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  1. 1.   Optimization of the PROTAC linker region of the proteasome substrate receptor hRpn13 rationalized structural modeling with molecular dynamics
  2. Lu,Xiuxiu; Sabbasani, Venkata R; Walters,Kylie; Swenson, Rolf E; Walters,Kylie
  3. The Journal of Biological Chemistry. 2025, Apr 18; 108520.
  1. 2.   Discovery of potent and selective PROTACs for the protein kinase LZK for the treatment of head and neck cancer
  2. Katerji,Meghri; Bergman, Knickole L; Lindberg, Eric; Rubin,Maxine; Funk, Amy L; Woodroofe, Carolyn C; Nyswaner, Katherine; Karpinska, Kamila; Serwa, Remigiusz; Marusiak, Anna; Swenson, Rolf E; Brognard,John
  3. The Journal of Biological Chemistry. 2025, Mar 27; 108452.
  1. 3.   Methotrexate-based PROTACs as DHFR-specific chemical probes
  2. Rana, Sandeep; Dranchak, Patricia; Dahlin, Jayme L; Lamy, Laurence; Li,Wenqing; Oliphant, Erin; Shrimp, Jonathan H; Rajacharya, Girish H; Tharakan, Ravi; Holland, David O; Whitten, Apryl S; Wilson, Kelli M; Singh, Pankaj K; Durum,Scott; Tao, Dingyin; Rai, Ganesha; Inglese, James
  3. Cell Chemical Biology. 2023, Oct 17;
  1. 4.   Targeted protein degradation: from small molecules to complex organelles-a Keystone Symposia report
  2. Cable, Jennifer; Weber-Ban, Eilika; Clausen, Tim; Walters,Kylie; Sharon, Michal; Finley, Daniel J.; Gu, Yangnan; Hanna, John; Feng, Yue; Martens, Sascha; Simonsen, Anne; Hansen, Malene; Zhang, Hong; Goodwin, Jonathan M.; Reggio, Alessio; Chang, Chunmei; Ge, Liang; Schulman, Brenda A.; Deshaies, Raymond J.; Dikic, Ivan; Harper, J. Wade; Wertz, Ingrid E.; Thoma, Nicolas H.; Slabicki, Mikolaj; Frydman, Judith; Jakob, Ursula; David, Della C.; Bennett, Eric J.; Bertozzi, Carolyn R.; Sardana, Richa; Eapen, Vinay V.; Carra, Serena
  3. Annals of the New York Academy of Sciences. 2022, Jan;
  1. 5.   Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome
  2. Chen,Xiang; Dorris, Zachary; Shi,Dan; Huang, Rick K; Khant,Htet; Fox,Tara; De Val Alda,Natalia; Williams, Dewight; Zhang,Ping; Walters,Kylie
  3. Structure (London, England : 1993). 2020, NOV 3; 28(11): 1206-+.
  1. 6.   Vav1 is Essential for HIF-1a Activation via a Lysosomal VEGFR1-Mediated Degradation Mechanism in Endothelial Cells
  2. Hong,Jaewoo; Min,Yongfen; Wuest, Todd; Lin,Charles
  3. Cancers. 2020, JUN; 12(6): E1374.
  1. 7.   Crystal structure of the Schizosaccharomyces pombe U7BR E2-binding region in complex with Ubc7
  2. Hann, Zachary S; Metzger,Meredith; Weissman,Allan; Lima, Christopher D
  3. Acta crystallographica. Section F, Structural biology communications. 2019, Aug 01; 75(Pt 8): 552-560.
  1. 8.   A set of aspartyl protease-deficient strains for improved expression of heterologous proteins in Kluyveromyces lactis
  2. Ganatra, M. B.; Vainauskas, S.; Hong, J. M.; Taylor, T. E.; Denson, J. P. M.; Esposito, D.; Read, J. D.; Schmeisser, H.; Zoon, K. C.; Hartley, J. L.; Taron, C. H.
  3. Fems Yeast Research. 2011, Mar; 11(2): 168-178.
  1. 9.   Sequence signatures and mRNA concentration can explain two-thirds of protein abundance variation in a human cell line
  2. Vogel, C.; Abreu, R. D.; Ko, D. J.; Le, S. Y.; Shapiro, B. A.; Burns, S. C.; Sandhu, D.; Boutz, D. R.; Marcotte, E. M.; Penalva, L. O.
  3. Molecular Systems Biology. 2010, Aug; 6: 9.
  1. 10.   Increased oxidation and degradation of cytosolic proteins in alcohol-exposed mouse liver and hepatoma cells
  2. Kim, B. J.; Hood, B. L.; Aragon, R. A.; Hardwick, J. R.; Conrads, T. R.; Veenstra, T. D.; Song, B. J.
  3. Proteomics. 2006, FEB; 6(4): 1250-1260.
  1. 11.   The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain,, RING finger, and an E2-binding site
  2. Chen, B.; Mariano, J.; Tsai, Y. C.; Chan, A. H.; Cohen, M.; Weissman, A. M.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2006, JAN 10; 103(2): 341-346.
  1. 12.   A novel RING-type ubiquitin ligase breast cancer-associated gene 2 correlates with outcome in invasive breast cancer
  2. Burger, A. M.; Gao, Y. G.; Amemiya, Y.; Kahn, H. J.; Kitching, R.; Yang, Y. L.; Sun, P.; Narod, S. A.; Hanna, W. M.; Seth, A. K.
  3. Cancer Research. 2005, NOV 15; 65(22): 10401-10412.
  1. 13.   Expression, purification, and properties of the Ubc4/5 family of E2 enzymes
  2. Lorick, K. L.; Jensen, J. P.; Weissman, A. M.
  3. Methods in Enzymology. 2005; 398 : 54-68.
  1. 14.   Expression and evaluation of RING finger proteins
  2. Yang, Y. L.; Lorick, K. L.; Jensen, J. P.; Weissman, A. M.
  3. Methods in Enzymology. 2005; 398 : 103-112.
  1. 15.   Mdm2 binds p73 alpha without targeting degradation
  2. Balint, E.; Bates, S.; Vousden, K. H.
  3. Oncogene. 1999 18(27): 3923-3929.
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