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  1. 1.   Bioinformatic analysis linking genomic defects to chemosensitivity and mechanism of action
  2. Covell,David
  3. PloS one. 2021, Apr 28; 16(4):
  1. 2.   Discovery and Optimization of 2H-1 lambda(2)-Pyridin-2-one Inhibitors of Mutant Isocitrate Dehydrogenase 1 for the Treatment of Cancer
  2. Rohde, Jason M.; Karavadhi, Surendra; Pragani, Rajan; Liu, Li; Fang, Yuhong; Zhang, Weihe; McIver, Andrew; Zheng, Hongchao; Liu, Qingyang; Davis, Mindy; Urban, Daniel J.; Lee, Tobie D.; Cheff, Dorian M.; Hollingshead,Melinda; Henderson, Mark J.; Martinez, Natalia J.; Brimacombe, Kyle R.; Yasgar, Adam; Zhao, Wei; Klumpp-Thomas, Carleen; Michael, Sam; Covey, Joseph; Moore,Bill; Stott, Gordon M.; Li, Zhuyin; Simeonov, Anton; Jadhav, Ajit; Frye, Stephen; Hall, Matthew D.; Shen, Min; Wang, Xiaodong; Patnaik, Samarjit; Boxer, Matthew B.
  3. Journal of Medicinal Chemistry. 2021, Apr 22; 64(8): 4913-4946.
  1. 3.   CENP-A overexpression promotes aneuploidy with karyotypic heterogeneity
  2. Shrestha, Roshan L.; Rossi, Austin; Wangsa, Darawalee; Hogan, Ann K.; Zaldana, Kimberly S.; Suva, Evelyn; Chung, Yang Jo; Sanders,Chelsea; Difilippantonio,Simone; Karpova, Tatiana S.; Karim,Baktiar; Foltz, Daniel R.; Fachinetti, Daniele; Aplan, Peter D.; Ried, Thomas; Basrai, Munira A.
  3. The Journal of Cell Biology. 2021, Feb 23; 220(4):
  1. 4.   Genomic mapping in outbred mice reveals overlap in genetic susceptibility for HZE ion- and gamma-ray-induced tumors
  2. Edmondson,Elijah; Gatti, D. M.; Ray, F. A.; Garcia, E. L.; Fallgren, C. M.; Kamstock, D. A.; Weil, M. M.
  3. SCIENCE ADVANCES. 2020, Apr; 6(16): eaax5940.
  1. 5.   Antibody-drug conjugates for cancer
  2. Chau, Cindy H.; Steeg,Pat; Figg, William D.
  3. Lancet (London, England). 2019, Aug 31; 394(10200): 793-804.
  1. 6.   IL-15/IL-15R alpha/CD80-expressing AML cell vaccines eradicate minimal residual disease in leukemic mice
  2. Shi, Yimin; Dincheva-Vogel, Lillie; Ayemoba, Charles E.; Fung, Jeffrey P.; Bergamaschi, Cristina; Pavlakis, George; Farzaneh, Farzin; Gaensler, Karin M. L.
  3. BLOOD ADVANCES. 2018, NOV 27; 2(22): 3177-3192.
  1. 7.   PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability
  2. Gryder, Berkley E.; Yohe, Marielle E.; Chou, Hsien-Chao; Zhang, Xiaohu; Marques, Joana; Wachtel, Marco; Schaefer, Beat; Sen, Nirmalya; Song, Young; Gualtieri, Alberto; Pomella, Silvia; Rota, Rossella; Cleveland, Abigail; Wen, Xinyu; Sindiri, Sivasish; Wei, Jun S.; Barr, Frederic G.; Das, Sudipto; Andresson, Thorkell; Guha, Rajarshi; Lal-Nag, Madhu; Ferrer, Marc; Shern, Jack F.; Zhao, Keji; Thomas, Craig J.; Khan, Javed
  3. Cancer Discovery. 2017, Aug; 7(8): 884-899.
  1. 8.   Stem-Cell-Based Tumorigenesis in Adult Drosophila
  2. Hou, Steven; Singh, Shree Ram; Pick, L
  3. FLY MODELS OF HUMAN DISEASES (Book Series: Current Topics in Developmental Biology). 2017; 121 : 311-337.
  1. 9.   JS-K, a Glutathione S-Transferase-Activated Nitric Oxide Donor With Antineoplastic Activity in Malignant Gliomas
  2. Weyerbrock, A.; Osterberg, N.; Psarras, N.; Baumer, B.; Kogias, E.; Werres, A.; Bette, S.; Saavedra, J. E.; Keefer, L. K.; Papazoglou, A.
  3. Neurosurgery. 2012, Feb; 70(2): 497-510.
  1. 10.   Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome
  2. Hsu, A. P.; Sampaio, E. P.; Khan, J.; Calvo, K. R.; Lemieux, J. E.; Patel, S. Y.; Frucht, D. M.; Vinh, D. C.; Auth, R. D.; Freeman, A. F.; Olivier, K. N.; Uzel, G.; Zerbe, C. S.; Spalding, C.; Pittaluga, S.; Raffeld, M.; Kuhns, D. B.; Ding, L.; Paulson, M. L.; Marciano, B. E.; Gea-Banacloche, J. C.; Orange, J. S.; Cuellar-Rodriguez, J.; Hickstein, D. D.; Holland, S. M.
  3. Blood. 2011, Sep; 118(10): 2653-2655.
  1. 11.   Hematopoiesis and leukemogenesis in mice expressing oncogenic Nras(G12D) from the endogenous locus
  2. Li, Q.; Haigis, K. M.; McDaniel, A.; Harding-Theobald, E.; Kogan, S. C.; Akagi, K.; Wong, J. C. Y.; Braun, B. S.; Wolff, L.; Jacks, T.; Shannon, K.
  3. Blood. 2011, Feb; 117(6): 2022-2032.
  1. 12.   Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation
  2. Yap, D. B.; Chu, J.; Berg, T.; Schapira, M.; Cheng, S. W. G.; Moradian, A.; Morin, R. D.; Mungall, A. J.; Meissner, B.; Boyle, M.; Marquez, V. E.; Marra, M. A.; Gascoyne, R. D.; Humphries, R. K.; Arrowsmith, C. H.; Morin, G. B.; Aparicio, S.
  3. Blood. 2011, Feb; 117(8): 2451-2459.
  1. 13.   Genetically modified dendritic cells in cancer immunotherapy: a better tomorrow?
  2. Shurin, M. R.; Gregory, M.; Morris, J. C.; Malyguine, A. M.
  3. Expert Opinion on Biological Therapy. 2010, Nov; 10(11): 1539-1553.
  1. 14.   Tumor Suppressors Sav/Scrib and Oncogene Ras Regulate Stem-Cell Transformation in Adult Drosophila Malpighian Tubules
  2. Zeng, X. K.; Singh, S. R.; Hou, D.; Hou, S. X.
  3. Journal of Cellular Physiology. 2010, Sep; 224(3): 766-774.
  1. 15.   The molecular pathology of cancer
  2. Harris, T. J. R.; McCormick, F.
  3. Nature Reviews Clinical Oncology. 2010, May; 7(5): 251-265.
  1. 16.   Identification of Vitronectin as an Extrinsic Inducer of Cancer Stem Cell Differentiation and Tumor Formation
  2. Hurt, E. M.; Chan, K.; Serrat, M. A. D.; Thomas, S. B.; Veenstra, T. D.; Farrar, W. L.
  3. Stem Cells. 2010, Mar 31; 28(3): 390-398.
  1. 17.   Autosomal dominant and sporadic monocytopenia with susceptibility to mycobacteria, fungi, papillomaviruses, and myelodysplasia
  2. Vinh, D. C.; Patel, S. Y.; Uzel, G.; Anderson, V. L.; Freeman, A. F.; Olivier, K. N.; Spalding, C.; Hughes, S.; Pittaluga, S.; Raffeld, M.; Sorbara, L. R.; Elloumi, H. Z.; Kuhns, D. B.; Turner, M. L.; Cowen, E. W.; Fink, D.; Long-Priel, D.; Hsu, A. P.; Ding, L.; Paulson, M. L.; Whitney, A. R.; Sampaio, E. P.; Frucht, D. M.; Deleo, F. R.; Holland, S. M.
  3. Blood. 2010, Feb; 115(8): 1519-1529.
  1. 18.   Laboratory correlates for a phase II trial of romidepsin in cutaneous and peripheral T-cell lymphoma
  2. Bates, S. E.; Zhan, Z. R.; Steadman, K.; Obrzut, T.; Luchenko, V.; Frye, R.; Robey, R. W.; Turner, M.; Gardner, E. R.; Figg, W. D.; Steinberg, S. M.; Ling, A.; Fojo, T.; To, K. W.; Piekarz, R. L.
  3. British Journal of Haematology. 2010, Jan; 148(2): 256-267.
  1. 19.   Recent Development of Cyclic Amide (Pyridone/Lactam) Moiety Containing Heterocycles as Protein Kinase Inhibitors
  2. Wei, L. Y.; Malhotra, S. V.
  3. Current Medicinal Chemistry. 2010, Jan; 17(3): 234-253.
  1. 20.   Epigenetic gene regulation in stem cells and correlation to cancer
  2. Mathews, L. A.; Crea, F.; Farrar, W. L.
  3. Differentiation. 2009, Jul; 78(1): 1-17.
  1. 21.   Lack of ABC transporter autoinduction in mice following long-term exposure to imatinib
  2. Gardner, E. R.; Sparreboom, A.; Verweij, J.; Figg, W. D.
  3. Cancer Biology & Therapy. 2008 7(3): 412-415.
  1. 22.   Glioblastoma stem cells produce vascular endothelial growth factor by activation of a G-protein coupled formylpeptide receptor FPR
  2. Yao, X. H.; Ping, Y. F.; Chen, J. H.; Xu, C. P.; Chen, D. L.; Zhang, R.; Wang, J. M.; Bian, X. W.
  3. Journal of Pathology. 2008 215(4): 369-376.
  1. 23.   Isolation and characterization of stem cell-like precursor cells from primary human anaplastic oligoastrocytoma
  2. Yi, L.; Zhou, Z. H.; Ping, Y. F.; Chen, J. H.; Yao, X. H.; Feng, H.; Lu, J. Y.; Wang, J. M.; Bian, X. W.
  3. Modern Pathology. 2007, Oct; 20(10): 1061-1068.
  1. 24.   Association of enzyme and transporter genotypes with the pharmacokinetics of imatinib
  2. Gardner, E. R.; Burger, H.; van Schaik, R. H.; van Oosterom, A. T.; de Bruijn, E. A.; Guetens, G.; Prenen, H.; de Jong, F. A.; Baker, S. D.; Bates, S. E.; Figg, W. D.; Verweij, J.; Sparreboom, A.; Nooter, K.
  3. Clinical Pharmacology & Therapeutics. 2006, Aug; 80(2): 192-201.
  1. 25.   Cancer stem cells - Redefining the paradigm of cancer treatment strategies
  2. Dean, M.
  3. Molecular Interventions. 2006, Jun; 6(3): 140-148.
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