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  1. 1.   Four New Pregnane-10,2-carbolactones from an Epipolasis sp. Marine Sponge
  2. Kang, Unwoo; Wang,Dongdong; Bokesch, Heidi R.; Gustafson,Kirk
  3. Chemical & pharmaceutical bulletin. 2021, Jan; 69(1): 48-51.
  1. 2.   Review of bioactive secondary metabolites from marine bryozoans in the progress of new drugs discovery
  2. Tian, Xiang Rong; Tang, Hai Feng; Tian, Xiao Lin; Hu, Jia Jun; Huang, Li Li; Gustafson, Kirk
  3. Future medicinal chemistry. 2018, Jun; 10(12): 1497-1514.
  1. 3.   Dietary lignan and proanthocyanidin consumption and colorectal adenoma recurrence in the Polyp Prevention Trial
  2. Bobe, G.; Murphy, G.; Albert, P. S.; Sansbury, L. B.; Lanza, E.; Schatzkin, A.; Cross, A. J.
  3. International Journal of Cancer. 2012, Apr; 130(7): 1649-1659.
  1. 4.   Quantification of irinotecan, SN38, and SN38G in human and porcine plasma by ultra high-performance liquid chromatography-tandem mass spectrometry and its application to hepatic chemoembolization
  2. Chen, X. H.; Peer, C. J.; Alfaro, R.; Tian, T.; Spencer, S. D.; Figg, W. D.
  3. Journal of Pharmaceutical and Biomedical Analysis. 2012, Mar; 62: 140-148.
  1. 5.   Effects of ascorbic acid on carcinogenicity and acute toxicity of nickel subsulfide, and on tumor transplants growth in gulonolactone oxidase knock-out mice and wild-type C57BL mice
  2. Kasprzak, K. S.; Diwan, B. A.; Kaczmarek, M. Z.; Logsdon, D. L.; Fivash, M. J.; Salnikow, K.
  3. Toxicology and Applied Pharmacology. 2011, Nov; 257(1): 32-37.
  1. 6.   N-Methyl-Substituted Fluorescent DAG-Indololactone Isomers Exhibit Dramatic Differences in Membrane Interactions and Biological Activity
  2. Gal, N.; Kolusheva, S.; Kedei, N.; Telek, A.; Naeem, T. A.; Lewin, N. E.; Lim, L.; Mannan, P.; Garfield, S. H.; El Kazzouli, S.; Sigano, D. M.; Marquez, V. E.; Blumberg, P. M.; Jelinek, R.
  3. Chembiochem. 2011, Oct; 12(15): 2331-2340.
  1. 7.   Inhibitors of the Oncogenic Transcription Factor AP-1 from Podocarpus latifolius
  2. Devkota, K. P.; Ratnayake, R.; Colburn, N. H.; Wilson, J. A.; Henrich, C. J.; McMahon, J. B.; Beutler, J. A.
  3. Journal of Natural Products. 2011, Mar; 74(3): 374-377.
  1. 8.   Membrane-Surface Anchoring of Charged Diacylglycerol-Lactones Correlates with Biological Activities
  2. Raifman, O.; Kolusheva, S.; El Kazzouli, S.; Sigano, D. M.; Kedei, N.; Lewin, N. E.; Lopez-Nicolas, R.; Ortiz-Espin, A.; Gomez-Fernandez, J. C.; Blumberg, P. M.; Marquez, V. E.; Corbalan-Garcia, S.; Jelinek, R.
  3. Chembiochem. 2010, Sep; 11(14): 2003-2009.
  1. 9.   Isolation, Structural Elucidation, and Absolute Stereochemistry of Enigmazole A, a Cytotoxic Phosphomacrolide from the Papua New Guinea Marine Sponge Cinachyrella enigmatica
  2. Oku, N.; Takada, K.; Fuller, R. W.; Wilson, J. A.; Peach, M. L.; Pannell, L. K.; McMahon, J. B.; Gustafson, K. R.
  3. Journal of the American Chemical Society. 2010, Aug; 132(30): 10278-10285.
  1. 10.   Membrane anchoring of diacylglycerol lactones substituted with rigid hydrophobic acyl domains correlates with biological activities
  2. Raifman, O.; Kolusheva, S.; Comin, M. J.; Kedei, N.; Lewin, N. E.; Blumberg, P. M.; Marquez, V. E.; Jelinek, R.
  3. Febs Journal. 2010, Jan; 277(1): 233-243.
  1. 11.   Natural product scaffolds as leads-to drugs
  2. Newman, D. J.; Cragg, G. M.
  3. Future Medicinal Chemistry. 2009, Nov; 1(8): 1415-1427.
  1. 12.   Inhibitors of the NF-kappaB activation pathway from Cryptocarya rugulosa
  2. Meragelman, T. L.; Scudiero, D. A.; Davis, R. E.; Staudt, L. M.; McCloud, T. G.; Cardellina, J. H. 2nd.; Shoemaker, R. H.
  3. Journal of Natural Products. 2009, Mar 27; 72(3): 336-9.
  1. 13.   Ceramides: Branched alkyl chains in the sphingolipid siblings of diacylglycerol improve biological potency
  2. Kang, J. H.; Garg, H.; Sigano, D. M.; Francella, N.; Blumenthal, R.; Marquez, V. E.
  3. Bioorganic & Medicinal Chemistry. 2009 17(4): 1498-1505.
  1. 14.   Antineoplastic Agents. 565. Synthesis of Combretastatin D-2 Phosphate and Dihydro-combretastatin D-2
  2. Pettit, G. R.; Quistorf, P. D.; Fry, J. A.; Herald, D. L.; Hamel, E.; Chapuis, J. C.
  3. Journal of Natural Products. 2009 72(5): 876-883.
  1. 15.   Lipid-Modulated Pharmacophore Nanorods Assembled at the Air/Water Interface
  2. Philosof-Mazor, L.; Volinsky, R.; Jopp, J.; Blumberg, P.; Rapaport, H.; Marquez, V. E.; Jelinek, R.
  3. Chemphyschem. 2009 10(15): 2615-2619.
  1. 16.   Conformationally constrained analogues of diacylglycerol. 29. Cells sort diacylglycerol-lactone chemical zip codes to produce diverse and selective biological activities
  2. Duan, D.; Sigano, D. M.; Kelley, J. A.; Lai, C. C.; Lewin, N. E.; Kedei, N.; Peach, M. L.; Lee, J.; Abeyweera, T. P.; Rotenberg, S. A.; Kim, H.; Kim, Y. H.; El Kazzouli, S.; Chung, J. U.; Young, H. A.; Young, M. R.; Baker, A.; Colburn, N. H.
  3. Journal of Medicinal Chemistry. 2008 51(17): 5198-5220.
  1. 17.   Conformationally constrained analogues of diacylglycerol. 30. An investigation of diacylglycerol-lactones containing heteroaryl groups reveals compounds with high selectivity for Ras guanyl nucleotide-releasing proteins
  2. El Kazzouli, S.; Lewin, N. E.; Blumberg, P. M.; Marquez, V. E.
  3. Journal of Medicinal Chemistry. 2008 51(17): 5371-5386.
  1. 18.   Self-assembly and lipid interactions of diacylglycerol lactone derivatives studied at the air/water interface
  2. Philosof-Mazor, L.; Volinsky, R.; Comin, M. J.; Lewin, N. E.; Kedei, N.; Blumberg, P. M.; Marquez, V. E.; Jelinek, R.
  3. Langmuir. 2008 24(19): 11043-11052.
  1. 19.   Conformationally constrained analogues of diacylglycerol (DAG). 28. DAG-dioxolanones reveal a new additional interaction site in the C1b domain of PKC delta
  2. Choi, Y.; Pu, Y.; Peach, M. L.; Kang, J. H.; Lewin, N. E.; Sigano, D. M.; Garfield, S. H.; Blumberg, P. M.; Marquez, V. E.
  3. Journal of Medicinal Chemistry. 2007, Jul; 50(15): 3465-3481.
  1. 20.   Selective leukemic-cell killing by a novel functional class of thalidomide analogs
  2. Ge, Y.; Montano, I.; Rustici, G.; Freebern, W. J.; Haggerty, C. M.; Cui, W. W.; Ponciano-Jackson, D.; Chandramouli, G. V. R.; Gardner, E. R.; Figg, W. D.; Abu-Asab, M.; Tsokos, M.; Jackson, S. H.; Gardner, K.
  3. Blood. 2006, Dec; 108(13): 4126-4135.
  1. 21.   Natural products from marine invertebrates and microbes as modulators of antitumor targets
  2. Newman, D. J.; Cragg, G. M.
  3. Current Drug Targets. 2006, MAR; 7(3): 279-304.
  1. 22.   Inhibition of transcription factor NF-kappa B signaling proteins IKK beta and p65 through specific cysteine residues by epoxyquinone A monomer: Correlation with its anti-cancer cell growth activity
  2. Liang, M. C.; Bardhan, S.; Pace, E. A.; Rosman, D.; Beutler, J. A.; Porco, J. A.; Gilmore, T. D.
  3. Biochemical Pharmacology. 2006, FEB 28; 71(5): 634-645.
  1. 23.   The search for novel drug leads for predominately antitumor therapies by utilizing mother nature's pharmacophoric libraries
  2. Kingston, D. G. I.; Newman, D. J.
  3. Current Opinion in Drug Discovery & Development. 2005, MAR; 8(2): 207-227.
  1. 24.   Conformationally constrained analogues of diacylglycerol (DAG). 23. Hydrophobic ligand-protein interactions versus ligand-lipid interactions of DAG-lactones with protein kinase C (PK-C)
  2. Tamamura, H.; Sigano, D. M.; Lewin, N. E.; Peach, M. L.; Nicklaus, M. C.; Blumberg, P. M.; Marquez, V. E.
  3. Journal of Medicinal Chemistry. 2004, SEP 23; 47(20): 4858-4864.
  1. 25.   The discovery of protein kinase C (PK-C) isozyme: Specific ligands driven by a solid-phase combinatorial synthesis of diacylglycerol-lactones (DAG-lactones)
  2. Duan, D. H.; Peach, M. L.; Lai, C. C.; Lewin, N. E.; Kelley, J. A.; Blumberg, P. M.; Marquez, V. E.
  3. Abstracts of Papers of the American Chemical Society. 2004, AUG 22; 228(Part 1): 177-MEDI, Abstract U939-177-MEDI, Abstract U939.
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