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  1. 1.   The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma
  2. Ricketts, Christopher J; De Cubas, Aguirre A; Fan, Huihui; Smith, Christof C; Lang, Martin; Reznik, Ed; Bowlby, Reanne; Gibb, Ewan A; Akbani, Rehan; Beroukhim, Rameen; Bottaro, Donald P; Choueiri, Toni K; Gibbs, Richard A; Godwin, Andrew K; Haake, Scott; Hakimi, A Ari; Henske, Elizabeth P; Hsieh, James J; Ho, Thai H; Kanchi, Rupa S; Krishnan, Bhavani; Kwaitkowski, David J; Lui, Wembin; Merino, Maria J; Mills, Gordon B; Myers, Jerome; Nickerson, Michael L; Reuter, Victor E; Schmidt, Laura S; Shelley, C Simon; Shen, Hui; Shuch, Brian; Signoretti, Sabina; Srinivasan, Ramaprasad; Tamboli, Pheroze; Thomas, George; Vincent, Benjamin G; Vocke, Cathy D; Wheeler, David A; Yang, Lixing; Kim, William T; Robertson, A Gordon; Spellman, Paul T; Rathmell, W Kimryn; Linehan, W Marston
  3. Cell Reports. 2018, Apr 03; 23(1): 313-326.e5.
  1. 2.   DNA Methyltransferase Inhibitor, Zebularine, Delays Tumor Growth and Induces Apoptosis in a Genetically Engineered Mouse Model of Breast Cancer
  2. Chen, M.; Shabashvili, D.; Nawab, A.; Yang, S. X.; Dyer, L. M.; Brown, K. D.; Hollingshead, M.; Hunter, K. W.; Kaye, F. J.; Hochwald, S. N.; Marquez, V. E.; Steeg, P.; Zajac-Kaye, M.
  3. Molecular Cancer Therapeutics. 2012, Feb; 11(2): 370-382.
  1. 3.   Long-term Epigenetic Therapy with Oral Zebularine Has Minimal Side Effects and Prevents Intestinal Tumors in Mice
  2. Yoo, C. B.; Chuang, J. C.; Byun, H. M.; Egger, G.; Yang, A. S.; Dubeau, L.; Long, T.; Laird, P. W.; Marquez, V. E.; Jones, P. A.
  3. Cancer Prevention Research. 2008 1(4): 233-240.
  1. 4.   Multiple tumor suppressor genes are increasingly methylated with age in non-neoplastic gastric epithelia
  2. So, K. J.; Tamura, G.; Honda, T.; Homma, N.; Waki, T.; Togawa, N.; Nishizuka, S.; Motoyama, T.
  3. Cancer Science. 2006, Nov; 97(11): 1155-1158.
  1. 5.   Quantitative assessment of RUNX3 methylation in neoplastic and non-neoplastic gastric epithelia using a DNA microarray
  2. So, K.; Tamura, G.; Honda, T.; Homma, N.; Endoh, M.; Togawa, N.; Nishizuka, S.; Motoyama, T.
  3. Pathology International. 2006, Oct; 56(10): 571-575.
  1. 6.   The novel DNA methylation inhibitor zebularine is effective against the development of murine T-cell lymphoma
  2. Herranz, M.; Martin-Caballero, J.; Fraga, M. F.; Ruiz-Cabello, J.; Flores, J. M.; Desco, M.; Marquez, V.; Esteller, M.
  3. Blood. 2006, FEB 1; 107(3): 1174-1177.
  1. 7.   Gene promoter methylation in prostate tumor-associated stromal cells
  2. Hanson, J. A.; Gillespie, J. W.; Grover, A.; Tangrea, M. A.; Chuaqui, R. F.; Emmert-Buck, M. R.; Tangrea, J. A.; Libutti, S. K.; Linehan, W. M.; Woodson, K. G.
  3. Journal of the National Cancer Institute. 2006, Feb; 98(4): 255-261.
  1. 8.   High-content fluorescence-based screening for epigenetic-modulators
  2. Martinez, E. D.; Dull, A. B.; Beutler, J. A.; Hager, G. L.
  3. Measuring Biological Responses with Automated Microscopy. 2006; 414 : 21-36.
  1. 9.   Spreading of methylation within RUNX3 CpG island in gastric cancer
  2. Homma, N.; Tamura, G.; Honda, T.; Matsumoto, Y.; Nishizuka, S.; Kawata, S.; Motoyama, T.
  3. Cancer Science. 2006, JAN; 97(1): 51-56.
  1. 10.   Enhancement of in vitro and in vivo tumor cell radiosensitivity by the DNA methylation inhibitor zebularine
  2. Dote, H.; Cerna, D.; Burgan, W. E.; Carter, D. J.; Cerra, M. A.; Hollingshead, M. G.; Camphausen, K.; Tofilon, P. J.
  3. Clinical Cancer Research. 2005, JUN 15; 11(12): 4571-4579.
  1. 11.   Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation
  2. Hodge, D. R.; Peng, B.; Cherry, J. C.; Hurt, E. M.; Fox, S. D.; Kelley, J. A.; Munroe, D. J.; Farrar, W. L.
  3. Cancer Research. 2005, JUN 1; 65(11): 4673-4682.
  1. 12.   Epigenetic silencing of manganese superoxide dismutase (SOD-2) in KAS 6/1 human multiple myeloma cells increases cell proliferation
  2. Hodge, D. R.; Peng, B.; Pompeia, C.; Thomas, S.; Cho, E.; Clausen, P. A.; Marquez, V. E.; Farrar, W. L.
  3. Cancer Biology & Therapy. 2005, May; 4(5): 585-592.
  1. 13.   Epigenetic silencing of the human nucleotide excision repair gene, hHR23B, in interleukin-6-responsive multiple myeloma KAS-6/1 cells
  2. Pengt, B.; Hodge, D. R.; Thomas, S. B.; Cherry, J. M.; Munroe, D. J.; Pompeia, C.; Xiao, W. H.; Farrar, W. L.
  3. Journal of Biological Chemistry. 2005, FEB 11; 280(6): 4182-4187.
  1. 14.   Microarray analysis of epigenetic silencing of gene expression in the KAS-6/1 multiple myeloma cell line
  2. Pompeia, C.; Hodge, D. R.; Plass, C.; Wu, Y. Z.; Marquez, V. E.; Kelley, J. A.; Farrar, W. L.
  3. Cancer Research. 2004 64(10): 3465-3473.
  1. 15.   A novel retrovirus provides the cooperating oncogenic event(s) required to demonstrate the tumor suppressor activity of p15(Ink4b) in myeloid cells in vivo
  2. Wolff, L.; Garin, M. T.; Koller, R.; Bies, J.; Tessarollo, L.; Anver, M. R.; Powell, D.; Perella, C.
  3. Blood Cells Molecules and Diseases. 2004, JAN-FEB; 32(1): 226-231.
  1. 16.   Inactivation of RAS association domain family 1A gene in cervical carcinomas and the role of human papillomavirus infection
  2. Kuzmin, I.; Liu, L. M.; Dammann, R.; Geil, L.; Stanbridge, E. J.; Wilczynski, S. P.; Lerman, M. I.; Pfeifer, G. P.
  3. Cancer Research. 2003 63(8): 1888-1893.
  1. 17.   Epigenetic inactivation of RASSF1A in head and neck cancer
  2. Dong, S. M.; Sun, D. I.; Benoit, N. E.; Kuzmin, I.; Lerman, M. I.; Sidransky, D.
  3. Clinical Cancer Research. 2003 9(10, Part 1): 3635-3640.
  1. 18.   Hypermethylation of the Ink4b locus in murine myeloid leukemia and increased susceptibility to leukemia in p15(Ink4b)- defficient mice
  2. Wolff, L.; Garin, M. T.; Koller, R.; Bies, J.; Liao, W.; Malumbres, M.; Tessarollo, L.; Powell, D.; Perella, C.
  3. Oncogene. 2003 22(58): 9265-9274.
  1. 19.   Loss of the tight junction protein claudin-7 correlates with histological grade in both ductal carcinoma in situ and invasive ductal carcinoma of the breast
  2. Kominsky, S. L.; Argani, P.; Korz, D.; Evron, E.; Raman, V.; Garrett, E.; Rein, A.; Sauter, G.; Kallioniemi, O. P.; Sukumar, S.
  3. Oncogene. 2003 22(13): 2021-2033.
  1. 20.   The RASSF1A tumor suppressor gene is inactivated in prostate tumors and suppresses growth of prostate carcinoma cells
  2. Kuzmin, I.; Gillespie, J. W.; Protopopov, A.; Geil, L.; Dreijerink, K.; Yang, Y. F.; Vocke, C. D.; Duh, F. M.; Zabarovsky, E.; Minna, J. D.; Rhim, J. S.; Emmert-Buck, M. R.; Linehan, W. M.; Lerman, M. I.
  3. Cancer Research. 2002 62(12): 3498-3502.
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