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  1. 1.   The repair of the tobacco specific nitrosamine derived adduct O-6-[4-oxo-4-(3-pyridyl)butyl]guanine by O-6-alkylguanine-DNA alkyltransferase variants
  2. Mijal, R. S.; Thomson, N. M.; Fleischer, N. L.; Pauly, G. T.; Moschel, R. C.; Kanugula, S.; Fang, Q. M.; Pegg, A. E.; Peterson, L. A.
  3. Chemical Research in Toxicology. 2004 17(3): 424-434.
  1. 2.   Repair of oligodeoxyribonucleotides by O-6-alkylguanine-DNA alkyltransferase
  2. Luu, K. X.; Kanugula, S.; Pegg, A. E.; Pauly, G. T.; Moschel, R. C.
  3. Biochemistry. 2002 41(27): 8689-8697.
  1. 3.   Phase II trial of carmustine plus O-6-benzylguanine for patients with nitrosourea-resistant recurrent or progressive malignant glioma
  2. Quinn, J. A.; Pluda, J.; Dolan, M. E.; Delaney, S.; Kaplan, R.; Rich, J. N.; Friedman, A. H.; Reardon, D. A.; Sampson, J. H.; Colvin, O. M.; Haglund, M. M.; Pegg, A. E.; Moschel, R. C.; McLendon, R. E.; Provenzale, J. M.; Gururangan, S.; Tourt-Uhlig, S.; Herndon, J. E.; Bigner, D. D.; Friedman, H. S.
  3. Journal of Clinical Oncology. 2002 20(9): 2277-2283.
  1. 4.   Debenzylation of O-6-benzyl-8-oxoguanine in human liver: implications for O-6-benzylguanine metabolism
  2. Long, L.; Moschel, R. C.; Dolan, M. E.
  3. Biochemical Pharmacology. 2001 61(6): 721-726.
  1. 5.   Phase I trial of carmustine plus O-6-benzylguanine for patients with recurrent or progressive malignant glioma
  2. Friedman, H. S.; Pluda, J.; Quinn, J. A.; Ewesuedo, R. B.; Long, L.; Friedman, A. H.; Cokgor, I.; Colvin, O. M.; Haglund, M. M.; Ashley, D. M.; Rich, J. N.; Sampson, J.; Pegg, A. E.; Moschel, R. C.; McLendon, R. E.; Provenzale, J. M.; Stewart, E. S.; Tourt-Uhlig, S.; Garcia-Turner, A. M.; Herndon, J. E.; Bigner, D. D.; Dolan, M. E.
  3. Journal of Clinical Oncology. 2000 18(20): 3522-3528.
  1. 6.   Inhibition of O-6-methylguanine-DNA methyltransferase increases azoxymethane-induced colonic tumors in rats
  2. Wali, R. K.; Skarosi, S.; Hart, J.; Zhang, Y. C.; Dolan, M. E.; Moschel, R. C.; Nguyen, L.; Mustafi, R.; Brasitus, T. A.; Bissonnette, M.
  3. Carcinogenesis. 1999 20(12): 2355-2360.
  1. 7.   Phase I Trial of O-6-Benzylguanine For Patients Undergoing Surgery For Malignant Glioma
  2. Friedman, H. S.; Kokkinakis, D. M.; Pluda, J.; Friedman, A. H.; Cokgor, I.; Haglund, M. M.; Ashley, D. M.; Rich, J.; Dolan, M. E.; Pegg, A. E.; Moschel, R. C.; McLendon, R. E.; Kerby, T.; Herndon, J. E.; Bigner, D. D.; Schold, S. C.
  3. Journal of Clinical Oncology. 1998 16(11): 3570-3575.
  1. 9.   Reaction of O-6-Benzylguanine-Resistant Mutants of Human O-6-Alkylguanine-Dna Alkyltransferase With O-6-Benzylguanine in Oligodeoxyribonucleotides
  2. Pegg, A. E.; Kanugula, S.; Edara, S.; Pauly, G. T.; Moschel, R. C.; Goodtzova, K.
  3. Journal of Biological Chemistry. 1998 273(18): 10863-10867.
  1. 10.   O-6-Alkylguanine-Dna Alkyltransferase Inactivation By Ester Prodrugs of O-6-Benzylguanine Derivatives and Their Rate of Hydrolysis By Cellular Esterases
  2. Dolan, M. E.; Roy, S. K.; Garbiras, B. J.; Helft, P.; Paras, P.; Chae, M. Y.; Moschel, R. C.; Pegg, A. E.
  3. Biochemical Pharmacology. 1998 55(10): 1701-1709.
  1. 11.   Intraarterial O-6-Benzylguanine Enables the Specific Therapy of Nitrosourea-Resistant Intracranial Human Glioma Xenografts in Athymic Rats With 1,3-Bis(2-Chloroethyl)-1-Nitrosourea
  2. Kurpad, S. N.; Dolan, M. E.; McLendon, R. E.; Archer, G. E.; Moschel, R. C.; Pegg, A. E.; Bigner, D. D.; Friedman, H. S.
  3. Cancer Chemotherapy and Pharmacology. 1997 39(4): 307-316.
  1. 12.   Effect of Dna On the Inactivation of O-6-Alkylguanine-Dna Alkyltransferase By 9-Substituted O-6-Benzylguanine Derivatives
  2. Pegg, A. E.; Chung, L.; Moschel, R. C.
  3. Biochemical Pharmacology. 1997 53(10): 1559-1564.
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