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  1. 1.   Histidine Tag-Specific PEGylation Improves the Circulating Half-Life of TIMP2
  2. Toor, Jack; Grabowska, Wiktoria R; Johnson, Adam L; Jones,Jane; Stetler-Stevenson, William G; Khalili, Hanieh; Peeney, David
  3. ACS Applied Bio Materials. 2025, Feb 21;
  1. 2.   Unraveling the dynamics of B7-H3-targeting therapeutic antibodies in cancer through PET imaging and antibody pharmacokinetics
  2. Fernandes, Bruna; Olkowski, Colleen P; Ghaemi, Behnaz; Basuli, Falguni; Shi, Jianfeng; Kiesewetter, Dale O; Lang, Lixin; Elijah, Edmondson; Swenson, Rolf; Choyke, Peter L; Lin, Frank I; Jacobson, Orit
  3. Journal of Controlled Release : official journal of the Controlled Release Society. 2025, Jan 13;
  1. 3.   Nano-mupirocin as tumor-targeted antibiotic: Physicochemical, immunotoxicological and pharmacokinetic characterization, and effect on gut microbiome
  2. Cern, Ahuva; Skoczen,Sarah; Snapp, Kelsie S; Hod, Atara; Zilbersheid, Daniel; Bavli, Yaelle; Alon-Maimon, Tamar; Bachrach, Gilad; Wei, Xiaohui; Berman, Bella; Yassour, Moran; Cedrone,Edward; Neun,Barry; Dobrovolskaia,Marina; Clogston,Jeffrey; Stern,Steve; Barenholz, Yechezkel
  3. Journal of Controlled Release : official journal of the Controlled Release Society. 2024, Aug 2; 373: 713-726.
  1. 4.   Distinct uptake and elimination profiles for trastuzumab, human IgG and biocytin-TMR in experimental HER2+ brain metastases of breast cancer
  2. Silvestri, Vanesa L; Tran, Andy D; Chung, Monika; Chung, Natalie; Gril, Brunilde; Robinson,Christina; Difilippantonio,Simone; Wei, Debbie; Kruhlak, Michael J; Peer, Cody J; Figg, W Douglas; Khan, Imran; Steeg, Patricia S
  3. Neuro-Oncology. 2024, Feb 13;
  1. 5.   Viral dissemination and immune activation modulate antiretroviral drug levels in lymph nodes of SIV-infected rhesus macaques
  2. Srinivasula,Sharat; Degrange, Paula; Perazzolo, Simone; Bonvillain, Andrew; Tobery, Amanda; Kaplan, Jacob; Jang, Hyukjin; Turnier, Refika; Davies, Michael; Cottrell, Mackenzie; Ho, Rodney J Y; Di Mascio, Michele
  3. Frontiers in Immunology. 2023, Sep 18; 14: 1213455.
  1. 6.   A phase 1 and pharmacodynamic study of chronically-dosed, single-agent veliparib (ABT-888) in patients with BRCA1- or BRCA2-mutated cancer or platinum-refractory ovarian or triple-negative breast cancer
  2. Manzo, Julia; Puhalla, Shannon; Pahuja, Shalu; Ding, Fei; Lin, Yan; Appleman, Leonard; Tawbi, Hussein; Stoller, Ronald; Lee, James J; Diergaarde, Brenda; Kiesel, Brian F; Yu, Jing; Tan, Antoinette R; Belani, Chandra P; Chew, Helen; Garcia, Agustin A; Morgan, Robert J; Wahner Hendrickson, Andrea E; Visscher, Daniel W; Hurley, Rachel M; Kaufmann, Scott H; Swisher, Elizabeth M; Oesterreich, Steffi; Katz, Tiffany; Ji,Jay; Zhang, Yiping; Parchment, Ralph E; Chen, Alice; Duan, Wenrui; Giranda, Vincent; Shepherd, Stacie P; Ivy, S Percy; Chu, Edward; Beumer, Jan H
  3. Cancer Chemotherapy and Pharmacology. 2022, Apr 18; 89(5): 721-735.
  1. 7.   Bioequivalence assessment of high-capacity polymeric micelle nanoformulation of paclitaxel and Abraxane (R) in rodent and non-human primate models using a stable isotope tracer assay
  2. Hwang, Duhyeong; Vinod, Natasha; Skoczen,Sarah; Ramsey, Jacob D.; Snapp,Kelsie; Montgomery, Stephanie A.; Wang, Mengzhe; Lim, Chaemin; Frank, Jonathan E.; Sokolsky-Papkov, Marina; Li, Zibo; Yuan, Hong; Kabanov, Alexander; Stern,Steve
  3. Biomaterials . 2021, Nov; 278
  1. 8.   Adjuvant Sirolimus Does Not Improve Outcome in Pet Dogs Receiving Standard-of-Care Therapy for Appendicular Osteosarcoma: A Prospective, Randomized Trial of 324 Dogs
  2. LeBlanc, Amy K.; Mazcko, Christina N.; Cherukuri, Aswini; Berger,Erika; Kisseberth, William C.; Brown, Megan E.; Lana, Susan E.; Weishaar, Kristen; Flesner, Brian K.; Bryan, Jeffrey N.; Vail, David M.; Burton, Jenna H.; Willcox, Jennifer L.; Mutsaers, Anthony J.; Woods, J. Paul; Northrup, Nicole C.; Saba, Corey; Curran, Kaitlin M.; Leeper, Haley; Wilson-Robles, Heather; Wustefeld-Janssens, Brandan G.; Lindley, Stephanie; Smith, Annette N.; Dervisis, Nikolaos; Klahn, Shawna; Higginbotham, Mary Lynn; Wouda, Raelene M.; Krick, Erika; Mahoney, Jennifer A.; London, Cheryl A.; Barber, Lisa G.; Balkman, Cheryl E.; McCleary-Wheeler, Angela L.; Suter, Steven E.; Martin, Olya; Borgatti, Antonella; Burgess, Kristine; Childress, Michael O.; Fidel, Janean L.; Allstadt, Sara D.; Gustafson, Daniel L.; Selmic, Laura E.; Khanna, Chand; Fan, Timothy M.
  3. CLINICAL CANCER RESEARCH. 2021, Jun 1; 27: 3005-3016.
  1. 9.   Phase 1 study of Z-endoxifen in patients with advanced gynecologic, desmoid, and hormone receptor-positive solid tumors
  2. Takebe, Naoko; Coyne, Geraldine O'Sullivan; Kummar, Shivaani; Collins, Jerry; Reid, Joel M; Piekarz, Richard; Moore, Nancy; Juwara, Lamin; Johnson,Barry; Bishop, Rachel; Lin, Frank I; Mena, Esther; Choyke, Peter L; Lindenberg, M Liza; Rubinstein, Larry V; Bonilla, Cecilia Monge; Goetz, Matthew P; Ames, Matthew M; McGovern, Renee M; Streicher, Howard; Covey, Joseph M; Doroshow, James H; Chen, Alice P
  3. Oncotarget. 2021, Feb 16; 12(4): 268-277.
  1. 10.   Predicting Volume of Distribution in Humans: Performance of in silico Methods for A Large Set of Structurally Diverse Clinical Compounds
  2. Murad, Neha; Pasikanti, Kishore K; Madej,Benjamin; Minnich, Amanda; McComas, Juliet M; Crouch, Sabrinia; Polli, Joseph W; Weber, Andrew D
  3. Drug metabolism and disposition: the biological fate of chemicals. 2021, Feb 1; 49: 169-178.
  1. 11.   Safety and Stability of Antibody-Dye Conjugate in Optical Molecular Imaging
  2. Pei, Jacqueline; Juniper, Georgina; van den Berg, Nynke S.; Nisho, Naoki; Broadt,Trevor; Welch,Anthony; Yi, Grace S.; Raymundo, Roan C.; Chirita, Stefania U.; Lu, Guolan; Krishnan, Giri; Lee, Yu-Jin; Kapoor, Shrey; Zhou, Quan; Colevas, A. Dimitrios; Lui, Natalie S.; Poultsides, George A.; Li, Gordon; Zinn, Kurt R.; Rosenthal, Eben L.
  3. MOLECULAR IMAGING AND BIOLOGY. 2020, SEP 3;
  1. 12.   LC-MS/MS assay coupled with carboxylic acid magnetic bead affinity capture to quantitatively measure cationic host defense peptides (HDPs) in complex matrices with application to preclinical pharmacokinetic studies
  2. O'Neill,Maura; Chan,King; Jaynes, Jesse M; Knotts, Zachary; Xu,Xia; Abisoye-Ogunniyan, Abisola; Guerin,Theresa; Schlomer,Jerome; Li, Dandan; Cary, Jeffrey W; Rajasekaran, Kanniah; Yates, Clayton; Kozlov,Serguei; Andresson,Thorkell; Rudloff, Udo
  3. Journal of pharmaceutical and biomedical analysis. 2020, Mar 20; 181: 113093.
  1. 13.   Heterogeneous antiretroviral drug distribution and HIV/SHIV detection in the gut of three species
  2. Thompson, Corbin G; Rosen, Elias P; Prince, Heather M A; White, Nicole; Sykes, Craig; de la Cruz, Gabriela; Mathews, Michelle; Deleage,Claire; Estes,Jake; Charlins, Paige; Mulder, Leila R; Kovarova, Martina; Adamson, Lourdes; Arora, Shifali; Dellon, Evan S; Peery, Anne F; Shaheen, Nicholas J; Gay, Cynthia; Muddiman, David C; Akkina, Ramesh; Victor Garcia, J; Luciw, Paul; Kashuba, Angela D M
  3. Science translational medicine. 2019, Jul 03; 11(499): pii: eaap8758..
  1. 14.   Population Pharmacokinetics and Pharmacodynamics of Disulfiram on Inducing Latent HIV-1 Transcription in a Phase 2b Trial
  2. Lee, Sulggi A; Elliott, Julian H; McMahon, James; Hartogenesis, Wendy; Bumpus, Namandje N; Lifson, Jeffrey; Gorelick, Robert; Bacchetti, Peter; Deeks, Steven G; Lewin, Sharon R; Savic, Radojka M
  3. Clinical pharmacology and therapeutics. 2019, Mar; 105(3): 692-702.
  1. 15.   Disruption of the Rbm38-eIF4E Complex with a Synthetic Peptide Pep8 Increases p53 Expression
  2. Lucchesi, Christopher A.; Zhang, Jin; Ma, Buyong; Chen, Mingyi; Chen, Xinbin
  3. CANCER RESEARCH. 2019, FEB 15; 79(4): 807-818.
  1. 16.   Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-Kras(G12D/+);Tp53(R172H/+) (KPC) mice, a genetically engineered model of pancreatic cancer
  2. Vilimas, Tomas; Wang, Amy Q.; Patnaik, Samarjit; Hughes, Emma A.; Singleton, Marc D.; Knotts, Zachary; Li, Dandan; Frankowski, Kevin; Schlomer, Jerome; Guerin, Theresa; Springer, Stephanie; Drennan, Catherine; Dextras, Christopher; Wang, Chen; Gilbert, Debra; Southall, Noel; Ferrer, Marc; Huang, Sui; Kozlov, Serguei; Marugan, Juan; Xu, Xin; Rudloff, Udo
  3. CANCER CHEMOTHERAPY AND PHARMACOLOGY. 2018, Dec; 82(6): 1067-1080.
  1. 17.   Optimized administration of hetIL-15 expands lymphocytes and minimizes toxicity in rhesus macaques
  2. Bergamaschi, Cristina; Watson, Dennis; Valentin, Antonio; Bear, Jenifer; Peer, Cody J; Figg, William D; Felber, Barbara; Pavlakis, George
  3. Cytokine. 2018, Aug; 108: 213-224.
  1. 18.   First-in-human study of the epichaperome inhibitor PU-H71: clinical results and metabolic profile
  2. Speranza, Giovanna; Anderson, Larry; Chen, Alice P; Do, Khanh; Eugeni, Michelle; Weil, Marcie; Rubinstein, Larry; Majerova, Eva; Collins, Jerry; Horneffer, Yvonne; Juwara, Lamin; Zlott, Jennifer; Bishop, Rachel; Conley, Barbara A; Streicher, Howard; Tomaszewski, Joseph; Doroshow, James H; Kummar, Shivaani
  3. Investigational New Drugs. 2018, Apr; 36(2): 230-239.
  1. 19.   Pharmacokinetics of dacarbazine (DTIC) in pregnancy
  2. Kantrowitz-Gordon, Ira; Hays, Karen; Kayode, Olumide; Kumar, Aditya R.; Kaplan, Henry G.; Reid, Joel M.; Safgren, Stephanie L.; Ames, Matthew M.; Easterling, Thomas R.; Hebert, Mary F.
  3. Cancer Chemotherapy and Pharmacology. 2018, Mar; 81(3): 455-460.
  1. 20.   Differential Influence of the Antiretroviral Pharmacokinetic Enhancers Ritonavir and Cobicistat on Intestinal P-Glycoprotein Transport and the Pharmacokinetic/Pharmacodynamic Disposition of Dabigatran
  2. Kumar, Parag; Gordon, Lori A.; Brooks, Kristina M.; George, Jomy M.; Kellogg, Anela; McManus, Maryellen; Alfaro, Raul M.; Nghiem, Khanh; Lozier, Jay; Hadigan, Colleen; Penzak, Scott R.
  3. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2017, NOV; 61(11):
  1. 21.   Decreased Absorption of Dolutegravir and Tenofovir Disoproxil Fumarate, But Not Emtricitabine, in an HIV-Infected Patient Following Oral and Jejunostomy-Tube Administration
  2. Brooks, Kristina M.; Garrett, Katy L.; Kuriakose, Safia; George, Jomy M.; Balba, Gayle; Bailey, Bria; Anderson, Megan; Lane, H. Clifford; Maldarelli, Frank; Pau, Alice K.
  3. Pharmacotherapy. 2017, Aug; 37(8): E82-E89.
  1. 22.   Parent-Metabolite Pharmacokinetic Modeling and Pharmacodynamics of Veliparib (ABT-888), a PARP Inhibitor, in Patients With BRCA 1/2-Mutated Cancer or PARP-Sensitive Tumor Types
  2. Niu, Jing; Scheuerell, Christie; Mehrotra, Shailly; Karan, Sharon; Puhalla, Shannon; Kiesel, Brian F; Ji, Jay; Chu, Edward; Gopalakrishnan, Mathangi; Ivaturi, Vijay; Gobburu, Jogarao; Beumer, Jan H
  3. Journal of clinical pharmacology. 2017, Aug; 57(8): 977-987.
  1. 23.   Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response
  2. Backman, Joshua D.; O'Connell, Jeffrey R.; Tanner, Keith; Peer, Cody J.; Figg, William D.; Spencer, Shawn D.; Mitchell, Braxton D.; Shuldiner, Alan R.; Yerges-Armstrong, Laura M.; Horenstein, Richard B.; Lewis, Joshua P.
  3. PHARMACOGENETICS AND GENOMICS. 2017, Apr; 27(4): 159-163.
  1. 24.   Antiretroviral Boosting Agent Cobicistat Increases the Pharmacokinetic Exposure and Anticoagulant Effect of Dabigatran in HIV-Negative Healthy Volunteers.
  2. Gordon, Lori A; Kumar, Parag; Brooks, Kristina M; Kellogg, Anela; McManus, Maryellen; Alfaro, Raul M; Nghiem, Khanh; George, Jomy M; Lozier, Jay; Penzak, Scott R; Hadigan, Colleen
  3. Circulation. 2016, Dec 6; 134(23): 1909-1911.
  1. 25.   Prediction of pharmacokinetic and toxicological parameters of a 4-phenylcoumarin isolated from geopropolis: in silico and in vitro approaches
  2. da Cunha, M. G.; Franco, G. C.; Franchin, M.; Beutler, John; de Alencar, S. M.; Ikegaki, M.; Rosalen, P. L.
  3. Toxicology Letters. 2016, Nov 30; 263: 6-10.
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