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  1. 1.   Unexpected synergistic HIV neutralization by a triple microbicide produced in rice endosperm
  2. Vamvaka, Evangelia; Farré, Gemma; Molinos-Albert, Luis M; Evans, Abbey; Canela-Xandri, Anna; Twyman, Richard M; Carrillo, Jorge; Ordóñez, Raziel A; Shattock, Robin J; O'Keefe, Barry; Clotet, Bonaventura; Blanco, Julian; Khush, Gurdev S; Christou, Paul; Capell, Teresa
  3. Proceedings of the National Academy of Sciences of the United States of America. 2018, Aug 14; 115(33): E7854-E7862.
  1. 2.   Anti-HIV microbicide development: targeting the virus is the key
  2. O'Keefe, B. R.
  3. Future Virology. 2011, May; 6(5): 553-556.
  1. 3.   Mannose-rich glycosylation patterns on HIV-1 subtype C gp120 and sensitivity to the lectins, Griffithsin, Cyanovirin-N and Scytovirin
  2. Alexandre, K. B.; Gray, E. S.; Lambson, B. E.; Moore, P. L.; Choge, I. A.; Mlisana, K.; Karim, S. S. A.; McMahon, J.; O'Keefe, B.; Chikwamba, R.; Morris, L.
  3. Virology. 2010, Jun; 402(1): 187-196.
  1. 4.   Potent and broad neutralizing activity of a single chain antibody fragment against cell-free and cell-associated HIV-1
  2. Zhang, M. Y.; Borges, A. R.; Ptak, R. G.; Wang, Y. P.; Dimitrov, A. S.; Alam, S. M.; Wieczorek, L.; Bouma, P.; Fouts, T.; Jiang, S. B.; Polonis, V. R.; Haynes, B. F.; Quinnan, G. V.; Montefiori, D. C.; Dimitrov, D. S.
  3. Mabs. 2010, May-Jun; 2(3): 266-274.
  1. 5.   Topically Applied Recombinant Chemokine Analogues Fully Protect Macaques from Vaginal Simian-Human Immunodeficiency Virus Challenge
  2. Veazey, R. S.; Ling, B. H.; Green, L. C.; Ribka, E. P.; Lifson, J. D.; Piatak, M.; Lederman, M. M.; Mosier, D.; Offord, R.; Hartley, O.
  3. Journal of Infectious Diseases. 2009 199(10): 1525-1527.
  1. 6.   Griffithsin, a potent HIV entry inhibitor, is an excellent candidate for anti-HIV microbicide
  2. Emau, P.; Tian, B.; O'Keefa, B. R.; Mori, T.; McMahon, J. B.; Palmer, K. E.; Jiang, Y.; Bekele, G.; Tsai, C. C.
  3. Journal of Medical Primatology. 2007, Aug; 36(4-5): 244-253.
  1. 7.   Critical design features of phenyl carboxylate-containing polymer microbicides
  2. Rando, R. F.; Obara, S.; Osterling, M. C.; Mankowski, M.; Miller, S. R.; Ferguson, M. L.; Krebs, F. C.; Wigdahl, B.; Labib, M.; Kokub, H.
  3. Antimicrobial Agents and Chemotherapy. 2006, Sep; 50(9): 3081-3089.
  1. 8.   Potent anti-HIV activity of scytovirin domain 1 peptide
  2. Xiong, C. Y.; O'Keefe, B. R.; Byrd, R. A.; McMahon, J. B.
  3. Peptides. 2006, Jul; 27(7): 1668-1675.
  1. 9.   Recombinant production of anti-HIV protein, griffithsin, by auto-induction in a fermentor culture
  2. Giomarelli, B.; Schumacher, K. M.; Taylor, T. E.; Sowder, R. C.; Hartley, J. L.; McMahon, J. B.; Mori, T.
  3. Protein Expression and Purification. 2006, MAY; 47(1): 194-202.
  1. 10.   Overexpression and purification of scytovirin, a potent, novel anti-HIV protein from the cultured cyanobacterium Scytonema varium
  2. Xiong, C. Y.; O'Keefe, B. R.; Botos, I.; Wlodawer, A.; McMahon, J. B.
  3. Protein Expression and Purification. 2006, Apr; 46(2): 233-239.
  1. 11.   Human alpha-defensins block papillomavirus infection
  2. Buck, C. B.; Day, P. M.; Thompson, C. D.; Lubkowski, J.; Lu, W. Y.; Lowy, D. R.; Schiller, J. T.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2006, JAN 31; 103(5): 1516-1521.
  1. 12.   Isolation and characterization of griffithsin, a novel HIV-inactivating protein, from the red alga Griffithsia sp
  2. Mori, T.; O'Keefe, B. R.; Sowder, R. C.; Bringans, S.; Gardella, R.; Berg, S.; Cochran, P.; Turpin, J. A.; Buckheit, R. W.; McMahon, J. B.; Boyd, M. R.
  3. Journal of Biological Chemistry. 2005, MAR 11; 280(10): 9345-9353.
  1. 13.   Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5
  2. Lederman, M. M.; Veazey, R. S.; Offord, R.; Mosier, D. E.; Dufour, J.; Mefford, M.; Piatak, M.; Lifson, J. D.; Salkowitz, J. R.; Rodriguez, B.; Blauvelt, A.; Hartley, O.
  3. Science. 2004, OCT 15; 306(5695): 485-487.
  1. 14.   Cyanovirin-N inhibits AIDS virus infections in vaginal transmission models
  2. Tsai, C. C.; Emau, P.; Jiang, Y. H.; Agy, M. B.; Shattock, R. J.; Schmidt, A.; Morton, W. R.; Gustafson, K. R.; Boyd, M. R.
  3. Aids Research and Human Retroviruses. 2004 20(1): 11-18.
  1. 15.   Viral resistance against a candidate HIV microbicide
  2. Ambrose, Z.; Miller, C. J.; Compton, L.; Hughes, S. H.; Lifson, J. D.; KewalRamani, V. N.
  3. Antiviral Therapy. 2003, JUN; 8(3): U38, Abstract 27-U38, Abstract 27.
  1. 16.   Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection
  2. Veazey, R. S.; Klasse, P. J.; Ketas, T. J.; Reeves, J. D.; Piatak, M.; Kunstman, K.; Kuhmann, S. E.; Marx, P. A.; Lifson, J. D.; Dufour, J.; Mefford, M.; Pandrea, I.; Wolinsky, S. M.; Doms, R. W.; DeMartino, J. A.; Siciliano, S. J.; Lyons, K.; Springer, M. S.; Moore, J. P.
  3. Journal of Experimental Medicine. 2003 198(10): 1551-1562.
  1. 17.   The microbicide cyanovirin-N expressed on the surface of commensal bacterium Streptococcus gordonii captures HIV-1
  2. Giomarelli, B.; Provvedi, R.; Meacci, F.; Maggi, T.; Medaglini, D.; Pozzi, G.; Mori, T.; McMahon, J. B.; Gardella, R.; Boyd, M. R.
  3. Aids. 2002 16(10): 1351-1356.
  1. 18.   Functional homologs of cyanovirin-N amenable to mass production in prokaryotic and eukaryotic hosts
  2. Mori, T.; Barrientos, L. G.; Han, Z. Z.; Gronenborn, A. M.; Turpin, J. A.; Boyd, M. R.
  3. Protein Expression and Purification. 2002 26(1): 42-49.
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