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  1. 1.   Structural and mechanistic bases for resistance of the M66I capsid variant to lenacapavir
  2. Briganti, Lorenzo; Annamalai, Arun S; Bester, Stephanie M; Wei, Guochao; Andino-Moncada, Jonathan R; Singh, Satya P; Kleinpeter,Alexander; Tripathi, Meghna; Nguyen, Binh; Radhakrishnan, Rajalingam; Singh, Parmit K; Greenwood, Juliet; Schope, Lauren I; Haney, Reed; Huang, Szu-Wei; Freed, Eric O; Engelman, Alan N; Francis, Ashwanth C; Kvaratskhelia, Mamuka
  3. mBio. 2025, Apr 15; e0361324.
  1. 2.   Structural and virologic mechanism of the emergence of resistance to Mpro inhibitors in SARS-CoV-2
  2. Hattori, Shin-Ichiro; Bulut, Haydar; Hayashi, Hironori; Kishimoto, Naoki; Takamune, Nobutoki; Hasegawa, Kazuya; Furusawa, Yuri; Yamayoshi, Seiya; Murayama, Kazutaka; Tamamura, Hirokazu; Li,Mi; Wlodawer, Alexander; Kawaoka, Yoshihiro; Misumi, Shogo; Mitsuya, Hiroaki
  3. Proceedings of the National Academy of Sciences of the United States of America. 2024, Sep 10; 121(37): e2404175121.
  1. 3.   Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood-brain barrier
  2. Thomas, Joanna R; Frye, William J E; Robey, Robert W; Warner,Andrew; Butcher,Donna; Matta,Jennifer; Morgan,Tamara; Edmondson,Elijah; Salazar, Paula B; Ambudkar, Suresh V; Gottesman, Michael M
  3. Fluids and Barriers of the CNS. 2024, Mar 15; 21(1): 27.
  1. 4.   Rilotumumab Resistance Acquired by Intracrine Hepatocyte Growth Factor Signaling
  2. Cecchi, Fabiola; Rex, Karen; Schmidt, Joanna; Vocke, Cathy D; Lee, Young H; Burkett, Sandra; Baker, Daniel; Damore, Michael A; Coxon, Angela; Burgess, Teresa L; Bottaro, Donald P
  3. Cancers. 2023, Jan 11; 15(2):
  1. 5.   Insights into HIV-1 Transmission Dynamics Using Routinely Collected Data in the Mid-Atlantic United States
  2. Kassaye, Seble G; Grossman, Zehava; Vengurlekar, Priyanka; Chai, William; Wallace, Megan; Rhee, Soo-Yon; Meyer, William A; Kaufman, Harvey W; Castel, Amanda; Jordan, Jeanne; Crandall, Keith A; Kang, Alisa; Kumar, Princy; Katzenstein, David A; Shafer, Robert W; Maldarelli,Frank
  3. Viruses. 2022, Dec 25; 15(1):
  1. 6.   Cefiderocol and the Need for Higher-Quality Evidence: Methods Matter for Patients
  2. Epling, Brian P; Powers,John
  3. Antimicrobial Agents and Chemotherapy. 2022, Jul 18; e0076622.
  1. 7.   Cryo-EM structure and resistance landscape of M. tuberculosis MmpL3: An emergent therapeutic target
  2. Adams, Oliver; Deme,Justin; Parker, Joanne L; Fowler, Philip W; Lea,Susan; Newstead, Simon
  3. Structure (London, England : 1993). 2021, Oct 7; 29(10): 1182-1191.
  1. 8.   Drugging multiple same-allele driver mutations in cancer
  2. Nussinov,Ruth; Zhang,Mingzhen; Maloney,Ryan; Jang, Hyunbum
  3. Expert Opinion on Drug Discovery. 2021, Aug; 16(8): 823-828.
  1. 9.   Integrase Strand Transfer Inhibitors Are Effective Anti-HIV Drugs
  2. Smith, Steven J.; Zhao,Xue Zhi; Passos, Dario Oliveira; Lyumkis, Dmitry; Burke,Terrence; Hughes,Stephen
  3. Viruses (Basel). 2021, Jan 29; 13(2):
  1. 10.   Novel Opportunity to Reverse Antibiotic Resistance: To Explore Traditional Chinese Medicine With Potential Activity Against Antibiotics-Resistance Bacteria
  2. Su, Ting; Qiu, Ye; Hua, Xuesi; Ye, Bi; Luo, Haoming; Liu, Da; Qu, Peng; Qiu, Zhidong
  3. Frontiers in microbiology. 2020, DEC 22; 11
  1. 11.   Structure-Based Non-Nucleoside Inhibitor Design: Developing Inhibitors that Are Effective Against Resistant Mutants
  2. Smith,Steven; Pauly,Gary; Hewlett, Katharine; Schneider,Joel; Hughes,Stephen
  3. Chemical biology & drug design. 2020, SEP 17;
  1. 12.   HIV-1 Integrase Inhibitors that are active against Drug-Resistant Integrase Mutants
  2. Smith,Steven; Zhao,Xue Zhi; Passos, Dario Oliveira; Lyumkis, Dmitry; Burke,Terrence; Hughes,Stephen
  3. Antimicrobial agents and chemotherapy. 2020, SEP; 64(9):
  1. 13.   Long-acting rilpivirine (RPV LA) pre-exposure prophylaxis does not inhibit vaginal transmission of RPV-resistant HIV-1 nor select for high frequency drug resistance in humanized mice
  2. Melody, Kevin; Roy, Chandra N; Kline, Christopher; Cottrell, Mackenzie L; Evans, Dwayne; Shutt, Kathleen; Pennings, Pleuni S; Keele,Brandon; Bility, Moses; Kashuba, Angela D M; Ambrose, Zandrea
  3. Journal of virology. 2020, APR; 94(8):
  1. 14.   8-Day Inpatient Directly Observed Therapy for ART Failure: A Tool For Preventing Unnecessary ART Changes and Optimizing Adherence Support
  2. Winchester, Nicole E; Maldarelli, Frank; Mejia,Yolanda; Dee,Nicola; Dewar,Robin; Laidlaw, Elizabeth; Kuriakose,Safia; Stoll, Pamela; Proschan, Michael; Lane, H Clifford; Pau, Alice K
  3. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2020, MAR 15; 70(6): 1222-1225.
  1. 15.   PPAR gamma Agonist Pioglitazone in Combination With Cisplatinum Arrests a Chemotherapy-resistant Osteosarcoma PDOX Model
  2. Higuchi, Takashi; Yamamoto, Jun; Sugisawa, Norihiko; Tashiro, Yoshihiko; Nishino, Hiroto; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Igarashi, Kentaro; Bouvet, Michael; Singh,Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M
  3. Cancer genomics & proteomics. 2020, Jan-Feb; 17(1): 35-40.
  1. 16.   Combination Treatment With Sorafenib and Everolimus Regresses a Doxorubicin-resistant Osteosarcoma in a PDOX Mouse Model
  2. Higuchi, Takashi; Sugisawa, Norihiko; Miyake, Kentaro; Oshiro, Hiromichi; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Igarashi, Kentaro; Kline,Zoey; Belt,Paige; Chawla, Sant P; Bouvet, Michael; Singh,Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M
  3. Anticancer research. 2019, Sep; 39(9): 4781-4786.
  1. 17.   Transmission Dynamics of HIV Subtype A in Tel Aviv, Israel: Implications for HIV Spread and Eradication
  2. Grossman,Zehava; Avidor, Boaz; Girshengoren, Shirley; Katchman, Eugene; Maldarelli,Frank; Turner, Dan
  3. Open forum infectious diseases. 2019, Jul; 6(7): pii: ofz304..
  1. 18.   Heterogeneity in refractory acute myeloid leukemia
  2. Horibata, Sachi; Gui, Gege; Lack,Justin; DeStefano, Christin B; Gottesman, Michael M; Hourigan, Christopher S
  3. Proceedings of the National Academy of Sciences of the United States of America. 2019, MAY 21; 116(21): 10494-10503.
  1. 19.   Mutations in the HIV-1 envelope glycoprotein can broadly rescue blocks at multiple steps in the virus replication cycle
  2. Van Duyne, Rachel; Kuo, Lillian S; Pham,Phuong; Fujii, Ken; Freed,Eric
  3. Proceedings of the National Academy of Sciences of the United States of America. 2019, Apr 30; 116(18): 9040-9049.
  1. 20.   Decreased antibiotic susceptibility driven by global remodeling of the Klebsiella pneumoniae proteome
  2. Keasey, Sarah L; Suh, Moo-Jin; Das, Sudipto; Blancett, Candace D; Zeng, Xiankun; Andresson, Thorkell; Sun, Mei G; Ulrich, Robert G
  3. Molecular & cellular proteomics : MCP. 2019, Apr; 18(4): 657-668.
  1. 21.   Tumor suppressor RARRES1 links tubulin deglutamylation to mitochondrial metabolism and cell survival
  2. Maimouni, Sara; Lee, Mi-Hye; Sung, You-Me; Hall, Michael; Roy, Arpita; Ouaari, Chokri; Hwang,Yoo-Seok; Spivak, Justin; Glasgow, Eric; Swift, Matthew; Patel, Jay; Cheema, Amrita; Kumar, Deepak; Byers, Stephen
  3. Oncotarget. 2019, Feb 26; 10(17): 1606-1624.
  1. 22.   Cell-Free DNA Next-Generation Sequencing Prediction of Response and Resistance to Third-Generation EGFR Inhibitor
  2. Helman, Elena; Nguyen, Minh; Karlovich, Chris; Despain, Darrin; Choquette, A Karin; Spira, Alexander I; Yu, Helena A; Camidge, D Ross; Harding, Thomas C; Lanman, Richard B; Simmons, Andrew D
  3. Clinical lung cancer. 2018, Nov; 19(6): 518-530.e7.
  1. 23.   Rapid Development of High-Level Resistance to Dolutegravir With Emergence of T97A Mutation in 2 Treatment-Experienced Individuals With Baseline Partial Sensitivity to Dolutegravir
  2. George, Jomy M; Kuriakose,Safia; Dee,Nicola; Stoll, Pam; Lalani, Tahaniyat; Dewar,Robin; Khan,Muhammad; Rehman,Tauseef; Grossman,Zehava; Maldarelli,Frank; Pau, Alice K
  3. Open forum infectious diseases. 2018, Oct; 5(10): ofy221.
  1. 24.   Design, synthesis, and structure-activity relationships of pyrimido[4,5-b]indole-4-amines as microtubule depolymerizing agents that are effective against multidrug resistant cells
  2. Devambatla, Ravi Kumar Vyas; Li, Wei; Zaware, Nilesh; Choudhary, Shruti; Hamel, Ernest; Mooberry, Susan L; Gangjee, Aleem
  3. Bioorganic & Medicinal Chemistry Letters. 2017, Aug 01; 27(15): 3423-3430.
  1. 25.   Effective treatment of SIVcpz-induced immunodeficiency in a captive western chimpanzee
  2. Barbian, Hannah J; Jackson-Jewett, Raven; Brown, Corrine S; Bibollet-Ruche, Frederic; Learn, Gerald H; Decker, Timothy; Kreider, Edward F; Li, Yingying; Denny, Thomas N; Sharp, Paul M; Shaw, George M; Lifson, Jeffrey; Acosta, Edward P; Saag, Michael S; Bar, Katharine J; Hahn, Beatrice H
  3. Retrovirology. 2017, Jun 02; 14(1): 35.
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