn, M. R.
  3. Science Signaling. 2010, Jun; 3(127): 8.
  1. 3.   ANTIVIRAL COMPOUNDS IN THE PIPELINE TO TACKLE H1N1 INFLUENZA INFECTION
  2. Beigel, J. H.
  3. Drugs of the Future. 2010, May; 35(5): 385-392.
  1. 4.   Reverse transcriptase in motion: Conformational dynamics of enzyme-substrate interactions
  2. Gotte, M.; Rausch, J. W.; March, B.; Sarafianos, S.; Le Grice, S. F. J.
  3. Biochimica Et Biophysica Acta-Proteins and Proteomics. 2010, May; 1804(5): 1202-1212.
  1. 5.   Symmetrical alpha-bromoacryloylamido diaryldienone derivatives as a novel series of antiproliferative agents. Design, synthesis and biological evaluation
  2. Romagnoli, R.; Baraldi, P. G.; Cruz-Lopez, O.; Cara, C. L.; Carrion, M. D.; Balzarini, J.; Hamel, E.; Basso, G.; Bortolozzi, R.; Viola, G.
  3. Bioorganic & Medicinal Chemistry Letters. 2010, May; 20(9): 2733-2739.
  1. 6.   Novel microtubule-interacting phenoxy pyridine and phenyl sulfanyl pyridine analogues for cancer therapy
  2. Anchoori, R. K.; Kortenhorst, M.; Hidalgo, M.; Sarkar, T.; Hallur, G.; Bai, R. L.; Van Diest, P. J.; Hamel, E.; Khan, S. R.
  3. Journal of Medicinal Chemistry. 2008 51(19): 5953-5957.
  1. 7.   Madurahydroxylactone derivatives as dual inhibitors of human immunodeficiency virus type 1 integrase and RNase H
  2. March, C.; Beutler, J. A.; Wamiru, A.; Budihas, S.; Mollmann, U.; Heinisch, L.; Mellors, J. W.; Le Grice, S. F.; Pommier, Y.
  3. Antimicrobial Agents and Chemotherapy. 2008 52(1): 361-364.
  1. 8.   Development of two novel benzoylphenylurea sulfur analogues and evidence that the microtubule-associated protein tau is predictive of their activity in pancreatic cancer
  2. Jimeno, A.; Hallur, G.; Chan, A.; Zhang, X. F.; Cusatis, G.; Chan, F.; Shah, P.; Chen, R. B.; Hamel, E.; Garrett-Mayer, E.; Khan, S.; Hidalgo, M.
  3. Molecular Cancer Therapeutics. 2007, May; 6(5): 1509-1516.
  1. 9.   Alarmins initiate host Defense
  2. Oppenheim, J. J.; Tewary, P.; de la Rosa, G.; Yang, D.
  3. Immune-Mediated Diseases: From Theory to Therapy. 2007; 601 : 185-194.
  1. 10.   Studies of the biological properties of human beta-defensin 1
  2. Pazgier, M.; Prahl, A.; Hoover, D. M.; Lubkowski, J.
  3. Journal of Biological Chemistry. 2007, Jan; 282(3): 1819-1829.
  1. 11.   Effects of selenium supplementation on expression of glutathione peroxidase isoforms in cultured human lung adenocarcinoma cell lines
  2. Romanowska, M.; Kikawa, K. D.; Fields, J. R.; Maciag, A.; North, S. L.; Shiao, Y. H.; Kasprzak, K. S.; Anderson, L. M.
  3. Lung Cancer. 2007, Jan; 55(1): 35-42.
  1. 12.   Mining the NCI antiviral compounds for HIV-1 integrase inhibitors
  2. Deng, J. X.; Kelley, J. A.; Barchi, J. J.; Sanchez, T.; Dayam, R.; Pommier, Y.; Neamati, N.
  3. Bioorganic & Medicinal Chemistry. 2006, JUN 1; 14(11): 3785-3792.
  1. 13.   Proteasome inhibition to maximize the apoptotic potential of cytokine therapy for murine neuroblastoma tumors
  2. Khan, T.; Stauffer, J. K.; Williams, R.; Hixon, J. A.; Salcedo, R.; Lincoln, E.; Back, T. C.; Powell, D.; Lockett, S.; Arnold, A. C.; Sayers, T. J.; Wigginton, J. M.
  3. Journal of Immunology. 2006, MAY 15; 176(10): 6302-6312.
  1. 14.   Effects of select PM-associated metals on alveolar macrophage phosphorylated ERK1 and-2 and iNOS expression during ongoing alteration in iron homeostasis
  2. Prophete, C.; Maciejczyk, P.; Salnikow, K.; Gould, T.; Larson, T.; Koenig, J.; Jaques, P.; Sioutas, C.; Lippmann, M.; Cohen, M.
  3. Journal of Toxicology & Environmental Health-Part A-Current Issues. 2006, MAY 15; 69(10): 935-951.
  1. 15.   gamma-cleavage-independent functions of presenilin, nicastrin, and aph-1 regulate cell-junction organization and prevent tau toxicity in vivo
  2. Doglio, L. E.; Kanwar, R.; Jackson, G. R.; Perez, M.; Avila, J.; Dingwal, C.; Dotti, C. G.; Fortini, M. E.; Feiguin, F.
  3. Neuron. 2006, MAY 4; 50(3): 359-375.
  1. 16.   Recombinant production of anti-HIV protein, griffithsin, by auto-induction in a fermentor culture
  2. Giomarelli, B.; Schumacher, K. M.; Taylor, T. E.; Sowder, R. C.; Hartley, J. L.; McMahon, J. B.; Mori, T.
  3. Protein Expression and Purification. 2006, MAY; 47(1): 194-202.
  1. 17.   Development of a quantitative cell-based ELISA, for a humanized anti-IL-2/IL-15 receptor beta antibody (HuMik beta(1)), and correlation with functional activity using an antigen-transfected murine cell line
  2. Yang, X. Y.; Chen, E.; Jiang, H. G.; Hartmann, W. K.; Mitra, G.; Hecht, T.; Soman, G.
  3. Journal of Immunological Methods. 2006, APR 20; 311(1-2): 71-80.
  1. 18.   Oncogenic met receptor induces cell-cycle progression in Xenopus oocytes independent of direct Grb2 and shc binding or Mos synthesis, but requires phosphatidylinositol 3-kinase and Raf signaling
  2. Mood, K.; Saucier, C.; Ishimura, A.; Bong, Y. S.; Lee, H. S.; Park, M.; Daar, I. O.
  3. Journal of Cellular Physiology. 2006, APR; 207(1): 271-285.
  1. 19.   Generation and characterization of telomere length maintenance in tankyrase 2-deficient mice
  2. Chiang, Y. J.; Nguyen, M. L.; Gurunathan, S.; Kaminker, P.; Tessarollo, L.; Campisi, J.; Hodes, R. J.
  3. Molecular and Cellular Biology. 2006, MAR; 26(6): 2037-2043.
  1. 20.   Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5
  2. Lee, S.; Tsai, Y. C.; Mattera, R.; Smith, W. J.; Kostelansky, M. S.; Weissman, A. M.; Bonifacino, J. S.; Hurley, J. H.
  3. Nature Structural & Molecular Biology. 2006, MAR; 13(3): 264-271.
  1. 21.   Inhibition of transcription factor NF-kappa B signaling proteins IKK beta and p65 through specific cysteine residues by epoxyquinone A monomer: Correlation with its anti-cancer cell growth activity
  2. Liang, M. C.; Bardhan, S.; Pace, E. A.; Rosman, D.; Beutler, J. A.; Porco, J. A.; Gilmore, T. D.
  3. Biochemical Pharmacology. 2006, FEB 28; 71(5): 634-645.
  1. 22.   Synthesis, processing, and composition of the virion-associated HTLV-1 reverse transcriptase
  2. Mitchell, M. S.; Tozser, J.; Princler, G.; Lloyd, P. A.; Auth, A.; Derse, D.
  3. Journal of Biological Chemistry. 2006, FEB 17; 281(7): 3964-3971.
  1. 23.   CB694, a novel antimitotic with antitumor activities
  2. Weiderhold, K. N.; Randall-Hiubek, D. A.; Polin, L. A.; Hamel, E.; Mooberry, S. L
  3. International Journal of Cancer. 2006, FEB 15; 118(4): 1032-1040.
  1. 24.   Activation of toll-like receptor 2 on microglia promotes cell uptake of Alzheimer disease-associated amyloid beta peptide
  2. Chen, K. Q.; Iribarren, P.; Hu, J. Y.; Chen, J. H.; Gong, W. H.; Cho, E. H.; Lockett, S.; Dunlop, N. M.; Wang, J. M.
  3. Journal of Biological Chemistry. 2006, FEB 10; 281(6): 3651-3659.
  1. 25.   PABA/NO as an anticancer lead: Analogue synthesis, structure revision, solution chemistry, reactivity toward glutathione, and in vitro activity
  2. Saavedra, J. E.; Srinivasan, A.; Buzard, G. S.; Davies, K. M.; Waterhouse, D. J.; Inami, K.; Wilde, T. C.; Citro, M. L.; Cuellar, M.; Deschamps, J. R.; Parrish, D.; Shami, P. J.; Findlay, V. J.; Townsend, D. M.; Tew, K. D.; Singh, S.; Jia, L.; Ji, X. H.; Keefer, L. K.
  3. Journal of Medicinal Chemistry. 2006, FEB 9; 49(3): 1157-1164.
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