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  1. 1.   Isolation and structure elucidation of Dm-CVNH, a new cyanovirin-N homolog with activity against SARS-CoV-2 and HIV-1
  2. Orfanoudaki,Maria; Krumpe,Lauren; Shenoy, Shilpa R; Wilson,Jennifer; Guszczynski, Tad; Henrich,Curtis; Temme,Joel; Gildersleeve,Jeffrey; Molina-Molina, Elisa; Erkizia, Itziar; Blanco, Julià; Izquierdo-Useros, Nuria; Montiero, Fabio; Tanuri, Amilcar; Rech, Elibio; O'Keefe,Barry
  3. The Journal of Biological Chemistry. 2025, Feb 14; 108319.
  1. 2.   SARS-CoV-2 RNA and nucleocapsid antigen are blood biomarkers associated with severe disease outcomes that improve in response to remdesivir
  2. Singh, Kanal; Rubenstein,Kevin; Callier,Viviane; Shaw-Saliba, Katy; Rupert,Adam; Dewar,Robin; Laverdure,Sylvain; Highbarger,Helene; Lallemand,Perrine; Huang, Meei-Li; Jerome, Keith R; Sampoleo, Reigran; Mills, Margaret G; Greninger, Alexander L; Juneja, Kavita; Porter, Danielle; Benson, Constance A; Dempsey, Walla; El Sahly, Hana M; Focht, Chris; Jilg, Nikolaus; Paules, Catharine I; Rapaka, Rekha R; Uyeki, Timothy M; Lane, H Clifford; Beigel, John; Dodd, Lori E
  3. The Journal of Infectious Diseases. 2024, Sep 23; 230(3): 624-634.
  1. 3.   MoMo30 Binds to SARS-CoV-2 Spike Variants and Blocks Infection by SARS-CoV-2 Pseudovirus
  2. DeBarros, Kenya; Khan, Mahfuz; Coleman, Morgan; Bond, Vincent C; Floyd, Virginia; Gbodossou, Erick; Diop, Amad; Krumpe,Lauren; O'Keefe,Barry; Powell, Michael D
  3. Viruses. 2024, Sep 07; 16(9):
  1. 4.   An approach to rapid distributed manufacturing of broad spectrum anti-viral griffithsin using cell-free systems to mitigate pandemics
  2. Borhani, Shayan G; Levine, Max Z; Krumpe,Lauren; Wilson,Jennifer; Henrich,Curtis; O'Keefe,Barry; Lo, Donald C; Sittampalam, G Sitta; Godfrey, Alexander G; Lunsford, R Dwayne; Mangalampalli, Venkata; Tao, Dingyin; LeClair, Christopher A; Thole, Aaron P; Frey, Douglas; Swartz, James; Rao, Govind
  3. New Biotechnology. 2023, Apr 11; 76: 13-22.
  1. 5.   Cyanovirin-N binds to select SARS-CoV-2 spike oligosaccharides outside of the receptor binding domain and blocks infection by SARS-CoV-2
  2. Muñoz-Basagoiti, Jordana; Monteiro, Fábio Luís Lima; Haugh Krumpe,Lauren; Armario-Najera, Victoria; Shenoy, Shilpa R; Perez-Zsolt, Daniel; Westgarth, Harrison James; Villorbina, Gemma; Bomfim, Larissa Maciel; Raïch-Regué, Dàlia; Nogueras, Lara; Henrich,Curtis; Gallemí, Marçal; Moreira, Filipe Romero Rebello; Torres, Pascual; Wilson,Jennifer; D'arc, Mirela; Marfil, Silvia; Herlinger, Alice Laschuk; Pradenas, Edwards; Higa, Luiza Mendonça; Portero-Otin, Manuel; Trinité, Benjamin; Twyman, Richard M; Capell, Teresa; Tanuri, Amilcar; Blanco, Julià; Izquierdo-Useros, Nuria; Rech, Elibio L; Christou, Paul; O'Keefe,Barry
  3. Proceedings of the National Academy of Sciences of the United States of America. 2023, Mar 07; 120(10): e2214561120.
  1. 6.   Clinical, Virologic, and Immunologic Evaluation of Symptomatic Coronavirus Disease 2019 Rebound Following Nirmatrelvir/Ritonavir Treatment
  2. Epling, Brian P; Rocco, Joseph M; Boswell, Kristin L; Laidlaw, Elizabeth; Galindo, Frances; Kellogg,Anela; Das, Sanchita; Roder, Allison; Ghedin, Elodie; Kreitman, Allie; Dewar,Robin; Kelly, Sophie E M; Kalish, Heather; Rehman, Tauseef; Highbarger,Jeroen; Rupert,Adam; Kocher, Gregory; Holbrook, Michael R; Lisco, Andrea; Manion, Maura; Koup, Richard A; Sereti, Irini
  3. Clinical Infectious Diseases : an official publication of the Infectious Diseases Society of America. 2022, Oct 06;
  1. 7.   Physicochemical characterization of the recombinant lectin scytovirin and microbicidal activity of the SD1 domain produced in rice against HIV-1
  2. Armario-Najera, Victoria; Blanco-Perera, Amaya; Shenoy, Shilpa R; Sun, Yi; Marfil, Silvia; Muñoz-Basagoiti, Jordana; Perez-Zsolt, Daniel; Blanco, Julià; Izquierdo-Useros, Nuria; Capell, Teresa; O'Keefe,Barry; Christou, Paul
  3. Plant Cell Reports. 2022, Feb 18;
  1. 8.   Lessons in self-defence: inhibition of virus entry by intrinsic immunity
  2. Majdoul,Saliha; Compton,Alex
  3. Nature Reviews Immunology. 2021, Oct 13;
  1. 9.   Integrase Strand Transfer Inhibitors Are Effective Anti-HIV Drugs
  2. Smith, Steven J.; Zhao,Xue Zhi; Passos, Dario Oliveira; Lyumkis, Dmitry; Burke,Terrence; Hughes,Stephen
  3. Viruses (Basel). 2021, Jan 29; 13(2):
  1. 10.   Development of a Cell-Based Luciferase Complementation Assay for Identification of SARS-CoV-2 3CL(pro) Inhibitors
  2. Rawson, Jonathan M. O.; Duchon, Alice; Nikolaitchik, Olga A.; Pathak, Vinay K.; Hu, Wei-Shau
  3. Viruses. 2021, Jan 24; 13(2):
  1. 11.   PSGL-1 Inhibits the Incorporation of SARS-CoV and SARS-CoV-2 Spike Glycoproteins into Pseudovirions and Impairs Pseudovirus Attachment and Infectivity
  2. He, Sijia; Waheed, Abdul A.; Hetrick, Brian; Dabbagh, Deemah; Akhrymuk, Ivan V.; Kehn-Hall, Kylene; Freed, Eric O.; Wu, Yuntao
  3. Viruses. 2020, Dec 30; 13(1):
  1. 12.   Hantavirus Infection Is Inhibited by Griffithsin in Cell Culture
  2. Shrivastava-Ranjan, Punya; Lo, Michael K.; Chatterjee, Payel; Flint, Mike; Nichol, Stuart T.; Montgomery, Joel M.; O'Keefe,Barry; Spiropoulou, Christina F.
  3. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2020, NOV 4; 10: 561502.
  1. 13.   Griffithsin Inhibits Nipah Virus Entry and Fusion and Can Protect Syrian Golden Hamsters From Lethal Nipah Virus Challenge
  2. Lo, Michael K; Spengler, Jessica R; Haugh Krumpe,Lauren; Welch, Stephen R; Chattopadhyay, Anasuya; Harmon, Jessica R; Coleman-McCray, Joann D; Scholte, Florine E M; Hotard, Anne L; Fuqua, Joshua L; Rose, John K; Nichol, Stuart T; Palmer, Kenneth E; O'Keefe,Barry; Spiropoulou, Christina F
  3. The Journal of infectious diseases. 2020, MAY 1; 221(Supp. 4): S480-S492.
  1. 14.   Synthesis and biological evaluation of a series of 2-(((5-akly/aryl-1H-pyrazol-3-yl)methyl)thio)-5-alkyl-6-(cyclohexylmethyl)-pyrimidin-4(3H)-ones as potential HIV-1 inhibitors
  2. Wu, Yumeng; Tang, Chengrun; Rui, Ruomei; Yang, Liumeng; Ding, Wei; Wang, Jiangyuan; Li, Yiming; Lai,Christopher; Wang, Yueping; Luo, Ronghua; Xiao, Weilie; Zhang, Hongbing; Zheng, Yongtang; He, Yanping
  3. Acta pharmaceutica Sinica. B. 2020, Mar; 10(3): 512-528.
  1. 15.   Meeting report: Fourth Summer School on Innovative Approaches for Identification of Antiviral Agents (IAAASS)
  2. Le Grice,Stuart; Maccioni, Elias; Corona, Angela; Parolin, Cristina; Tramontano, Enzo
  3. Antiviral research. 2019, Feb; 162: 110-117.
  1. 16.   Safety, Tolerability, and Pharmacokinetics of Radavirsen (AVI-7100), an Antisense Oligonucleotide Targeting Influenza A M1/M2 translation.
  2. Beigel, John; Voell, Jocelyn; Muñoz, Paula; Kumar, Parag; Brooks, Kristina M; Zhang, Jianbo; Iversen, Patrick; Heald, Alison; Wong, Michael; Davey, Richard T
  3. British journal of clinical pharmacology. 2017, Sep 20;
  1. 17.   Meeting report: Third Summer School on Innovative Approaches for Identification of Antiviral Agents (IAAASS)
  2. Legrice, Stuart; Sztuba-Solinska, Joanna; Maccioni, Elias; Purzycka, Katarzyna J; Parolin, Cristina; Tramontano, Enzo
  3. Antiviral research. 2017, Mar; 139: 13-17.
  1. 18.   Antiviral proteins from natural products extracts: from discovery to the clinic
  2. O'Keefe, Barry
  3. Planta Medica. 2016, Dec; 82(Supplement 1): Abstract pl5.
  1. 19.   A Triazinone Derivative Inhibits HIV-1 Replication by Interfering with Reverse Transcriptase Activity
  2. Urano, E.; Miyauchi, K.; Kojima, Y.; Hamatake, M.; Ablan, S. D.; Fudo, S.; Freed, E. O.; Hoshino, T.; Komano, J.
  3. Chemmedchem. 2016, 19-Oct; 11(20): 2320-2326.
  1. 20.   Antiviral innate immunity: editorial overview
  2. Freed, E. O.; Gale, M.
  3. Journal of Molecular Biology. 2014, 20-Mar; 426(6): 1129-32.
  1. 21.   Ionic Liquids: Neoteric Solvents for Nucleoside Chemistry
  2. Kumar, V.; Parmar, V. S.; Malhotra, S. V.
  3. Current Organic Synthesis. 2011, Dec; 8(6): 777-786.
  1. 22.   Investigation of Griffithsin's Interactions with Human Cells Confirms Its Outstanding Safety and Efficacy Profile as a Microbicide Candidate
  2. Kouokam, J. C.; Huskens, D.; Schols, D.; Johannemann, A.; Riedell, S. K.; Walter, W.; Walker, J. M.; Matoba, N.; O'Keefe, B. R.; Palmer, K. E.
  3. Plos One. 2011, Aug; 6(8):
  1. 23.   Molecular Imaging of Influenza and Other Emerging Respiratory Viral Infections
  2. Bray, M.; Lawler, J.; Paragas, J.; Jahrling, P. B.; Mollura, D. J.
  3. Journal of Infectious Diseases. 2011, May; 203(10): 1348-1359.
  1. 24.   Anti-HIV microbicide development: targeting the virus is the key
  2. O'Keefe, B. R.
  3. Future Virology. 2011, May; 6(5): 553-556.
  1. 25.   Synthesis and biological evaluation of novel dihydro-aryl/alkylsulfanyl-cyclohexylmethyl-oxopyrimidines (S-DACOs) as high active anti-HIV agents
  2. He, Y. P.; Long, J.; Zhang, S. S.; Li, C.; Lai, C. C.; Zhang, C. S.; Li, D. X.; Zhang, D. H.; Wang, H.; Cai, Q. Q.; Zheng, Y. T.
  3. Bioorganic & Medicinal Chemistry Letters. 2011, Jan; 21(2): 694-697.
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