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  1. 1.   Attenuation of aggressive tumor progression of anaplastic thyroid cancer by p53
  2. Hwang, Eunmi; Kruhlak, Michael; Wong,Nathan; Chari,Raj; Kimura, Takahito; Cheng, Sheue-Yann
  3. American Journal of Cancer Research. 2024 14(9): 4429-4444.
  1. 2.   Cancer and Autism: How PTEN Mutations Degrade Function at the Membrane and Isoform Expression in the Human Brain
  2. Jang,Hyunbum; Chen, Jiaye; Iakoucheva, Lilia M; Nussinov,Ruth
  3. Journal of Molecular Biology. 2023, Dec 15; 435(24): 168354.
  1. 3.   Germline and somatic inactivating FLCN variants in parathyroid cancer and atypical parathyroid tumors
  2. Jha, Smita; Welch, James; Tora, Rana; Lack, Justin; Warner,Andrew; Del Rivero, Jaydira; Sadowski, Samira M; Nilubol, Naris; Schmidt,Laura; Linehan, W Marston; Weinstein, Lee S; Simonds, William F; Agarwal, Sunita K
  3. The Journal of Clinical Endocrinology and Metabolism. 2023, Mar 20;
  1. 4.   Thymidylate synthase accelerates Men1-mediated pancreatic tumor progression and reduces survival
  2. Vijayakurup, Vinod; Maeng, Kyungah; Lee, Hye Seung; Meyer, Benjamin S; Burkett,Sandra; Nawab, Akbar; Dougherty, Michael W; Jobin, Christian; Mahmud, Iqbal; Garrett, Timothy J; Feely, Michael; Lee, Kyoung Bun; Kaye, Frederic J; Guijarro, Maria V; Zajac-Kaye, Maria
  3. JCI Insight. 2022, Sep 01; 7(19):
  1. 5.   The tumor suppressor activity of DLC1 requires the interaction of its START domain with Phosphatidylserine, PLCD1, and Caveolin-1
  2. Sanchez-Solana, Beatriz; Wang, Dunrui; Qian, Xiaolan; Velayoudame, Parthibane; Simanshu,Dhirendra; Acharya,Jairaj; Lowy, Douglas R
  3. Molecular Cancer. 2021, Nov 02; 20(1):
  1. 6.   Promoterless Transposon Mutagenesis Drives Solid Cancers via Tumor Suppressor Inactivation
  2. Aiderus, Aziz; Contreras-Sandoval, Ana M; Meshey, Amanda L; Newberg, Justin Y; Ward, Jerrold M; Swing,Debbie; Copeland, Neal G; Jenkins, Nancy A; Mann, Karen M; Mann, Michael B
  3. Cancers. 2021, Jan 09; 13(2):
  1. 7.   Nitric Oxide Donor DETA/NO Inhibits the Growth of Endometrial Cancer Cells by Upregulating the Expression of RASSF1 and CDKN1A
  2. Waheed, Sana; Cheng, Robert Ys; Casablanca, Yovanni; Maxwell, G Larry; Wink,David; Syed, Viqar
  3. Molecules (Basel, Switzerland). 2019, Oct 16; 24(20): pii: E3722..
  1. 8.   Orange is the new black: Kinases are the new master regulators of tumor suppression
  2. An,Elvira; Brognard,John
  3. IUBMB LIFE. 2019, JUN; 71(6): 738-748.
  1. 9.   Cytoglobin inhibits migration through PI3K/AKT/mTOR pathway in fibroblast cells.
  2. Demirci, Selami; Dogan, Aysegul; Apdik, Hüseyin; Tuysuz, Emre Can; Gulluoglu, Sukru; Bayrak, Omer Faruk; Sahin, Fikrettin
  3. Molecular and cellular biochemistry. 2018, Jan; 437(1-2): 133-142.
  1. 10.   Epigenetic silencing of PRSS3 provides growth and metastasis advantage for human hepatocellular carcinoma
  2. Lin, Bonan; Zhou, Xiaomeng; Lin, Shuye; Wang, Xiaoyue; Zhang, Meiying; Cao, Baoping; Dong, Yan; Yang, Shuai; Wang, Jiming; Guo, Mingzhou; Huang, Jiaqiang
  3. Journal of Molecular Medicine (Berlin, Germany). 2017, Nov; 95(11): 1237-1249.
  1. 11.   Mechanisms that drive inflammatory tumor microenvironment, tumor heterogeneity, and metastatic progression.
  2. Yang, Li; Lin, P Charles
  3. Seminars in cancer biology. 2017, Aug 03; pii: S1044-579X(17)30205-5.
  1. 12.   Neuralized1 causes apoptosis and downregulates Notch target genes in medulloblastoma
  2. Teider, N.; Scott, D. K.; Neiss, A.; Weeraratne, S. D.; Amani, V. M.; Wang, Y. F.; Marquez, V. E.; Cho, Y. J.; Pomeroy, S. L.
  3. Neuro-Oncology. 2010, Dec; 12(12): 1244-+.
  1. 13.   miR-23b*targets proline oxidase, a novel tumor suppressor protein in renal cancer
  2. Liu, W.; Zabirnyk, O.; Wang, H.; Shiao, Y. H.; Nickerson, M. L.; Khalil, S.; Anderson, L. M.; Perantoni, A. O.; Phang, J. M.
  3. Oncogene. 2010, Sep 2; 29(35): 4914-4924.
  1. 14.   Proline Metabolism and Microenvironmental Stress
  2. Phang, J. M.; Liu, W.; Zabirnyk, O.
  3. Annual review of nutrition. 2010, Aug 21; 30: 441-463.
  1. 15.   A mouse model of chondrocyte-specific somatic mutation reveals a role for Ext1 loss of heterozygosity in multiple hereditary exostoses
  2. Matsumoto, K.; Irie, F.; Mackem, S.; Yamaguchi, Y.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2010, Jun; 107(24): 10932-10937.
  1. 16.   C/EBP ? targets cyclin D1 for proteasome-mediated degradation via induction of CDC27/APC3 expression
  2. Pawar, S. A.; Sarkar, T. R.; Balamurugan, K.; Sharan, S.; Wang, J.; Zhang, Y. H.; Dowdy, S. F.; Huang, A. M.; Sterneck, E.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2010, May 18; 107(20): 9210-9215.
  1. 17.   Development of a High-Throughput Cell-Based Reporter Assay to Identify Stabilizers of Tumor Suppressor Pdcd4
  2. Blees, J. S.; Schmid, T.; Thomas, C. L.; Baker, A. R.; Benson, L.; Evans, J. R.; Goncharova, E. I.; Colburn, N. H.; McMahon, J. B.; Henrich, C. J.
  3. Journal of Biomolecular Screening. 2010, Jan; 15(1): 21-29.
  1. 18.   Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2
  2. Hasumi, Y.; Baba, M.; Ajima, R.; Hasumi, H.; Valera, V. A.; Klein, M. E.; Haines, D. C.; Merino, M. J.; Hong, S. B.; Yamaguchi, T. P.; Schmidt, L. S.; Linehan, W. M.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2009 106(44): 18722-18727.
  1. 19.   Identification and characterization of a novel folliculin-interacting protein FNIP2
  2. Hasumi, H.; Baba, M.; Hong, S. B.; Hasumi, Y.; Huang, Y.; Yao, M.; Valera, V. A.; Linehan, W. M.; Schmidt, L. S.
  3. Gene. 2008 415(1-2): 60-67.
  1. 20.   Allosteric effects in the marginally stable von Hippel-Lindau tumor suppressor protein and allostery-based rescue mutant design
  2. Liu, J.; Nussinov, R.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2008 105(3): 901-906.
  1. 21.   Proline oxidase, a p53-induced gene, targets COX-2/PGE(2) signaling to induce apoptosis and inhibit tumor growth in colorectal cancers
  2. Liu, Y.; Borchert, G. L.; Surazynski, A.; Phang, J. M.
  3. Oncogene. 2008 27(53): 6729-6737.
  1. 22.   Endosomal entry regulates Notch receptor activation in Drosophila melanogaster
  2. Vaccari, T.; Lu, H.; Kanwar, R.; Fortin, M. E.; Bilder, D.
  3. Journal of Cell Biology. 2008 180(4): 755-762.
  1. 23.   BRCA1a has antitumor activity in TN breast, ovarian and prostate cancers
  2. Yuli, C.; Shao, N.; Rao, R.; Aysola, P.; Reddy, V.; Oprea-llies, G.; Lee, L.; Okoli, J.; Partridge, E.; Reddy, E. S. P.; Rao, V. N.
  3. Oncogene. 2007, Sep; 26(41): 6031-6037.
  1. 24.   Functional studies of the chromosome 3p21.3 candidate tumor suppressor gene BLU/ZMYND10 in nasopharyngeal carcinoma
  2. Yau, W. L.; Lung, H. L.; Zabarovsky, E. R.; Lerman, M. I.; Sham, J. S. T.; Chua, D. T. T.; Tsao, S. W.; Stanbridge, E. J.; Lung, M. L.
  3. International Journal of Cancer. 2006, Dec; 119(12): 2821-2826.
  1. 25.   Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling
  2. Baba, M.; Hong, S. B.; Sharma, N.; Warren, M. B.; Nickerson, M. L.; Iwamatsu, A.; Esposito, D.; Gillette, W. K.; Hopkins, R. F.; Hartley, J. L.; Furihata, M.; Oishi, S.; Zhen, W.; Burke, T. R.; Linehan, W. M.; Schmidt, L. S.; Zbar, B.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2006, Oct; 103(42): 15552-15557.
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