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  1. 1.   TRAIL induces cytokine production via the NFkB2 pathway promoting neutrophil chemotaxis and neutrophil-mediated immune-suppression in triple negative breast cancer cells
  2. Kundu, Manjari; Greer, Yoshimi E; Lobanov, Alexei; Ridnour, Lisa; Donahue, Renee N; Ng, Yeap; Ratnayake, Shashi; White, Karley; Voeller, Donna; Weltz, Sarah; Chen, Qingrong; Lockett,Stephen; Cam, Maggie; Meerzaman, Daoud; Wink, David A; Weigert, Roberto; Lipkowitz, Stanley
  3. Cancer Letters. 2025, Jun 28; 620: 217692.
  1. 2.   Distinct allosteric networks in CDK4 and CDK6 in the cell cycle and in drug resistance
  2. Zhang,Wengang; Bradburn, Devin; Heidebrink, Gretchen; Liu, Yonglan; Jang,Hyunbum; Nussinov,Ruth; Kõivomägi, Mardo
  3. Journal of Molecular Biology. 2025, Mar 31; 169121.
  1. 3.   Discovery of potent and selective PROTACs for the protein kinase LZK for the treatment of head and neck cancer
  2. Katerji,Meghri; Bergman, Knickole L; Lindberg, Eric; Rubin,Maxine; Funk, Amy L; Woodroofe, Carolyn C; Nyswaner, Katherine; Karpinska, Kamila; Serwa, Remigiusz; Marusiak, Anna; Swenson, Rolf E; Brognard,John
  3. The Journal of Biological Chemistry. 2025, Mar 27; 108452.
  1. 4.   Inhibition of Ribosome Biogenesis in vivo Causes p53-Dependent Death and p53-Independent Dysfunction
  2. Cho, Charles J; Nguyen, Thanh; Rougeau, Amala K; Huang, Yang-Zhe; To, Sarah; Lin, Xiaobo; Thalalla Gamage,Supuni; Meier,Jordan; Mills, Jason C
  3. Cellular and Molecular Gastroenterology and Hepatology. 2025, Mar 11; 101496.
  1. 5.   Isolation and structure elucidation of Dm-CVNH, a new cyanovirin-N homolog with activity against SARS-CoV-2 and HIV-1
  2. Orfanoudaki,Maria; Krumpe,Lauren; Shenoy, Shilpa R; Wilson,Jennifer; Guszczynski, Tad; Henrich,Curtis; Temme,Joel; Gildersleeve,Jeffrey; Molina-Molina, Elisa; Erkizia, Itziar; Blanco, Julià; Izquierdo-Useros, Nuria; Montiero, Fabio; Tanuri, Amilcar; Rech, Elibio; O'Keefe,Barry
  3. The Journal of Biological Chemistry. 2025, Feb 14; 108319.
  1. 6.   Structural basis for complement receptor engagement and virus neutralization through Epstein-Barr virus gp350
  2. Joyce, M Gordon; Bu, Wei; Chen, Wei-Hung; Gillespie, Rebecca A; Andrews, Sarah F; Wheatley, Adam K; Tsybovsky,Yaroslav; Jensen, Jaime L; Stephens,Tyler; Prabhakaran, Madhu; Fisher, Brian E; Narpala, Sandeep R; Bagchi, Meghna; McDermott, Adrian B; Nabel, Gary J; Kwong, Peter D; Mascola, John R; Cohen, Jeffrey I; Kanekiyo, Masaru
  3. Immunity. 2025, Feb 11; 58(2): 295-308.e5. .
  1. 7.   Drug-Linker Constructs Bearing Unique Dual-Mechanism Tubulin Binding Payloads Tethered through Cleavable and Non-Cleavable Linkers
  2. Ford, Jacob W; VanNatta, Jennifer M; Mondal, Deboprosad; Lin, Chen-Ming; Deng, Yuling; Bai, Ruoli; Hamel,Ernest; Trawick, Mary Lynn; Pinney, Kevin G
  3. Tetrahedron. 2025, Feb 01; 171
  1. 8.   Affinity Tag-Free Purification of SARS-CoV-2 N Protein and Its Crystal Structure in Complex with ssDNA
  2. Maiti,Atanu; Matsuo,Hiroshi
  3. Biomolecules. 2024, Nov 30; 14(12):
  1. 9.   Leveraging long-acting IL-15 agonists for intratumoral delivery and enhanced antimetastatic activity
  2. Hangasky, John A; Fernández, Rocío Del Valle; Stellas,Dimitris; Hails, Guillermo; Karaliota,Sevasti; Ashley, Gary W; Felber,Barbara; Pavlakis,George; Santi, Daniel V
  3. Frontiers in Immunology. 2024, Nov 4; 15: 1458145.
  1. 10.   Non-steroidal anti-inflammatory drug use and inflammatory markers associated with gallbladder dysplasia: A case-control analysis within a series of patients undergoing cholecystectomy
  2. Rosa, Lorena; Cook, Paz; Pfeiffer, Ruth M; Kemp,Troy; Hildesheim, Allan; Pehlivanoglu, Burcin; Adsay, Volkan; Bellolio, Enrique; Araya, Juan Carlos; Pinto,Ligia; Ferreccio, Catterina; Aguayo, Gloria; Viñuela, Eduardo; Koshiol, Jill
  3. International Journal of Cancer. 2024, Oct 31;
  1. 11.   Angiopoietin-2 reverses endothelial cell dysfunction in progeria vasculature
  2. Vakili, Sahar; Izydore, Elizabeth K; Losert, Leonhard; Cabral, Wayne A; Tavarez, Urraca L; Shores, Kevin; Xue,Huijing; Erdos, Michael R; Truskey, George A; Collins, Francis S; Cao, Kan
  3. Aging Cell. 2024, Oct 18; e14375.
  1. 12.   Deoxybouvardin targets EGFR, MET, and AKT signaling to suppress non-small cell lung cancer cells
  2. Nam, A-Young; Joo, Sang Hoon; Khong,Quan; Park, Jisu; Lee, Na Yeong; Lee, Seung-On; Yoon, Goo; Park, Jin Woo; Na, MinKyun; Shim, Jung-Hyun
  3. Scientific Reports. 2024, Sep 06; 14(1): 20820.
  1. 13.   Autoinhibition of ubiquitin-specific protease 8: insights into domain interactions and mechanisms of regulation
  2. Caba, Cody; Black, Megan; Liu, Yujue; DaDalt, Ashley A; Mallare, Josh; Fan,Lixin; Harding, Rachel J; Wang, Yunxin; Vacratsis, Panayiotis O; Huang, Rui; Zhuang, Zhihao; Tong, Yufeng
  3. The Journal of Biological Chemistry. 2024, Aug 28; 107727.
  1. 14.   Human Immunodeficiency Virus Type 1 Gag Polyprotein Modulates Membrane Physical Properties like a Surfactant: Potential Implications for Virus Assembly
  2. Denieva, Zaret G; Kuzmin, Peter I; Galimzyanov, Timur R; Datta,Siddhartha; Rein,Alan; Batishchev, Oleg V
  3. ACS Infectious Diseases. 2024, Jun 25;
  1. 15.   Comprehensive proteogenomic characterization of rare kidney tumors
  2. Li, Ginny Xiaohe; Chen, Lijun; Hsiao, Yi; Mannan, Rahul; Zhang, Yuping; Luo, Jie; Petralia, Francesca; Cho, Hanbyul; Hosseini, Noshad; Leprevost, Felipe da Veiga; Calinawan, Anna; Li, Yize; Anand, Shankara; Dagar, Aniket; Geffen, Yifat; Kumar-Sinha, Chandan; Chugh, Seema; Le, Anne; Ponce, Sean; Guo, Shenghao; Zhang, Cissy; Schnaubelt, Michael; Al Deen, Nataly Naser; Chen, Feng; Caravan, Wagma; Houston, Andrew; Hopkins, Alex; Newton, Chelsea J; Wang, Xiaoming; Polasky, Daniel A; Haynes, Sarah; Yu, Fengchao; Jing, Xiaojun; Chen, Siqi; Robles, Ana I; Mesri, Mehdi; Thiagarajan,Mathangi; An, Eunkyung; Getz, Gad A; Linehan, W Marston; Hostetter, Galen; Jewell, Scott D; Chan, Daniel W; Wang, Pei; Omenn, Gilbert S; Mehra, Rohit; Ricketts, Christopher J; Ding, Li; Chinnaiyan, Arul M; Cieslik, Marcin P; Dhanasekaran, Saravana M; Zhang, Hui; Nesvizhskii, Alexey I
  3. Cell Reports. Medicine. 2024, May 21; 5(5): 101547.
  1. 16.   Slower CDK4 and faster CDK2 activation in the cell cycle
  2. Zhang,Wengang; Liu,Yonglan; Jang,Hyunbum; Nussinov,Ruth
  3. Structure (London, England : 1993). 2024, Apr 23;
  1. 17.   Systematic characterization of multi-omics landscape between gut microbial metabolites and GPCRome in Alzheimer's disease
  2. Qiu, Yunguang; Hou, Yuan; Gohel, Dhruv; Zhou, Yadi; Xu, Jielin; Bykova, Marina; Yang, Yuxin; Leverenz, James B; Pieper, Andrew A; Nussinov,Ruth; Caldwell, Jessica Z K; Brown, J Mark; Cheng, Feixiong
  3. Cell Reports. 2024, Apr 21; 43(5): 114128.
  1. 18.   Aberrant CD8+T cells drive reproductive dysfunction in female mice with elevated IFN-gamma levels
  2. Bafor, Enitome E; Erwin-Cohen, Rebecca A; Martin, Toni; Baker, Clayton; Kimmel, Adrienne E; Duverger, Olivier; Fenimore, John M; Ramba, Meredith; Spindel, Thea; Hess, Megan M; Sanford, Michael; Lazarevic, Vanja; Benayoun, Bérénice A; Young, Howard A; Valencia, Julio C
  3. Frontiers in Immunology. 2024, Apr 18; 15: 1368572.
  1. 19.   Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells
  2. Bu, Wei; Kumar, Ashish; Board, Nathan L; Kim, JungHyun; Dowdell, Kennichi; Zhang, Shu; Lei, Yona; Hostal, Anna; Krogmann, Tammy; Wang,Yanmei; Pittaluga, Stefania; Marcotrigiano, Joseph; Cohen, Jeffrey I
  3. Immunity. 2024, Mar 12; 57(3): 559-573.e6.
  1. 20.   Interferon induced circRNAs escape herpesvirus host shutoff and suppress lytic infection
  2. Dremel, Sarah E; Tagawa, Takanobu; Koparde,Vishal; Hernandez-Perez, Carmen; Arbuckle, Jesse H; Kristie, Thomas M; Krug, Laurie T; Ziegelbauer, Joseph M
  3. EMBO Reports. 2024, Mar; 25(3): 1541-1569.
  1. 21.   Staphylococcus aureus proteases trigger eosinophil-mediated skin inflammation
  2. Kline, Sabrina N; Orlando, Nicholas A; Lee, Alex J; Wu, Meng-Jen; Zhang, Jing; Youn, Christine; Feller, Laine E; Pontaza, Cristina; Dikeman, Dustin; Limjunyawong, Nathachit; Williams, Kaitlin L; Wang, Yu; Cihakova, Daniela; Jacobsen, Elizabeth A; Durum,Scott; Garza, Luis A; Dong, Xinzhong; Archer, Nathan K
  3. Proceedings of the National Academy of Sciences of the United States of America. 2024, Feb 06; 121(6): e2309243121.
  1. 22.   Unusual Vilasinin-Class Limonoids from Trichilia rubescens
  2. Amuti, Saidanxia; Saito, Yohei; Fukuyoshi, Shuichi; Miyake, Katsunori; Newman,Dave; O'Keefe,Barry; Lee, Kuo-Hsiung; Nakagawa-Goto, Kyoko
  3. Molecules (Basel, Switzerland). 2024, Jan 30; 29(3):
  1. 23.   Transcriptionally-active "defective" HIV-1 proviruses and their association with immunological non-response to antiretroviral therapy
  2. Scrimieri, Francesca; Bastian, Estella; Smith, Mindy; Rehm, Catherine A; Morse, Caryn; Kuruppu, Janaki; McLaughlin, Mary; Chang,Weizhong; Sereti, Irini; Kovacs, Joseph A; Lane, H Clifford; Imamichi, Hiromi
  3. The Journal of Infectious Diseases. 2024, Jan 16;
  1. 24.   Immune cell phenotype and function patterns across the life course in individuals from rural Uganda
  2. Nalwoga, Angela; Nakibuule, Marjorie; Roshan,Romin; Kwizera Mbonye, Moses; Miley,Wendell; Whitby,Denise; Newton, Robert; Rochford, Rosemary; Cose, Stephen
  3. Frontiers in Immunology. 2024 15: 1356635.
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