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  1. 1.   The Cytokine Receptor IL-7Ra Impairs IL-2 Receptor Signaling and Constrains the In Vitro Differentiation of Foxp3+ Treg Cells
  2. Waickman, Adam T; Keller, Hilary R; Kim, Tae-Hyoun; Luckey, Megan A; Tai, Xuguang; Hong, Changwan; Molina-París, Carmen; Walsh,Scott; Park, Jung-Hyun
  3. iScience. 2020, AUG 21; 23(8): 101421.
  1. 2.   A fully human anti-IL-7Ra antibody promotes antitumor activity against T-cell acute lymphoblastic leukemia
  2. Akkapeddi, Padma; Fragoso, Rita; Hixon, Julie; Ramalho, Ana Sofia; Oliveira, Mariana L; Carvalho, Tânia; Gloger, Andreas; Matasci, Mattia; Corzana, Francisco; Durum, Scott; Neri, Dario; Bernardes, Gonçalo J L; Barata, João T
  3. Leukemia. 2019, SEP; 33(9): 2155-2168.
  1. 3.   Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia
  2. Zenatti, P. P.; Ribeiro, D.; Li, W. Q.; Zuurbier, L.; Silva, M. C.; Paganin, M.; Tritapoe, J.; Hixon, J. A.; Silveira, A. B.; Cardoso, B. A.; Sarmento, L. M.; Correia, N.; Toribio, M. L.; Kobarg, J.; Horstmann, M.; Pieters, R.; Brandalise, S. R.; Ferrando, A. A.; Meijerink, J. P.; Durum, S. K.; Yunes, J. A.; Barata, J. T.
  3. Nature Genetics. 2011, Oct; 43(10): 932-U31.
  1. 4.   Decreases in IL-7 levels during antiretroviral treatment of HIV infection suggest a primary mechanism of receptor-mediated clearance
  2. Hodge, J. N.; Srinivasula, S.; Hu, Z. H.; Read, S. W.; Porter, B. O.; Kim, I.; Mican, J. M.; Paik, C.; DeGrange, P.; Di Mascio, M.; Sereti, I.
  3. Blood. 2011, Sep; 118(12): 3244-3253.
  1. 5.   HIV-1 viruses detected during episodic blips following interleukin-7 administration are similar to the viruses present before and after interleukin-7 therapy
  2. Imamichi, H.; DeGray, G.; Asmuth, D. M.; Fischl, M. A.; Landay, A. L.; Lederman, M. M.; Sereti, I.
  3. Aids. 2011, Jan; 25(2): 159-164.
  1. 6.   Increased CD4(+) T Cell Levels during IL-7 Administration of Antiretroviral Therapy-Treated Simian Immunodeficiency Virus-Positive Macaques Are Not Dependent on Strong Proliferative Responses
  2. Leone, A.; Rohankhedkar, M.; Okoye, A.; Legasse, A.; Axthelm, M. K.; Villinger, F.; Piatak, M.; Lifson, J. D.; Assouline, B.; Morre, M.; Picker, L. J.; Sodora, D. L.
  3. Journal of Immunology. 2010, Aug; 185(3): 1650-1659.
  1. 7.   Immunologic and Virologic Events in Early HIV Infection Predict Subsequent Rate of Progression
  2. Ganesan, A.; Chattopadhyay, P. K.; Brodie, T. M.; Qin, J.; Gu, W. J.; Mascola, J. R.; Michael, N. L.; Follmann, D. A.; Roederer, M.; Infect Dis Clinical Res Program, H. I.
  3. Journal of Infectious Diseases. 2010, Jan; 201(2): 272-284.
  1. 8.   Visualization and identification of IL-7 producing cells in reporter mice
  2. Mazzucchelli, R. I.; Warming, S.; Lawrence, S. M.; Ishii, M.; Abshari, M.; Washington, A. V.; Feigenbaum, L.; Warner, A. C.; Sims, D. J.; Li, W. Q.; Hixon, J. A.; Gray, D. H.; Rich, B. E.; Morrow, M.; Anver, M. R.; Cherry, J.; Naf, D.; Sternberg, L. R.; McVicar, D. W.; Farr, A. G.; Germain, R. N.; Rogers, K.; Jenkins, N. A.; Copeland, N. G.; Durum, S. K.
  3. Plos One. 2009 4(11): e7637.
  1. 9.   Live from the Liver: Hepatocyte IL-7
  2. Durum, S. K.; Mazzucchelli, R. I.
  3. Immunity. 2009 30(3): 320-321.
  1. 10.   Development of regulatory T cells requires IL-7R alpha stimulation by IL-7 or TSLP
  2. Mazzucchelli, R.; Hixon, J. A.; Spolski, R.; Chen, X.; Li, W. Q.; Hall, V. L.; Willette-Brown, J.; Hurwitz, A. A.; Leonard, W. J.; Durum, S. K.
  3. Blood. 2008, Oct 15; 112(8): 3283-3292.
  1. 11.   IL-7 induces myelopoiesis and erythropoiesis
  2. Aiello, F. B.; Keller, J. R.; Klarmann, K. D.; Dranoff, G.; Mazzucchelli, R.; Durum, S. K.
  3. Journal of Immunology. 2007, Feb; 178(3): 1553-1563.
  1. 12.   Role of the intracellular domain of IL-7 receptor in T cell development
  2. Jiang, Q.; Huang, J.; Li, W. Q.; Cavinato, T.; Keller, J. R.; Durum, S. K.
  3. Journal of Immunology. 2007, Jan; 178(1): 228-234.
  1. 13.   Delayed sample processing leads to marked decreases in measured plasma IL-7 levels
  2. Read, S. W.; Rupert, A.; Stevens, R.; O'Shea, A.; Sereti, I.
  3. Jaids-Journal of Acquired Immune Deficiency Syndromes. 2006, Aug; 42(4): 511-512.
  1. 14.   Decreased CD127 expression on T cells in HIV-1-infected adults receiving antiretroviral therapy with or without intermittent IL-2 therapy
  2. Read, S. W.; Higgins, J.; Metcalf, J. A.; Stevens, R. A.; Rupert, A.; Nason, M. C.; Lane, H. C.; Sereti, I.
  3. Jaids-Journal of Acquired Immune Deficiency Syndromes. 2006, Aug; 42(5): 537-544.
  1. 15.   Cell cycling through Cdc25A - Transducer of cytokine proliferative signals
  2. Kittipatarin, C.; Li, W. Q.; Bulavin, D. V.; Durum, S. K.; Khaled, A. R.
  3. Cell Cycle. 2006, May; 5(9): 907-912.
  1. 16.   IL-7 promotes T cell proliferation through destabilization of p27(Kip1)
  2. Li, W. Q.; Jiang, Q.; Aleem, E.; Kaldis, P.; Khaled, A. R.; Durum, S. K.
  3. Journal of Experimental Medicine. 2006, Mar; 203(3): 573-582.
  1. 17.   Stat5a/b are essential for normal lymphoid development and differentiation
  2. Yao, Z. J.; Cui, Y. Z.; Watford, W. T.; Bream, J. H.; Yamaoka, K.; Hissong, B. D.; Li, D.; Durum, S. K.; Jiang, Q. O.; Bhandoola, A.; Hennighausen, L.; O'Shea, J. J.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2006, JAN 24; 103(4): 1000-1005.
  1. 18.   Cytokine signal transduction is suppressed in preselection double-positive thymocytes and restored by positive selection
  2. Yu, Q.; Park, J. H.; Doan, L. L.; Erman, B.; Feigenbaum, L.; Singer, A.
  3. Journal of Experimental Medicine. 2006, JAN 23; 203(1): 165-175.
  1. 19.   Retroviral transduction of IL-7R alpha into IL-7R alpha(-/-) bone marrow progenitors: correction of lymphoid deficiency and induction of neutrophilia
  2. Jiang, Q.; Li, W. Q.; Aiello, F. B.; Klarmann, K.; Keller, J. R.; Durum, S. K.
  3. Gene Therapy. 2005, DEC; 12(24): 1761-1768.
  1. 20.   Cytokine-driven cell cycling is mediated through Cdc25A
  2. Khaled, A. R.; Bulavin, D. V.; Kittipatarin, C.; Li, W. Q.; Alvarez, M.; Kim, K.; Young, H. A.; Fornace, A. J.; Durum, S. K.
  3. Journal of Cell Biology. 2005, JUN 6; 169(5): 755-763.
  1. 21.   Effects of lymphocyte isolation and timing of processing on detection of CD127 expression on T cells in human immunodeficiency virus-infected patients
  2. Higgins, J.; Metcalf, J. A.; Stevens, R. A.; Baseler, M.; Nason, M. C.; Lane, H. C.; Sereti, I.
  3. Clinical and Diagnostic Laboratory Immunology. 2005, JAN; 12(1): 228-230.
  1. 22.   IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and ROR gamma t: Impact on thymocyte development
  2. Yu, Q.; Erman, B.; Park, J. H.; Feigenbaum, L.; Singer, A.
  3. Journal of Experimental Medicine. 2004, SEP 20; 200(6): 797-803.
  1. 23.   IL-7 induces tyrosine phosphorylation of clathrin heavy chain
  2. Jiang, Q.; Benbernou, N.; Chertov, O.; Khaled, A. R.; Wooters, J.; Durum, S. K.
  3. Cellular Signalling. 2004 16(2): 281-286.
  1. 24.   Host conditioning is a primary determinant in modulating the effect of IL-7 on murine graft-versus-host disease
  2. Gendelman, M.; Hecht, T.; Logan, B.; Vodanovic-Jankovic, S.; Komorowski, R.; Drobyski, W. R.
  3. Journal of Immunology. 2004 172(5): 3328-3336.
  1. 25.   Effects of IL-7 and dexamethasone: Induction of CD25, the high affinity IL-2 receptor, on human CD4(+) cells
  2. Chung, I. Y.; Dong, H. F.; Zhang, X.; Hassanein, N. M. A.; Howard, O. M. Z.; Oppenheim, J. J.; Chen, X.
  3. Cellular Immunology. 2004, NOV-DEC; 232(1-2): 57-63.
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