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  1. 1.   Oxime-based linker libraries as a general approach for the rapid generation and screening of multidentate inhibitors
  2. Bahta, M.; Liu, F.; Kim, S. E.; Stephen, A. G.; Fisher, R. J.; Burke, T. R.
  3. Nature Protocols. 2012, Apr; 7(4): 686-702.
  1. 2.   Association of Src-Related Kinase Lyn with the Interleukin-2 Receptor and Its Role in Maintaining Constitutive Phosphorylation of JAK/STAT in Human T-Cell Leukemia Virus Type 1-Transformed T Cells
  2. Shuh, M. S. M.; Morse, B. A.; Heidecker, G.; Derse, D.
  3. Journal of Virology. 2011, May; 85(9): 4623-4627.
  1. 3.   Structure of human dual-specificity phosphatase 27 at 2.38 angstrom resolution
  2. Lountos, G. T.; Tropea, J. E.; Waugh, D. S.
  3. Acta Crystallographica Section D-Biological Crystallography. 2011, May; 67: 471-479.
  1. 4.   Two-tiered Approach Identifies a Network of Cancer and Liver Disease-related Genes Regulated by miR-122
  2. Boutz, D. R.; Collins, P. J.; Suresh, U.; Lu, M. Z.; Ramirez, C. M.; Fernandez-Hernando, C.; Huang, Y. F.; Abreu, R. D.; Le, S. Y.; Shapiro, B. A.; Liu, A. M.; Luk, J. M.; Aldred, S. F.; Trinklein, N. D.; Marcotte, E. M.; Penalva, L. O. F.
  3. Journal of Biological Chemistry. 2011, May; 286(20): 18066-18078.
  1. 5.   Optimization of a Cyclic Peptide Inhibitor of Ser/Thr Phosphatase PPM1D (Wip1)
  2. Hayashi, R.; Tanoue, K.; Durell, S. R.; Chatterjee, D. K.; Jenkins, L. M. M.; Appella, D. H.; Appella, E.
  3. Biochemistry. 2011, May; 50(21): 4537-4549.
  1. 6.   TLR-mediated signaling pathways circumvent the requirement for DAP12 in mast cells for the induction of inflammatory mediator release
  2. Smrz, D.; Iwaki, S.; McVicar, D. W.; Metcalfe, D. D.; Gilfillan, A. M.
  3. European Journal of Immunology. 2010, Dec; 40(12): 3557-3569.
  1. 7.   A rapid oxime linker-based library approach to identification of bivalent inhibitors of the Yersinia pestis protein-tyrosine phosphatase, YopH
  2. Liu, F.; Hakami, R. M.; Dyas, B.; Bahta, M.; Lountos, G. T.; Waugh, D. S.; Ulrich, R. G.; Burke, T. R.
  3. Bioorganic & Medicinal Chemistry Letters. 2010, May; 20(9): 2813-2816.
  1. 8.   Analysis of the linker for activation of T cells and the linker for activation of B cells in natural killer cells reveals a novel signaling cassette, dual usage in ITAM signaling, and influence on development of the Ly49 repertoire
  2. Whittaker, G. C.; Burshtyn, D. N.; Orr, S. J.; Quigley, L.; Hodge, D. L.; Pascal, R.; Zhang, W. G.; McVicar, D. W.
  3. Blood. 2008 112(7): 2869-2877.
  1. 9.   Structure-assisted discovery of Variola major H1 phosphatase inhibitors
  2. Phan, J.; Tropea, J. E.; Waugh, D. S.
  3. Acta Crystallographica Section D-Biological Crystallography. 2007, Jun; 63: 698-704.
  1. 10.   CD33 responses are blocked by SOCS3 through accelerated proteasomal-mediated turnover
  2. Orr, S. J.; Morgan, N. M.; Elliott, J.; Burrows, J. F.; Scott, C. J.; McVicar, D. W.; Johnston, J. A.
  3. Blood. 2007, Feb; 109(3): 1061-1068.
  1. 11.   PM-20, a novel inhibitor of Cdc25A, induces extracellular signal-regulated kinase 1/2 phosphorylation and inhibits hepatocellular carcinoma growth in vitro and in vivo
  2. Kar, S.; Wang, M. F.; Yao, W.; Michejda, C. J.; Carr, B. I.
  3. Molecular Cancer Therapeutics. 2006, Jun; 5(6): 1511-1519.
  1. 12.   A glutathione S-transferase pi-activated prodrug causes kinase activation concurrent with S-glutathionylation of proteins
  2. Townsend, D. M.; Findlay, V. J.; Fazilev, F.; Ogle, M.; Fraser, J.; Saavedra, J. E.; Ji, X. H.; Keefer, L. K.; Tew, K. D.
  3. Molecular Pharmacology. 2006, FEB; 69(2): 501-508.
  1. 13.   Design and synthesis of phosphonodifluoromethyl phenylalanine (F(2)Pmp): A useful phosphotyrosyl mimetic
  2. Burke, T. R.
  3. Current Topics in Medicinal Chemistry. 2006 6(14): 1465-1471.
  1. 14.   Evidence for the involvement of tyrosine kinase ZAP 70 in nuclear retinoid receptor-dependent transactivation in T lymphocytes
  2. Ishaq, M.; DeGray, G.; Natarajan, V.
  3. Journal of Biological Chemistry. 2005, OCT 7; 280(40): 34152-34158.
  1. 15.   A one-step synthesis of N-alpha-Fmoc-4-O-[O ',O ''-di-tert-butyl-2-(2-fluoromalonyl)]-L-tyrosine from commercially available starting material
  2. Kang, S. U.; Burke, T. R.
  3. Tetrahedron Letters. 2004, NOV 15; 45(47): 8611-8613.
  1. 16.   Macrocyclization in the design of non-phosphorus-containing Grb2 SH2 domain-binding ligands
  2. Shi, Z. D.; Wei, C. Q.; Lee, K. O.; Liu, H. P.; Zhang, M. C.; Araki, T.; Roberts, L. R.; Worthy, K. M.; Fisher, R. J.; Neel, B. G.; Kelley, J. A.; Yang, D. J.; Burke, T. R.
  3. Journal of Medicinal Chemistry. 2004 47(8): 2166-2169.
  1. 17.   Enantioselective synthesis of (S)-3-carboxy-4-((carboxy)difluoromethyl)phenylalanine in protected form and its incorporation into a PTP-1B-directed tripeptide
  2. Kang, S. U.; Yang, G.; Li, W.; Zhang, Z. Y.; Burke, T. R.
  3. Chemistry & Biodiversity. 2004 1(4): 626-633.
  1. 18.   Cbl-3-deficient mice exhibit normal epithelial development
  2. Griffiths, E. K.; Sanchez, O.; Mill, P.; Krawczyk, C.; Hojilla, C. V.; Rubin, E.; Nau, M. M.; Khokha, R.; Lipkowitz, S.; Hui, C. C.; Penninger, J. M.
  3. Molecular and Cellular Biology. 2003 23(21): 7708-7718.
  1. 19.   Synthesis, anticancer activity, and inhibition of tubulin polymerization by conformationally restricted analogues of lavendustin A
  2. Mu, F. R.; Hamel, E.; Lee, D. J.; Pryor, D. E.; Cushman, M.
  3. Journal of Medicinal Chemistry. 2003 46(9): 1670-1682.
  1. 20.   Synthesis of a phosphotyrosyl analogue having X-1, X-2 and phi angles constrained to values observed for an SH2 domain-bound phosphotyrosyl residue
  2. Wang, X. Z.; Yao, Z. J.; Liu, H. P.; Zhang, M. C.; Yang, D. J.; George, C.; Burke, T. R.
  3. Tetrahedron. 2003 59(32): 6087-6093.
  1. 21.   The role of glycosphingolipids in HIV signaling, entry and pathogenesis
  2. Viard, M.; Parolini, I.; Rawat, S. S.; Fecchi, K.; Sargiacomo, M.; Puri, A.; Blumenthal, R.
  3. Glycoconjugate Journal. 2003 20(3): 213-222.
  1. 22.   Stat5 synergizes with T cell receptor/antigen stimulation in the development of lymphoblastic lymphoma
  2. Kelly, J. A.; Spolski, R.; Kovanen, P. E.; Suzuki, T.; Bollenbacher, J.; Pise-Masison, C. A.; Radonovich, M. F.; Lee, S.; Jenkins, N. A.; Copeland, N. G.; Morse, H. C.; Leonard, W. J.
  3. Journal of Experimental Medicine. 2003 198(1): 79-89.
  1. 23.   Tripeptide inhibitors of Yersinia protein-tyrosine phosphatase as potential leads for therapeutic development against plague ("black death")
  2. Lee, K.; Phan, J.; Wu, L.; Waugh, D. S.; Zhang, Z. Y.; Burke, T. R.
  3. Abstracts of Papers of the American Chemical Society. 2003 225(Part 2): U182-U182.
  1. 24.   The dual specificity JKAP specifically activates the c-Jun N- terminal kinase pathway
  2. Chen, A. J.; Zhou, G. S.; Juan, T.; Colicos, S. M.; Cannon, J. P.; Cabriera-Hansen, M.; Meyer, C. F.; Jurecic, R.; Copeland, N. G.; Gilbert, D. J.; Jenkins, N. A.; Fletcher, F.; Tan, T. H.; Belmont, J. W.
  3. Journal of Biological Chemistry. 2002 277(39): 36592-36601.
  1. 25.   Aberrant DAP12 signaling in the 129 strain of mice: Implications for the analysis of gene-targeted mice
  2. McVicar, D. W.; Winkler-Pickett, R.; Taylor, L. S.; Makrigiannis, A.; Bennett, M.; Anderson, S. K.; Ortaldo, J. R.
  3. Journal of Immunology. 2002 169(4): 1721-1728.
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