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  1. 1.   The lectins griffithsin, cyanovirin-N and scytovirin inhibit HIV-1 binding to the DC-SIGN receptor and transfer to CD4(+) cells
  2. Alexandre, K. B.; Gray, E. S.; Mufhandu, H.; McMahon, J. B.; Chakauya, E.; O'Keefe, B. R.; Chikwamba, R.; Morris, L.
  3. Virology. 2012, Feb; 423(2): 175-186.
  1. 2.   Topology of the disulfide bonds in the antiviral lectin scytovirin
  2. Moulaei, T.; Stuchlik, O.; Reed, M.; Yuan, W. R.; Pohl, J.; Lu, W. Y.; Haugh-Krumpe, L.; O'Keefe, B. R.; Wlodawer, A.
  3. Protein Science. 2010, Sep; 19(9): 1649-1661.
  1. 3.   Mannose-rich glycosylation patterns on HIV-1 subtype C gp120 and sensitivity to the lectins, Griffithsin, Cyanovirin-N and Scytovirin
  2. Alexandre, K. B.; Gray, E. S.; Lambson, B. E.; Moore, P. L.; Choge, I. A.; Mlisana, K.; Karim, S. S. A.; McMahon, J.; O'Keefe, B.; Chikwamba, R.; Morris, L.
  3. Virology. 2010, Jun; 402(1): 187-196.
  1. 4.   Atomic-resolution crystal structure of the antiviral lectin scytovirin
  2. Moulaei, T.; Botos, I.; Ziolkowska, N. E.; Bokesch, H. R.; Krumpe, L. R.; McKee, T. C.; O'Keefe, B. R.; Dauter, Z.; Wlodawer, A.
  3. Protein Science. 2007, Dec; 16(12): 2756-2760.
  1. 5.   The novel fold of scytovirin reveals a new twist for antiviral entry inhibitors
  2. McFeeters, R. L.; Xiong, C. Y.; O'Keefe, B. R.; Bokesch, H. R.; McMahon, J. B.; Ratner, D. M.; Castelli, R.; Seeberger, P. H.; Byrd, R. A.
  3. Journal of Molecular Biology. 2007, Jun; 369(2): 451-461.
  1. 6.   Marine pharmacology in 2003-2004: Anti-tumour and cytotoxic compounds
  2. Mayer, A. M. S.; Gustafson, K. R.
  3. European Journal of Cancer. 2006, Sep; 42(14): 2241-2270.
  1. 7.   Potent anti-HIV activity of scytovirin domain 1 peptide
  2. Xiong, C. Y.; O'Keefe, B. R.; Byrd, R. A.; McMahon, J. B.
  3. Peptides. 2006, Jul; 27(7): 1668-1675.
  1. 8.   Overexpression and purification of scytovirin, a potent, novel anti-HIV protein from the cultured cyanobacterium Scytonema varium
  2. Xiong, C. Y.; O'Keefe, B. R.; Botos, I.; Wlodawer, A.; McMahon, J. B.
  3. Protein Expression and Purification. 2006, Apr; 46(2): 233-239.
  1. 9.   Structural studies of algal lectins with anti-HIV activity
  2. Ziolkowska, N. E.; Wlodawer, A.
  3. Acta Biochimica Polonica. 2006 53(4): 617-626.
  1. 10.   Isolation and characterization of griffithsin, a novel HIV-inactivating protein, from the red alga Griffithsia sp
  2. Mori, T.; O'Keefe, B. R.; Sowder, R. C.; Bringans, S.; Gardella, R.; Berg, S.; Cochran, P.; Turpin, J. A.; Buckheit, R. W.; McMahon, J. B.; Boyd, M. R.
  3. Journal of Biological Chemistry. 2005, MAR 11; 280(10): 9345-9353.
  1. 11.   Marine pharmacology in 2001-2: antitumour and cytotoxic compounds
  2. Mayer, A. M. S.; Gustafson, K. R.
  3. European Journal of Cancer. 2004, DEC; 40(18): 2676-2704.
  1. 12.   Development of a fluorescent microplate assay for determining cyanovirin-N levels in plasma
  2. Bringans, S. D.; O'Keefe, B. R.; Bray, M.; Whitehouse, C. A.; Boyd, M. R.
  3. Analytical and Bioanalytical Chemistry. 2004, SEP; 380(2): 269-274.
  1. 13.   Gymnangiamide, a cytotoxic pentapeptide from the marine hydroid Gymnangium regae
  2. Milanowski, D. J.; Gustafson, K. R.; Rashid, M. A.; Pannell, L. K.; McMahon, J. B.; Boyd, M. R.
  3. Journal of Organic Chemistry. 2004 69(9): 3036-3042.
  1. 14.   Investigations of the marine flora and fauna of the Islands of Palau
  2. Faulkner, D. J.; Newman, D. J.; Cragg, G. M.
  3. Natural Product Reports. 2004 21(1): 50-76.
  1. 15.   Marine pharmacology in 2000: Antitumor and cytotoxic compounds
  2. Mayer, A. M. S.; Gustafson, K. R.
  3. International Journal of Cancer. 2003 105(3): 291-299.
  1. 16.   The microbicide cyanovirin-N expressed on the surface of commensal bacterium Streptococcus gordonii captures HIV-1
  2. Giomarelli, B.; Provvedi, R.; Meacci, F.; Maggi, T.; Medaglini, D.; Pozzi, G.; Mori, T.; McMahon, J. B.; Gardella, R.; Boyd, M. R.
  3. Aids. 2002 16(10): 1351-1356.
  1. 17.   Structures of the complexes of a potent anti-HIV protein cyanovirin-N and high mannose oligosaccharides
  2. Botos, I.; O'Keefe, B. R.; Shenoy, S. R.; Cartner, L. K.; Ratner, D. M.; Seeberger, P. H.; Boyd, M. R.; Wlodawer, A.
  3. Journal of Biological Chemistry. 2002 277(37): 34336-34342.
  1. 18.   Functional homologs of cyanovirin-N amenable to mass production in prokaryotic and eukaryotic hosts
  2. Mori, T.; Barrientos, L. G.; Han, Z. Z.; Gronenborn, A. M.; Turpin, J. A.; Boyd, M. R.
  3. Protein Expression and Purification. 2002 26(1): 42-49.
  1. 19.   Discovery of a stable dimeric mutant of cyanovirin-N (CV-N) from a T7 phage-displayed CV-N mutant library
  2. Han, Z. Z.; Xiong, C. Y.; Mori, T.; Boyd, M. R.
  3. Biochemical and Biophysical Research Communications. 2002 292(4): 1036-1043.
  1. 20.   Domain-swapped structure of a mutant of cyanovirin-N
  2. Botos, I.; Mori, T.; Cartner, L. K.; Boyd, M. R.; Wlodawer, A.
  3. Biochemical and Biophysical Research Communications. 2002 294(1): 184-190.
  1. 21.   Structure and absolute stereochemistry of hectochlorin, a potent stimulator of actin assembly
  2. Marquez, B. L.; Watts, K. S.; Yokochi, A.; Roberts, M. A.; Verdier-Pinard, P.; Jimenez, J. I.; Hamel, E.; Scheuer, P. J.; Gerwick, W. H.
  3. Journal of Natural Products. 2002 65(6): 866-871.
  1. 22.   HIV-inhibitory natural products part 71 - Cyanovirin-N defines a new class of antiviral agent targeting N-linked, high-mannose glycans in an oligosaccharide-specific manner
  2. Bolmstedt, A. J.; O'Keefe, B. R.; Shenoy, S. R.; McMahon, J. B.; Boyd, M. R.
  3. Molecular Pharmacology. 2001 59(5): 949-954.
  1. 23.   Analysis of the interaction between the HIV-Inactivating protein cyanovirin-N and soluble forms of the envelope glycoproteins gp120 and gp41
  2. O'Keefe, B. R.; Shenoy, S. R.; Xie, D.; Zhang, W. T.; Muschik, J. M.; Currens, M. J.; Chaiken, I.; Boyd, M. R.
  3. Molecular Pharmacology. 2000 58(5): 982-992.
  1. 24.   Synthesis and biological evaluation of a focused mixture library of analogues of the antimitotic marine natural product curacin A
  2. Wipf, P.; Reeves, J. T.; Balachandran, R.; Giuliano, K. A.; Hamel, E.; Day, B. W.
  3. Journal of the American Chemical Society. 2000 122(39): 9391-9395.
  1. 25.   Development of a Cyanovirin-N-HIV-1 gp120 binding assay for high throughput screening of natural product extracts by time-resolved fluorescence
  2. McMahon, J. B.; Beutler, J. A.; O'Keefe, B. R.; Goodrum, C. B. B.; Myers, M. A.; Boyd, M. R.
  3. Journal of Biomolecular Screening. 2000 5(3): 169-176.
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