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  1. 1.   PRGN-2009 and bintrafusp alfa for patients with advanced or metastatic human papillomavirus-associated cancer
  2. Floudas, Charalampos S; Goswami, Meghali; Donahue, Renee N; Strauss, Julius; Pastor, Danielle M; Redman, Jason M; Brownell, Isaac; Turkbey, Evrim B; Steinberg, Seth M; Cordes, Lisa M; Marté, Jennifer L; Khan, Maheen H; McMahon, Sheri; Lamping, Elizabeth; Manu,Michell; Manukyan,Manuk; Brough, Douglas E; Lankford, Amy; Jochems, Caroline; Schlom, Jeffrey; Gulley, James L
  3. Cancer Immunology, Immunotherapy : CII. 2025, Mar 21; 74(5): 155.
  1. 2.   Biochemical and biophysical characterization of inositol-tetrakisphosphate 1-kinase inhibitors
  2. Ng,Martin; Wang, Huanchen; Zhang, Haibo; Prucker, Isabel; Perera, Lalith; Goncharova,Katya; Wamiru,Antony; Jessen, Henning J; Stanley, Robin E; Shears, Stephen B; Luo, Ji; O'Keefe,Barry; Wilson,Brice
  3. The Journal of Biological Chemistry. 2025, Feb 06; 108274.
  1. 3.   Autoinhibition of ubiquitin-specific protease 8: insights into domain interactions and mechanisms of regulation
  2. Caba, Cody; Black, Megan; Liu, Yujue; DaDalt, Ashley A; Mallare, Josh; Fan,Lixin; Harding, Rachel J; Wang, Yunxin; Vacratsis, Panayiotis O; Huang, Rui; Zhuang, Zhihao; Tong, Yufeng
  3. The Journal of Biological Chemistry. 2024, Aug 28; 107727.
  1. 4.   Olaparib for childhood tumors harboring defects in DNA damage repair genes: arm H of the NCI-COG Pediatric MATCH trial
  2. Glade Bender, Julia L; Pinkney, Kerice; Williams,Mickey; Roy-Chowdhuri, Sinchita; Patton, David R; Coffey, Brent D; Reid, Joel M; Piao, Jin; Saguilig, Lauren; Alonzo, Todd A; Berg, Stacey L; Ramirez, Nilsa C; Fox, Elizabeth; Weigel, Brenda J; Hawkins, Douglas S; Mooney, Margaret M; Takebe, Naoko; Tricoli, James V; Janeway, Katherine A; Seibel, Nita L; Parsons, Donald W
  3. The Oncologist. 2024, May 30;
  1. 5.   CDK2 inhibition disorders centrosome stoichiometry and alters cellular outcomes in aneuploid cancer cells
  2. Chen,Zibo; Liu,Xi; Kawakami, Masanori; Liu,Xiuxia; Baker, Allison; Bhatawadekar, Aayush; Tyutyunyk-Massey,Liliya; Narayan,Kedar; Dmitrovsky,Ethan
  3. Cancer Biology & Therapy. 2023, Dec 31; 24(1): 2279241.
  1. 6.   Structure Guided Design, Synthesis, and Biological Evaluation of Oxetane-Containing Indole Analogues
  2. Ren, Wen; Vairin, Rebecca; Ward, Jacob D; Francis, Ricardo; VanNatta, Jenny; Bai,Ruoli; Tankoano, Pouguiniseli E; Deng, Yuling; Hamel,Ernest; Trawick, Mary Lynn; Pinney, Kevin G
  3. Bioorganic & Medicinal Chemistry. 2023, Jun 29; 92: 117400.
  1. 7.   RASopathy mutations provide functional insight into the BRAF cysteine-rich domain and reveal the importance of autoinhibition in BRAF regulation
  2. Smith,Russell; Terrell,Elizabeth; Insinna, Christine; Agamasu, Constance; Wagner, Morgan E; Ritt,Daniel; Stauffer,Jimmy; Stephen,Andy; Morrison,Deborah
  3. Molecular Cell. 2022, Nov 17; 82(22): 4262-4276.
  1. 8.   The mechanism of activation of MEK1 by B-Raf and KSR1
  2. Maloney,Ryan; Zhang,Mingzhen; Liu,Yonglan; Jang,Hyunbum; Nussinov,Ruth
  3. Cellular and molecular life sciences : CMLS. 2022, May 04; 79(5): 281.
  1. 9.   Characterization and tissue localization of zebrafish homologs of the human ABCB1 multidrug transporter
  2. Robey, Robert W.; Robinson, Andrea N.; Ali-Rahmani, Fatima; Huff, Lyn M.; Lusvarghi, Sabrina; Vahedi, Shahrooz; Hotz, Jordan M.; Warner,Andrew; Butcher,Donna; Matta,Jennifer; Edmondson,Elijah; Lee, Tobie D.; Roth, Jacob S.; Lee, Olivia W.; Shen, Min; Tanner, Kandice; Hall, Matthew D.; Ambudkar, Suresh; Gottesman, Michael M.
  3. SCIENTIFIC REPORTS. 2021, Dec 17; 11(1):
  1. 10.   INSTIs and NNRTIs Potently Inhibit HIV-1 Polypurine Tract Mutants in a Single Round Infection Assay
  2. Smith, Steven J; Ferris,Andrea; Zhao, Xuezhi; Pauly,Gary; Schneider,Joel; Burke,Terrence; Hughes,Stephen
  3. Viruses. 2021, Dec 14; 13(12):
  1. 11.   The mechanism of Raf activation through dimerization
  2. Zhang,Mingzhen; Maloney,Ryan; Jang,Hyunbum; Nussinov,Ruth
  3. Chemical Science. 2021, Dec 08; 12(47): 15609-15619.
  1. 12.   B-Raf autoinhibition in the presence and absence of 14-3-3
  2. Zhang,Mingzhen; Jang,Hyunbum; Li, Zhigang; Sacks, David B.; Nussinov,Ruth
  3. Structure. 2021, Jul 1; 29(7): 768-777.e2.
  1. 13.   Agelasine Diterpenoids and Cbl-b Inhibitory Ageliferins from the Coralline Demosponge Astrosclera willeyana
  2. Jiang, Wei; Wang,Dongdong; Wilson,Brice; Kang, Unwoo; Bokesch, Heidi R; Smith,Emily; Wamiru,Antony; Goncharova,Katya; Voeller, Donna; Lipkowitz, Stanley; O'Keefe,Barry; Gustafson,Kirk
  3. Marine drugs. 2021, Jun 24; 19(7):
  1. 14.   Phase I Study of Zotiraciclib in Combination with Temozolomide for Patients with Recurrent High-grade Astrocytomas
  2. Wu, Jing; Yuan, Ying; Long-Priel,Debra; Fink,Dani; Peer, Cody J.; Sissung, Tristan M.; Su, Yu-Ting; Pang, Ying; Yu, Guangyang; Butler, Madison K.; Mendoza, Tito R.; Vera, Elizabeth; Ahmad, Salman; Bryla, Christine; Lindsley, Matthew; Grajkowska, Ewa; Mentges, Kelly; Boris, Lisa; Antony, Ramya; Garren, Nancy; Siegel, Christine; Lollo, Nicole; Cordova, Christine; Aboud, Orwa; Theeler, Brett J.; Burton, Eric M.; Penas-Prado, Marta; Leeper, Heather; Gonzales, Javier; Armstrong, Terri S.; Calvo, Katherine R.; Figg, William D.; Kuhns,Doug; Gallin, John; Gilbert, Mark R.
  3. Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 2021, Jun 15; 27(12): 3298-3306.
  1. 15.   HIV-1 Integrase Inhibitors with Modifications That Affect Their Potencies against Drug Resistant Integrase Mutants
  2. Smith,Steven; Zhao,Xue Zhi; Passos, Dario Oliveira; Pye, Valerie E.; Cherepanov, Peter; Lyumkis, Dmitry; Burke,Terrence; Hughes,Stephen
  3. ACS Infectious Diseases. 2021, Jun 11; 7(6): 1469-1482.
  1. 16.   Ultrasensitive detection and quantification of viral nucleic acids with raindance droplet digital PCR (ddPCR)
  2. Long, Samuel; Berkemeier,Brian
  3. Methods (San Diego, Calif.). 2021, May 03; 201: 49-64.
  1. 17.   Mini-Factor H Modulates Complement-Dependent IL-6 and IL-10 Release in an Immune Cell Culture (PBMC) Model: Potential Benefits Against Cytokine Storm
  2. Kozma, Gergely Tibor; Mészáros, Tamás; Bakos, Tamás; Hennies, Mark; Bencze, Dániel; Uzonyi, Barbara; Gyorffy, Balázs; Cedrone,Edward; Dobrovolskaia,Marina; Józsi, Mihály; Szebeni, János
  3. Frontiers in Immunology. 2021, Apr 28; 12: 642860.
  1. 18.   Dabrafenib and Trametinib in Patients With Tumors With BRAFV600E Mutations: Results of the NCI-MATCH Trial Subprotocol H
  2. Salama, April K S; Li, Shuli; Macrae, Erin R; Park, Jong-In; Mitchell, Edith P; Zwiebel, James A; Chen, Helen X; Gray, Robert J; McShane, Lisa M; Rubinstein, Larry V; Patton, David; Williams,Mickey; Hamilton, Stanley R; Armstrong, Deborah K; Conley, Barbara A; Arteaga, Carlos L; Harris, Lyndsay N; O'Dwyer, Peter J; Chen, Alice P; Flaherty, Keith T
  3. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2020, NOV 20; 38(33): JCO2000762.
  1. 19.   Molecular Landscape and Actionable Alterations in a Genomically Guided Cancer Clinical Trial: National Cancer Institute Molecular Analysis for Therapy Choice (NCI-MATCH)
  2. Flaherty, Keith T; Gray, Robert J; Chen, Alice P; Li, Shuli; McShane, Lisa M; Patton, David; Hamilton, Stanley R; Williams,Mickey; Iafrate, A John; Sklar, Jeffrey; Mitchell, Edith P; Harris, Lyndsay N; Takebe, Naoko; Sims,David; Coffey,Brent; Fu,Tony; Routbort, Mark; Zwiebel, James A; Rubinstein, Larry V; Little, Richard F; Arteaga, Carlos L; Comis, Robert; Abrams, Jeffrey S; O'Dwyer, Peter J; Conley, Barbara A
  3. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2020, NOV 20; 38(33): pii: JCO1903010.
  1. 20.   Suberitamides A-C, Aryl Alkaloids from a Pseudosuberites sp. Marine Sponge that Inhibit Cbl-b Ubiquitin Ligase Activity
  2. Kim,Chang-Kwon; Wang,Dongdong; Wilson,Brice; Saurí, Josep; Voeller, Donna; Lipkowitz, Stanley; O'Keefe,Barry; Gustafson,Kirk
  3. Marine drugs. 2020, NOV; 18(11): pii: E536.
  1. 21.   The LTB4-BLT1 axis regulates actomyosin and beta(2)-integrin dynamics during neutrophil extravasation
  2. Subramanian, Bhagawat C.; Melis, Nicolas; Chen, Desu; Wang, Weiye; Gallardo,Devorah; Weigert, Roberto; Parent, Carole A.
  3. JOURNAL OF CELL BIOLOGY. 2020, OCT 5; 219(10):
  1. 22.   Nuclear Import of the HIV-1 Core Precedes Reverse Transcription and Uncoating
  2. Selyutina, Anastasia; Persaud, Mirjana; Lee,Kyeongeun; KewalRamani,Vineet; Diaz-Griffero, Felipe
  3. Cell reports. 2020, Sep 29; 32(13): 108201.
  1. 23.   Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors
  2. Oliva, Paola; Romagnoli, Romeo; Manfredini, Stefano; Brancale, Andrea; Ferla, Salvatore; Hamel,Ernest; Ronca, Roberto; Maccarinelli, Federica; Giacomini, Arianna; Rruga, Fatlum; Mariotto, Elena; Viola, Giampietro; Bortolozzi, Roberta
  3. European journal of medicinal chemistry. 2020, AUG 15; 200: 112448.
  1. 24.   Nucleotide-Specific Autoinhibition of Full-Length K-Ras4B Identified by Extensive Conformational Sampling
  2. Dudas, Balint; Merzel, Franci; Jang,Hyunbum; Nussinov,Ruth; Perahia, David; Balog, Erika
  3. Frontiers in molecular biosciences. 2020, JUL 10; 7: 145.
  1. 25.   Interaction of diazonamide a with tubulin
  2. Bai,Ruoli; Cruz-Monserrate, Zobeida; Fenical, William; Pettit, George R; Hamel,Ernest
  3. Archives of biochemistry and biophysics. 2020, FEB 15; 680: 108217.
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