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  1. 1.   Distinct allosteric networks in CDK4 and CDK6 in the cell cycle and in drug resistance
  2. Zhang,Wengang; Bradburn, Devin; Heidebrink, Gretchen; Liu, Yonglan; Jang,Hyunbum; Nussinov,Ruth; Kõivomägi, Mardo
  3. Journal of Molecular Biology. 2025, Mar 31; 169121.
  1. 2.   Slower CDK4 and faster CDK2 activation in the cell cycle
  2. Zhang,Wengang; Liu,Yonglan; Jang,Hyunbum; Nussinov,Ruth
  3. Structure (London, England : 1993). 2024, Apr 23;
  1. 3.   Plant Natural Products in Anticancer Drug Discovery
  2. Grothaus, P. G.; Cragg, G. M.; Newman, D. J.
  3. Current Organic Chemistry. 2010, Oct; 14(16): 1781-1791.
  1. 4.   A dual role of Cdk2 in DNA damage response
  2. Satyanarayana, A.; Kaldis, P.
  3. Cell Division. 2009, May; 4: 4.
  1. 5.   Rb/Cdk2/Cdk4 triple mutant mice elicit an alternative mechanism for regulation of the G(1)/S transition
  2. Li, W.; Kotoshiba, S.; Berthet, C.; Hilton, M. B.; Kaldis, P.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2009 106(2): 486-491.
  1. 6.   Id1 immortalizes hematopoietic progenitors in vitro and promotes a myeloproliferative disease in vivo
  2. Suh, H. C.; Leeanansaksiri, W.; Ji, M.; Klarmann, K. D.; Renn, K.; Gooya, J.; Smith, D.; McNiece, I.; Lugthart, S.; Valk, P. J.; Delwel, R.; Keller, J. R.
  3. Oncogene. 2008, Sep 18; 27(42): 5612-5623.
  1. 7.   Genetic substitution of Cdk1 by Cdk2 leads to embryonic lethality and loss of meiotic function of Cdk2
  2. Satyanarayana, A.; Berthet, C.; Lopez-Molina, J.; Coppola, V.; Tessarollo, L.; Kaldis, P.
  3. Development. 2008 135(20): 3389-3400.
  1. 8.   p21 inhibits Cdk1 in the absence of Cdk2 to maintain the G1/S phase DNA damage checkpoint
  2. Satyanarayana, A.; Hilton, M. B.; Kaldis, P.
  3. Molecular Biology of the Cell. 2008 19(1): 65-77.
  1. 9.   Cell-specific responses to loss of cyclin-dependent kinases
  2. Berthet, C.; Kaldis, P.
  3. Oncogene. 2007, Jul; 26(31): 4469-4477.
  1. 10.   Natural products from marine invertebrates and microbes as modulators of antitumor targets
  2. Newman, D. J.; Cragg, G. M.
  3. Current Drug Targets. 2006, MAR; 7(3): 279-304.
  1. 11.   Cell cycle sibling rivalry - Cdc2 vs. Cdk2
  2. Kaldis, P.; Aleem, E.
  3. Cell Cycle. 2005, NOV; 4(11): 1491-1494.
  1. 12.   Cytokine-driven cell cycling is mediated through Cdc25A
  2. Khaled, A. R.; Bulavin, D. V.; Kittipatarin, C.; Li, W. Q.; Alvarez, M.; Kim, K.; Young, H. A.; Fornace, A. J.; Durum, S. K.
  3. Journal of Cell Biology. 2005, JUN 6; 169(5): 755-763.
  1. 13.   Homology model of the CDK1/cyclin B complex
  2. McGrath, C. F.; Pattabiraman, N.; Kellogg, G. E.; Lemcke, T.; Kunick, C.; Sausville, E. A.; Zaharevitz, D. W.; Gussio, R.
  3. Journal of Biomolecular Structure & Dynamics. 2005, APR; 22(5): 493-502.
  1. 14.   The search for novel drug leads for predominately antitumor therapies by utilizing mother nature's pharmacophoric libraries
  2. Kingston, D. G. I.; Newman, D. J.
  3. Current Opinion in Drug Discovery & Development. 2005, MAR; 8(2): 207-227.
  1. 15.   Human immunodeficiency virus type 1-induced macrophage gene expression includes the p21 gene, a target for viral regulation
  2. Vazquez, N.; Greenwell-Wild, T.; Marinos, N. J.; Swaim, W. D.; Nares, S.; Ott, D. E.; Schubert, U.; Henklein, P.; Orenstein, J. M.; Sporn, M. B.; Wahl, S. M.
  3. Journal of Virology. 2005 79(7): 4479-4491.
  1. 16.   Effect of cell cycle inhibition on cisplatin-induced cytotoxicity
  2. Fishel, M. L.; Newell, D. R.; Griffin, R. J.; Davison, R.; Wang, L. Z.; Curtin, N. J.; Zuhowski, E. G.; Kasza, K.; Egorin, M. J.; Moschel, R. C.; Dolan, M. E.
  3. Journal of Pharmacology and Experimental Therapeutics. 2005, JAN; 312(1): 206-213.
  1. 17.   Induction of apoptosis by flavopiridol in human neuroblastoma cells is enhanced under hypoxia and associated with N-myc proto-oncogene down-regulation
  2. Puppo, M.; Pastorino, S.; Melillo, G.; Pezzolo, A.; Varesio, L.; Bosco, M. C.
  3. Clinical Cancer Research. 2004, DEC 15; 10(24): 8704-8719.
  1. 18.   Cdk2 knockout mice are viable
  2. Berthet, C.; Aleem, E.; Coppola, V.; Tessarollo, L.; Kaldis, P.
  3. Current Biology. 2003 13(20): 1775-1785.
  1. 19.   Rarity of CDK4 germline mutations in familial melanoma
  2. Goldstein, A. M.; Chidambaram, A.; Halpern, A.; Holly, E. A.; Guerry, D.; Sagebiel, R.; Elder, D. E.; Tucker, M. A.
  3. Melanoma Research. 2002 12(1): 51-55.
  1. 20.   Mother nature's combinatorial libraries; their influence on the synthesis of drugs
  2. Kingston, D. G. I.; Newman, D. J.
  3. Current Opinion in Drug Discovery & Development. 2002 5(2): 304-316.
  1. 21.   The effects of changing the site of activating phosphorylation in CDK2 from threonine to serine
  2. Kaldis, P.; Cheng, A. Y.; Solomon, M. J.
  3. Journal of Biological Chemistry. 2000 275(42): 32578-32584.
  1. 22.   Structure-based design modifications of the paullone molecular scaffold for cyclin-dependent kinase inhibition
  2. Gussio, R.; Zaharevitz, D. W.; McGrath, C. F.; Pattabiraman, N.; Kellogg, G. E.; Schultz, C.; Link, A.; Kunick, C.; Leost, M.; Meijer, L.; Sausville, E. A.
  3. Anti-Cancer Drug Design. 2000 15(1): 53-66.
  1. 23.   The influence of natural products upon drug discovery
  2. Newman, D. J.; Cragg, G. M.; Snader, K. M.
  3. Natural Product Reports. 2000 17(3): 215-234.
  1. 24.   Human papillomavirus and cancer: The viral transforming genes
  2. Phillips, A. C.; Vousden, K. H.; Newton, R.; Beral, V.; Weiss, R. A.
  3. Infections and Human Cancer. 1999; 33 : 55-74.
  1. 25.   Mechanisms of p53-mediated apoptosis
  2. Bates, S.; Vousden, K. H.
  3. Cellular and Molecular Life Sciences. 1999 55(1): 28-37.
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