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  1. 1.   Pharmacodynamic effects of the PARP inhibitor talazoparib (MDV3800, BMN 673) in patients with BRCA-mutated advanced solid tumors
  2. Mittra, Arjun; Coyne, Geraldine H O' Sullivan; Zlott, Jennifer; Kummar, Shivaani; Meehan, Robert; Rubinstein, Lawrence; Juwara,Lamin; Wilsker,Deborah; Ji,Jay; Miller,Brandon; Navas, Tony; Ferry-Galow,Katherine; Voth,Andrea; Chang,Ting-Chia; Jiwani,Shahanawaz; Parchment,Ralph; Doroshow, James H; Chen, Alice P
  3. Cancer Chemotherapy and Pharmacology. 2023, Nov 27;
  1. 2.   Dysregulation of Hepatitis B Virus Nucleocapsid Assembly in vitro by RNA-binding Small Ligands
  2. Patel, Nikesh; Abulwerdi, Fardokht; Fatehi, Farzad; Manfield, Iain; Le Grice,Stuart; Schneekloth,Jay; Twarock, Reidun; Stockley, Peter G
  3. Journal of Molecular Biology. 2022, Mar 24; 167557.
  1. 3.   Methylated Septin9 (mSEPT9): A promising blood-based biomarker for the detection and screening of early-onset colorectal cancer
  2. Loomans-Kropp, Holli A; Song,Yurong; Gala, Manish; Parikh, Aparna R; Van Seventer, Emily E; Alvarez, Rocio; Hitchins, Megan P; Shoemaker, Robert H; Umar, Asad
  3. Cancer Research Communications. 2022, Feb; 2(2): 90-98.
  1. 4.   Predicting Volume of Distribution in Humans: Performance of in silico Methods for A Large Set of Structurally Diverse Clinical Compounds
  2. Murad, Neha; Pasikanti, Kishore K; Madej,Benjamin; Minnich, Amanda; McComas, Juliet M; Crouch, Sabrinia; Polli, Joseph W; Weber, Andrew D
  3. Drug metabolism and disposition: the biological fate of chemicals. 2021, Feb 1; 49: 169-178.
  1. 5.   HIV Infected T Cells Can Proliferate in vivo Without Inducing Expression of the Integrated Provirus
  2. Musick,Andrew; Spindler,Jon; Boritz, Eli; Pérez, Liliana; Crespo-Vélez, Daniel; Patro,Sean; Sobolewski, Michele D; Bale,Michael; Reid, Carolyn; Keele,Brandon; Capoferri, Adam; Shao,Wei; Wiegand,Ann; Simonetti, Francesco R; Mellors, John W; Hughes,Stephen; Coffin, John M; Maldarelli,Frank; Kearney,Mary
  3. Frontiers in microbiology. 2019, OCT 1; 10: 2204.
  1. 6.   The chromosome 2p21 region harbors a complex genetic architecture for association with risk for renal cell carcinoma
  2. Han, S. S.; Yeager, M.; Moore, L. E.; Wei, M. H.; Pfeiffer, R.; Toure, O.; Purdue, M. P.; Johansson, M.; Scelo, G.; Chung, C. C.; Gaborieau, V.; Zaridze, D.; Schwartz, K.; Szeszenia-Dabrowska, N.; Davis, F.; Bencko, V.; Colt, J. S.; Janout, V.; Matveev, V.; Foretova, L.; Mates, D.; Navratilova, M.; Boffetta, P.; Berg, C. D.; Grubb, R. L.; Stevens, V. L.; Thun, M. J.; Diver, W. R.; Gapstur, S. M.; Albanes, D.; Weinstein, S. J.; Virtamo, J.; Burdett, L.; Brisuda, A.; McKay, J. D.; Fraumeni, J. F.; Chatterjee, N.; Rosenberg, P. S.; Rothman, N.; Brennan, P.; Chow, W. H.; Tucker, M. A.; Chanock, S. J.; Toro, J. R.
  3. Human Molecular Genetics. 2012, Mar; 21(5): 1190-1200.
  1. 7.   Characterization of feline hereditary retinal dystrophies using clinical, functional, structural and molecular genetic studies
  2. Narfstrom, K.; Raymond, M. M.; Seeliger, M.
  3. Veterinary Ophthalmology. 2011, Sep; 14: 30-36.
  1. 8.   Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3
  2. Purdue, M. P.; Johansson, M.; Zelenika, D.; Toro, J. R.; Scelo, G.; Moore, L. E.; Prokhortchouk, E.; Wu, X. F.; Kiemeney, L. A.; Gaborieau, V.; Jacobs, K. B.; Chow, W. H.; Zaridze, D.; Matveev, V.; Lubinski, J.; Trubicka, J.; Szeszenia-Dabrowska, N.; Lissowska, J.; Rudnai, P.; Fabianova, E.; Bucur, A.; Bencko, V.; Foretova, L.; Janout, V.; Boffetta, P.; Colt, J. S.; Davis, F. G.; Schwartz, K. L.; Banks, R. E.; Selby, P. J.; Harnden, P.; Berg, C. D.; Hsing, A. W.; Grubb, R. L.; Boeing, H.; Vineis, P.; Clavel-Chapelon, F.; Palli, D.; Tumino, R.; Krogh, V.; Panico, S.; Duell, E. J.; Quiros, J. R.; Sanchez, M. J.; Navarro, C.; Ardanaz, E.; Dorronsoro, M.; Khaw, K. T.; Allen, N. E.; Bueno-De-Mesquita, H. B.; Peeters, P. H. M.; Trichopoulos, D.; Linseisen, J.; Ljungberg, B.; Overvad, K.; Tjonnel, A.; Romieu, I.; Riboli, E.; Mukeria, A.; Shangina, O.; Stevens, V. L.; Thun, M. J.; Diver, W. R.; Gapstur, S. M.; Pharoah, P. D.; Easton, D. F.; Albanes, D.; Weinstein, S. J.; Virtamo, J.; Vatten, L.; Hveem, K.; Njolstad, I.; Tell, G. S.; Stoltenberg, C.; Kumar, R.; Koppova, K.; Cussenot, O.; Benhamou, S.; Oosterwijk, E.; Vermeulen, S. H.; Aben, K. K. H.; van der Marel, S. L.; Ye, Y. Q.; Wood, C. G.; Pu, X.; Mazur, A. M.; Boulygina, E. S.; Chekanov, N. N.; Foglio, M.; Lechner, D.; Gut, I.; Heath, S.; Blanche, H.; Hutchinson, A.; Thomas, G.; Wang, Z. M.; Yeager, M.; Fraumeni, J. F.; Skryabin, K. G.; McKay, J. D.; Rothman, N.; Chanock, S. J.; Lathrop, M.; Brennan, P.
  3. Nature Genetics. 2011, Jan; 43(1): 60-U83.
  1. 9.   Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
  2. Speliotes, E. K.; Willer, C. J.; Berndt, S. I.; Monda, K. L.; Thorleifsson, G.; Jackson, A. U.; Allen, H. L.; Lindgren, C. M.; Luan, J.; Magi, R.; Randall, J. C.; Vedantam, S.; Winkler, T. W.; Qi, L.; Workalemahu, T.; Heid, I. M.; Steinthorsdottir, V.; Stringham, H. M.; Weedon, M. N.; Wheeler, E.; Wood, A. R.; Ferreira, T.; Weyant, R. J.; Segre, A. V.; Estrada, K.; Liang, L. M.; Nemesh, J.; Park, J. H.; Gustafsson, S.; Kilpelanen, T. O.; Yang, J. A.; Bouatia-Naji, N.; Esko, T.; Feitosa, M. F.; Kutalik, Z.; Mangino, M.; Raychaudhuri, S.; Scherag, A.; Smith, A. V.; Welch, R.; Zhao, J. H.; Aben, K. K.; Absher, D. M.; Amin, N.; Dixon, A. L.; Fisher, E.; Glazer, N. L.; Goddard, M. E.; Heard-Costa, N. L.; Hoesel, V.; Hottenga, J. J.; Johansson, A.; Johnson, T.; Ketkar, S.; Lamina, C.; Li, S. X.; Moffatt, M. F.; Myers, R. H.; Narisu, N.; Perry, J. R. B.; Peters, M. J.; Preuss, M.; Ripatti, S.; Rivadeneira, F.; Sandholt, C.; Scott, L. J.; Timpson, N. J.; Tyrer, J. P.; van Wingerden, S.; Watanabe, R. M.; White, C. C.; Wiklund, F.; Barlassina, C.; Chasman, D. I.; Cooper, M. N.; Jansson, J. O.; Lawrence, R. W.; Pellikka, N.; Prokopenko, I.; Shi, J. X.; Thiering, E.; Alavere, H.; Alibrandi, M. T. S.; Almgren, P.; Arnold, A. M.; Aspelund, T.; Atwood, L. D.; Balkau, B.; Balmforth, A. J.; Bennett, A. J.; Ben-Shlomo, Y.; Bergman, R. N.; Bergmann, S.; Biebermann, H.; Blakemore, A. I. F.; Boes, T.; Bonnycastle, L. L.; Bornstein, S. R.; Brown, M. J.; Buchanan, T. A.; Busonero, F.; Campbell, H.; Cappuccio, F. P.; Cavalcanti-Proenca, C.; Chen, Y. D. I.; Chen, C. M.; Chines, P. S.; Clarke, R.; Coin, L.; Connell, J.; Day, I. N. M.; den Heijer, M.; Duan, J. B.; Ebrahim, S.; Elliott, P.; Elosua, R.; Eiriksdottir, G.; Erdos, M. R.; Eriksson, J. G.; Facheris, M. F.; Felix, S. B.; Fischer-Posovszky, P.; Folsom, A. R.; Friedrich, N.; Freimer, N. B.; Fu, M.; Gaget, S.; Gejman, P. V.; Geus, E. J. C.; Gieger, C.; Gjesing, A. P.; Goel, A.; Goyette, P.; Grallert, H.; Grassler, J.; Greenawalt, D. M.; Groves, C. J.; Gudnason, V.; Guiducci, C.; Hartikainen, A. L.; Hassanali, N.; Hall, A. S.; Havulinna, A. S.; Hayward, C.; Heath, A. C.; Hengstenberg, C.; Hicks, A. A.; Hinney, A.; Hofman, A.; Homuth, G.; Hui, J.; Igl, W.; Iribarren, C.; Isomaa, B.; Jacobs, K. B.; Jarick, I.; Jewell, E.; John, U; Jorgensen, T.; Jousilahti, P.; Jula, A.; Kaakinen, M.; Kajantie, E.; Kaplan, L. M.; Kathiresan, S.; Kettunen, J.; Kinnunen, L.; Knowles, J. W.; Kolcic, I.; Konig, I. R.; Koskinen, S.; Kovacs, P.; Kuusisto, J.; Kraft, P.; Kvaloy, K.; Laitinen, J.; Lantieri, O.; Lanzani, C.; Launer, L. J.; Lecoeur, C.; Lehtimaki, T.; Lettre, G.; Liu, J. J.; Lokki, M. L.; Lorentzon, M.; Luben, R. N.; Ludwig, B.; Manunta, P.; Marek, D.; Marre, M.; Martin, N. G.; McArdle, W. L.; McCarthy, A.; McKnight, B.; Meitinger, T.; Melander, O.; Meyre, D.; Midthjell, K.; Montgomery, G. W.; Morken, M. A.; Morris, A. P.; Mulic, R.; Ngwa, J. S.; Nelis, M.; Neville, M. J.; Nyholt, D. R.; O'Donnell, C. J.; O'Rahilly, S.; Ong, K. K.; Oostra, B.; Pare, G.; Parker, A. N.; Perola, M.; Pichler, I.; Pietilainen, K. H.; Platou, C. G. P.; Polasek, O.; Pouta, A.; Rafelt, S.; Raitakari, O.; Rayner, N. W.; Ridderstrale, M.; Rief, W.; Ruokonen, A.; Robertson, N. R.; Rzehak, P.; Salomaa, V.; Sanders, A. R.; Sandhu, M. S.; Sanna, S.; Saramies, J.; Savolainen, M. J.; Scherag, S.; Schipf, S.; Schreiber, S.; Schunkert, H.; Silander, K.; Sinisalo, J.; Siscovick, D. S.; Smit, J. H.; Soranzo, N.; Sovio, U.; Stephens, J.; Surakka, I.; Swift, A. J.; Tammesoo, M. L.; Tardif, J. C.; Teder-Laving, M.; Teslovich, T. M.; Thompson, J. R.; Thomson, B.; Tonjes, A.; Tuomi, T.; van Meurs, J. B. J.; van Ommen, G. J.; Vatin, V.; Viikari, J.; Visvikis-Siest, S.; Vitart, V.; Vogel, C. I. G.; Voight, B. F.; Waite, L. L.; Wallaschofski, H.; Walters, G. B.; Widen, E.; Wiegand, S.; Wild, S. H.; Willemsen, G.; Witte, D. R.; Witteman, J. C.; Xu, J. F.; Zhang, Q. Y.; Zgaga, L.; Ziegler, A.; Zitting, P.; Beilby, J. P.; Farooqi, I. S.; Hebebrand, J.; Huikuri, H. V.; James, A. L.; Kahonen, M.; Levinson, D. F.; Macciardi, F.; Nieminen, M. S.; Ohlsson, C.; Palmer, L. J.; Ridker, P. M.; Stumvoll, M.; Beckmann, J. S.; Boeing, H.; Boerwinkle, E.; Boomsma, D. I.; Caulfield, M. J.; Chanock, S. J.; Collins, F. S.; Cupples, L. A.; Smith, G. D.; Erdmann, J.; Froguel, P.; Gronberg, H.; Gyllensten, U.; Hall, P.; Hansen, T.; Harris, T. B.; Hattersley, A. T.; Hayes, R. B.; Heinrich, J.; Hu, F. B.; Hveem, K.; Illig, T.; Jarvelin, M. R.; Kaprio, J.; Karpe, F.; Khaw, K. T.; Kiemeney, L. A.; Krude, H.; Laakso, M.; Lawlor, D. A.; Metspalu, A.; Munroe, P. B.; Ouwehand, W. H.; Pedersen, O.; Penninx, B. W.; Peters, A.; Pramstaller, P. P.; Quertermous, T.; Reinehr, T.; Rissanen, A.; Rudan, I.; Samani, N. J.; Schwarz, P. E. H.; Shuldiner, A. R.; Spector, T. D.; Tuomilehto, J.; Uda, M.; Uitterlinden, A.; Valle, T. T.; Wabitsch, M.; Waeber, G.; Wareham, N. J.; Watkins, H.; Wilson, J. F.; Wright, A. F.; Zillikens, M. C.; Chatterjee, N.; McCarroll, S. A.; Purcell, S.; Schadt, E. E.; Visscher, P. M.; Assimes, T. L.; Borecki, I. B.; Deloukas, P.; Fox, C. S.; Groop, L. C.; Haritunians, T.; Hunter, D. J.; Kaplan, R. C.; Mohlke, K. L.; O'Connell, J. R.; Peltonen, L.; Schlessinger, D.; Strachan, D. P.; van Duijn, C. M.; Wichmann, H. E.; Frayling, T. M.; Thorsteinsdottir, U.; Abecasis, G. R.; Barroso, I.; Boehnke, M.; Stefansson, K.; North, K. E.; McCarthy, M. I.; Hirschhorn, J. N.; Ingelsson, E.; Loos, R. J. F.; Magic
  3. Nature Genetics. 2010, Nov 1; 42(11): 937-948.
  1. 10.   Association Between Physician Specialty and Uptake of New Medical Technologies: HPV Tests in Florida Medicaid
  2. Price, R. A.
  3. Journal of General Internal Medicine. 2010, Nov; 25(11): 1178-1185.
  1. 11.   Biological Validation of Increased Schizophrenia Risk With NRG1, ERBB4, and AKT1 Epistasis via Functional Neuroimaging in Healthy Controls
  2. Nicodemus, K. K.; Law, A. J.; Radulescu, E.; Luna, A.; Kolachana, B.; Vakkalanka, R.; Rujescu, D.; Giegling, I.; Straub, R. E.; McGee, K.; Gold, B.; Dean, M.; Muglia, P.; Callicott, J. H.; Tan, H. Y.; Weinberger, D. R.
  3. Archives of General Psychiatry. 2010, Oct; 67(10): 991-1001.
  1. 12.   Polymorphism in Alzheimer A beta Amyloid Organization Reflects Conformational Selection in a Rugged Energy Landscape
  2. Miller, Y.; Ma, B.; Nussinov, R.
  3. Chemical Reviews. 2010, Aug; 110(8): 4820-4838.
  1. 13.   Interleukin-7 Regulates Bim Proapoptotic Activity in Peripheral T-Cell Survival
  2. Li, W. Q.; Guszczynski, T.; Hixon, J. A.; Durum, S. K.
  3. Molecular and Cellular Biology. 2010, Feb; 30(3): 590-600.
  1. 14.   Euprosterna elaeasa virus genome sequence and evolution of the Tetraviridae family: Emergence of bipartite genomes and conservation of the VPg signal with the dsRNA Birnaviridae family
  2. Zeddam, J. L.; Gordon, K. H. J.; Lauber, C.; Alves, C. A. F.; Luke, B. T.; Hanzlik, T. N.; Ward, V. K.; Gorbalenya, A. E.
  3. Virology. 2010, Feb; 397(1): 145-154.
  1. 15.   Potent and broad neutralizing activity of a single chain antibody fragment against cell-free and cell-associated HIV-1
  2. Zhang, M. Y.; Borges, A. R.; Ptak, R. G.; Wang, Y. P.; Dimitrov, A. S.; Alam, S. M.; Wieczorek, L.; Bouma, P.; Fouts, T.; Jiang, S. B.; Polonis, V. R.; Haynes, B. F.; Quinnan, G. V.; Montefiori, D. C.; Dimitrov, D. S.
  3. Mabs. 2010, May-Jun; 2(3): 266-274.
  1. 16.   Metal Ions-Stimulated Iron Oxidation in Hydroxylases Facilitates Stabilization of HIF-1 alpha Protein
  2. Kaczmarek, M.; Cachau, R. E.; Topol, I. A.; Kasprzak, K. S.; Ghio, A.; Salnikow, K.
  3. Toxicological Sciences. 2009 107(2): 394-403.
  1. 17.   The RNA-binding Motif Protein 15B (RBM15B/OTT3) Acts as Cofactor of the Nuclear Export Receptor NXF1
  2. Uranishi, H.; Zolotukhin, A. S.; Lindtner, S.; Warming, S.; Zhang, G. M.; Bear, J.; Copeland, N. G.; Jenkins, N. A.; Pavlakis, G. N.; Felber, B. K.
  3. Journal of Biological Chemistry. 2009 284(38): 26106-26116.
  1. 18.   TREM-like transcript-1 protects against inflammation-associated hemorrhage by facilitating platelet aggregation in mice and humans
  2. Washington, A. V.; Gibot, S.; Acevedo, I.; Gattis, J.; Quigley, L.; Feltz, R.; De La Mota, A.; Schubert, R. L.; Gomez-Rodriguez, J.; Cheng, J.; Dutra, A.; Pak, E.; Chertov, O.; Rivera, L.; Morales, J.; Lubkowski, J.; Hunter, R.; Schwartzberg, P. L.
  3. Journal of Clinical Investigation. 2009 119(6): 1489-1501.
  1. 19.   Ly49 cluster sequence analysis in a mouse model of diabetes: an expanded repertoire of activating receptors in the NOD genome
  2. Belanger, S.; Tai, L. H.; Anderson, S. K.; Makrigiannis, A. P.
  3. Genes and Immunity. 2008 9(6): 509-521.
  1. 20.   DNA hypomethylation caused by Lsh deletion promotes erythroleukemia development
  2. Fan, T.; Schmidtmann, A.; Xi, S.; Briones, V.; Zhu, H. M.; Suh, H. C.; Gooya, J.; Keller, J. R.; Xu, H.; Roayaei, J.; Anver, M.; Ruscetti, S.; Muegge, K.
  3. Epigenetics. 2008 3(3): 134-142.
  1. 21.   Effects of leukemia inhibitory factor on lectin-binding patterns in the uterine stromal vessels of mice
  2. Wakitani, S.; Hondo, E.; Shimokawa, T.; Kusakabe, K.; Okada, T.; Nakamuta, N.; Stewart, C. L.; Kiso, Y.
  3. Immunobiology. 2008 213(2): 143-150.
  1. 22.   In vivo regulation of experimental autoimmune encephalomyelitis by NK cells: Alteration of primary adaptive responses
  2. Winkler-Pickett, R.; Young, H. A.; Cherry, J. M.; Diehl, J.; Wine, J.; Back, T.; Bere, W. E.; Mason, A. T.; Ortaldo, J. R.
  3. Journal of Immunology. 2008 180(7): 4495-4506.
  1. 23.   Preclinical pharmacology and toxicology of intravenous MV-NIS, an oncolytic measles virus administered with or without cyclophosphamide
  2. Myers, R. M.; Greiner, S. M.; Harvey, M. E.; Griesmann, G.; Jkuffel, M.; Buhrow, S. A.; Reid, J. M.; Federspiel, M.; Ames, M. M.; Dingli, D.; Schweikart, K.; Welch, A.; Dispenzieri, A.; Peng, K. W.; Russell, S. J.
  3. Clinical Pharmacology & Therapeutics. 2007, Dec; 82(6): 700-710.
  1. 24.   Genital transmission of HPV in a mouse model is potentiated by nonoxynol-9 and inhibited by carrageenan
  2. Roberts, J. N.; Buck, C. B.; Thompson, C. D.; Kines, R.; Bernardo, M.; Choyke, P. L.; Lowy, D. R.; Schiller, J. T.
  3. Nature Medicine. 2007, Jul; 13(7): 857-861.
  1. 25.   Thalidomide analogues as anticancer drugs
  2. Aragon-Ching, J. B.; Li, H. Q.; Gardner, E. R.; Figg, W. D.
  3. Recent Patents on Anti-Cancer Drug Discovery. 2007, Jun; 2(2): 167-174.
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