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  1. 1.   Calorimetric investigation of phosphorylated and non-phosphorylated peptide ligand binding to the human Grb7-SH2 domain
  2. Spuches, A. M.; Argiros, H. J.; Lee, K. H.; Haas, L. L.; Perch, S. C.; Krag, D. N.; Roller, P. P.; Wilcox, D. E.; Lyons, B. A.
  3. Journal of Molecular Recognition. 2007, Jul-Aug; 20(4): 245-252.
  1. 2.   Development of Grb2 SH2 domain signaling antagonists: A potential new class of antiproliferative agents
  2. Burke, T. R.
  3. International Journal of Peptide Research and Therapeutics. 2006, Mar; 12(1): 33-48.
  1. 3.   Examination of phosphoryl-mimicking functionalities within a macrocyclic Grb2 SH2 domain-binding platform
  2. Kang, S. U.; Shi, Z. D.; Worthy, K. M.; Bindu, L. K.; Dharmawardana, P. G.; Choyke, S. J.; Bottaro, D. P.; Fisher, R. J.; Burke, T. R.
  3. Journal of Medicinal Chemistry. 2005, JUN 16; 48(12): 3945-3948.
  1. 4.   Ring-closing metathesis of C-terminal allylglycine residues with an N-terminal beta-vinyl-substituted phosphotyrosyl mimetic as an approach to novel Grb2 SH2 domain-binding macrocycles
  2. Oishi, S.; Shi, Z. D.; Worthy, K. M.; Bindu, L. K.; Fisher, R. J.; Burke, T. R.
  3. Chembiochem. 2005, APR; 6(4): 668-674.
  1. 5.   Design and synthesis of conformationally constrained Grb2 SH2 domain binding peptides employing alpha-methylphenylalanyl based phosphotyrosyl mimetics
  2. Oishi, S.; Karki, R. G.; Kang, S. U.; Wang, X. Z.; Worthy, K. M.; Bindu, L. K.; Nicklaus, M. C.; Fisher, R. J.; Burke, T. R.
  3. Journal of Medicinal Chemistry. 2005, FEB 10; 48(3): 764-772.
  1. 6.   Evaluation of macrocyclic Grb2 SH2 domain-binding peptide mimetics prepared by ring-closing metathesis of C-terminal allylglycines with an N-terminal beta-vinyl-substituted phosphotyrosyl mimetic
  2. Oishi, S.; Karki, R. G.; Shi, Z. D.; Worthy, K. M.; Bindu, L.; Chertov, O.; Esposito, D.; Frank, P.; Gillette, W. K.; Maderia, M.; Hartley, J.; Nicklaus, M. C.; Barchi, J. J.; Fisher, R. J.; Burke, T. R.
  3. Bioorganic & Medicinal Chemistry. 2005 13(7): 2431-2438.
  1. 8.   Synthesis of the first alpha-fluoro-phosphotyrosyl mimetic
  2. Shi, Z. D.; Liu, H. P.; Zhang, M. C.; Yang, D. J.; Burke, T. R.
  3. Synthetic Communications. 2004 34(21): 3883-3889.
  1. 9.   Synthesis of alpha,alpha-disubstituted 4-phosphonophenylalanine analogues as conformationally-constrained phosphotyrosyl mimetics
  2. Oishi, S.; Kang, S. U.; Liu, H. P.; Zhang, M. C.; Yang, D. J.; Deschamps, J. R.; Burke, T. R.
  3. Tetrahedron. 2004 60(13): 2971-2977.
  1. 10.   Enantioselective synthesis of (S)-3-carboxy-4-((carboxy)difluoromethyl)phenylalanine in protected form and its incorporation into a PTP-1B-directed tripeptide
  2. Kang, S. U.; Yang, G.; Li, W.; Zhang, Z. Y.; Burke, T. R.
  3. Chemistry & Biodiversity. 2004 1(4): 626-633.
  1. 11.   Synthesis of a phosphotyrosyl analogue having X-1, X-2 and phi angles constrained to values observed for an SH2 domain-bound phosphotyrosyl residue
  2. Wang, X. Z.; Yao, Z. J.; Liu, H. P.; Zhang, M. C.; Yang, D. J.; George, C.; Burke, T. R.
  3. Tetrahedron. 2003 59(32): 6087-6093.
  1. 12.   Phosphoryltyrosyl mimetics in the design of peptide-based signal transduction inhibitors
  2. Burke, T. R.; Yao, Z. J.; Liu, D. G.; Voigt, J.; Gao, Y.
  3. Biopolymers. 2001 60(1): 32-44.
  1. 13.   Utilization of a peptide lead for the discovery of a novel PTP1M-binding motif
  2. Gao, Y.; Voigt, J.; Zhao, H.; Pais, G. C. G.; Zhang, X. C.; Wu, L.; Zhang, Z. Y.; Burke, T. R.
  3. Journal of Medicinal Chemistry. 2001 44(18): 2869-2878.
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