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  1. 1.   The conserved salt bridge in human alpha-defensin 5 is required for its precursor processing and proteolytic stability
  2. Rajabi, M.; de Leeuw, E.; Pazgier, M.; Li, J.; Lubkowski, J.; Lu, W.
  3. Journal of Biological Chemistry. 2008 283(31): 21509-21518.
  1. 2.   Toward understanding the cationicity of defensins - Arg and Lys versus their noncoded analogs
  2. Zou, G. Z.; de Leeuw, E.; Li, C.; Pazgier, M.; Li, C. Q.; Zeng, P. Y.; Lu, W. Y.; Lubkowski, J.; Lu, W. Y.
  3. Journal of Biological Chemistry. 2007, Jul; 282(27): 19653-19665.
  1. 3.   Human defensins: synthesis and structural properties
  2. Pazgier, M.; Li, X.; Lu, W.; Lubkowski, J.
  3. Current Pharmaceutical Design. 2007 13(30): 3096-3118.
  1. 4.   Studies of the biological properties of human beta-defensin 1
  2. Pazgier, M.; Prahl, A.; Hoover, D. M.; Lubkowski, J.
  3. Journal of Biological Chemistry. 2007, Jan; 282(3): 1819-1829.
  1. 5.   Crystal structures of human alpha-defensins HNP4, HD5, and HD6
  2. Szyk, A.; Wu, Z. B.; Tucker, K.; Yang, D.; Lu, W. Y.; Lubkowski, J.
  3. Protein Science. 2006, Dec; 15(12): 2749-2760.
  1. 6.   Expression and purification of recombinant human alpha-defensins in Escherichia coli
  2. Pazgier, M.; Lubkowski, J.
  3. Protein Expression and Purification. 2006, Sep; 49(1): 1-8.
  1. 7.   theta-defensins prevent HIV-1 Env-mediated fusion by binding gp41 and blocking 6-helix bundle formation
  2. Gallo, S. A.; Wang, W.; Rawat, S. S.; Jung, G.; Waring, A. J.; Cole, A. M.; Lu, H.; Yan, X. X.; Daly, N. L.; Craik, D. J.; Jiang, S. B.; Lehrer, R. I.; Blumenthal, R.
  3. Journal of Biological Chemistry. 2006, Jul; 281(27): 18787-18792.
  1. 8.   Human beta-defensins
  2. Pazgier, M.; Hoover, D. M.; Yang, D.; Lu, W.; Lubkowski, J.
  3. Cellular and Molecular Life Sciences. 2006, Jun; 63(11): 1294-1313.
  1. 9.   Human alpha-defensins block papillomavirus infection
  2. Buck, C. B.; Day, P. M.; Thompson, C. D.; Lubkowski, J.; Lu, W. Y.; Lowy, D. R.; Schiller, J. T.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2006, JAN 31; 103(5): 1516-1521.
  1. 10.   Inhibition of pathologic retinal neovascularization by alpha-defensins
  2. Economopoulou, M.; Bdeir, K.; Cines, D. B.; Fogt, F.; Bdeir, Y.; Lubkowski, J.; Lu, W. Y.; Preissner, K. T.; Hammes, H. P.; Chavakis, T.
  3. Blood. 2005, DEC 1; 106(12): 3831-3838.
  1. 11.   Inhibition of pathological retinal neovascularization by alpha-defensins
  2. Chavakis, T.; Bdeir, K.; Cines, D. B.; Fogt, F.; Bdeir, Y.; Lubkowski, J.; Preissner, K. T.; Hammes, H. P.; Economopoulou, M.
  3. Blood. 2005, NOV 16; 106(11, Part 1): 1024A, Abstract 3678-1024A, Abstract 3678.
  1. 12.   Human beta-defensins suppress human immunodeficiency virus infection: Potential role in mucosal protection
  2. Sun, L. L.; Finnegan, C. M.; Kish-Catalone, T.; Blumenthal, R.; Garzino-Demo, P.; Maggiore, G. M. L.; Berrone, S.; Kleinman, C.; Wu, Z. B.; Abdelwahab, S.; Lu, W. Y.; Garzino-Demo, A.
  3. Journal of Virology. 2005, NOV; 79(22): 14318-14329.
  1. 13.   Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids
  2. Xie, C.; Prahl, A.; Ericksen, B.; Wu, Z. B.; Zeng, P. Y.; Li, X. Q.; Lu, W. Y.; Lubkowski, J.; Lu, W. Y.
  3. Journal of Biological Chemistry. 2005, SEP 23; 280(38): 32921-32929.
  1. 14.   Human neutrophil alpha-defensin 4 inhibits HIV-1 infection in vitro
  2. Wu, Z. B.; Cocchi, F.; Gentles, D.; Ericksen, B.; Lubkowski, J.; DeVico, A.; Lehrer, R. I.; Lu, W. Y.
  3. Febs Letters. 2005, JAN 3; 579(1): 162-166.
  1. 15.   Antimicrobial characterization of human beta-defensin 3 derivatives
  2. Hoover, D. M.; Wu, Z. B.; Tucker, K.; Lu, W. Y.; Lubkowski, J.
  3. Antimicrobial Agents and Chemotherapy. 2003 47(9): 2804-2809.
  1. 16.   Crystal structure of a cyclic form of bovine pancreatic trypsin inhibitor
  2. Botos, I.; Wu, Z. B.; Lu, W. Y.; Wlodawer, A.
  3. Febs Letters. 2001 509(1): 90-94.
  1. 17.   The role of mammalian antimicrobial peptides and proteins in awakening of innate host defenses and adaptive immunity
  2. Yang, D.; Chertov, O.; Oppenheim, J. J.
  3. Cellular and Molecular Life Sciences. 2001 58(7): 978-989.
  1. 18.   Participation of mammalian defensins and cathelicidins in anti- microbial immunity: receptors and activities of human defensins and cathelicidin (LL-37)
  2. Yang, D.; Chertov, O.; Oppenheim, J. J.
  3. Journal of Leukocyte Biology. 2001 69(5): 691-697.
  1. 19.   Human neutrophil defensins selectively chemoattract naive T and immature dendritic cells
  2. Yang, D.; Chen, Q.; Chertov, O.; Oppenheim, J. J.
  3. Journal of Leukocyte Biology. 2000 68(1): 9-14.
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