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  1. 1.   The lectins griffithsin, cyanovirin-N and scytovirin inhibit HIV-1 binding to the DC-SIGN receptor and transfer to CD4(+) cells
  2. Alexandre, K. B.; Gray, E. S.; Mufhandu, H.; McMahon, J. B.; Chakauya, E.; O'Keefe, B. R.; Chikwamba, R.; Morris, L.
  3. Virology. 2012, Feb; 423(2): 175-186.
  1. 2.   Investigation of Griffithsin's Interactions with Human Cells Confirms Its Outstanding Safety and Efficacy Profile as a Microbicide Candidate
  2. Kouokam, J. C.; Huskens, D.; Schols, D.; Johannemann, A.; Riedell, S. K.; Walter, W.; Walker, J. M.; Matoba, N.; O'Keefe, B. R.; Palmer, K. E.
  3. Plos One. 2011, Aug; 6(8):
  1. 3.   Anti-HIV microbicide development: targeting the virus is the key
  2. O'Keefe, B. R.
  3. Future Virology. 2011, May; 6(5): 553-556.
  1. 4.   Monomerization of Viral Entry Inhibitor Griffithsin Elucidates the Relationship between Multivalent Binding to Carbohydrates and anti-HIV Activity
  2. Moulaei, T.; Shenoy, S. R.; Giomarelli, B.; Thomas, C.; McMahon, J. B.; Dauter, Z.; O'Keefe, B. R.; Wlodawer, A.
  3. Structure. 2010, Sep; 18(9): 1104-1115.
  1. 5.   High Throughput Extraction of Plant, Marine and Fungal Specimens for Preservation of Biologically Active Molecules
  2. McCloud, T. G.
  3. Molecules. 2010, Jul; 15(7): 4526-4563.
  1. 6.   Mannose-rich glycosylation patterns on HIV-1 subtype C gp120 and sensitivity to the lectins, Griffithsin, Cyanovirin-N and Scytovirin
  2. Alexandre, K. B.; Gray, E. S.; Lambson, B. E.; Moore, P. L.; Choge, I. A.; Mlisana, K.; Karim, S. S. A.; McMahon, J.; O'Keefe, B.; Chikwamba, R.; Morris, L.
  3. Virology. 2010, Jun; 402(1): 187-196.
  1. 7.   Broad-Spectrum In Vitro Activity and In Vivo Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family Coronaviridae
  2. O'Keefe, B. R.; Giomarelli, B.; Barnard, D. L.; Shenoy, S. R.; Chan, P. K. S.; McMahon, J. B.; Palmer, K. E.; Barnett, B. W.; Meyerholz, D. K.; Wohlford-Lenane, C. L.; McCray, P. B.
  3. Journal of Virology. 2010, Mar; 84(5): 2511-2521.
  1. 8.   Multivalent Interactions with gp120 Are Required for the Anti-HIV Activity of Cyanovirin
  2. Liu, Y. A.; Carroll, J. R.; Holt, L. A.; McMahon, J.; Giomarelli, B.; Ghirl, a
  3. Biopolymers. 2009 92(3): 194-200.
  1. 9.   Treatment of influenza A (H1N1) virus infections in mice and ferrets with cyanovirin-N
  2. Smee, D. F.; Bailey, K. W.; Wong, M. H.; O'Keefe, B. R.; Gustafson, K. R.; Mishin, V. P.; Gubareva, L. V.
  3. Antiviral Research. 2008 80(3): 266-271.
  1. 10.   A monovalent mutant of cyanovirin-N provides insight into the role of multiple interactions with gp120 for antiviral activity
  2. Fromme, R.; Katiliene, Z.; Giomarelli, B.; Bogani, F.; Mc Mahon, J.; Mori, T.; Fromme, P.; Ghirl, a
  3. Biochemistry. 2007, Aug; 46(32): 9199-9207.
  1. 11.   An activity-dependent assay for ricin and related RNA N-glycosidases based on electrochemiluminescence
  2. Keener, W. K.; Rivera, V. R.; Young, C. C.; Poli, M. A.
  3. Analytical Biochemistry. 2006, Oct; 357(2): 200-207.
  1. 12.   Cyanovirin-N inhibits hepatitis C virus entry by binding to envelope protein glycans
  2. Helle, F.; Wychowski, C.; Vu-Dac, N.; Gustafson, K. R.; Voisset, C.; Dubuisson, J.
  3. Journal of Biological Chemistry. 2006, Sep; 281(35): 25177-25183.
  1. 13.   Potent anti-HIV activity of scytovirin domain 1 peptide
  2. Xiong, C. Y.; O'Keefe, B. R.; Byrd, R. A.; McMahon, J. B.
  3. Peptides. 2006, Jul; 27(7): 1668-1675.
  1. 14.   Domain-swapped structure of the potent antiviral protein griffithsin and its mode of carbohydrate binding
  2. Ziolkowska, N. E.; O'Keefe, B. R.; Mori, T.; Zhu, C.; Giomarelli, B.; Vojdani, F.; Palmer, K. E.; McMahon, J. B.; Wlodawer, A.
  3. Structure. 2006, Jul; 14(7): 1127-1135.
  1. 15.   Recombinant production of anti-HIV protein, griffithsin, by auto-induction in a fermentor culture
  2. Giomarelli, B.; Schumacher, K. M.; Taylor, T. E.; Sowder, R. C.; Hartley, J. L.; McMahon, J. B.; Mori, T.
  3. Protein Expression and Purification. 2006, MAY; 47(1): 194-202.
  1. 16.   Overexpression and purification of scytovirin, a potent, novel anti-HIV protein from the cultured cyanobacterium Scytonema varium
  2. Xiong, C. Y.; O'Keefe, B. R.; Botos, I.; Wlodawer, A.; McMahon, J. B.
  3. Protein Expression and Purification. 2006, Apr; 46(2): 233-239.
  1. 17.   Effects of Gag mutation and processing on retroviral dimeric RNA maturation
  2. Fu, W.; Dang, Q.; Nagashima, K.; Freed, E. O.; Pathak, V. K.; Hu, W. S.
  3. Journal of Virology. 2006, FEB; 80(3): 1242-1249.
  1. 18.   Structural studies of algal lectins with anti-HIV activity
  2. Ziolkowska, N. E.; Wlodawer, A.
  3. Acta Biochimica Polonica. 2006 53(4): 617-626.
  1. 19.   Resistance of human immunodeficiency virus type 1 to the high-mannose binding agents cyanovirin N and concanavalin A
  2. Witvrouw, M.; Fikkert, V.; Hantson, A.; Pannecouque, C.; O'Keefe, B. R.; McMahon, J.; Stamatatos, L.; De Clercq, E.; Bolmstedt, A.
  3. Journal of Virology. 2005, JUN; 79(12): 7777-7784.
  1. 20.   Isolation and characterization of griffithsin, a novel HIV-inactivating protein, from the red alga Griffithsia sp
  2. Mori, T.; O'Keefe, B. R.; Sowder, R. C.; Bringans, S.; Gardella, R.; Berg, S.; Cochran, P.; Turpin, J. A.; Buckheit, R. W.; McMahon, J. B.; Boyd, M. R.
  3. Journal of Biological Chemistry. 2005, MAR 11; 280(10): 9345-9353.
  1. 21.   Vpr protein of human immunodeficiency virus type 1 binds to 14-3-3 proteins and facilitates complex formation with Cdc25C: Implications for cell cycle arrest
  2. Kino, T.; Gragerov, A.; Valentin, A.; Tsopanomihalou, M.; Ilyina-Gragerova, G.; Erwin-Cohen, R.; Chrousos, G. P.; Pavlakis, G. N.
  3. Journal of Virology. 2005, MAR; 79(5): 2780-2787.
  1. 22.   Genetic recombination of human immunodeficiency virus type 1 in one round of viral replication: Effects of genetic distance, target cells, accessory genes, and lack of high negative interference in crossover events
  2. Rhodes, T. D.; Nikolaitchik, O.; Chen, J. B.; Powell, D.; Hu, W. S.
  3. Journal of Virology. 2005, FEB; 79(3): 1666-1677.
  1. 23.   Correlation between p14(ARF)/p16(INK4A) expression and HPV infection in uterine cervical cancer
  2. Kanao, H.; Enomoto, T.; Ueda, Y.; Fujita, M.; Nakashima, R.; Ueno, Y.; Miyatake, T.; Yoshizaki, T.; Buzard, G. S.; Kimura, T.; Yoshino, K.; Murata, Y.
  3. Cancer Letters. 2004, SEP 15; 213(1): 31-37.
  1. 24.   Functional characterization of the candidate tumor suppressor gene NPRL2/G21 located in 3p21.3C
  2. Li, F.; Wang, F.; Haraldson, K.; Protopopov, A.; Duh, F. M.; Geil, L.; Kuzmin, I.; Minna, J. D.; Stanbridge, E.; Braga, E.; Kashuba, V. I.; Klein, G.; Lerman, M. I.; Zabarovsky, E. R.
  3. Cancer Research. 2004, SEP 15; 64(18): 6438-6443.
  1. 25.   Development of a fluorescent microplate assay for determining cyanovirin-N levels in plasma
  2. Bringans, S. D.; O'Keefe, B. R.; Bray, M.; Whitehouse, C. A.; Boyd, M. R.
  3. Analytical and Bioanalytical Chemistry. 2004, SEP; 380(2): 269-274.
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