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  1. 1.   4 '-C-Methyl-2 '-Deoxyadenosine and 4 '-C-Ethyl-2 '-Deoxyadenosine Inhibit HIV-1 Replication
  2. Vu, B. C.; Boyer, P. L.; Siddiqui, M. A.; Marquez, V. E.; Hughes, S. H.
  3. Antimicrobial Agents and Chemotherapy. 2011, May; 55(5): 2379-2389.
  1. 2.   Progressive Mitochondrial Compromise in Brains and Livers of Primates Exposed In Utero to Nucleoside Reverse Transcriptase Inhibitors (NRTIs)
  2. Divi, R. L.; Einem, T. L.; Fletcher, S. L. L.; Shockley, M. E.; Kuo, M. M.; St Claire, M. C.; Cook, A.; Nagashima, K.; Harbaugh, S. W.; Harbaugh, J. W.; Poirier, M. C.
  3. Toxicological Sciences. 2010, Nov; 118(1): 191-201.
  1. 3.   Evaluation of the Pathogenesis of Decreasing CD4(+) T Cell Counts in Human Immunodeficiency Virus Type 1-Infected Patients Receiving Successfully Suppressive Antiretroviral Therapy
  2. Nies-Kraske, E.; Schacker, T. W.; Condoluci, D.; Orenstein, J.; Brenchley, J.; Fox, C.; Daucher, M.; Dewar, R.; Urban, E.; Hill, B.; Guenaga, J.; Hoover, S.; Maldarelli, F.; Hallahan, C. W.; Horn, J.; Kottilil, S.; Chun, T. W.; Folino, M.; Palmer, S.
  3. Journal of Infectious Diseases. 2009 199(11): 1648-1656.
  1. 4.   Erythrocebus patas monkey offspring exposed perinatally to NRTIs sustain skeletal muscle mitochondrial compromise at birth and at 1 year of age
  2. Divi, R. L.; Leonard, S. L.; Walker, B. L.; Kuo, M. M.; Shockley, M. E.; St Claire, M. C.; Nagashima, K.; Harbaugh, S. W.; Harbaugh, J. W.; Poirier, M. C.
  3. Toxicological Sciences. 2007, Sep; 99(1): 203-213.
  1. 5.   Transplacentally exposed human and monkey newborn infants show similar evidence of nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity
  2. Divi, R. L.; Leonard, S. L.; Kuo, M. M.; Nagashima, K.; Thamire, C.; St Claire, M. C.; Wade, N. A.; Walker, V. E.; Poirier, M. C.
  3. Environmental and Molecular Mutagenesis. 2007, Apr-May; 48(3-4): 201-209.
  1. 6.   Infectious transmission and replication of human T-cell leukemia virus type 1
  2. Derse, D.; Heidecker, G.; Mitchell, M.; Hill, S.; Lloyd, P.; Princler, G.
  3. Frontiers in Bioscience. 2004, SEP 1; 9: 2495-2499.
  1. 7.   Mitochondrial damage and DNA depletion in cord blood and umbilical cord from infants exposed in utero to Combivir
  2. Divi, R. L.; Walker, V. E.; Wade, N. A.; Nagashima, K.; Seilkopf, S. K.; Adams, M. E.; Nesel, C. J.; O'Neill, J. P.; Abrams, E. J.; Poirier, M. C.
  3. Aids. 2004 18(7): 1013-1021.
  1. 8.   Mitochondrial toxicity in fetal Erythrocebus patas monkeys exposed transplacentally to zidovudine plus lamivudine
  2. Gerschenson, M.; Nguyen, V.; Ewings, E. L.; Ceresa, A.; Shaw, J. A.; St Claire, M. C.; Nagashima, K.; Harbaugh, S. W.; Harbaugh, J. W.; Olivero, O. A.; Divi, R. L.; Albert, P. S.; Poirier, M. C.
  3. Aids Research and Human Retroviruses. 2004 20(1): 91-100.
  1. 9.   Colinearity of reverse transcriptase inhibitor resistance mutations detected by population-based sequencing
  2. Gonzales, M. J.; Johnson, E.; Dupnik, K. M.; Imamichi, T.; Shafer, R. W.
  3. Jaids-Journal of Acquired Immune Deficiency Syndromes. 2003 34(4): 398-402.
  1. 10.   Susceptibility of human T cell leukemia virus type I to nucleoside reverse transcriptase inhibitors
  2. Hill, S. A.; Lloyd, P. A.; McDonald, S.; Wykoff, J.; Derse, D.
  3. Journal of Infectious Diseases. 2003 188(3): 424-427.
  1. 11.   Tenofovir, adefovir, and zidovudine susceptibilities of primary human immunodeficiency virus type 1 isolates with non-B subtypes or nucleoside resistance
  2. Palmer, S.; Margot, N.; Gilbert, H.; Shaw, N.; Buckheit, R.; Miller, M.
  3. Aids Research and Human Retroviruses. 2001 17(12): 1167-1173.
  1. 12.   Wild-type and YMDD mutant murine leukemia virus reverse transcriptases are resistant to 2 ',3 '-dideoxy-3 '-thiacytidine
  2. Halvas, E. K.; Svarovskaia, E. S.; Freed, E. O.; Pathak, V. K.
  3. Journal of Virology. 2000 74(14): 6669-6674.
  1. 13.   Structures of Tyr188leu Mutant and Wild-Type Hiv-1 Reverse Transcriptase Complexed With the Non-Nucleoside Inhibitor Hby 097 - Inhibitor Flexibility Is a Useful Design Feature For Reducing Drug Resistance
  2. Hsiou, Y.; Das, K. Y.; Ding, J. P.; Clark, A. D.; Kleim, J. P.; Rosner, M.; Winkler, I.; Riess, G.; Hughes, S. H.; Arnold, E.
  3. Journal of Molecular Biology. 1998 284(2): 313-323.
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