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  1. 1.   Targeting Protein-Protein Interactions of Tyrosine Phosphatases with Microarrayed Fragment Libraries Displayed on Phosphopeptide Substrate Scaffolds
  2. Hogan, Megan; Bahta, Medhanit; Tsuji, Kohei; Nguyen, Trung X.; Cherry,Scott; Lountos,George; Tropea,Joseph; Zhao, Bryan M.; Zhao,Xue Zhi; Waugh,David; Burke,Terrence; Ulrich, Robert G.
  3. ACS COMBINATORIAL SCIENCE. 2019, Mar 11; 21: 158-170.
  1. 2.   High-resolution crystal structures of the D1 and D2 domains of protein tyrosine phosphatase epsilon for structure-based drug design
  2. Lountos, George; Raran-Kurussi, Sreejith; Zhao, Bryan M; Dyas, Beverly K; Burke, Terrence; Ulrich, Robert G; Waugh, David
  3. Acta crystallographica. Section D, Structural biology. 2018, Oct 01; 74(Pt 10): 1015-1026.
  1. 3.   Structure of human dual-specificity phosphatase 27 at 2.38 angstrom resolution
  2. Lountos, G. T.; Tropea, J. E.; Waugh, D. S.
  3. Acta Crystallographica Section D-Biological Crystallography. 2011, May; 67: 471-479.
  1. 4.   Two-tiered Approach Identifies a Network of Cancer and Liver Disease-related Genes Regulated by miR-122
  2. Boutz, D. R.; Collins, P. J.; Suresh, U.; Lu, M. Z.; Ramirez, C. M.; Fernandez-Hernando, C.; Huang, Y. F.; Abreu, R. D.; Le, S. Y.; Shapiro, B. A.; Liu, A. M.; Luk, J. M.; Aldred, S. F.; Trinklein, N. D.; Marcotte, E. M.; Penalva, L. O. F.
  3. Journal of Biological Chemistry. 2011, May; 286(20): 18066-18078.
  1. 5.   Optimization of a Cyclic Peptide Inhibitor of Ser/Thr Phosphatase PPM1D (Wip1)
  2. Hayashi, R.; Tanoue, K.; Durell, S. R.; Chatterjee, D. K.; Jenkins, L. M. M.; Appella, D. H.; Appella, E.
  3. Biochemistry. 2011, May; 50(21): 4537-4549.
  1. 6.   A rapid oxime linker-based library approach to identification of bivalent inhibitors of the Yersinia pestis protein-tyrosine phosphatase, YopH
  2. Liu, F.; Hakami, R. M.; Dyas, B.; Bahta, M.; Lountos, G. T.; Waugh, D. S.; Ulrich, R. G.; Burke, T. R.
  3. Bioorganic & Medicinal Chemistry Letters. 2010, May; 20(9): 2813-2816.
  1. 7.   The metastasis-associated gene S100A4 is a novel target of beta-catenin/T-cell factor signaling in colon cancer
  2. Stein, U.; Arlt, F.; Walther, W.; Smith, J.; Waldman, T.; Harris, E. D.; Mertins, S. D.; Heizmann, C. W.; Allard, D.; Birchmeier, W.; Schlag, P. M.; Shoemaker, R. H.
  3. Gastroenterology. 2006, Nov; 131(5): 1486-1500.
  1. 8.   A glutathione S-transferase pi-activated prodrug causes kinase activation concurrent with S-glutathionylation of proteins
  2. Townsend, D. M.; Findlay, V. J.; Fazilev, F.; Ogle, M.; Fraser, J.; Saavedra, J. E.; Ji, X. H.; Keefer, L. K.; Tew, K. D.
  3. Molecular Pharmacology. 2006, FEB; 69(2): 501-508.
  1. 9.   Design and synthesis of phosphonodifluoromethyl phenylalanine (F(2)Pmp): A useful phosphotyrosyl mimetic
  2. Burke, T. R.
  3. Current Topics in Medicinal Chemistry. 2006 6(14): 1465-1471.
  1. 10.   Expression of hypoxia-inducible carbonic anhydrases in brain tumors
  2. Proescholdt, M. A.; Mayer, C.; Kubitza, M.; Schubert, T.; Liao, S. Y.; Stanbridge, E. J.; Ivanov, S.; Oldfield, E. H.; Brawanski, A.; Merrill, M. J.
  3. Neuro-Oncology. 2005, OCT; 7(4): 465-475.
  1. 11.   Mouse Ly49 NK receptors: balancing activation and inhibition
  2. Ortaldo, J. R.; Young, H. A.
  3. Molecular Immunology. 2005, FEB; 42(4): 445-450.
  1. 12.   Enantioselective synthesis of (S)-3-carboxy-4-((carboxy)difluoromethyl)phenylalanine in protected form and its incorporation into a PTP-1B-directed tripeptide
  2. Kang, S. U.; Yang, G.; Li, W.; Zhang, Z. Y.; Burke, T. R.
  3. Chemistry & Biodiversity. 2004 1(4): 626-633.
  1. 14.   Tripeptide inhibitors of Yersinia protein-tyrosine phosphatase as potential leads for therapeutic development against plague ("black death")
  2. Lee, K.; Phan, J.; Wu, L.; Waugh, D. S.; Zhang, Z. Y.; Burke, T. R.
  3. Abstracts of Papers of the American Chemical Society. 2003 225(Part 2): U182-U182.
  1. 15.   Phosphoryltyrosyl mimetics in the design of peptide-based signal transduction inhibitors
  2. Burke, T. R.; Yao, Z. J.; Liu, D. G.; Voigt, J.; Gao, Y.
  3. Biopolymers. 2001 60(1): 32-44.
  1. 16.   Unusual molecular architecture of the Yersinia pestis cytotoxin YopM: A leucine-rich repeat protein with the shortest repeating unit
  2. Evdokimov, A. G.; Anderson, D. E.; Routzahn, K. M.; Waugh, D. S.
  3. Journal of Molecular Biology. 2001 312(4): 807-821.
  1. 17.   Activating Ly-49D NK receptors: expression and function in relation to ontogeny and Ly-49 inhibitor receptors
  2. Ortaldo, J. R.; Winkler-Pickett, R.; Wiegand, G.
  3. Journal of Leukocyte Biology. 2000 68(5): 748-756.
  1. 18.   Induction of TNF alpha in macrophages by vanadate is dependent on activation of transcription factor NF-kappa B and free radical reactions
  2. Ye, J. P.; Ding, M.; Zhang, X. Y.; Rojanasakul, Y.; Nedospasov, S.; Vallyathan, V.; Castronova, V.; Shi, X. L.
  3. Molecular and Cellular Biochemistry. 1999 198(1-2): 193-200.
  1. 19.   Opposing actions of CSW and RasGAP modulate the strength of torso RTK signaling in the Drosophila terminal pathway
  2. Cleghon, V.; Feldmann, P.; Ghiglione, C.; Copeland, T. D.; Perrimon, N.; Hughes, D. A.; Morrison, D. K.
  3. Molecular Cell. 1998 2(6): 719-727.
  1. 20.   A Novel Human Erk Phosphatase Regulates H-Ras and V-Raf Signal Transduction
  2. Shin, D. Y.; Ishibashi, T.; Choi, T. S.; Chung, E. M.; Chung, I. Y.; Aaronson, S. A.; Bottaro, D. P.
  3. Oncogene. 1997 14(22): 2633-2639.
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