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  1. 1.   ERK Allosteric Activation: The Importance of Two Ordered Phosphorylation Events
  2. Regev,Clil; Jang,Hyunbum; Nussinov,Ruth
  3. Journal of Molecular Biology. 2025, Apr 09; 169130.
  1. 2.   Allosteric regulation of autoinhibition and activation of c-Abl
  2. Liu,Yonglan; Zhang,Mingzhen; Tsai,Chung-Jung; Jang,Hyunbum; Nussinov,Ruth
  3. Computational and Structural Biotechnology Journal. 2022 20: 4257-4270.
  1. 3.   The Role of Conformational Dynamics in the Recognition and Regulation of Ubiquitination
  2. Khago, Domarin; Fucci,Ian; Byrd,Robert
  3. Molecules (Basel, Switzerland). 2020, Dec 15; 25(24):
  1. 4.   Peptide-MHC Binding Reveals Conserved Allosteric Sites in MHC Class I- and Class II-Restricted T Cell Receptors (TCRs)
  2. He, Yanan; Agnihotri, Pragati; Rangarajan, Sneha; Chen, Yihong; Kerzic, Melissa C.; Ma, Buyong; Nussinov,Ruth; Mariuzza, Roy A.; Orban, John
  3. JOURNAL OF MOLECULAR BIOLOGY. 2020, Dec 4; 432(24):
  1. 5.   Autoinhibition can identify rare driver mutations and advise pharmacology
  2. Nussinov,Ruth; Tsai,Chung-Jung; Jang,Hyunbum
  3. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2020, Jan; 34(1): 16-29.
  1. 6.   Does Ras Activate Raf and PI3K Allosterically?
  2. Nussinov,Ruth; Tsai,Chung-Jung; Jang,Hyunbum
  3. Frontiers in oncology. 2019, Nov 15; 9
  1. 7.   Allostery in Its Many Disguises: From Theory to Applications
  2. Wodak, Shoshana J.; Paci, Emanuele; Dokholyan, Nikolay; Berezovsky, Igor N.; Horovitz, Amnon; Li, Jing; Hilser, Vincent J.; Behar, Ivet; Karanicolas, John; Stock, Gerhard; Hamm, Peter; Stote, Roland H.; Eberhardt, Jerome; Chebaro, Yassmine; Dejaegere, Annick; Cecchini, Marco; Changeux, Jean-Pierre; Bolhuis, Peter G.; Vreede, Jocelyne; Faccioli, Pietro; Orioli, Simone; Ravasio, Riccardo; Yen, Le; Brito, Carolina; Wyart, Matthieu; Gkeka, Paraskevi; Rivalta, Ivan; Palermo, Giulia; Mccammon, J. Andrew; Panecka-Hofman, Joanna; Wade, Rebecca C.; Di Pizio, Antonella; Niv, Masha Y.; Nussinov,Ruth; Tsai,Chung-Jung; Jang,Hyunbum; Padhorny, Dzmitry; Kozakov, Dima; Mcleish, Tom
  3. Structure (London, England : 1993). 2019, Apr 2; 27(4): 566-578.
  1. 8.   Antigen binding allosterically promotes Fc receptor recognition
  2. Zhao, Jun; Nussinov, Ruth; Ma, Buyong
  3. mAbs. 2019, Jan; 11(1): 58-74.
  1. 9.   Conformational Dynamics and Allostery in E2:E3 Interactions Drive Ubiquitination: gp78 and Ube2g2
  2. Chakrabarti, Kalyan S; Li, Jess; Das, Ranabir; Byrd, Robert
  3. Structure (London, England : 1993). 2017, May 2; 25(5): 794-805.
  1. 10.   Allostery modulates the beat rate of a cardiac pacemaker
  2. Tsai, Chung-Jung; Nussinov, Ruth
  3. The Journal of Biological Chemistry. 2017, Apr 14; 292(15): 6429-6430.
  1. 11.   Computational Tools for Allosteric Drug Discovery: Site Identification and Focus Library Design.
  2. Huang, Wenkang; Nussinov, Ruth; Zhang, Jian
  3. Methods in molecular biology (Clifton, N.J.). 2017 1529: 439-446.
  1. 12.   Allosteric modulators can restore function in an amino acid neurotransmitter receptor by slightly altering intra-molecular communication pathways
  2. Nussinov, R.
  3. British Journal of Pharmacology. 2012, Apr; 165(7): 2110-2112.
  1. 13.   Conformational Control of the Binding of the Transactivation Domain of the MLL Protein and c-Myb to the KIX Domain of CREB
  2. Korkmaz, E. N.; Nussinov, R.; Haliloglu, Y.
  3. Plos Computational Biology. 2012, Mar; 8(3):
  1. 14.   How do dynamic cellular signals travel long distances?
  2. Nussinov, R.
  3. Molecular Biosystems. 2012, Jan 1; 8(1): 22-26.
  1. 15.   Gene-specific transcription activation via long-range allosteric shape-shifting
  2. Tsai, C. J.; Nussinov, R.
  3. Biochemical Journal. 2011, Oct; 439: 15-25.
  1. 16.   Alternative Allosteric Mechanisms Can Regulate the Substrate and E2 in SUMO Conjugation
  2. Karaca, E.; Tozluoglu, M.; Nussinov, R.; Haliloglu, T.
  3. Journal of Molecular Biology. 2011, Mar; 406(4): 620-630.
  1. 17.   Rbx1 Flexible Linker Facilitates Cullin-RING Ligase Function Before Neddylation and After Deneddylation
  2. Liu, J.; Nussinov, R.
  3. Biophysical Journal. 2010, Aug; 99(3): 736-744.
  1. 18.   Why Does Binding of Proteins to DNA or Proteins to Proteins Not Necessarily Spell Function?
  2. Ma, B. Y.; Tsai, C. J.; Pan, Y. P.; Nussinov, R.
  3. Acs Chemical Biology. 2010, Mar; 5(3): 265-272.
  1. 19.   Translocation by multi-subunit RNA polymerases
  2. Kireeva, M.; Kashlev, M.; Burton, Z. F.
  3. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms. 2010, May-Jun; 1799(5-6): 389-401.
  1. 20.   The Origin of Allosteric Functional Modulation: Multiple Pre-existing Pathways
  2. del Sol, A.; Tsai, C. J.; Ma, B. Y.; Nussinov, R.
  3. Structure. 2009 17(8): 1042-1050.
  1. 21.   The Mechanism of Ubiquitination in the Cullin-RING E3 Ligase Machinery: Conformational Control of Substrate Orientation
  2. Liu, J.; Nussinov, R.
  3. Plos Computational Biology. 2009 5(10):
  1. 22.   Cooperativity Dominates the Genomic Organization of p53-Response Elements: A Mechanistic View
  2. Pan, Y. P.; Nussinov, R.
  3. Plos Computational Biology. 2009 5(7):
  1. 23.   How do transcription factors select specific binding sites in the genome?
  2. Pan, Y. P.; Tsai, C. J.; Ma, B. Y.; Nussinov, R.
  3. Nature Structural & Molecular Biology. 2009 16(11): 1118-1120.
  1. 24.   Modular architecture of protein structures and allosteric communications: potential implications for signaling proteins and regulatory linkages
  2. del Sol, A.; Arauzo-Bravo, M. J.; Moya, D. A.; Nussinov, R.
  3. Genome Biology. 2007 8(5):
  1. 25.   Is allostery an intrinsic property of all dynamic proteins?
  2. Gunasekaran, K.; Ma, B. Y.; Nussinov, R.
  3. Proteins-Structure Function and Bioinformatics. 2004, NOV 15; 57(3): 433-443.
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