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  1. 1.   The three-dimensional structure of the Vint domain from Tetrahymena thermophila suggests a ligand-regulated cleavage mechanism by the HINT fold
  2. Iwaï, Hideo; Beyer, Hannes M; Johansson, Julia E M; Li,Mi; Wlodawer,Alexander
  3. FEBS Letters. 2024, Feb 13;
  1. 2.   Sonic hedgehog is not a limb morphogen but acts as a trigger to specify all digits in mice
  2. Zhu, Jianjian; Patel,Rashmi; Trofka, Anna; Harfe, Brian D; Mackem,Susan
  3. Developmental Cell. 2022, Aug 13; 57(17): 2048-2062.
  1. 3.   Zic5 stabilizes Gli3 via a non-transcriptional mechanism during retinal development
  2. Sun,Jian; Yoon,Jaeho; Lee,Moonsup; Lee,Hyun Kyung; Hwang,Rich Yooseok; Daar,Ira
  3. Cell Reports. 2022, Feb 01; 38(5):
  1. 4.   My personal mutanome: a computational genomic medicine platform for searching network perturbing alleles linking genotype to phenotype
  2. Zhou, Yadi; Zhao, Junfei; Fang, Jiansong; Martin, William; Li, Lang; Nussinov,Ruth; Chan, Timothy A.; Eng, Charis; Cheng, Feixiong
  3. Genome Biology. 2021, Jan 29; 22(1):
  1. 5.   SAVI, in silico generation of billions of easily synthesizable compounds through expert-system type rules
  2. Patel,Hitesh; Ihlenfeldt, Wolf-Dietrich; Judson, Philip N; Moroz, Yurii S; Pevzner, Yuri; Peach,Megan; Delannee,Victorien; Tarasova,Nadya; Nicklaus,Marc
  3. Scientific data. 2020, NOV 11; 7(1): 384.
  1. 6.   Genetic and Epigenetic Regulation of the Smoothened Gene (SMO) in Cancer Cells
  2. Lou,Hong; Li,Hongchuan; Huehn, Andrew R; Tarasova,Nadya; Saleh, Bahara; Anderson, Stephen K; Dean,Michael
  3. Cancers. 2020, Aug 08; 12(8): pii: E2219.
  1. 7.   Plasmacytoid dendritic cells sense HIV replication before detectable viremia following treatment interruption
  2. Mitchell, Julie L.; Takata, Hiroshi; Muir, Roshell; Colby, Donn J.; Kroon, Eugene; Crowell, Trevor A.; Sacdalan, Carlo; Pinyakorn, Suteeraporn; Puttamaswin, Suwanna; Benjapornpong, Khunthalee; Trichavaroj, Rapee; Tressler, Randall L.; Fox, Lawrence; Polonis, Victoria R.; Bolton, Diane L.; Maldarelli,Frank; Lewin, Sharon R.; Haddad, Elias K.; Phanuphak, Praphan; Robb, Merlin L.; Michael, Nelson L.; de Souza, Mark; Phanuphak, Nittaya; Ananworanich, Jintanat; Trautmann, Lydie
  3. JOURNAL OF CLINICAL INVESTIGATION. 2020, JUN 1; 130(6): 2845-2858.
  1. 8.   Heterodimeric IL-15 delays tumor growth and promotes intratumoral CTL and dendritic cell accumulation by a cytokine network involving XCL1, IFN-?, CXCL9 and CXCL10
  2. Bergamaschi,Cristina; Pandit,Hrishikesh; Nagy,Bethany; Stellas,Dimitris; Jensen, Shawn M; Bear,Jenifer; Cam,Maggie; Valentin,Antonio; Fox, Bernard A; Felber,Barbara; Pavlakis,George
  3. Journal for immunotherapy of cancer. 2020, May; 8(1): e000599.
  1. 9.   A frizzled-like cysteine rich domain in glypican-3 mediates Wnt binding and regulates hepatocellular carcinoma tumor growth in mice
  2. Li, Na; Wei, Liwen; Liu, Xiaoyu; Bai, Hongjun; Ye, Yvonne; Li, Dan; Li, Nan; Baxa,Ulrich; Wang, Qun; Lv, Ling; Chen, Yun; Feng, Mingqian; Lee, Byungkook; Gao, Wei; Ho, Mitchell
  3. Hepatology (Baltimore, Md.). 2019, OCT; 70(4): 1231-1245.
  1. 10.   A Systems Pharmacology Approach Uncovers Wogonoside as an Angiogenesis Inhibitor of Triple-Negative Breast Cancer by Targeting Hedgehog Signaling
  2. Huang, Yujie; Fang, Jiansong; Lu, Weiqiang; Wang, Zihao; Wang, Qi; Hou, Yuan; Jiang, Xingwu; Reizes, Ofer; Lathia, Justin; Nussinov,Ruth; Eng, Charis; Cheng, Feixiong
  3. Cell chemical biology. 2019, Aug 15; 26(8): 1143-1158.e.
  1. 11.   John Saunders' ZPA, Sonic hedgehog and digit identity - How does it really all work?
  2. Zhu, Jianjian; Mackem, Susan
  3. Developmental Biology. 2017, Sep 15; 429(2 Special Issue): 391-400.
  1. 12.   In Vitro Modeling Using Ciliopathy-Patient-Derived Cells Reveals Distinct Cilia Dysfunctions Caused by CEP290 Mutations
  2. Shimada, Hiroko; Lu, Quanlong; Kettenhofen, Christine; Nagashima, Kunio; English, Milton A; Semler, Elizabeth; Mahgerefteh, Jacklyn; Cideciyan, Artur V; Li, Tiansen; Brooks, Brian P; Gunay-Aygun, Meral; Jacobson, Samuel G; Cogliati, Tiziana; Westlake, Christopher; Swaroop, Anand
  3. Cell Reports. 2017, Jul 11; 20(2): 384-396.
  1. 13.   Evolution: Enhanced Footing for Snake Limb Development
  2. Kaltcheva, Maria; Lewandoski, Mark
  3. CURRENT BIOLOGY. 2016, Dec 5; 26(23): R1237-R1240.
  1. 14.   A Randomized Controlled Trial to Evaluate the Effectiveness of a Board Game on Patients' Knowledge Uptake of HIV and Sexually Transmitted Diseases at the Infectious Diseases Institute, Kampala, Uganda
  2. Wanyama, J. N.; Castelnuovo, B.; Robertson, G.; Newell, K.; Sempa, J. B.; Kambugu, A.; Manabe, Y. C.; Colebunders, R.
  3. Jaids-Journal of Acquired Immune Deficiency Syndromes. 2012, Mar; 59(3): 253-258.
  1. 15.   Cre-mediated recombination can induce apoptosis in vivo by activating the p53 DNA damage-induced pathway
  2. Zhu, J. J.; Nguyen, M. T.; Nakamura, E.; Yang, J. M.; Mackem, S.
  3. Genesis. 2012, Feb; 50(2): 102-111.
  1. 16.   Immune suppression in the tumor microenvironment: a role for dendritic cell-mediated tolerization of T cells
  2. Hurwitz, A. A.; Watkins, S. K.
  3. Cancer Immunology Immunotherapy. 2012, Feb; 61(2): 289-293.
  1. 17.   DENDRONIZED BI-2-QUINOLINE LIGANDS AND THEIR METAL COMPLEXES: DENDRON SYNTHESIS AND METALLOASSEMBLY
  2. Patri, A.; Moorefield, C. N.; Newkome, G. R.
  3. Heterocycles. 2012, Jan; 84(2): 1023-1032.
  1. 18.   A G beta gamma Effector, ElmoE, Transduces GPCR Signaling to the Actin Network during Chemotaxis
  2. Yan, J. S.; Mihaylov, V.; Xu, X. H.; Brzostowski, J. A.; Li, H. Y.; Liu, L. H.; Veenstra, T. D.; Parent, C. A.; Jin, T.
  3. Developmental Cell. 2012, Jan; 22(1): 92-103.
  1. 19.   Contrasting effects of TNF and anti-TNF on the activation of effector T cells and regulatory T cells in autoimmunity
  2. Chen, X.; Oppenheim, J. J.
  3. Febs Letters. 2011, Dec; 585(23): 3611-3618.
  1. 20.   Copy Number Variation of KIR Genes Influences HIV-1 Control
  2. Pelak, K.; Need, A. C.; Fellay, J.; Shianna, K. V.; Feng, S.; Urban, T. J.; Ge, D. L.; De Luca, A.; Martinez-Picado, J.; Wolinsky, S. M.; Martinson, J. J.; Jamieson, B. D.; Bream, J. H.; Martin, M. P.; Borrow, P.; Letvin, N. L.; McMichael, A. J.; Haynes, B. F.; Telenti, A.; Carrington, M.; Goldstein, D. B.; Alter, G.; Vaccine, N. C. H. A.
  3. Plos Biology. 2011, Nov; 9(11):
  1. 21.   CCR6/CCR10-mediated plasmacytoid dendritic cell recruitment to inflamed epithelia after instruction in lymphoid tissues
  2. Sisirak, V.; Vey, N.; Vanbervliet, B.; Duhen, T.; Puisieux, I.; Homey, B.; Bowman, E. P.; Trinchieri, G.; Dubois, B.; Kaiserlian, D.; Lira, S. A.; Puisieux, A.; Blay, J. Y.; Caux, C.; Bendriss-Vermare, N.
  3. Blood. 2011, Nov; 118(19): 5130-5140.
  1. 22.   Awareness of Direct-to-Consumer Genetic Tests and Use of Genetic Tests Among Puerto Rican Adults, 2009
  2. Ortiz, A. P.; Lopez, M.; Flores, L. T.; Soto-Salgado, M.; Rutten, L. J. F.; Serrano-Rodriguez, R. A.; Hesse, B. W.; Tortolero-Luna, G.
  3. Preventing Chronic Disease. 2011, Sep; 8(5):
  1. 23.   Analysis of Binding of KIR3DS1*014 to HLA Suggests Distinct Evolutionary History of KIR3DS1
  2. O'Connor, G. M.; Yamada, E.; Rampersaud, A.; Thomas, R.; Carrington, M.; McVicar, D. W.
  3. Journal of Immunology. 2011, Sep; 187(5): 2162-2171.
  1. 24.   CD8 alpha(+) Dendritic Cells Are the Critical Source of Interleukin-12 that Controls Acute Infection by Toxoplasma gondii Tachyzoites
  2. Mashayekhi, M.; Sandau, M. M.; Dunay, I. R.; Frickel, E. M.; Khan, A.; Goldszmid, R. S.; Sher, A.; Ploegh, H. L.; Murphy, T. L.; Sibley, L. D.; Murphy, K. M.
  3. Immunity. 2011, Aug; 35(2): 249-259.
  1. 25.   TNF optimally activatives regulatory T cells by inducing TNF receptor superfamily members TNFR2, 4-1BB and OX40
  2. Hamano, R.; Huang, J. Q.; Yoshimura, T.; Oppenheim, J. J.; Chen, X.
  3. European Journal of Immunology. 2011, Jul; 41(7): 2010-2020.
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