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  1. 1.   Effects of ascorbic acid on carcinogenicity and acute toxicity of nickel subsulfide, and on tumor transplants growth in gulonolactone oxidase knock-out mice and wild-type C57BL mice
  2. Kasprzak, K. S.; Diwan, B. A.; Kaczmarek, M. Z.; Logsdon, D. L.; Fivash, M. J.; Salnikow, K.
  3. Toxicology and Applied Pharmacology. 2011, Nov; 257(1): 32-37.
  1. 2.   Metal Ions-Stimulated Iron Oxidation in Hydroxylases Facilitates Stabilization of HIF-1 alpha Protein
  2. Kaczmarek, M.; Cachau, R. E.; Topol, I. A.; Kasprzak, K. S.; Ghio, A.; Salnikow, K.
  3. Toxicological Sciences. 2009 107(2): 394-403.
  1. 3.   Hypersusceptibility to cisplatin carcinogenicity in metallothionein-I/II double knockout mice: Production of hepatocellular carcinoma at clinically relevant doses
  2. Waalkes, M. P.; Liu, J.; Kasprzak, K. S.; Diwan, B. A.
  3. International Journal of Cancer. 2006, JUL 1; 119(1): 28-32.
  1. 4.   Effects of select PM-associated metals on alveolar macrophage phosphorylated ERK1 and-2 and iNOS expression during ongoing alteration in iron homeostasis
  2. Prophete, C.; Maciejczyk, P.; Salnikow, K.; Gould, T.; Larson, T.; Koenig, J.; Jaques, P.; Sioutas, C.; Lippmann, M.; Cohen, M.
  3. Journal of Toxicology & Environmental Health-Part A-Current Issues. 2006, MAY 15; 69(10): 935-951.
  1. 5.   A glutathione S-transferase pi-activated prodrug causes kinase activation concurrent with S-glutathionylation of proteins
  2. Townsend, D. M.; Findlay, V. J.; Fazilev, F.; Ogle, M.; Fraser, J.; Saavedra, J. E.; Ji, X. H.; Keefer, L. K.; Tew, K. D.
  3. Molecular Pharmacology. 2006, FEB; 69(2): 501-508.
  1. 6.   Ascorbate depletion: A critical step in nickel carcinogenesis?
  2. Salnikow, K.; Kasprzak, K. S.
  3. Environmental Health Perspectives. 2005, MAY; 113(5): 577-584.
  1. 7.   Mechanisms of HIF up regulation by metals
  2. Salnikow, K.; Karaczyn, A.; Inanov, S.; Zhitkovich, A.; Donald, S.; Kasprzak, K.
  3. Faseb Journal. 2005, MAR 4; 19(4, Part 1 Suppl. S): A877-A877.
  1. 8.   Anticancer metal compounds in NCI's tumor-screening database: putative mode of action
  2. Huang, R. L.; Wallqvist, A.; Covell, D. G.
  3. Biochemical Pharmacology. 2005 69(7): 1009-1039.
  1. 9.   Minimal influence of metallothionein over-expression on nickel carcinogenesis in mice
  2. Waalkes, M. P.; Liu, J.; Kasprzak, K. S.; Diwan, B. A.
  3. Toxicology Letters. 2004, NOV 28; 153(3): 357-364.
  1. 10.   Metallothionein-I/II double knockout mice are hypersensitive to lead-induced kidney carcinogenesis: Role of inclusion body formation
  2. Waalkes, M. P.; Liu, J.; Goyer, R. A.; Diwan, B. A.
  3. Cancer Research. 2004, NOV 1; 64(21): 7766-7772.
  1. 11.   Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress
  2. Salnikow, K.; Donald, S. P.; Bruick, R. K.; Zhitkovich, A.; Phang, J. M.; Kasprzak, K. S.
  3. Journal of Biological Chemistry. 2004, SEP 24; 279(39): 40337-40344.
  1. 12.   Effect of nickel and iron co-exposure on human lung cells
  2. Salnikow, K.; Li, X. M.; Lippmann, M.
  3. Toxicology and Applied Pharmacology. 2004 196(2): 258-265.
  1. 13.   HIF-1 - An oxygen and metal responsive transcription factor
  2. Maxwell, P.; Salnikow, K.
  3. Cancer Biology & Therapy. 2004 3(1): 29-35.
  1. 14.   Induction of oxidative DNA damage by carcinogenic metals
  2. Bal, W.; Kasprzak, K. S.
  3. Toxicology Letters. 2002 127(1-3): 55-62.
  1. 15.   The metallothionein-null phenotype is associated with heightened sensitivity to lead toxicity and an inability to form inclusion bodies
  2. Qu, W.; Diwan, B. A.; Liu, J.; Goyer, R. A.; Dawson, T.; Horton, J. L.; Cherian, M. G.; Waalkes, M. P.
  3. American Journal of Pathology. 2002 160(3): 1047-1056.
  1. 16.   Oxidative DNA and protein damage in metal-induced toxicity and carcinogenesis
  2. Kasprzak, K. S.
  3. Free Radical Biology and Medicine. 2002 32(10): 958-967.
  1. 17.   Possible roles of nitric oxide and redox cell signaling in metal-induced toxicity and carcinogenesis: a review
  2. Buzard, G. S.; Kasprzak, K. S.
  3. Journal of Environmental Pathology, Toxicology and Oncology. 2000 19(3): 179-99.
  1. 18.   Sequence of Exposure to Cadmium and Arsenic Determines the Extent of Toxic Effects in Male Fischer Rats
  2. Hochadel, J. F.; Waalkes, M. P.
  3. Toxicology. 1997 116(1-3): 89-98.
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