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  1. 1.   Discovery of potent and selective PROTACs for the protein kinase LZK for the treatment of head and neck cancer
  2. Katerji,Meghri; Bergman, Knickole L; Lindberg, Eric; Rubin,Maxine; Funk, Amy L; Woodroofe, Carolyn C; Nyswaner, Katherine; Karpinska, Kamila; Serwa, Remigiusz; Marusiak, Anna; Swenson, Rolf E; Brognard,John
  3. The Journal of Biological Chemistry. 2025, Mar 27; 108452.
  1. 2.   The integrated stress response regulates 18S nonfunctional rRNA decay in mammals
  2. Coria,Aaztli; Shah,Akruti; Shafieinouri,Mohammad; Taylor, Sarah J; Orgebin,Emilien; Guiblet,Wilfried; Miller,Jennifer; Sharma, Indra Mani; Wu, Colin Chih-Chien
  3. Molecular Cell. 2025, Feb 07;
  1. 3.   Chronic Low-Level IFN-gamma Expression Disrupts Mitochondrial Complex I Activity in Renal Macrophages: An Early Mechanistic Driver of Lupus Nephritis Pathogenesis
  2. Bae, Heekyong R; Shin, Su-Kyung; Lee, Ji-Yoon; Ko, Yeo Jin; Kim, Suntae; Young,Howard; Kwon, Eun-Young
  3. International Journal of Molecular Sciences. 2024, Dec 25; 26(1):
  1. 4.   Benzyl Ammonium Carbamates Undergo Two-Step Linker Cleavage and Improve the Properties of Antibody Conjugates
  2. Li,Xiaoyi; Patel,Nimit; Kalen,Joseph; Schnermann,Martin
  3. Angewandte Chemie (International ed. in English). 2024, Dec 18; e202417651.
  1. 5.   Angiopoietin-2 reverses endothelial cell dysfunction in progeria vasculature
  2. Vakili, Sahar; Izydore, Elizabeth K; Losert, Leonhard; Cabral, Wayne A; Tavarez, Urraca L; Shores, Kevin; Xue,Huijing; Erdos, Michael R; Truskey, George A; Collins, Francis S; Cao, Kan
  3. Aging Cell. 2024, Oct 18; e14375.
  1. 6.   Genome-scale exon perturbation screens uncover exons critical for cell fitness
  2. Xiao,Meisheng; Damodaran,Arun Prasath; Kumari,Bandana; Dickson, Ethan; Xing, Kun; On, Tyler A; Parab, Nikhil; King, Helen E; Perez, Alexendar R; Guiblet,Wilfried; Duncan,Gerard; Che,Anney; Chari,Raj; Andresson,Thorkell; Vidigal, Joana A; Weatheritt, Robert J; Aregger,Michael; Gonatopoulos Pournatzis,Thomas
  3. Molecular Cell. 2024, Jul 11; 84(13): 2553-2572.
  1. 7.   Sequencing-based functional assays for classification of BRCA2 variants in mouse ESCs
  2. Biswas,Kajal; Mitrophanov,Alex; Sahu,Sounak; Sullivan,Teresa; Southon,Eileen; Nousome,Darryl; Reid, Susan; Narula, Sakshi; Smolen, Julia; Sengupta, Trisha; Riedel-Topper, Maximilian; Kapoor, Medha; Babbar, Anav; Stauffer,Stacey; Cleveland, Linda; Tandon, Mayank; Malys,Tyler; Sharan,Shyam
  3. Cell Reports Methods. 2023, Nov 20; 3(11): 100628.
  1. 8.   Highlights from the Tenth International Workshop on HIV Persistence during Therapy, December 13-16, 2022, Miami, Florida-USA
  2. Archin, N; Bar, K J; Burdo, T; Caskey, M; Chahroudi, A; Farzan, M; Ho, Y-C; Jones, R B; Kearney,Mary; Kuritzkes, D; Margolis, D; Martinez-Picado, J; Okoye, A; Salgado, M; Stevenson, Mario
  3. Journal of Virus Eradication. 2023, Mar; 9(1): 100315.
  1. 9.   Immunization of Mice with Virus-Like Vesicles of Kaposi Sarcoma-Associated Herpesvirus Reveals a Role for Antibodies Targeting ORF4 in Activating Complement-Mediated Neutralization
  2. Lam, Alex K; Roshan,Romin; Miley,Wendell; Labo, Nazzarena; Zhen, James; Kurland, Andrew P; Cheng, Celine; Huang, Haigen; Teng, Pu-Lin; Harelson, Claire; Gong, Danyang; Tam, Ying K; Radu, Caius G; Epeldegui, Marta; Johnson, Jeffrey R; Zhou, Z Hong; Whitby,Denise; Wu, Ting-Ting
  3. Journal of Virology. 2023, Feb 09; e0160022.
  1. 10.   Structure of Helicobacter pylori dihydroneopterin aldolase suggests a fragment-based strategy for isozyme-specific inhibitor design
  2. Shaw,Gary; Fan,Lixin; Cherry,Scott; Shi,Genbin; Tropea, Joseph E; Ji,Xinhua
  3. Current Research in Structural Biology. 2023, Jan 30; 5: 100095.
  1. 11.   Visual acuity and vision-related quality of life outcomes following cataract surgery in Ebola virus disease survivors
  2. Taraborelli, Donna; Thomas, Joanne J; Kim, Lucas; Fashina, Tolulope; Hayek, Brent; Mattia, John G; Vandy, Matthew; Sugar, Elizabeth; Crozier,Ian; Yeh, Steven; Shantha, Jessica G
  3. Global Journal of Cataract Surgery and Research in Ophthalmology. 2023, May-Aug; 2(2): 23-29.
  1. 12.   Demographic and Disease-Related Predictors of Socioemotional Development in Children with Neurofibromatosis Type 1 and Plexiform Neurofibromas: An Exploratory Study
  2. Hou, Yang; Wu, Xian; Liu, Dan; Martin, Staci; Tamula,Mary Anne; Allen, Taryn; Baldwin,Andrea; Gillespie, Andy; Goodwin, Anne; Widemann, Brigitte C; Wolters, Pamela L
  3. Cancers. 2022, Dec 01; 14(23):
  1. 13.   An in vitro and computational validation of a novel loss-of-functional mutation in PAX9 associated with non-syndromic tooth agenesis
  2. Sarkar,Tanmoy; Ranjan, Prashant; Kanathur, Smitha; Gupta, Ankush; Das, Parimal
  3. Molecular Genetics and Genomics : MGG. 2022, Nov 14;
  1. 14.   Evaluation of the key geriatric assessment constructs in primary brain tumor population - a descriptive study
  2. Sass, Dilorom; Vera, Elizabeth; Choi, Anna; Acquaye, Alvina; Briceno, Nicole; Christ, Alexa; Grajkowska, Ewa; Jammula, Varna; Levine, Jason; Lindsley, Matthew; Reyes, Jennifer; Roche, Kayla; Rogers, James L; Timmer, Michael; Boris,Lisa; Burton, Eric; Lollo, Nicole; Panzer, Marissa; Penas-Prado, Marta; Pillai, Valentina; Polskin,Lily; Theeler, Brett J; Wu, Jing; Gilbert, Mark R; Armstrong, Terri S; Leeper, Heather
  3. Journal of Geriatric Oncology. 2022, Aug 27; 13(8): 1194-1202.
  1. 15.   ADGRL1 haploinsufficiency causes a variable spectrum of neurodevelopmental disorders in humans and alters synaptic activity and behavior in a mouse model
  2. Vitobello, Antonio; Mazel, Benoit; Lelianova, Vera G; Zangrandi, Alice; Petitto, Evelina; Suckling, Jason; Salpietro, Vincenzo; Meyer, Robert; Elbracht, Miriam; Kurth, Ingo; Eggermann, Thomas; Benlaouer, Ouafa; Lall, Gurprit; Tonevitsky, Alexander G; Scott, Daryl A; Chan, Katie M; Rosenfeld, Jill A; Nambot, Sophie; Safraou, Hana; Bruel, Ange-Line; Denommé-Pichon, Anne-Sophie; Tran Mau-Them, Frédéric; Philippe, Christophe; Duffourd, Yannis; Guo, Hui; Petersen, Andrea K; Granger, Leslie; Crunk, Amy; Bayat, Allan; Striano, Pasquale; Zara, Federico; Scala, Marcello; Thomas, Quentin; Delahaye, Andrée; de Sainte Agathe, Jean-Madeleine; Buratti, Julien; Kozlov,Serguei; Faivre, Laurence; Thauvin-Robinet, Christel; Ushkaryov, Yuri
  3. American Journal of Human Genetics. 2022, Jul 29; 109(8): 1436-1457..
  1. 16.   Heterobifunctional molecules tackle targeted protein dephosphorylation
  2. Sibley, Christopher D; Schneekloth, John S
  3. Trends in Pharmacological Sciences. 2022, Jan 28;
  1. 17.   High-Resolution Ribosome Profiling for Determining Ribosome Functional States During Translation Elongation
  2. Shafieinouri,Mohammad; Santiago Membreno,Britnie; Wu,Colin
  3. Methods in Molecular Biology (Clifton, N.J.). 2022 2428: 173-186.
  1. 18.   Single-cell atlas of tumor cell evolution in response to therapy in hepatocellular carcinoma and intrahepatic cholangiocarcinoma
  2. Ma, Lichun; Wang, Limin; Khatib, Subreen A; Chang, Ching-Wen; Heinrich, Sophia; Dominguez, Dana A; Forgues, Marshonna; Candia, Julián; Hernandez,Maria; Kelly,Michael; Zhao,Yongmei; Tran,Bao; Hernandez, Jonathan M; Davis, Jeremy L; Kleiner, David E; Wood, Bradford J; Greten, Tim F; Wang, Xin Wei
  3. Journal of Hepatology. 2021, Dec; 75(6): 1397-1408.
  1. 19.   Adolescents and young adults with neurofibromatosis type 1: A descriptive study of adaptive functioning
  2. Struemph,Kari; Watts, Adreanna T M; Wolters, Pamela L; Tamula,Mary Anne; Baldwin,Andrea; Widemann, Brigitte; Martin, Staci
  3. American Journal of Medical Genetics Part A. 2021, Nov 03;
  1. 20.   Application of CHyMErA Cas9-Cas12a combinatorial genome-editing platform for genetic interaction mapping and gene fragment deletion screening
  2. Aregger,Michael; Xing, Kun; Gonatopoulos Pournatzis,Thomas
  3. Nature Protocols . 2021, Sep 10; 16(10): 4722-4765.
  1. 21.   Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b] thiophene derivatives as potent apoptosis-inducing agents
  2. Romagnoli, Romeo; Preti, Delia; Hamel,Ernest; Bortolozzi, Roberta; Viola, Giampietro; Brancale, Andrea; Ferla, Salvatore; Morciano, Giampaolo; Pinton, Paolo
  3. Bioorganic chemistry. 2021, Jul; 112
  1. 22.   Immunodeficiency and bone marrow failure with mosaic and germline TLR8 gain of function
  2. Aluri, Jahnavi; Bach, Alicia; Kaviany, Saara; Paracatu, Luana Chiquetto; Kitcharoensakkul, Maleewan; Walkiewicz, Magdalena A.; Putnam, Christopher D.; Shinawi, Marwan; Saucier, Nermina; Rizzi, Elise M.; Harmon, Michael T.; Keppel, Molly P.; Ritter, Michelle; Similuk, Morgan; Kulm,Elaine; Joyce, Michael; de Jesus, Adriana A.; Goldbach-Mansky, Raphaela; Lee, Yi-Shan; Cella, Marina; Kendall, Peggy L.; Dinauer, Mary C.; Bednarski, Jeffrey J.; Bemrich-Stolz, Christina; Canna, Scott W.; Abraham, Shirley M.; Demczko, Matthew M.; Powell, Jonathan; Jones, Stacie M.; Scurlock, Amy M.; De Ravin, Suk See; Bleesing, Jack J.; Connelly, James A.; Rao, V. Koneti; Schuettpelz, Laura G.; Cooper, Megan A.
  3. Blood. 2021, May 6; 137(18): 2450-2462.
  1. 23.   Epidemiological and ES cell-based Functional Evaluation of BRCA2 Variants Identified in Families with Breast Cancer
  2. O'Sullivan,Theresa; Thirthagiri, Eswary; Chong, Chan-Eng; Stauffer,Stacey; Reid,Susan; Southon,Eileen; Hassan, Tiara; Ravichandran, Aravind; Wijaya, Eldarina; Lim, Joanna; Taib, Nur Aishah Mohd; Fadzli, Farhana; Yip, Cheng Har; Hartman, Mikael; Li, Jingmei; van Dam, Rob M; North, Susan L; Das, Ranabir; Easton, Douglas F; Biswas,Kajal; Teo, Soo-Hwang; Sharan,Shyam
  3. Human Mutation. 2021, Feb; 42(2): 200-212.
  1. 24.   Prolonged Posttreatment Virologic Control and Complete Seroreversion After Advanced Human Immunodeficiency Virus-1 Infection
  2. Uruena, Analia; Cassetti, Isabel; Kashyap, Neena; Deleage,Claire; Estes, Jacob D; Trindade, Christopher; Hammoud, Dima A; Burbelo, Peter D; Natarajan,Ven; Dewar,Robin; Imamichi, Hiromi; Ward, Addison J; Poole, April; Ober, Alexander; Rehm, Catherine; Jones,Sara; Liang, C Jason; Chun, Tae-Wook; Nath, Avindra; Lane, H Clifford; Smith, Bryan R; Connors, Mark; Migueles, Stephen A
  3. Open Forum Infectious Diseases. 2021, Jan; 8(1): ofaa613.
  1. 25.   Pogz deficiency leads to transcription dysregulation and impaired cerebellar activity underlying autism-like behavior in mice
  2. Suliman-Lavie, Reut; Title, Ben; Cohen, Yahel; Hamada, Nanako; Tal, Maayan; Tal, Nitzan; Monderer-Rothkoff, Galya; Gudmundsdottir, Bjorg; Gudmundsson,Kristbjorn; Keller,Jonathan; Huang, Guo-Jen; Nagata, Koh-Ichi; Yarom, Yosef; Shifman, Sagiv
  3. Nature communications. 2020, NOV 17; 11(1): 5836.
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