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  1. 1.   ERK signaling promotes resistance to TRK kinase inhibition in NTRK fusion-driven glioma mouse models
  2. Schmid, Sebastian; Russell, Zachary R; Shimura Yamashita,Alex; West, Madeline E; Parrish, Abigail G; Walker, Julia; Rudoy, Dmytro; Yan, James Z; Quist, David C; Gessesse, Betemariyam N; Alvinez, Neriah; Hill, Kimberly D; Anderson,Larry; Cimino, Patrick J; Kumasaka, Debra K; Parchment,Ralph; Holland, Eric C; Szulzewsky, Frank
  3. Cell Reports. 2024, Oct 03; 43(10): 114829.
  1. 2.   Lessons learned: establishing a CLIA-equivalent laboratory for targeted mass spectrometry assays - navigating the transition from research to clinical practice
  2. Han, Chia-Li; Lai, Chi-Ting; Reyes, Aaron James; Yang, Hao-Chin; Lu, Jin-Ying; Shih, Shyang-Rong; Chen, Kuen-Yuan; Hoofnagle, Andrew N; Yu, Sung-Liang; Bocik, William; Hiltke, Tara; Chiu, Huan-Chi; Wan, Ching-Yi; Rodriguez, Henry; Zhang, Victoria; Chen, Yu-Ju
  3. Clinical Proteomics. 2024, Feb 22; 21(1): 12.
  1. 3.   Pharmacodynamic effects of the PARP inhibitor talazoparib (MDV3800, BMN 673) in patients with BRCA-mutated advanced solid tumors
  2. Mittra, Arjun; Coyne, Geraldine H O' Sullivan; Zlott, Jennifer; Kummar, Shivaani; Meehan, Robert; Rubinstein, Lawrence; Juwara,Lamin; Wilsker,Deborah; Ji,Jay; Miller,Brandon; Navas, Tony; Ferry-Galow,Katherine; Voth,Andrea; Chang,Ting-Chia; Jiwani,Shahanawaz; Parchment,Ralph; Doroshow, James H; Chen, Alice P
  3. Cancer Chemotherapy and Pharmacology. 2023, Nov 27;
  1. 4.   PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer
  2. Torres-Ayuso, Pedro; Katerji,Meghri; Mehlich, Dawid; Lookingbill, Sophia A; Sabbasani, Venkata R; Liou, Hope; Casillas, Andrea L; Chauhan, Shailender S; Serwa, Remigiusz; Rubin,Maxine; Marusiak, Anna A; Swenson, Rolf E; Warfel, Noel A; Brognard,John
  3. Cell Chemical Biology. 2023, Nov 16;
  1. 5.   Methotrexate-based PROTACs as DHFR-specific chemical probes
  2. Rana, Sandeep; Dranchak, Patricia; Dahlin, Jayme L; Lamy, Laurence; Li,Wenqing; Oliphant, Erin; Shrimp, Jonathan H; Rajacharya, Girish H; Tharakan, Ravi; Holland, David O; Whitten, Apryl S; Wilson, Kelli M; Singh, Pankaj K; Durum,Scott; Tao, Dingyin; Rai, Ganesha; Inglese, James
  3. Cell Chemical Biology. 2023, Oct 17;
  1. 6.   Targeted Mass Spectrometry Enables Quantification of Novel Pharmacodynamic Biomarkers of ATM Kinase Inhibition
  2. Whiteaker, Jeffrey R; Wang, Tao; Zhao, Lei; Schoenherr, Regine M; Kennedy, Jacob J; Voytovich, Ulianna; Ivey, Richard G; Huang, Dongqing; Lin, Chenwei; Colantonio,Simona; Caceres,Tessa; Roberts,Rhonda; Knotts,Joseph; Kaczmarczyk,Jan; Blonder,Josip; Reading,Joshua; Richardson, Christopher W; Hewitt, Stephen M; Garcia-Buntley,Stephanie; Bocik,William; Hiltke, Tara; Rodriguez, Henry; Harrington, Elizabeth A; Barrett, J Carl; Lombardi, Benedetta; Marco-Casanova, Paola; Pierce, Andrew J; Paulovich, Amanda G
  3. Cancers. 2021, Aug; 13(15):
  1. 7.   Yuanhuacine Is a Potent and Selective Inhibitor of the Basal-Like 2 Subtype of Triple Negative Breast Cancer with Immunogenic Potential
  2. Fermaintt, Charles S.; Peramuna, Thilini; Cai, Shengxin; Takahashi-Ruiz, Leila; Essif, Jacob Nathaniel; Grant, Corena V.; O'Keefe,Barry; Mooberry, Susan L.; Cichewicz, Robert H.; Risinger, April L.
  3. Cancers. 2021, JUN; 13(11):
  1. 8.   Structure of SARS-CoV-2 Spike Glycoprotein for Therapeutic and Preventive Target
  2. Hong, Jaewoo; Jhun, Hyunjhung; Choi, Yeo-Ok; Taitt, Afeisha S.; Bae, Suyoung; Lee, Youngmin; Song, Chang-seon; Yeom, Su Cheong; Kim, Soohyun
  3. Immune Network. 2021, Feb 19; 21(1):
  1. 9.   Molecular Landscape and Actionable Alterations in a Genomically Guided Cancer Clinical Trial: National Cancer Institute Molecular Analysis for Therapy Choice (NCI-MATCH)
  2. Flaherty, Keith T; Gray, Robert J; Chen, Alice P; Li, Shuli; McShane, Lisa M; Patton, David; Hamilton, Stanley R; Williams,Mickey; Iafrate, A John; Sklar, Jeffrey; Mitchell, Edith P; Harris, Lyndsay N; Takebe, Naoko; Sims,David; Coffey,Brent; Fu,Tony; Routbort, Mark; Zwiebel, James A; Rubinstein, Larry V; Little, Richard F; Arteaga, Carlos L; Comis, Robert; Abrams, Jeffrey S; O'Dwyer, Peter J; Conley, Barbara A
  3. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2020, NOV 20; 38(33): pii: JCO1903010.
  1. 10.   Nanostructured Lipid Carriers as Potential Drug Delivery Systems for Skin disorders
  2. Waghule, Tejashree; Rapalli, Vamshi Krishna; Gorantla, Srividya; Saha, Ranendra Narayan; Dubey, Sunil Kumar; Puri,Anu; Singhvi, Gautam
  3. Current pharmaceutical design. 2020, Jun 14; 26(36): 4569-4579.
  1. 11.   T-Cell Deletion of MyD88 Connects IL17 and I kappa B zeta to RAS Oncogenesis
  2. Cataisson, Christophe; Salcedo, Rosalba; Michalowski, Aleksandra M.; Klosterman, Mary; Naik, Shruti; Li, Luowei; Pan, Michelle J.; Sweet, Amalia; Chen, Jin-Qiu; Kostecka, Laurie G.; Karwan,Megan; Smith, Loretta; Dai,Ren; Stewart, C. Andrew; Lyakh, Lyudmila; Hsieh,Wang-Ting; Khan, Asra; Yang, Howard; Lee, Maxwell; Trinchieri, Giorgio; Yuspa, Stuart H.
  3. MOLECULAR CANCER RESEARCH. 2019, AUG; 17(8): 1759-1773.
  1. 12.   An admixture mapping meta-analysis implicates genetic variation at 18q21 with asthma susceptibility in Latinos
  2. Gignoux, Chris R; Torgerson, Dara G; Pino-Yanes, Maria; Uricchio, Lawrence H; Galanter, Joshua; Roth, Lindsey A; Eng, Celeste; Hu, Donglei; Nguyen, Elizabeth A; Huntsman, Scott; Mathias, Rasika A; Kumar, Rajesh; Rodriguez-Santana, Jose; Thakur, Neeta; Oh, Sam S; McGarry, Meghan; Moreno-Estrada, Andres; Sandoval, Karla; Winkler, Cheryl; Seibold, Max A; Padhukasahasram, Badri; Conti, David V; Farber, Harold J; Avila, Pedro; Brigino-Buenaventura, Emerita; Lenoir, Michael; Meade, Kelley; Serebrisky, Denise; Borrell, Luisa N; Rodriguez-Cintron, William; Thyne, Shannon; Joubert, Bonnie R; Romieu, Isabelle; Levin, Albert M; Sienra-Monge, Juan-Jose; Del Rio-Navarro, Blanca Estela; Gan, Weiniu; Raby, Benjamin A; Weiss, Scott T; Bleecker, Eugene; Meyers, Deborah A; Martinez, Fernando J; Gauderman, W James; Gilliland, Frank; London, Stephanie J; Bustamante, Carlos D; Nicolae, Dan L; Ober, Carole; Sen, Saunak; Barnes, Kathleen; Williams, L Keoki; Hernandez, Ryan D; Burchard, Esteban G
  3. Journal of Allergy and Clinical Immunology. 2019, Mar; 143(3): 957-969.
  1. 13.   Doxorubicin-resistant pleomorphic liposarcoma with PDGFRA gene amplification is targeted and regressed by pazopanib in a patient-derived orthotopic xenograft mouse model
  2. Kiyuna, Tasuku; Murakami, Takashi; Tome, Yasunori; Igarashi, Kentaro; Kawaguchi, Kei; Miyake, Kentaro; Miyake, Masuyo; Li, Yunfeng; Nelson, Scott D; Dry, Sarah M; Singh, Arun S; Russell, Tara A; Singh, Shree Ram; Kanaya, Fuminori; Eilber, Fritz C; Hoffman, Robert M
  3. Tissue & Cell. 2018, Aug; 53: 30-36.
  1. 14.   Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation
  2. Zhou, Tongqing; Doria-Rose, Nicole A; Cheng, Cheng; Stewart-Jones, Guillaume B E; Chuang, Gwo-Yu; Chambers, Michael; Druz, Aliaksandr; Geng, Hui; McKee, Krisha; Kwon, Young Do; O'Dell, Sijy; Sastry, Mallika; Schmidt, Stephen D; Xu, Kai; Chen, Lei; Chen, Rita E; Louder, Mark K; Pancera, Marie; Wanninger, Timothy G; Zhang, Baoshan; Zheng, Anqi; Farney, S Katie; Foulds, Kathryn E; Georgiev, Ivelin S; Joyce, M Gordon; Lemmin, Thomas; Narpala, Sandeep; Rawi, Reda; Soto, Cinque; Todd, John-Paul; Shen, Chen-Hsiang; Tsybovsky, Yaroslav; Yang, Yongping; Zhao, Peng; Haynes, Barton F; Stamatatos, Leonidas; Tiemeyer, Michael; Wells, Lance; Scorpio, Diana G; Shapiro, Lawrence; McDermott, Adrian B; Mascola, John R; Kwong, Peter D
  3. Cell Reports. 2017, Apr 25; 19(4): 719-732.
  1. 15.   Mesoderm-specific Stat3 deletion affects expression of Sox9 yielding Sox9-dependent phenotypes
  2. Hall, Michael; Murray, Caroline A.; Valdez, Michael J.; Perantoni, Alan
  3. PLOS GENETICS. 2017, Feb 6; 13(2): e1006610.
  1. 16.   Discovery and preclinical evaluation of 7-benzyl-N-(substituted)-pyrrolo [3,2-d]pyrimidin-4-amines as single agents with microtubule targeting effects along with triple -acting angiokinase inhibition as antitumor agents
  2. Pavana, Roheeth Kumar; Choudhary, Shruti; Bastian, Anja; Ihnat, Michael A.; Bai, Ruoli; Hamel, Ernest; Gangjee, Aleem
  3. BIOORGANIC & MEDICINAL CHEMISTRY. 2017, Jan 15; 25(2): 545-556.
  1. 17.   Ultrasensitive single-genome sequencing: accurate, targeted, next generation sequencing of HIV-1 RNA.
  2. Boltz, Valerie; Rausch, Jason; Shao, Wei; Hattori, Takaaki; Luke, Brian; Maldarelli, Frank; Mellors, John W; Kearney, Mary F; Coffin, John
  3. Retrovirology. 2016, Dec 20; 13(1): 87.
  1. 18.   Complexity in the signaling network: insights from the use of targeted inhibitors in cancer therapy
  2. Logue, J. S.; Morrison, D. K.
  3. Genes & Development. 2012, Apr; 26(7): 641-650.
  1. 19.   Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors
  2. Leese, M. P.; Jourdan, F.; Dohle, W.; Kimberley, M. R.; Thomas, M. P.; Bai, R. L.; Hamel, E.; Ferrandis, E.; Potter, B. V. L.
  3. Acs Medicinal Chemistry Letters. 2012, Jan; 3(1): 5-9.
  1. 20.   Inhibition of Polo-like kinase 1 prevents the growth of metastatic breast cancer cells in the brain
  2. Qian, Y. Z.; Hua, E.; Bisht, K.; Woditschka, S.; Skordos, K. W.; Liewehr, D. J.; Steinberg, S. M.; Brogi, E.; Akram, M. M.; Killian, J. K.; Edelman, D. C.; Pineda, M.; Scurci, S.; Degenhardt, Y. Y.; Laquerre, S.; Lampkin, T. A.; Meltzer, P. S.; Camphausen, K.; Steeg, P. S.; Palmieri, D.
  3. Clinical & Experimental Metastasis. 2011, Dec; 28(8): 899-908.
  1. 21.   Probing Cellular Processes with Oligo-Mediated Recombination and Using the Knowledge Gained to Optimize Recombineering
  2. Sawitzke, J. A.; Costantino, N.; Li, X. T.; Thomason, L. C.; Bubunenko, M.; Court, C.; Court, D. L.
  3. Journal of Molecular Biology. 2011, Mar; 407(1): 45-59.
  1. 22.   Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling
  2. Vaegter, C. B.; Jansen, P.; Fjorback, A. W.; Glerup, S.; Skeldal, S.; Kjolby, M.; Richner, M.; Erdmann, B.; Nyengaard, J. R.; Tessarollo, L.; Lewin, G. R.; Willnow, T. E.; Chao, M. V.; Nykjaer, A.
  3. Nature Neuroscience. 2011, Jan; 14(1): 54-U78.
  1. 23.   STAT1 activation regulates proliferation and differentiation of renal progenitors
  2. Wang, H.; Yang, Y.; Sharma, N.; Tarasova, N. I.; Timofeeva, O. A.; Winkler-Pickett, R. T.; Tanigawa, S.; Perantoni, A. O.
  3. Cellular Signalling. 2010, Nov; 22(11): 1717-1726.
  1. 24.   Antitumor Activity of Hu14.18-IL2 in Patients With Relapsed/Refractory Neuroblastoma: A Children's Oncology Group (COG) Phase II Study
  2. Shusterman, S.; London, W. B.; Gillies, S. D.; Hank, J. A.; Voss, S. D.; Seeger, R. C.; Reynolds, C. P.; Kimball, J.; Albertini, M. R.; Wagner, B.; Gan, J.; Eickhoff, J.; DeSantes, K. B.; Cohn, S. L.; Hecht, T.; Gadbaw, B.; Reisfeld, R. A.; Maris, J. M.; Sondel, P. M.
  3. Journal of Clinical Oncology. 2010, Nov; 28(33): 4969-4975.
  1. 25.   Plant Natural Products in Anticancer Drug Discovery
  2. Grothaus, P. G.; Cragg, G. M.; Newman, D. J.
  3. Current Organic Chemistry. 2010, Oct; 14(16): 1781-1791.
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