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  1. 1.   Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites
  2. Buey, R. M.; Calvo, E.; Barasoain, I.; Pineda, O.; Edler, M. C.; Matesanz, R.; Cerezo, G.; Vanderwal, C. D.; Day, B. W.; Sorensen, E. J.; Lopez, J. A.; Andreu, J. M.; Hamel, E.; Diaz, J. F.
  3. Nature Chemical Biology. 2007, Feb; 3(2): 117-125.
  1. 2.   Tubulin assembly, taxoid site binding, and cellular effects of the microtubule-stabilizing agent dictyostatin
  2. Madiraju, C.; Edler, M. C.; Hamel, E.; Raccor, B. S.; Balachandran, R.; Zhu, G. Y.; Giuliano, K. A.; Vogt, A.; Shin, Y. S.; Fournier, J. H.; Fukui, Y. H.; Bruckner, A. M.; Curran, D. P.; Day, B. W.
  3. Biochemistry. 2005, NOV 15; 44(45): 15053-15063.
  1. 3.   A quantitative evaluation of the effects of inhibitors of tubulin assembly on polymerization induced by discodermolide, epothilone B, and paclitaxel
  2. Dabydeen, D. A.; Florence, G. J.; Paterson, I.; Hamel, E.
  3. Cancer Chemotherapy and Pharmacology. 2004 53(5): 397-403.
  1. 4.   Medicinals for the millennia - The historical record
  2. Cragg, G. M.; Newman, D. J.
  3. New Vistas in Therapeutics, from Drug Design to Gene Therapy: Drug-Resistant Tuberculosis, from Molecules to Macro-Economics. 2001; 953 : 3-25.
  1. 5.   Chemical synthesis and biological properties of pyridine epothilones
  2. Nicolaou, K. C.; Scarpelli, R.; Bollbuck, B.; Werschkun, B.; Pereira, M. M. A.; Wartmann, M.; Altmann, K. H.; Zaharevitz, D.; Gussio, R.; Giannakakou, P.
  3. Chemistry & Biology. 2000 7(8): 593-599.
  1. 6.   The coral-derived natural products eleutherobin and sarcodictyins A and B: Effects on the assembly of purified tubulin with and without microtubule-associated proteins and binding at the polymer taxoid site
  2. Hamel, E.; Sackett, D. L.; Vourloumis, D.; Nicolaou, K. C.
  3. Biochemistry. 1999 38(17): 5490-5498.
  1. 7.   Designed Epothilones - Combinatorial Synthesis, Tubulin Assembly Properties, and Cytotoxic Action Against Taxol-Resistant Tumor Cells
  2. Nicolaou, K. C.; Vourloumis, D.; Li, T. H.; Pastor, J.; Winssinger, N.; He, Y.; Ninkovic, S.; Sarabia, F.; Vallberg, H.; Roschangar, F.; King, N. P.; Finlay, M. R. V.; Giannakakou, P.; Verdierpinard, P.; Hamel, E.
  3. Angewandte Chemie-International Edition. 1997 36(19): 2097-2103.
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