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  1. 1.   Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5
  2. Lee, S.; Tsai, Y. C.; Mattera, R.; Smith, W. J.; Kostelansky, M. S.; Weissman, A. M.; Bonifacino, J. S.; Hurley, J. H.
  3. Nature Structural & Molecular Biology. 2006, MAR; 13(3): 264-271.
  1. 2.   IL-3-mediated TNF production is necessary for mast cell development
  2. Wright, H. V.; Bailey, D.; Kashyap, M.; Kepley, C. L.; Drutskaya, M. S.; Nedospasov, S. A.; Ryan, J. J.
  3. Journal of Immunology. 2006, FEB 15; 176(4): 2114-2121.
  1. 3.   Novel human monoclonal antibodies to insulin-like growth factor (IGH)-II that potently inhibit the IGF receptor type I signal transduction function
  2. Feng, Y.; Zhu, Z. Y.; Xiao, X. D.; Choudhry, V.; Barrett, J. C.; Dimitrov, D. S.
  3. Molecular Cancer Therapeutics. 2006, JAN; 5(1): 114-120.
  1. 4.   Nucleic acid binding and chaperone properties of HIV-1 Gag and nucleocapsid proteins
  2. Cruceanu, M.; Urbaneja, M. A.; Hixson, C. V.; Johnson, D. G.; Datta, S. A.; Fivash, M. J.; Stephen, A. G.; Fisher, R. J.; Gorelick, R. J.; Casas-Finet, J. R.; Rein, A.; Rouzina, I.; Williams, M. C.
  3. Nucleic Acids Research. 2006 34(2): 593-605.
  1. 5.   Actin is the primary cellular receptor of bistramide A
  2. Statsuk, A. V.; Bai, R. L.; Baryza, J. L.; Verma, V. A.; Hamel, E.; Wender, P. A.; Kozmin, S. A.
  3. Nature Chemical Biology. 2005, DEC; 1(7): 383-388.
  1. 6.   Gateway vectors for the production of combinatorially-tagged His(6)-MBP fusion proteins in the cytoplasm and periplasm of Escherichia Coli
  2. Nallamsetty, S.; Austin, B. P.; Penrose, K. J.; Waugh, D. S.
  3. Protein Science. 2005, DEC; 14(12): 2964-2971.
  1. 7.   Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain
  2. Phan, J.; Shi, Z. D.; Burke, T. R.; Waugh, D. S.
  3. Journal of Molecular Biology. 2005, OCT 14; 353(1): 104-115.
  1. 8.   Analysis of albumin-associated peptides and proteins from ovarian cancer patients
  2. Lowenthal, M. S.; Mehta, A. I.; Frogale, K.; Bandle, R. W.; Araujo, R. P.; Hood, B. L.; Veenstra, T. D.; Conrads, T. P.; Goldsmith, P.; Fishman, D.; Petricoin, E. F.; Liotta, L. A
  3. Clinical Chemistry. 2005, OCT; 51(10): 1933-1945.
  1. 9.   Synthesis of a C-terminally biotinylated macrocyclic peptide mimetic exhibiting high Grb2 SH2 domain-binding affinity
  2. Shi, Z. D.; Liu, H. P.; Zhang, M. C.; Worthy, K. M.; Bindu, L.; Yang, D. J.; Fisher, R. J.; Burke, T. R.
  3. Bioorganic & Medicinal Chemistry. 2005, JUL 1; 13(13): 4200-4208.
  1. 10.   Examination of phosphoryl-mimicking functionalities within a macrocyclic Grb2 SH2 domain-binding platform
  2. Kang, S. U.; Shi, Z. D.; Worthy, K. M.; Bindu, L. K.; Dharmawardana, P. G.; Choyke, S. J.; Bottaro, D. P.; Fisher, R. J.; Burke, T. R.
  3. Journal of Medicinal Chemistry. 2005, JUN 16; 48(12): 3945-3948.
  1. 11.   Efficient killing of CD22(+) tumor cells by a humanized diabody-RNase fusion protein
  2. Krauss, J.; Arndt, M. A. E.; Vu, B. K.; Newton, D. L.; Seeber, S.; Rybak, S. M.
  3. Biochemical and Biophysical Research Communications. 2005, JUN 3; 331(2): 595-602.
  1. 12.   Making the most of affinity tags
  2. Waugh, D. S.
  3. Trends in Biotechnology. 2005, JUN; 23(6): 316-320.
  1. 13.   Binding affinity difference induced by the stereochemistry of the sulfoxide bridge of the cyclic peptide inhibitors of Grb2-SH2 domain: NMR studies for the structural origin
  2. Shi, Y. H.; Song, Y. L.; Lin, D. H.; Tan, J. Z.; Roller, P. P.; Li, Q.; Long, Y. Q.; Song, G. Q.
  3. Biochemical and Biophysical Research Communications. 2005, MAY 20; 330(4): 1254-1261.
  1. 14.   Qualitative assessment Of IC50 values of inhibitors of the neuronal nicotinic acetylcholine receptor using a single chromatographic experiment and multivariate cluster analysis
  2. Jozwiak, K.; Moaddel, R.; Yamaguchi, R.; Ravichandran, S.; Collins, J. R.; Wainer, I. W
  3. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences. 2005, MAY 5; 819(1): 169-174.
  1. 15.   Substrate specificity of the human protein phosphatase 2C delta Wip1
  2. Yamaguchi, H.; Minopoli, G.; Demidov, O. N.; Chatterjee, D. K.; Anderson, C. W.; Durell, S. R.; Appella, E.
  3. Biochemistry. 2005, APR 12; 44(14): 5285-5294.
  1. 16.   The N-terminal peptide of the Kaposi's sarcoma-associated herpesvirus (KSHV)-cyclin determines substrate specificity
  2. Kaldis, P.
  3. Journal of Biological Chemistry. 2005, MAR 25; 280(12): 11165-11174.
  1. 17.   Purified Bacillus anthracis lethal toxin complex formed in Vitro and during infection exhibits functional and biological activity
  2. Panchal, R. G.; Halverson, K. M.; Ribot, W.; Lane, D.; Kenny, T.; Abshire, T. G.; Ezzell, J. W.; Hoover, T. A.; Powell, B.; Little, S.; Kasianowicz, J. J.; Bavari, S.
  3. Journal of Biological Chemistry. 2005, MAR 18; 280(11): 10834-10839.
  1. 18.   Utilization of a nitrobenzoxadiazole (NBD) fluorophore in the design of a Grb2 SH2 domain-binding peptide mimetic
  2. Shi, Z. D.; Karki, R. G.; Oishi, S.; Worthy, K. M.; Bindu, L. K.; Dharmawardana, P. G.; Nicklaus, M. C.; Bottaro, D. P.; Fisher, R. J.; Burke, T. R.
  3. Bioorganic & Medicinal Chemistry Letters. 2005, MAR 1; 15(5): 1385-1388.
  1. 19.   Design and synthesis of conformationally constrained Grb2 SH2 domain binding peptides employing alpha-methylphenylalanyl based phosphotyrosyl mimetics
  2. Oishi, S.; Karki, R. G.; Kang, S. U.; Wang, X. Z.; Worthy, K. M.; Bindu, L. K.; Nicklaus, M. C.; Fisher, R. J.; Burke, T. R.
  3. Journal of Medicinal Chemistry. 2005, FEB 10; 48(3): 764-772.
  1. 20.   Structure-based design, synthesis and biochemical testing of novel and potent Smac peptido-mimetics
  2. Sun, H. Y.; Nikolovska-Coleska, Z.; Chen, J. Y.; Yang, C. Y.; Tomita, Y.; Pan, H. G.; Yoshioka, Y.; Krajewski, K.; Roller, P. P.; Wang, S. M.
  3. Bioorganic & Medicinal Chemistry Letters. 2005, FEB 1; 15(3): 793-797.
  1. 21.   Magnitude of the hydrophobic effect at central versus peripheral sites in protein-protein interfaces
  2. Li, Y. L.; Huang, Y. P.; Swaminathan, C. P.; Smith-Gill, S. J.; Mariuzza, R. A.
  3. Structure. 2005, FEB; 13(2): 297-307.
  1. 22.   Quantitative proteomic analysis of sokotrasterol sulfate-stimulated primary human endothelial cells
  2. Karsan, A.; Pollet, I.; Yu, L. R.; Chan, K. C.; Conrads, T. P.; Lucas, D. A.; Andersen, R.; Veenstra, T.
  3. Molecular & Cellular Proteomics. 2005, FEB; 4(2): 191-204.
  1. 23.   Evaluation of macrocyclic Grb2 SH2 domain-binding peptide mimetics prepared by ring-closing metathesis of C-terminal allylglycines with an N-terminal beta-vinyl-substituted phosphotyrosyl mimetic
  2. Oishi, S.; Karki, R. G.; Shi, Z. D.; Worthy, K. M.; Bindu, L.; Chertov, O.; Esposito, D.; Frank, P.; Gillette, W. K.; Maderia, M.; Hartley, J.; Nicklaus, M. C.; Barchi, J. J.; Fisher, R. J.; Burke, T. R.
  3. Bioorganic & Medicinal Chemistry. 2005 13(7): 2431-2438.
  1. 24.   Utilization of a common pathway for the synthesis of high affinity macrocyclic Grh2 SH2 domain-binding peptide mimetics that differ in the configuration at one ring junction
  2. Shi, Z. D.; Karki, R. G.; Worthy, K. M.; Bindu, L. K.; Nicklaus, M. C.; Fisher, R. J.; Burke, T. R.
  3. Chemistry & Biodiversity. 2005 2(4): 447-456.
  1. 25.   Preclinical manufacture of an anti-HER2 scFv-PEG-DSPE, liposome-inserting conjugate. 1. Gram-scale production and purification
  2. Nellis, D. F.; Ekstrom, D. L.; Kirpotin, D. B.; Zhu, J. W.; Andersson, R.; Broadt, T. L.; Ouellette, T. F.; Perkins, S. C.; Roach, J. M.; Drummond, D. C.; Hong, K. L.; Marks, J. D.; Park, J. W.; Giardina, S. L.
  3. Biotechnology Progress. 2005, JAN-FEB; 21(1): 205-220.
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