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  1. 1.   Drug-Linker Constructs Bearing Unique Dual-Mechanism Tubulin Binding Payloads Tethered through Cleavable and Non-Cleavable Linkers
  2. Ford, Jacob W; VanNatta, Jennifer M; Mondal, Deboprosad; Lin, Chen-Ming; Deng, Yuling; Bai, Ruoli; Hamel,Ernest; Trawick, Mary Lynn; Pinney, Kevin G
  3. Tetrahedron. 2025, Feb 01; 171
  1. 2.   Naamidine A reveals a promising zinc-binding strategy for topical antifungal therapy
  2. Puumala, Emily; Nabeela, Sunna; Thornburg,Chris; Grkovic,Tanja; Uppuluri, Priya; Whitesell, Luke; O'Keefe,Barry; Robbins, Nicole; Cowen, Leah E
  3. Antimicrobial Agents and Chemotherapy. 2024, Sep 26; e0119424.
  1. 3.   DOCK 6: Incorporating hierarchical traversal through precomputed ligand conformations to enable large-scale docking
  2. Balius,Trent; Tan, Y Stanley; Chakrabarti,Mayukh
  3. Journal of Computational Chemistry. 2023, Sep 25;
  1. 4.   Peptide hydrogels for affinity-controlled release of therapeutic cargo: Current and potential strategies
  2. Nambiar,Monessha; Schneider,Joel
  3. Journal of Peptide Science. 2021, Nov 7; e3377.
  1. 5.   Structural basis of substrate specificity in human cytidine deaminase family APOBEC3s
  2. Hou, Shurong; Lee, Jeong Min; Myint,Wazo; Matsuo,Hiroshi; Yilmaz, Nese Kurt; Schiffer, Celia A.
  3. Journal of Biological Chemistry. 2021, Aug; 297(2):
  1. 6.   Bioinformatic analysis linking genomic defects to chemosensitivity and mechanism of action
  2. Covell,David
  3. PloS one. 2021, Apr 28; 16(4):
  1. 7.   Deciphering the chemical instability of sphaeropsidin A under physiological conditions - degradation studies and structural elucidation of the major metabolite
  2. van der Westhuyzen, Alet E; Ingels, Aude; Rosière, Rémi; Amighi, Karim; Oberer, Lukas; Gustafson,Kirk; Wang,Dongdong; Evidente, Antonio; Maddau, Lucia; Masi, Marco; de Villiers, André; Green, Ivan R; Berger, Walter; Kornienko, Alexander; Mathieu, Veronique; van Otterlo, Willem A L
  3. Organic & biomolecular chemistry. 2020, OCT 28; 18(40): 8147-8160.
  1. 8.   A reanalysis of nanoparticle tumor delivery using classical pharmacokinetic metrics
  2. Price, Lauren S. L.; Stern,Steve; Deal, Allison M.; Kabanov, Alexander; Zamboni, William C.
  3. SCIENCE ADVANCES. 2020, JUL; 6(29): eaay9249.
  1. 9.   Linked dual-class HIV resistance mutations are associated with treatment failure
  2. Boltz,Valerie; Shao,Wei; Bale,Michael; Halvas, Elias; Luke,Brian; McIntyre, James A.; Schooley, Robert T.; Lockman, Shahin; Currier, Judith S.; Sawe, Fred; Hogg, Evelyn; Hughes, Michael D.; Kearney,Mary; Coffin, John M.; Mellors, John W.
  3. JCI INSIGHT. 2019, OCT 3; 4(19):
  1. 10.   Inhibition of HIV Maturation via Selective Unfolding and Cross-Linking of Gag Polyprotein by a Mercaptobenzamide Acetylator
  2. Jenkins, Lisa M. Miller; Paine, Elliott L.; Deshmukh, Lalit; Nikolayevskiy, Herman; Lyons, Gaelyn C.; Scerba, Michael T.; Rosenker, Kara George; Luecke, Hans F.; Louis, John M.; Chertova,Elena; Gorelick,Robert; Ott,David; Clore, G. Marius; Appella, Daniel H.
  3. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2019, MAY 22; 141(20): 8327-8338.
  1. 11.   Blood Interactions, Pharmacokinetics, and Depth-Dependent Ablation of Rat Mammary Tumors with Photoactivatable, Liposomal Doxorubicin
  2. Carter, Kevin A.; Luo, Dandan; Geng, Jumin; Stern, Steve; Lovell, Jonathan F.
  3. Molecular cancer therapeutics. 2019, Mar; 18(3): 592-601.
  1. 12.   International Multisite Study of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Proarrhythmic Potential Assessment
  2. Blinova, Ksenia; Dang, Qianyu; Millard, Daniel; Smith, Godfrey; Pierson, Jennifer; Guo, Liang; Brock, Mathew; Lu, Hua Rong; Kraushaar, Udo; Zeng, Haoyu; Shi, Hong; Zhang, Xiaoyu; Sawada, Kohei; Osada, Tomoharu; Kanda, Yasunari; Sekino, Yuko; Pang, Li; Feaster, Tromondae K; Kettenhofen, Ralf; Stockbridge, Norman; Strauss, David G; Gintant, Gary
  3. Cell Reports. 2018, Sep 25; 24(13): 3582-3592.
  1. 13.   Deciphering the mechanism of potent peptidomimetic inhibitors targeting Plasmepsins: Biochemical and structural insights
  2. Mishra, Vandana; Rathore, Ishan; Arekar, Anagha; Sthanam, Lakshmi Kavitha; Xiao, Huogen; Kiso, Yoshiaki; Sen, Shamik; Patankar, Swati; Gustchina, Alla; Hidaka, Koushi; Wlodawer, Alexander; Yada, Rickey Y; Bhaumik, Prasenjit
  3. FEBS Journal. 2018, Aug; 285(16): 3077-3096.
  1. 14.   Patterns of Sensitivity to a Panel of Drugs are highly Individualized for Undifferentiated/Unclassified Soft Tissue Sarcoma (USTS) in Patient-Derived Orthotopic Xenograft (PDOX) Nude-Mouse Models
  2. Kawaguchi, Kei; Igarashi, Kentaro; Miyake, Kentaro; Kiyuna, Tasuku; Miyake, Masuyo; Singh, Arun S; Chmielowski, Bartosz; Nelson, Scott D; Russell, Tara A; Dry, Sarah M; Li, Yunfeng; Unno, Michiaki; Singh, Shree Ram; Eilber, Fritz C; Hoffman, Robert M
  3. Journal of drug targeting. 2018, Jul 19; 1-25.
  1. 15.   Differential Influence of the Antiretroviral Pharmacokinetic Enhancers Ritonavir and Cobicistat on Intestinal P-Glycoprotein Transport and the Pharmacokinetic/Pharmacodynamic Disposition of Dabigatran
  2. Kumar, Parag; Gordon, Lori A.; Brooks, Kristina M.; George, Jomy M.; Kellogg, Anela; McManus, Maryellen; Alfaro, Raul M.; Nghiem, Khanh; Lozier, Jay; Hadigan, Colleen; Penzak, Scott R.
  3. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2017, NOV; 61(11):
  1. 16.   Structure-Guided Optimization of HIV Integrase Strand Transfer Inhibitors
  2. Zhao, Xue Zhi; Smith, Steven; Maskell, Daniel P.; Metifiot, Mathieu; Pye, Valerie E.; Fesen, Katherine; Marchand, Christophe; Pommier, Yves; Cherepanov, Peter; Hughes, Stephen; Burke, Terrence
  3. Journal of Medicinal Chemistry. 2017, SEP 14; 60(17): 7315-7332.
  1. 17.   Antiretroviral Boosting Agent Cobicistat Increases the Pharmacokinetic Exposure and Anticoagulant Effect of Dabigatran in HIV-Negative Healthy Volunteers.
  2. Gordon, Lori A; Kumar, Parag; Brooks, Kristina M; Kellogg, Anela; McManus, Maryellen; Alfaro, Raul M; Nghiem, Khanh; George, Jomy M; Lozier, Jay; Penzak, Scott R; Hadigan, Colleen
  3. Circulation. 2016, Dec 6; 134(23): 1909-1911.
  1. 18.   Growth-inhibitory and chemosensitizing effects of the glutathione-S-transferase-p-activated nitric oxide donor PABA/NO in malignant gliomas
  2. Kogias, E.; Osterberg, N.; Baumer, B.; Psarras, N.; Koentges, C.; Papazoglou, A.; Saavedra, J. E.; Keefer, L. K.; Weyerbrock, A.
  3. International Journal of Cancer. 2012, Mar; 130(5): 1184-1194.
  1. 19.   Evolution-Based Design of an Injectable Hydrogel
  2. Geisler, I. M.; Schneider, J. P.
  3. Advanced Functional Materials. 2012, Feb; 22(3): 529-537.
  1. 20.   JS-K, a Glutathione S-Transferase-Activated Nitric Oxide Donor With Antineoplastic Activity in Malignant Gliomas
  2. Weyerbrock, A.; Osterberg, N.; Psarras, N.; Baumer, B.; Kogias, E.; Werres, A.; Bette, S.; Saavedra, J. E.; Keefer, L. K.; Papazoglou, A.
  3. Neurosurgery. 2012, Feb; 70(2): 497-510.
  1. 21.   Biochemical, inhibition and inhibitor resistance studies of xenotropic murine leukemia virus-related virus reverse transcriptase
  2. Ndongwe, T. P.; Adedeji, A. O.; Michailidis, E.; Ong, Y. T.; Hachiya, A.; March, B.; Ryan, E. M.; Rai, D. K.; Kirby, K. A.; Whatley, A. S.; Burke, D. H.; Johnson, M.; Ding, S. L.; Zheng, Y. M.; Liu, S. L.; Kodama, E. I.; Delviks-Frankenberry, K. A.; Pathak, V. K.; Mitsuya, H.; Parniak, M. A.; Singh, K.; Sarafianos, S. G.
  3. Nucleic Acids Research. 2012, Jan; 40(1): 345-359.
  1. 22.   Genotypic Resistance at Viral Rebound Among Patients Who Received Lopinavir/Ritonavir-Based or Efavirenz-Based First Antiretroviral Therapy in South Africa
  2. Dlamini, J. N.; Hu, Z. H.; Ledwaba, J.; Morris, L.; Maldarelli, F. M.; Dewar, R. L.; Highbarger, H. C.; Somaroo, H.; Sangweni, P.; Follmann, D. A.; Pau, A. K.; Phidisa, I. I. S. T.
  3. Jaids-Journal of Acquired Immune Deficiency Syndromes. 2011, Nov; 58(3): 304-308.
  1. 23.   Polymeric Lipid Assemblies as Novel Theranostic Tools
  2. Puri, A.; Blumenthal, R.
  3. Accounts of Chemical Research. 2011, Oct; 44(10): 1071-1079.
  1. 24.   Human Leukocyte Antigen Genotype and Risk of HIV Disease Progression before and after Initiation of Antiretroviral Therapy
  2. Kuniholm, M. H.; Gao, X. J.; Xue, X. N.; Kovacs, A.; Anastos, K.; Marti, D.; Greenblatt, R. M.; Cohen, M. H.; Minkoff, H.; Gange, S. J.; Fazzari, M.; Young, M. A.; Strickler, H. D.; Carrington, M.
  3. Journal of Virology. 2011, Oct; 85(20): 10826-10833.
  1. 25.   Mechanisms and Factors that Influence High Frequency Retroviral Recombination
  2. Delviks-Frankenberry, K.; Galli, A.; Nikolaitchik, O.; Mens, H.; Pathak, V. K.; Hu, W. S.
  3. Viruses-Basel. 2011, Sep; 3(9): 1650-1680.
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