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  1. 1.   The DNA binding and 3'-end preferential activity of human tyrosyl-DNA phosphodiesterase
  2. Dexheimer, T. S.; Stephen, A. G.; Fivash, M. J.; Fisher, R. J.; Pommier, Y.
  3. Nucleic Acids Research. 2010, Apr; 38(7): 2444-2452.
  1. 2.   4-Pregnen-21-ol-3,20-dione-21-(4-bromobenzenesufonate) (NSC 88915) and Related Novel Steroid Derivatives as Tyrosyl-DNA Phosphodiesterase (Tdp1) Inhibitors
  2. Dexheimer, T. S.; Gediya, L. K.; Stephen, A. G.; Weidlich, I.; Antony, S.; March, C.; Interthal, H.; Nicklaus, M.; Fisher, R. J.; Njar, V. C.; Pommier, Y.
  3. Journal of Medicinal Chemistry. 2009 52(22): 7122-7131.
  1. 3.   Novel high-throughput electrochemiluminescent assay for identification of human tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors and characterization of furamidine (NSC 305831) as an inhibitor of Tdp1
  2. Antony, S.; March, C.; Stephen, A. G.; Thibaut, L.; Agama, K. K.; Fisher, R. J.; Pommier, Y.
  3. Nucleic Acids Research. 2007 35(13): 4474-4484.
  1. 4.   A mutant ataxin-3 putative-cleavage fragment in brains of Machado-Joseph disease patients and transgenic mice is cytotoxic above a critical concentration
  2. Goti, D.; Katzen, S. M.; Mez, J.; Kurtis, N.; Kiluk, J.; Ben-Haiem, L.; Jenkins, N. A.; Copeland, N. G.; Kakizuka, A.; Sharp, A. H.; Ross, C. A.; Mouton, P. R.; Colomer, V.
  3. Journal of Neuroscience. 2004, NOV 10; 24(45): 10266-10279.
  1. 5.   Unlocking the code of 14-3-3
  2. Dougherty, M. K.; Morrison, D. K.
  3. Journal of Cell Science. 2004 117(10): 1875-1884.
  1. 6.   Distinct behavioral and neuropathological abnormalities in transgenic mouse models of HD and DRPLA
  2. Schilling, G.; Jinnah, H. A.; Gonzales, V.; Coonfield, M. L.; Kim, Y.; Wood, J. D.; Price, D. L.; Li, X. J.; Jenkins, N.; Copeland, N.; Moran, T.; Ross, C. A.; Borchelt, D. R.
  3. Neurobiology of Disease. 2001 8(3): 405-418.
  1. 7.   Nuclear accumulation of truncated atrophin-1 fragments in a transgenic mouse model of DRPLA
  2. Schilling, G.; Wood, J. D.; Kui, D. A.; Slunt, H. H.; Gonzales, V.; Yamada, M.; Cooper, J. K.; Margolis, R. L.; Jenkins, N. A.; Copeland, N. G.; Takahashi, H.; Tsuji, S.; Price, D. L.; Borchelt, D. R.; Ross, C. A.
  3. Neuron. 1999 24(1): 275-286.
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