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  1. 1.   Conformational Dynamics Allows Sampling of an "Active-like" State by Oncogenic K-Ras-GDP
  2. Grudzien, Patrick; Jang,Hyunbum; Leschinsky, Nicholas; Nussinov,Ruth; Gaponenko, Vadim
  3. Journal of Molecular Biology. 2022, Jun 22; 167695.
  1. 2.   Oral Shedding of an Oncogenic Virus Alters the Oral Microbiome in HIV+ Patients
  2. Dai, Lu; Lu, Yong-Chen; Chen, Jungang; Plaisance-Bonstaff, Karlie; Mu, Shengyu; Forrest, J Craig; Whitby,Denise; Post, Steven R; Qin, Zhiqiang
  3. Frontiers in Microbiology. 2022, Apr 19; 13: 882520.
  1. 3.   Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC)
  2. Horak, Peter; Griffith, Malachi; Danos, Arpad M; Pitel, Beth A; Madhavan, Subha; Liu, Xuelu; Chow, Cynthia; Williams, Heather; Carmody, Leigh; Barrow-Laing, Lisa; Rieke, Damian; Kreutzfeldt, Simon; Stenzinger, Albrecht; Tamborero, David; Benary, Manuela; Rajagopal, Padma Sheila; Ida, Cristiane M; Lesmana, Harry; Satgunaseelan, Laveniya; Merker, Jason D; Tolstorukov, Michael Y; Campregher, Paulo Vidal; Warner, Jeremy L; Rao, Shruti; Natesan, Maya; Shen, Haolin; Venstrom, Jeffrey; Roy, Somak; Tao, Kayoko; Kanagal-Shamanna, Rashmi; Xu, Xinjie; Ritter, Deborah I; Pagel, Kym; Krysiak, Kilannin; Dubuc, Adrian; Akkari, Yassmine M; Li, Xuan Shirley; Lee, Jennifer; King, Ian; Raca, Gordana; Wagner, Alex H; Li, Marylin M; Plon, Sharon E; Kulkarni, Shashikant; Griffith, Obi L; Chakravarty, Debyani; Sonkin, Dmitriy
  3. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 2022, Jan 28;
  1. 4.   Inhibition of Nonfunctional Ras
  2. Nussinov,Ruth; Jang, Hyunbum; Gursoy, Attila; Keskin, Ozlem; Gaponenko, Vadim
  3. Cell Chemical Biology. 2021, Feb 18; 28(2): 121-133.
  1. 5.   Are Parallel Proliferation Pathways Redundant?
  2. Nussinov,Ruth; Tsai,Chung-Jung; Jang,Hyunbum
  3. Trends in biochemical sciences. 2020, Jul; 45(7): 554-563.
  1. 6.   The mechanism of PI3K activation at the atomic level
  2. Zhang,Mingzhen; Jang,Hyunbum; Nussinov,Ruth
  3. Chemical science. 2019, Mar 28; 10(12): 3671-3680.
  1. 7.   Review: Precision medicine and driver mutations: Computational methods, functional assays and conformational principles for interpreting cancer drivers
  2. Nussinov,Ruth; Jang,Hyunbum; Tsai,Chung-Jung; Cheng, Feixiong
  3. PLoS computational biology. 2019, Mar; 15(3):
  1. 8.   Calmodulin (CaM) Activates PI3K alpha by Targeting the "Soft" CaM-Binding Motifs in Both the nSH2 and cSH2 Domains of p85 alpha
  2. Zhang,Mingzhen; Li, Zhigang; Wang, Guanqiao; Jang,Hyunbum; Sacks, David B.; Zhang, Jian; Gaponenko, Vadim; Nussinov,Ruth
  3. JOURNAL OF PHYSICAL CHEMISTRY B. 2018, Dec 13; 122(49): 11137-11146.
  1. 9.   RAF Inhibitor-Induced KSR1/B-RAF Binding and Its Effects on ERK Cascade Signaling
  2. McKay, M. M. M. M. M.; Ritt, D. A.; Morrison, D. K.
  3. Current Biology. 2011, Apr; 21(7): 563-568.
  1. 10.   RNA polymerase III transcription in cancer: the BRF2 connection
  2. Cabarcas, S.; Schramm, L.
  3. Molecular Cancer. 2011, Apr; 10: 10.
  1. 11.   Genetic ablation of CCAAT/Enhancer binding protein alpha in epidermis reveals its role in suppression of epithelial tumorigenesis
  2. Loomis, K. D.; Zhu, S.; Yoon, K.; Johnson, P. F.; Smart, R. C.
  3. Cancer Research. 2007, Jul; 67(14): 6768-6776.
  1. 12.   Hyal2, where are you?
  2. Miller, A. D.; Vigdorovich, V.; Strong, R. K.; Fernandes, R. J.; Lerman, M. I.
  3. Osteoarthritis and Cartilage. 2006, Dec; 14(12): 1315-1317.
  1. 13.   K-Ras4B proteins are expressed in the nucleolus: Interaction with nucleolin
  2. Birchenall-Roberts, M. C.; Fu, T.; Kim, S. G.; Huang, Y. K.; Dambach, M.; Resau, J. H.; Ruscetti, F. W.
  3. Biochemical and Biophysical Research Communications. 2006, Sep; 348(2): 540-549.
  1. 14.   Oncogenic met receptor induces cell-cycle progression in Xenopus oocytes independent of direct Grb2 and shc binding or Mos synthesis, but requires phosphatidylinositol 3-kinase and Raf signaling
  2. Mood, K.; Saucier, C.; Ishimura, A.; Bong, Y. S.; Lee, H. S.; Park, M.; Daar, I. O.
  3. Journal of Cellular Physiology. 2006, APR; 207(1): 271-285.
  1. 15.   Conditional ablation of C/EBP beta demonstrates its keratinocyte-specific requirement for cell survival and mouse skin tumorigenesis
  2. Sterneck, E.; Zhu, S.; Ramirez, A.; Jorcano, J. L.; Smart, R. C.
  3. Oncogene. 2006, Feb; 25(8): 1272-1276.
  1. 16.   Suppression of p65 phosphorylation coincides with inhibition of I kappa B alpha polyubiquitination and degradation
  2. Hu, J.; Haseebuddin, M.; Young, M.; Colburn, N. H.
  3. Molecular Carcinogenesis. 2005, DEC; 44(4): 274-284.
  1. 17.   Cooperating cancer-gene identification through oncogenic-retrovirus-induced insertional mutagenesis
  2. Du, Y.; Spence, S. E.; Jenkins, N. A.; Copeland, N. G.
  3. Blood. 2005, OCT 1; 106(7): 2498-2505.
  1. 18.   C/EBP beta cooperates with RB : E2F to implement Ras(V12)-induced cellular senescence
  2. Sebastian, T.; Malik, R.; Thomas, S.; Sage, J.; Johnson, P. F.
  3. Embo Journal. 2005, SEP 21; 24(18): 3301-3312.
  1. 19.   Amino acid residues that are important for Hyal2 function as a receptor for jaagsiekte sheep retrovirus
  2. Duh, F. M.; Dirks, C.; Lerman, M. I.; Miller, A. D.
  3. Retrovirology. 2005, Sep; 2
  1. 20.   Effect of EBV LMP1 targeted DNAzymes on cell proliferation and apoptosis
  2. Lu, Z. X.; Ye, M.; Yan, G. R.; Li, Q.; Tang, M.; Lee, L. M.; Sun, L. Q.; Cao, Y.
  3. Cancer Gene Therapy. 2005, JUL; 12(7): 647-654.
  1. 21.   The synergistic combination of the farnesyl transferase inhibitor lonafarnib and paclitaxel enhances tubulin acetylation and requires a functional tubulin deacetylase
  2. Marcus, A. I.; Zhou, J.; O'Brate, A.; Hamel, E.; Wong, J.; Nivens, N.; El-Naggar, A.; Yao, T. P.; Khuri, F. R.; Giannakakou, P.
  3. Cancer Research. 2005, MAY 1; 65(9): 3883-3893.
  1. 22.   PKC delta plays opposite roles in growth mediated by wild-type Kit and an oncogenic Kit mutant
  2. Jelacic, T.; Linnekin, D.
  3. Blood. 2005, MAR 1; 105(5): 1923-1929.
  1. 23.   Nuclear accumulation of epidermal growth factor receptor and acceleration of G1/S stage by Epstein-Barr-encoded oncoprotein latent membrane protein 1
  2. Tao, Y. G.; Xing, S.; Deng, X. Y.; Xie, D. X.; Lee, L. M.; Liu, Y. P.; Wei, L.; Li, L. L.; Lin, D.; Qiao, W.; Gong, J. P.; Ya, C.
  3. Experimental Cell Research. 2005, FEB 15; 303(2): 240-251.
  1. 24.   Regulation of raf-1 by direct feedback phosphorylation
  2. Dougherty, M. K.; Muller, J.; Ritt, D. A.; Zhou, M.; Zhou, X. Z.; Copeland, T. D.; Conrads, T. P.; Veenstra, T. D.; Lu, K. P.; Morrison, D. K.
  3. Molecular Cell. 2005, JAN 21; 17(2): 215-224.
  1. 25.   5-Lipoxygenase regulates senescence-like growth arrest by promoting ROS-dependent p53 activation
  2. Catalano, A.; Rodilossi, S.; Caprari, P.; Coppola, V.; Procopio, A.
  3. Embo Journal. 2005, JAN 12; 24(1): 170-179.
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