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  1. 1.   A new genre of fluorescence recovery assay to evaluate polo-like kinase 1 ATP-competitive inhibitors
  2. Tsuji, Kohei; Hymel, David; Burke,Terrence
  3. Analytical methods : advancing methods and applications. 2020, Sep 28; 12(36): 4418-4421.
  1. 2.   Prolonged mitosis results in structurally aberrant and over-elongated centrioles
  2. Kong,Dong; Sahabandu, Natalie; Sullenberger,Catherine; Vásquez-Limeta, Alejandra; Luvsanjav,Delgermaa; Lukasik,Kimberly; Loncarek,Jadranka
  3. The Journal of cell biology. 2020, Jun 01; 219(6): pii: 151638.
  1. 3.   Modulation of Target Antigen Density Improves CAR T-cell Functionality and Persistence
  2. Ramakrishna, Sneha; Highfill, Steven L.; Walsh, Zachary; Nguyen, Sang M.; Lei, Haiyan; Shern, Jack F.; Qin, Haiying; Kraft, Ira L.; Stetler-Stevenson, Maryalice; Yuan, Constance M.; Hwang, Jennifer D.; Feng,Yang; Zhu, Zhongyu; Dimitrov, Dimiter; Shah, Nirali N.; Fry, Terry J.
  3. CLINICAL CANCER RESEARCH. 2019, Sep 1; 25(17): 5329-5341.
  1. 4.   Structures of the PKA RI alpha Holoenzyme with the FLHCC Driver J-PKAc alpha or Wild-Type PKAc alpha
  2. Cao,Baohua; Lu, Tsan-Wen; Martinez Fiesco,Juliana; Tomasini, Michael; Fan,Lixin; Simon, Sanford M.; Taylor, Susan S.; Zhang,Ping
  3. Structure (London, England : 1993). 2019, MAY 7; 27(5): 816-+.
  1. 5.   Review: Precision medicine and driver mutations: Computational methods, functional assays and conformational principles for interpreting cancer drivers
  2. Nussinov,Ruth; Jang,Hyunbum; Tsai,Chung-Jung; Cheng, Feixiong
  3. PLoS computational biology. 2019, Mar; 15(3):
  1. 6.   alpha-Arylidene Diacylglycerol-Lactones (DAG-Lactones) as Selective Ras Guanine-Releasing Protein 3 (RasGRP3) Ligands
  2. Ann, Jihyae; Czikora, Agnes; Saini, Amandeep S.; Zhou, Xiaoling; Mitchell, Gary A.; Lewin, Nancy E.; Peach, Megan; Blumberg, Peter M.; Lee, Jeewoo
  3. Journal of Medicinal Chemistry. 2018, Jul 26; 61(14): 6261-6276.
  1. 7.   Crosstalk between PKC alpha and PI3K/AKT Signaling Is Tumor Suppressive in the Endometrium
  2. Hsu, Alice; Lum, Michelle A.; Shim, Kang-Sup; Frederick, Peter J.; Morrison, Carl D.; Chen, Baojiang; Lele, Subodh M.; Sheinin, Yuri M.; Daikoku, Takiko; Dey, Sudhansu K.; Leone, Gustavo; Black, Adrian R.; Black, Jennifer D.
  3. CELL REPORTS. 2018, Jul 17; 24(3): 655-669.
  1. 8.   IKK alpha represses a network of inflammation and proliferation pathways and elevates c-Myc antagonists and differentiation in a dose-dependent manner in the skin
  2. Liu, B.; Willette-Brown, J.; Liu, S.; Chen, X.; Fischer, S. M.; Hu, Y.
  3. Cell Death and Differentiation. 2011, Dec; 18(12): 1854-1864.
  1. 9.   Ceramide Transfer Protein and Cancer
  2. Scheffer, L.; Raghavendra, P. R.; Ma, J. J.; Acharya, J. K.
  3. Anti-cancer agents in medicinal chemistry. 2011, Nov; 11(9): 904-910.
  1. 11.   N-Methyl-Substituted Fluorescent DAG-Indololactone Isomers Exhibit Dramatic Differences in Membrane Interactions and Biological Activity
  2. Gal, N.; Kolusheva, S.; Kedei, N.; Telek, A.; Naeem, T. A.; Lewin, N. E.; Lim, L.; Mannan, P.; Garfield, S. H.; El Kazzouli, S.; Sigano, D. M.; Marquez, V. E.; Blumberg, P. M.; Jelinek, R.
  3. Chembiochem. 2011, Oct; 12(15): 2331-2340.
  1. 12.   Serendipitous alkylation of a Plk1 ligand uncovers a new binding channel
  2. Liu, F.; Park, J. E.; Qian, W. J.; Lim, D.; Graber, M.; Berg, T.; Yaffe, M. B.; Lee, K. S.; Burke, T. R.
  3. Nature Chemical Biology. 2011, Sep; 7(9): 595-601.
  1. 13.   Dopaminergic Neuronal Loss, Reduced Neurite Complexity and Autophagic Abnormalities in Transgenic Mice Expressing G2019S Mutant LRRK2
  2. Ramonet, D.; Daher, J. P. L.; Lin, B. M.; Stafa, K.; Kim, J.; Banerjee, R.; Westerlund, M.; Pletnikova, O.; Glauser, L.; Yang, L. C.; Liu, Y.; Swing, D. A.; Beal, M. F.; Troncoso, J. C.; McCaffery, J. M.; Jenkins, N. A.; Copeland, N. G.; Galter, D.; Thomas, B.; Lee, M. K.; Dawson, T. M.; Dawson, V. L.; Moore, D. J.
  3. Plos One. 2011, Apr; 6(4):
  1. 14.   Combinatorial Tau Pseudophosphorylation MARKEDLY DIFFERENT REGULATORY EFFECTS ON MICROTUBULE ASSEMBLY AND DYNAMIC INSTABILITY THAN THE SUM OF THE INDIVIDUAL PARTS
  2. Kiris, E.; Ventimiglia, D.; Sargin, M. E.; Gaylord, M. R.; Altinok, A.; Rose, K.; Manjunath, B. S.; Jordan, M. A.; Wilson, L.; Feinstein, S. C.
  3. Journal of Biological Chemistry. 2011, Apr; 286(16): 14257-14270.
  1. 15.   Role of vascular K(ATP) channels in blood pressure variability after sinoaortic denervation in rats
  2. Yang, Z. W.; Li, D. J.; Liu, C.; Han, P.; Yang, Y. L.; Su, D. F.; Shen, F. M.
  3. Acta Pharmacologica Sinica. 2011, Feb; 32(2): 194-200.
  1. 16.   Pharmacologic Modulation of Serine/Threonine Phosphorylation Highly Sensitizes PHEO in a MPC Cell and Mouse Model to Conventional Chemotherapy
  2. Martiniova, L.; Lu, J.; Chiang, J.; Bernardo, M.; Lonser, R.; Zhuang, Z. P.; Pacak, K.
  3. Plos One. 2011, Feb; 6(2): 8.
  1. 17.   Role of IKK alpha in skin squamous cell carcinomas
  2. Park, E. M.; Liu, B. G.; Xia, X. J.; Zhu, F.; Jami, W. B.; Hu, Y. L.
  3. Future Oncology. 2011, Jan; 7(1): 123-134.
  1. 18.   AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade
  2. Smith, F. D.; Langeberg, L. K.; Cellurale, C.; Pawson, T.; Morrison, D. K.; Davis, R. J.; Scott, J. D.
  3. Nature Cell Biology. 2010, Dec; 12(12): 1242-U287.
  1. 19.   Allosteric Regulation of Glycogen Synthase Kinase 3 beta: A Theoretical Study
  2. Buch, I.; Fishelovitch, D.; London, N.; Raveh, B.; Wolfson, H. J.; Nussinov, R.
  3. Biochemistry. 2010, Dec; 49(51): 10890-10901.
  1. 20.   Membrane-Surface Anchoring of Charged Diacylglycerol-Lactones Correlates with Biological Activities
  2. Raifman, O.; Kolusheva, S.; El Kazzouli, S.; Sigano, D. M.; Kedei, N.; Lewin, N. E.; Lopez-Nicolas, R.; Ortiz-Espin, A.; Gomez-Fernandez, J. C.; Blumberg, P. M.; Marquez, V. E.; Corbalan-Garcia, S.; Jelinek, R.
  3. Chembiochem. 2010, Sep; 11(14): 2003-2009.
  1. 21.   Implications for Gene Therapy-Limiting Expression of IL-2R gamma(c) Delineate Differences in Signaling Thresholds Required for Lymphocyte Development and Maintenance
  2. Orr, S. J.; Roessler, S.; Quigley, L.; Chan, T.; Ford, J. W.; O'Connor, G. M.; McVicar, D. W.
  3. Journal of Immunology. 2010, Aug; 185(3): 1393-1403.
  1. 22.   Molecular Modeling, Total Synthesis, and Biological Evaluations of C9-Deoxy Bryostatin 1
  2. Keck, G. E.; Poudel, Y. B.; Rudra, A.; Stephens, J. C.; Kedei, N.; Lewin, N. E.; Peach, M. L.; Blumberg, P. M.
  3. Angewandte Chemie-International Edition. 2010, Jun 21; 49(27): 4580-4584.
  1. 23.   Probing Binding Modes of Small Molecule Inhibitors to the Polo-Box Domain of Human Polo-like Kinase 1
  2. Liao, C. Z.; Park, J. E.; Bang, J. K.; Nicklaus, M. C.; Lee, K. S.
  3. Acs Medicinal Chemistry Letters. 2010, Jun; 1(3): 110-114.
  1. 24.   Reduction of IKK alpha Expression Promotes Chronic Ultraviolet B Exposure-Induced Skin Inflammation and Carcinogenesis
  2. Xia, X. J.; Park, E.; Liu, B. G.; Willette-Brown, J.; Gong, W. H.; Wang, J. M.; Mitchell, D.; Fischer, S. M.; Hu, Y. L.
  3. American Journal of Pathology. 2010, May; 176(5): 2500-2508.
  1. 25.   Membrane anchoring of diacylglycerol lactones substituted with rigid hydrophobic acyl domains correlates with biological activities
  2. Raifman, O.; Kolusheva, S.; Comin, M. J.; Kedei, N.; Lewin, N. E.; Blumberg, P. M.; Marquez, V. E.; Jelinek, R.
  3. Febs Journal. 2010, Jan; 277(1): 233-243.
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