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  1. 1.   Discovery of potent and selective PROTACs for the protein kinase LZK for the treatment of head and neck cancer
  2. Katerji,Meghri; Bergman, Knickole L; Lindberg, Eric; Rubin,Maxine; Funk, Amy L; Woodroofe, Carolyn C; Nyswaner, Katherine; Karpinska, Kamila; Serwa, Remigiusz; Marusiak, Anna; Swenson, Rolf E; Brognard,John
  3. The Journal of Biological Chemistry. 2025, Mar 27; 108452.
  1. 2.   Expanded profiling of WD repeat domain 5 inhibitors reveals actionable strategies for the treatment of hematologic malignancies
  2. Meyer, Christian T; Smith, Brianna N; Wang, Jing; Teuscher, Kevin B; Grieb, Brian C; Howard, Gregory C; Silver, Alexander J; Lorey, Shelly L; Stott,Gordon; Moore,Bill; Lee, Taekyu; Savona, Michael R; Weissmiller, April M; Liu, Qi; Quaranta, Vito; Fesik, Stephen W; Tansey, William P
  3. Proceedings of the National Academy of Sciences of the United States of America. 2024, Aug 27; 121(35): e2408889121.
  1. 3.   Tumor Suppression by Anti-Fibroblast Activation Protein Near-Infrared Photoimmunotherapy Targeting Cancer-Associated Fibroblasts
  2. Glabman, Raisa A; Olkowski, Colleen P; Minor, Hannah A; Bassel,Laura; Kedei, Noemi; Choyke, Peter L; Sato, Noriko
  3. Cancers. 2024, Jan 20; 16(2):
  1. 4.   Regression and Eradication of Triple-Negative Breast Carcinoma in 4T1 Mouse Model by Combination Immunotherapies
  2. Nahar,Saifun; Huang,Yue; Nagy,Bethany; Zebala, John A; Maeda, Dean Y; Rudloff, Udo; Oppenheim, Joost J; Yang,De
  3. Cancers. 2023, Apr 19; 15(8):
  1. 5.   Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models
  2. Teuscher, Kevin B; Chowdhury, Somenath; Meyers, Kenneth M; Tian, Jianhua; Sai, Jiqing; Van Meveren, Mayme; South, Taylor M; Sensintaffar, John L; Rietz, Tyson A; Goswami, Soumita; Wang, Jing; Grieb, Brian C; Lorey, Shelly L; Howard, Gregory C; Liu, Qi; Moore,Bill; Stott,Gordon; Tansey, William P; Lee, Taekyu; Fesik, Stephen W
  3. Proceedings of the National Academy of Sciences of the United States of America. 2023, Jan 03; 120(1): e2211297120.
  1. 6.   Nanocomplexes of doxorubicin and DNA fragments for efficient and safe cancer chemotherapy
  2. Mohammad, Saad N; Choi, Yeon Su; Chung, Jee Young; Cedrone,Edward; Neun,Barry; Dobrovolskaia,Marina; Yang, Xiaojing; Guo, Wei; Chew, Yap Ching; Kim, Juwan; Baek, Seunggul; Kim, Ik Soo; Fruman, David A; Kwon, Young Jik
  3. Journal of Controlled Release : official journal of the Controlled Release Society. 2023, Jan; 354: 91-108.
  1. 8.   Molecular Features of Cancers Exhibiting Exceptional Responses to Treatment
  2. Wheeler, David A; Takebe, Naoko; Hinoue, Toshinori; Hoadley, Katherine A; Cardenas, Maria F; Hamilton, Alina M; Laird, Peter W; Wang, Linghua; Johnson, Adrienne; Dewal, Ninad; Miller, Vincent; Piñeyro, David; Castro de Moura, Manuel; Esteller, Manel; Shen, Hui; Zenklusen, Jean Claude; Tarnuzzer, Roy; McShane, Lisa M; Tricoli, James V; Williams, Paul M; Lubensky, Irina; O'Sullivan-Coyne, Geraldine; Kohn, Elise C; Little, Richard F; White, Jeffrey; Malik, Shakun; Harris, Lyndsay; Weil, Carol; Chen, Alice P; Karlovich,Chris; Rodgers, Brian; Shankar, Lalitha; Jacobs, Paula; Nolan, Tracy; Hu, Jianhong; Muzny, Donna M; Doddapaneni, Harshavardhan; Korchina, Viktoriya; Gastier-Foster, Julie; Bowen, Jay; Leraas, Kristen; Edmondson,Elijah; Doroshow, James H; Conley, Barbara A; Ivy, S Percy; Staudt, Louis M
  3. Cancer Cell. 2021, Jan 11; 39(1): 38-53.e7.
  1. 9.   Gene expression signatures: A tool for analysis of breast cancer prognosis and therapy
  2. Latha, Neetha Rajan; Rajan, Arathi; Nadhan, Revathy; Achyutuni, Sarada; Sengodan,Satheesh; Hemalatha, Sreelatha Krishnakumar; Varghese, Geetu Rose; Thankappan, Ratheeshkumar; Krishnan, Neethu; Patra, Dipyaman; Warrier, Arathy; Srinivas, Priya
  3. Critical reviews in oncology/hematology. 2020, JUL; 151
  1. 10.   Targeting the RNA Polymerase I Transcription for Cancer Therapy Comes of Age
  2. Ferreira, Rita; Schneekloth,Jay; Panov, Konstantin I.; Hannan, Katherine M.; Hannan, Ross D.
  3. Cells. 2020, FEB; 9(2):
  1. 11.   Phosphatidic acid drives mTORC1 lysosomal translocation in the absence of amino acids
  2. Frias, Maria A.; Mukhopadhyay,Suman; Lehman, Elyssa; Walasek, Aleksandra; Utter, Matthew; Menon, Deepak; Foster, David A.
  3. JOURNAL OF BIOLOGICAL CHEMISTRY. 2020, JAN 3; 295(1): 263-274.
  1. 12.   Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens
  2. Clausse, Victor; Tao, Dingyin; Debnath, Subrata; Fang, Yuhong; Tagad, Harichandra D; Wang, Yuhong; Sun, Hongmao; LeClair, Christopher A; Mazur, Sharlyn J; Lane, Kelly; Shi, Zhen-Dan; Vasalatiy, Olga; Eells, Rebecca; Baker, Lynn K; Henderson, Mark J; Webb, Martin R; Shen, Min; Hall, Matthew D; Appella, Ettore; Appella, Daniel H; Coussens,Nathan
  3. The Journal of biological chemistry. 2019, Nov 15; 294(46): 17654-17668.
  1. 13.   Redox-responsive polymer inhibits macrophages uptake for effective intracellular gene delivery and enhanced cancer therapy
  2. Wen, Lijuan; Hu, Yingwen; Meng, Tingling; Tan, Yanan; Zhao, Mengdan; Dai, Suhuan; Yuan, Hong; Hu, Fuqiang
  3. Colloids and surfaces. B, Biointerfaces. 2019, Mar 1; 175: 392-402.
  1. 14.   Stable and Potent Selenomab-Drug Conjugates
  2. Li, Xiuling; Nelson, Christopher; Nair, Rajesh R; Hazlehurst, Lori; Moroni, Tina; Martinez-Acedo, Pablo; Nanna, Alex R; Hymel, David; Burke, Terrence; Rader, Christoph
  3. Cell Chemical Biology. 2017, Apr 20; 24(4): 433-442.
  1. 15.   Complexity in the signaling network: insights from the use of targeted inhibitors in cancer therapy
  2. Logue, J. S.; Morrison, D. K.
  3. Genes & Development. 2012, Apr; 26(7): 641-650.
  1. 16.   The cancer stem cell niche-there goes the neighborhood?
  2. Cabarcas, S. M.; Mathews, L. A.; Farrar, W. L.
  3. International Journal of Cancer. 2011, Nov; 129(10): 2315-2327.
  1. 17.   Light-sensitive lipid-based nanoparticles for drug delivery: design principles and future considerations for biological applications
  2. Yavlovich, A.; Smith, B.; Gupta, K.; Blumenthal, R.; Puri, A.
  3. Molecular Membrane Biology. 2010, Oct; 27(7): 364-381.
  1. 18.   Targeting hypoxia cell signaling for cancer therapy
  2. Melillo, G.
  3. Cancer and Metastasis Reviews. 2007, Jun; 26(2): 341-352.
  1. 19.   Tumor suppression and normal aging in mice with constitutively high p53 activity
  2. Mendrysa, S. M.; O'Leary, K. A.; McElwee, M. K.; Michalowski, J.; Eisenman, R. N.; Powell, D. A.; Perry, M. E.
  3. Genes & Development. 2006, JAN 1; 20(1): 16-21.
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