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  1. 1.   New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Postintoxication Model
  2. Konstantinovic, Jelena; Kiris, Erkan; Kota, Krishna P.; Kugelman-Tonos, Johanny; Videnovic, Milica; Cazares, Lisa H.; Jovanovic, Natasa Terzic; Verbic, Tatjana Z.; Andjelkoyic, Boban; Duplantier, Allen J.; Bavari, Sina; Solaja, Bogdan A.
  3. Journal of Medicinal Chemistry. 2018, Feb 22; 61(4): 1595-1608.
  1. 2.   Small Molecule Inhibitors as Countermeasures for Botulinum Neurotoxin Intoxication
  2. Li, B.; Peet, N. P.; Butler, M. M.; Burnett, J. C.; Moir, D. T.; Bowlin, T. L.
  3. Molecules. 2011, Jan; 16(1): 202-220.
  1. 3.   Pharmacophore Refinement Guides the Design of Nanomolar-Range Botulinum Neurotoxin Serotype A Light Chain Inhibitors
  2. Nuss, J. E.; Dong, Y. X.; Wanner, L. M.; Ruthel, G.; Wipf, P.; Gussio, R.; Vennerstrom, J. L.; Bavari, S.; Burnett, J. C.
  3. Acs Medicinal Chemistry Letters. 2010, Oct; 1(7): 301-305.
  1. 4.   Targeting botulinum neurotoxin persistence by the ubiquitin-proteasome system
  2. Tsai, Y. C.; Maditz, R.; Kuo, C. L.; Fishman, P. S.; Shoemaker, C. B.; Oyler, G. A.; Weissman, A. M.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2010, Sep; 107(38): 16554-16559.
  1. 5.   Iterative Structure-Based Peptide-Like Inhibitor Design against the Botulinum Neurotoxin Serotype A
  2. Zuniga, J. E.; Hammill, J. T.; Drory, O.; Nuss, J. E.; Burnett, J. C.; Gussio, R.; Wipf, P.; Bavari, S.; Brunger, A. T.
  3. Plos One. 2010, Jun; 5(6): 15.
  1. 6.   Structural basis of actin recognition and arginine ADP-ribosylation by Clostridium perfringens L-toxin
  2. Tsuge, H.; Nagahama, M.; Oda, M.; Iwamoto, S.; Utsunomiya, H.; Marquez, V. E.; Katunuma, N.; Nishizawa, M.; Sakurai, J.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2008 105(21): 7399-7404.
  1. 7.   A refined pharmacophore identifies potent 4-amino-7-chloroquinoline-based inhibitors of the botulinum neurotoxin serotype a metalloprotease
  2. Burnett, J. C.; Opsenica, D.; Sriraghavan, K.; Panchal, R. G.; Ruthel, G.; Hermone, A. R.; Nguyen, T. L.; Kenny, T. A.; Lane, D. J.; McGrath, C. F.; Schmidt, J. J.; Vennerstrom, J. L.; Gussio, R.; Solaja, B. A.; Bavari, S.
  3. Journal of Medicinal Chemistry. 2007, May; 50(9): 2127-2136.
  1. 8.   Primary cultures of embryonic chicken neurons for sensitive cell-based assay of botulinum neurotoxin: Implications for therapeutic discovery
  2. Stahl, A. M.; Ruthel, G.; Torres-Melendez, E.; Kenny, T. A.; Panchal, R. G.; Bavari, S.
  3. Journal of Biomolecular Screening. 2007, Apr; 12(3): 370-377.
  1. 9.   Multiagent vaccines vectored by Venezuelan equine encephalitis virus replicon elicits immune responses to Marburg virus and protection against anthrax and botulinum neurotoxin in mice
  2. Lee, J. S.; Groebner, J. L.; Hadjipanayis, A. G.; Negley, D. L.; Schmaljohn, A. L.; Welkos, S. L.; Smith, L. A.; Smith, J. F.
  3. Vaccine. 2006, Nov; 24(47-48): 6886-6892.
  1. 10.   Recombinant C fragment of botulinum neurotoxin B serotype (rBoNTB (H-C)) immune response and protection in the rhesus monkey
  2. Boles, J.; West, M.; Montgomery, V.; Tammariello, R.; Pitt, M. L. M.; Gibbs, P.; Smith, L.; LeClaire, R. D.
  3. Toxicon. 2006, Jun; 47(8): 877-884.
  1. 11.   Expression, purification, and characterization of Clostridium botulinum type B light chain
  2. Gilsdorf, J.; Gul, N.; Smith, L. A.
  3. Protein Expression and Purification. 2006, Apr; 46(2): 256-267.
  1. 12.   Purification and scale-up of a recombinant heavy chain fragment C of botulinum neurotoxin serotype E in Pichia pastoris GS115
  2. Dux, M. P.; Barent, R.; Sinha, J.; Gouthro, M.; Swanson, T.; Barthuli, A.; Inan, M.; Ross, J. T.; Smith, L. A.; Smith, T. J.; Webb, R.; Loveless, B.; Henderson, I.; Meagher, M. M.
  3. Protein Expression and Purification. 2006, Feb; 45(2): 359-367.
  1. 13.   The evolving field of biodefence: Therapeutic developments and diagnostics
  2. Burnett, J. C.; Henchal, E. A.; Schmaljohn, A. L.; Bavari, S.
  3. Nature Reviews Drug Discovery. 2005 4(4): 281-297.
  1. 14.   Novel small molecule inhibitors of botulinum neurotoxin A metalloprotease activity
  2. Burnett, J. C.; Schmidt, J. J.; Stafford, R. G.; Panchal, R. G.; Nguyen, T. L.; Hermone, A. R.; Vennerstrom, J. L.; McGrath, C. F.; Lane, D. J.; Sausville, E. A.; Zaharevitz, D. W.; Gussio, R.; Bavari, S.
  3. Biochemical and Biophysical Research Communications. 2003 310(1): 84-93.
  1. 15.   Substrate binding and catalysis of Ecto-ADP-ribosyltransferase 2.2 from rat
  2. Ritter, H.; Koch-Nolte, F.; Marquez, V. E.; Schulz, G. E.
  3. Biochemistry. 2003 42(34): 10155-10162.
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