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  1. 1.   Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine
  2. Maciag,Anna; Yang, Yue; Sharma,Alok; Turner,David; Dehart,Caroline; Abdelkarim, Hazem; Fan,Lixin; Smith,Brian; Kumari,Vandana; Dyba,Marcin; Rigby,Megan; Castillo Badillo,Jean; Adams, Lauren; Fornelli, Luca; Fox, Stephen; Brafman, Alla; Turbyville,Thomas; Gillette,William; Messing,Simon; Agamasu, Constance; Wolfe, Andrew L; Gysin, Stephan; Chan, Albert H; Simanshu,Dhirendra; Esposito,Dominic; Chertov,Oleg; Stephen,Andrew; Arkin, Michelle; Renslo, Adam; Kelleher, Neil L; Gaponenko, Vadim; Lightstone, Felice C; Nissley,Dwight; McCormick, Frank
  3. Proceedings of the National Academy of Sciences of the United States of America. 2025, May 13; 122(19): e2410766122.
  1. 2.   Development of patient reported outcome measures assessing tumor pain intensity and tumor pain interference for individuals with neurofibromatosis type 1 and plexiform neurofibromas: qualitative findings
  2. Al Ghriwati, Nour; Struemph, Kari; Martin, Staci; Little, Paige; Baker, Melissa; Levine, Jason; MacKenzie, Cynthia; Tonsgard, James; Schorry, Elizabeth K; Walsh, Karin S; Wolters, Pamela L
  3. Journal of Patient-Reported Outcomes. 2025, Apr 30; 9(1): 46.
  1. 3.   Distinct allosteric networks in CDK4 and CDK6 in the cell cycle and in drug resistance
  2. Zhang,Wengang; Bradburn, Devin; Heidebrink, Gretchen; Liu, Yonglan; Jang,Hyunbum; Nussinov,Ruth; Kõivomägi, Mardo
  3. Journal of Molecular Biology. 2025, Mar 31; 169121.
  1. 4.   PRGN-2009 and bintrafusp alfa for patients with advanced or metastatic human papillomavirus-associated cancer
  2. Floudas, Charalampos S; Goswami, Meghali; Donahue, Renee N; Strauss, Julius; Pastor, Danielle M; Redman, Jason M; Brownell, Isaac; Turkbey, Evrim B; Steinberg, Seth M; Cordes, Lisa M; Marté, Jennifer L; Khan, Maheen H; McMahon, Sheri; Lamping, Elizabeth; Manu,Michell; Manukyan,Manuk; Brough, Douglas E; Lankford, Amy; Jochems, Caroline; Schlom, Jeffrey; Gulley, James L
  3. Cancer Immunology, Immunotherapy : CII. 2025, Mar 21; 74(5): 155.
  1. 5.   The human oral microbiome and risk of colorectal cancer within three prospective cohort studies in the United States
  2. Vogtmann, Emily; Yano, Yukiko; Zouiouich, Semi; Hua,Xing; Wan, Yunhu; Purandare, Vaishnavi; Li, Shilan; Dagnall,Casey; Jones, Kristine; Hicks,Belynda; Hutchinson,Amy; Caporaso, J Gregory; Wheeler, William; Huang, Wen-Yi; Freedman, Neal D; Sandler, Dale P; Beane Freeman, Laura E; Liao, Linda M; Gail, Mitchell H; Shi, Jianxin; Abnet, Christian C; Sinha, Rashmi
  3. Cancer. 2025, Mar 15; 131(6): e35802.
  1. 6.   Inhibition of Ribosome Biogenesis in vivo Causes p53-Dependent Death and p53-Independent Dysfunction
  2. Cho, Charles J; Nguyen, Thanh; Rougeau, Amala K; Huang, Yang-Zhe; To, Sarah; Lin, Xiaobo; Thalalla Gamage,Supuni; Meier,Jordan; Mills, Jason C
  3. Cellular and Molecular Gastroenterology and Hepatology. 2025, Mar 11; 101496.
  1. 7.   Combinatorial screen of targeted agents with the PI3K inhibitors inavolisib, alpelisib, duvelisib, and copanlisib in multi-cell type tumor spheroids
  2. Dexheimer,Tom; Davoudi,Zahra; Coussens,Nathan; Silvers,Thomas; Morris, Joel; Takebe, Naoko; Said, Rabih; Moscow, Jeffrey A; Doroshow, James H; Teicher, Beverly A
  3. SLAS Discovery : advancing life sciences R & D. 2025, Feb 23; 100222.
  1. 8.   Effects of high-fiber, high-fruit and high-vegetable, low-fat dietary intervention on the rectal tissue microbiome
  2. Byrd, Doratha A; Gomez, Maria; Hogue, Stephanie; Wan, Yunhu; Ortega-Villa, Ana; Warner,Andrew; Dagnall,Casey; Jones,Kristine; Hicks,Belynda; Albert, Paul; Murphy, Gwen; Sinha, Rashmi; Vogtmann, Emily
  3. Journal of the National Cancer Institute. 2025, Feb 18;
  1. 9.   Olaparib in treatment-refractory isocitrate dehydrogenase 1 (IDH1)- and IDH2-mutant cholangiocarcinoma: Safety and antitumor activity from the phase 2 National Cancer Institute 10129 trial
  2. Cecchini, Michael; Pilat, Mary Jo; Uboha, Nataliya; Azad, Nilofer S; Cho, May; Davis, Elizabeth J; Ahnert, Jordi Rodon; Tinoco, Gabriel; Shapiro, Geoffrey I; Khagi, Simon; Powers, Benjamin; Spencer, Kristen; Groisberg, Roman; Drappatz, Jan; Chen, Li; Das,Bishu; Bao, Xun; Li, Jing; Narayan, Azeet; Vu, Dennis; Patel, Abhijit; Niger, Monica; Doroshow, Deborah; Durecki, Diane; Boerner, Scott A; Bindra, Ranjit; Ivy, Percy; Shyr, Derek; Shyr, Yu; LoRusso, Patricia M
  3. Cancer. 2025, Feb 15; 131(4): e35755.
  1. 10.   Structural basis for complement receptor engagement and virus neutralization through Epstein-Barr virus gp350
  2. Joyce, M Gordon; Bu, Wei; Chen, Wei-Hung; Gillespie, Rebecca A; Andrews, Sarah F; Wheatley, Adam K; Tsybovsky,Yaroslav; Jensen, Jaime L; Stephens,Tyler; Prabhakaran, Madhu; Fisher, Brian E; Narpala, Sandeep R; Bagchi, Meghna; McDermott, Adrian B; Nabel, Gary J; Kwong, Peter D; Mascola, John R; Cohen, Jeffrey I; Kanekiyo, Masaru
  3. Immunity. 2025, Feb 11; 58(2): 295-308.e5. .
  1. 11.   The integrated stress response regulates 18S nonfunctional rRNA decay in mammals
  2. Coria,Aaztli; Shah,Akruti; Shafieinouri,Mohammad; Taylor, Sarah J; Orgebin,Emilien; Guiblet,Wilfried; Miller,Jennifer; Sharma, Indra Mani; Wu, Colin Chih-Chien
  3. Molecular Cell. 2025, Feb 07;
  1. 12.   Biochemical and biophysical characterization of inositol-tetrakisphosphate 1-kinase inhibitors
  2. Ng,Martin; Wang, Huanchen; Zhang, Haibo; Prucker, Isabel; Perera, Lalith; Goncharova,Katya; Wamiru,Antony; Jessen, Henning J; Stanley, Robin E; Shears, Stephen B; Luo, Ji; O'Keefe,Barry; Wilson,Brice
  3. The Journal of Biological Chemistry. 2025, Feb 06; 108274.
  1. 13.   Allosteric modulation of NF1 GAP: Differential distributions of catalytically competent populations in loss-of-function and gain-of-function mutants
  2. Xu,Liang; Jang,Hyunbum; Nussinov,Ruth
  3. Protein Science : a publication of the Protein Society. 2025, Feb; 34(2): e70042.
  1. 14.   Drug-Linker Constructs Bearing Unique Dual-Mechanism Tubulin Binding Payloads Tethered through Cleavable and Non-Cleavable Linkers
  2. Ford, Jacob W; VanNatta, Jennifer M; Mondal, Deboprosad; Lin, Chen-Ming; Deng, Yuling; Bai, Ruoli; Hamel,Ernest; Trawick, Mary Lynn; Pinney, Kevin G
  3. Tetrahedron. 2025, Feb 01; 171
  1. 15.   Whole-body PET imaging of simian immunodeficiency virus using gp120-targeting probes fails to reveal regions of specific uptake in rhesus macaques
  2. Srinivasula, Sharat; Kim, Insook; Jang, Hyukjin; Degrange, Paula; Brown, Heather; Dalton, Viviana; Badralmaa,Yunden; Natarajan,Ven; Long, Brad; Carrasquillo, Jorge A; Di Mascio, Michele
  3. European Journal of Nuclear Medicine and Molecular Imaging. 2025, Jan 31;
  1. 16.   A Mixed Methods Study of Medication Adherence in Adults with Neurofibromatosis Type 1 (NF1) on a Clinical Trial of Selumetinib
  2. Curlee, Millicent S; Toledo-Tamula, Mary Anne; Baker, Melissa; Wikstrom, Daniel; Harrison, Cynthia; Rhodes, Amanda; Fagan, Margaret; Tibery,Cecilia; Wolters, Pamela L; Widemann, Brigitte C; Gross, Andrea M; Martin, Staci
  3. Cancers. 2025, Jan 17; 17(2):
  1. 17.   Fun in the sun: ribosomes defend against UV irradiation
  2. Coria,Aaztli; Orgebin,Emilien; Wu,Colin
  3. Trends in Cell Biology. 2025, Jan 16;
  1. 18.   Unraveling the dynamics of B7-H3-targeting therapeutic antibodies in cancer through PET imaging and antibody pharmacokinetics
  2. Fernandes, Bruna; Olkowski, Colleen P; Ghaemi, Behnaz; Basuli, Falguni; Shi, Jianfeng; Kiesewetter, Dale O; Lang, Lixin; Elijah, Edmondson; Swenson, Rolf; Choyke, Peter L; Lin, Frank I; Jacobson, Orit
  3. Journal of Controlled Release : official journal of the Controlled Release Society. 2025, Jan 13;
  1. 19.   Fine-tuning probes for fluorescence polarization binding assays of bivalent ligands against polo-like kinase 1 using full-length protein
  2. Tsuji, Kohei; Tamamura, Hirokazu; Burke,Terrence
  3. Bioorganic & Medicinal Chemistry . 2024, Dec 28; 119: 118055.
  1. 20.   The differential interactomes of the KRAS splice variants identify BIRC6 as a ubiquitin ligase for KRAS4A
  2. Kochen Rossi, Juan; Nuevo-Tapioles, Cristina; O'Keefe, Rachel A; Hunkeler, Moritz; Schmoker, Anna M; Fissore-O'Leary, Mercedes; Su, Wenjuan; Ahearn, Ian M; Branco, Cristina; Cheong, Hakyung; Esposito,Dom; Clotea, Ioana; Ueberheide, Beatrix; Fischer, Eric S; Philips, Mark R
  3. Cell Reports. 2024, Dec 19; 44(1): 115087.
  1. 21.   Benzyl Ammonium Carbamates Undergo Two-Step Linker Cleavage and Improve the Properties of Antibody Conjugates
  2. Li,Xiaoyi; Patel,Nimit; Kalen,Joseph; Schnermann,Martin
  3. Angewandte Chemie (International ed. in English). 2024, Dec 18; e202417651.
  1. 22.   Immune profile diversity is achieved with synthetic TLR4 agonists combined with the RG1-VLP vaccine in mice
  2. Matthews, Rebecca L; Khan,Nazneen; Beckman,Bradley; Sharma, Simran; Dietz, Zackary; Picking, William D; Izmirlian, Grant; Sanders,Chelsea; Stocks,Stacy; Difilippantonio,Simone; Kirnbauer, Reinhard; Roden, Richard B; Pinto,Ligia; Shoemaker, Robert H; Ernst, Robert K; Marshall,Jason
  3. Vaccine. 2024, Dec 03; 126577.
  1. 23.   Insights into biofilm architecture and maturation enable improved clinical strategies for exopolysaccharide-targeting therapeutics
  2. Temme,Joel; Tan, Zibin; Li,Mi; Yang,Mo; Wlodawer,Alexander; Huang, Xuefei; Schneekloth,Jay; Gildersleeve,Jeffrey
  3. Cell Chemical Biology. 2024, Dec 02;
  1. 24.   Co-incubation of Short Amphiphilic Peptides with Dicer Substrate RNAs Results in ß-Sheet Fibrils for Enhanced Gene Silencing in Cancer Cells
  2. Gupta, Kshitij; Parlea, Lorena; Puri,Anu; Smith, Katelyn; Puri,Anu; Bergman, Joseph T; Kim, Taejin; Shapiro,Bruce
  3. RNA Nanomed. 2024, Dec; 1(1): 61-78.
  1. 25.   Association of changes in expression of HDAC and SIRT genes after drug treatment with cancer cell line sensitivity to kinase inhibitors
  2. Krushkal, Julia; Zhao, Yingdong; Roney, Kyle; Zhu, Weimin; Brooks,Alan; Wilsker,Deborah; Parchment, Ralph E; McShane, Lisa M; Doroshow, James H
  3. Epigenetics. 2024, Dec; 19(1): 2309824.
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