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  1. 1.   Sensitivity of mesothelioma cells to PARP inhibitors is not dependent on BAP1 but is enhanced by temozolomide in cells with high-Schlafen 11and low-MGMT expression
  2. Rathkey, Daniel; Khanal, Manakamana; Murai, Junko; Zhang, Jingli; Sengupta, Manjistha; Jiang, Qun; Morrow, Betsy; Evans,Christine; Chari,Raj; Fetsch, Patricia; Chung, Hye-Jung; Xi, Liqiang; Roth, Mark; Filie, Armando; Raffeld, Mark; Thomas, Anish; Pommier, Yves; Hassan, Raffit
  3. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2020, Jan 28; pii: S1556-0864(20)30035-6.
  1. 2.   In vitro comparison of O4-benzylfolate modulated, BCNU-induced toxicity in human bone marrow using CFU-GM and tumor cell lines
  2. Behrsing, H. P.; Furniss, M. J.; Robillard, K. A.; Tomaszewski, J. E.; Parchment, R. E.
  3. Cancer Chemotherapy and Pharmacology. 2010, May; 65(6): 1083-1091.
  1. 3.   Degradation of BRCA2 in Alkyltransferase-Mediated DNA Repair and Its Clinical Implications
  2. Philip, S.; Swaminathan, S.; Kuznetsov, S. G.; Kanugula, S.; Biswas, K.; Chang, S.; Loktionova, N. A.; Haines, D. C.; Kaldis, P.; Pegg, A. E.; Sharant, S. K.
  3. Cancer Research. 2008 68(23): 9973-9981.
  1. 4.   Polymorphisms in DNA repair genes and risk of non-Hodgkin's lymphoma in New South Wales, Australia
  2. Shen, M.; Purdue, M. R.; Kricker, A.; Lan, Q.; Grulich, A. E.; Vajdic, C. M.; Turner, J.; Whitby, D.; Chanock, S.; Rothman, N.; Armstrong, B. K.
  3. Haematologica-the Hematology Journal. 2007, Sep; 92(9): 1180-1185.
  1. 5.   Phase I trial of temozolomide plus O-6-benzylguanine for patients with recurrent or progressive malignant glioma
  2. Quinn, J. A.; Desjardins, A.; Weingart, J.; Brem, H.; Dolan, M. E.; Delaney, S. M.; Vredenburgh, J.; Rich, J.; Friedman, A. H.; Reardon, D. A.; Sampson, J. H.; Pegg, A. E.; Moschel, R. C.; Birch, R.; McLendon, R. E.; Provenzale, J. M.; Gururangan, S.; Dancey, J. E.; Maxwell, J.; Tourt-Uhlig, S.; Herndon, J. E.; Bigner, D. D.; Friedman, H. S.
  3. Journal of Clinical Oncology. 2005, OCT 1; 23(28): 7178-7187.
  1. 6.   A bifunctional DNA repair protein from Ferroplasma acidarmanus exhibits O-6-alkylguanine-DNA alkyltransferase and endonuclease V activities
  2. Kanugula, S.; Pauly, G. T.; Moschel, R. C.; Pegg, A. E.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2005, MAR 8; 102(10): 3617-3622.
  1. 7.   Intra- and intercellular variations in the repair efficiency of O-6-methylguanine, and their contribution to kinetic complexity
  2. Souliotis, V. L.; Sfikakis, P. P.; Anderson, L. M.; Kyrtopoulos, S. A.
  3. Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis. 2004, DEC 21; 568(2): 155-170.
  1. 8.   The repair of the tobacco specific nitrosamine derived adduct O-6-[4-oxo-4-(3-pyridyl)butyl]guanine by O-6-alkylguanine-DNA alkyltransferase variants
  2. Mijal, R. S.; Thomson, N. M.; Fleischer, N. L.; Pauly, G. T.; Moschel, R. C.; Kanugula, S.; Fang, Q. M.; Pegg, A. E.; Peterson, L. A.
  3. Chemical Research in Toxicology. 2004 17(3): 424-434.
  1. 9.   Repair of oligodeoxyribonucleotides by O-6-alkylguanine-DNA alkyltransferase
  2. Luu, K. X.; Kanugula, S.; Pegg, A. E.; Pauly, G. T.; Moschel, R. C.
  3. Biochemistry. 2002 41(27): 8689-8697.
  1. 10.   Phase II trial of carmustine plus O-6-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma
  2. Quinn, J. A.; Pluda, J.; Dolan, M. E.; Delaney, S.; Kaplan, R.; Rich, J. N.; Friedman, A. H.; Reardon, D. A.; Sampson, J. H.; Colvin, O. M.; Haglund, M. M.; Pegg, A. E.; Moschel, R. C.; McLendon, R. E.; Provenzale, J. M.; Gururangan, S.; Tourt-Uhlig, S.; Herndon, J. E.; Bigner, D. D.; Friedman, H. S.
  3. Journal of Clinical Oncology. 2002 20(9): 2277-2283.
  1. 11.   DNA adducts and liver DNA replication in rats during chronic exposure to N-nitrosodimethylamine (NDMA) and their relationships to the dose-dependence of NDMA hepatocarcinogenesis
  2. Souliotis, V. L.; Henneman, J. R.; Reed, C. D.; Chhabra, S. K.; Diwan, B. A.; Anderson, L. M.; Kyrtopoulos, S. A.
  3. Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis. 2002 500(1-2): 75-87.
  1. 12.   Thresholds of O-6-alkylguanine-DNA alkyltransferase which confer significant resistance of human glial tumor xenografts to treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea or temozolomide
  2. Kokkinakis, D. M.; Bocangel, D. B.; Schold, S. C.; Moschel, R. C.; Pegg, A. E.
  3. Clinical Cancer Research. 2001 7(2): 421-428.
  1. 13.   Phase I trial of carmustine plus O-6-benzylguanine for patients with recurrent or progressive malignant glioma
  2. Friedman, H. S.; Pluda, J.; Quinn, J. A.; Ewesuedo, R. B.; Long, L.; Friedman, A. H.; Cokgor, I.; Colvin, O. M.; Haglund, M. M.; Ashley, D. M.; Rich, J. N.; Sampson, J.; Pegg, A. E.; Moschel, R. C.; McLendon, R. E.; Provenzale, J. M.; Stewart, E. S.; Tourt-Uhlig, S.; Garcia-Turner, A. M.; Herndon, J. E.; Bigner, D. D.; Dolan, M. E.
  3. Journal of Clinical Oncology. 2000 18(20): 3522-3528.
  1. 14.   Potentiation of BCNU antitumor efficacy by 9-substituted O-6-benzylguanines. Effect of metabolism
  2. Kokkinakis, D. M.; Moschel, R. C.; Pegg, A. E.; Schold, S. C.
  3. Cancer Chemotherapy and Pharmacology. 2000 45(1): 69-77.
  1. 15.   Coexposure to ethanol with N-nitrosodimethylamine or 4- (methylnitrosamino)-1-(3-pyridyl)-1-butanone during lactation of rats: Marked increase in O-6-methylguanine-DNA adducts in maternal mammary gland and in suckling lung and kidney
  2. Chhabra, S. K.; Anderson, L. M.; Perella, C.; Desai, D.; Amin, S.; Kyrtopoulos, S. A.; Souliotis, V. L.
  3. Toxicology and Applied Pharmacology. 2000 169(2): 191-200.
  1. 16.   Phase I Trial of O-6-Benzylguanine For Patients Undergoing Surgery For Malignant Glioma
  2. Friedman, H. S.; Kokkinakis, D. M.; Pluda, J.; Friedman, A. H.; Cokgor, I.; Haglund, M. M.; Ashley, D. M.; Rich, J.; Dolan, M. E.; Pegg, A. E.; Moschel, R. C.; McLendon, R. E.; Kerby, T.; Herndon, J. E.; Bigner, D. D.; Schold, S. C.
  3. Journal of Clinical Oncology. 1998 16(11): 3570-3575.
  1. 17.   Comparison of Mutagenesis By O-6-Methyl- and O-6-Ethylguanine and O-4-Methylthymine in Escherichia Coli Using Double-Stranded and Gapped Plasmids
  2. Pauly, G. T.; Hughes, S. H.; Moschel, R. C.
  3. Carcinogenesis. 1998 19(3): 457-461.
  1. 18.   Reaction of O-6-Benzylguanine-Resistant Mutants of Human O-6-Alkylguanine-Dna Alkyltransferase With O-6-Benzylguanine in Oligodeoxyribonucleotides
  2. Pegg, A. E.; Kanugula, S.; Edara, S.; Pauly, G. T.; Moschel, R. C.; Goodtzova, K.
  3. Journal of Biological Chemistry. 1998 273(18): 10863-10867.
  1. 19.   Intraarterial O-6-Benzylguanine Enables the Specific Therapy of Nitrosourea-Resistant Intracranial Human Glioma Xenografts in Athymic Rats With 1,3-Bis(2-Chloroethyl)-1-Nitrosourea
  2. Kurpad, S. N.; Dolan, M. E.; McLendon, R. E.; Archer, G. E.; Moschel, R. C.; Pegg, A. E.; Bigner, D. D.; Friedman, H. S.
  3. Cancer Chemotherapy and Pharmacology. 1997 39(4): 307-316.
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