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  1. 1.   Oxime-based linker libraries as a general approach for the rapid generation and screening of multidentate inhibitors
  2. Bahta, M.; Liu, F.; Kim, S. E.; Stephen, A. G.; Fisher, R. J.; Burke, T. R.
  3. Nature Protocols. 2012, Apr; 7(4): 686-702.
  1. 2.   Utilization of Nitrophenylphosphates and Oxime-Based Ligation for the Development of Nanomolar Affinity Inhibitors of the Yersinia pestis Outer Protein H (YopH) Phosphatase
  2. Bahta, M.; Lountos, G. T.; Dyas, B.; Kim, S. E.; Ulrich, R. G.; Waugh, D. S.; Burke, T. R.
  3. Journal of Medicinal Chemistry. 2011, Apr; 54(8): 2933-2943.
  1. 3.   Loss of the Transcriptional Repressor PAG-3/Gfi-1 Results in Enhanced Neurosecretion that is Dependent on the Dense-Core Vesicle Membrane Protein IDA-1/IA-2
  2. Cai, T.; Hirai, H.; Fukushige, T.; Yu, P.; Zhang, G. F.; Notkins, A. L.; Krause, M.
  3. Plos Genetics. 2009 5(4): 1-13.
  1. 4.   Zap70 signaling pathway mediates glucocorticoid receptor-dependent transcriptional activation: role in the regulation of annexin 1 expression in T cells
  2. Ishaq, M.; DeGray, G.; Mou, K.; Aguilera, A.; Yang, J.; Lempicki, R. A.; Hazen, A.; Natarajan, V.
  3. Journal of Immunology. 2007, Sep; 179(6): 3851-3858.
  1. 5.   Structure-assisted discovery of Variola major H1 phosphatase inhibitors
  2. Phan, J.; Tropea, J. E.; Waugh, D. S.
  3. Acta Crystallographica Section D-Biological Crystallography. 2007, Jun; 63: 698-704.
  1. 6.   CD33 responses are blocked by SOCS3 through accelerated proteasomal-mediated turnover
  2. Orr, S. J.; Morgan, N. M.; Elliott, J.; Burrows, J. F.; Scott, C. J.; McVicar, D. W.; Johnston, J. A.
  3. Blood. 2007, Feb; 109(3): 1061-1068.
  1. 7.   Overproduction, purification, and biochemical characterization of the dual specificity H1 protein phosphatase encoded by variola major virus
  2. Tropea, J. E.; Phan, J.; Waugh, D. S.
  3. Protein Expression and Purification. 2006, Nov; 50(1): 31-36.
  1. 8.   Inhibition of HIV-1 replication by amphotericin B methyl ester - Selection for resistant variants
  2. Waheed, A. A.; Ablan, S. D.; Mankowski, M. K.; Cummins, J. E.; Ptak, R. G.; Schaffner, C. P.; Freed, E. O.
  3. Journal of Biological Chemistry. 2006, Sep; 281(39): 28699-28711.
  1. 9.   IL-18 as critical co-stimulatory molecules in modulating the immune response of ITAM bearing lymphocytes
  2. Ortaldo, J. R.; Young, H. A.
  3. Seminars in Immunology. 2006, Jun; 18(3): 193-196.
  1. 10.   A glutathione S-transferase pi-activated prodrug causes kinase activation concurrent with S-glutathionylation of proteins
  2. Townsend, D. M.; Findlay, V. J.; Fazilev, F.; Ogle, M.; Fraser, J.; Saavedra, J. E.; Ji, X. H.; Keefer, L. K.; Tew, K. D.
  3. Molecular Pharmacology. 2006, FEB; 69(2): 501-508.
  1. 11.   Crystal structures of a high-affinity macrocyclic peptide mimetic in complex with the Grb2 SH2 domain
  2. Phan, J.; Shi, Z. D.; Burke, T. R.; Waugh, D. S.
  3. Journal of Molecular Biology. 2005, OCT 14; 353(1): 104-115.
  1. 12.   Evidence for the involvement of tyrosine kinase ZAP 70 in nuclear retinoid receptor-dependent transactivation in T lymphocytes
  2. Ishaq, M.; DeGray, G.; Natarajan, V.
  3. Journal of Biological Chemistry. 2005, OCT 7; 280(40): 34152-34158.
  1. 13.   Regulation of human immunodeficiency virus type 1 envelope glycoprotein fusion by a membrane-interactive domain in the gp41 cytoplasmic tail
  2. Wyss, S.; Dimitrov, A. S.; Baribaud, F.; Edwards, T. G.; Blumenthal, R.; Hoxie, J. A.
  3. Journal of Virology. 2005, OCT; 79(19): 12231-12241.
  1. 14.   Virion envelope content, infectivity, and neutralization sensitivity of simian immunodeficiency virus
  2. Yuste, E.; Johnson, W.; Pavlakis, G. N.; Desrosiers, R. C.
  3. Journal of Virology. 2005, OCT; 79(19): 12455-12463.
  1. 15.   A one-step synthesis of N-alpha-Fmoc-4-O-[O ',O ''-di-tert-butyl-2-(2-fluoromalonyl)]-L-tyrosine from commercially available starting material
  2. Kang, S. U.; Burke, T. R.
  3. Tetrahedron Letters. 2004, NOV 15; 45(47): 8611-8613.
  1. 16.   Differential B cell expression of mouse Fc receptor homologs
  2. Davis, R. S.; Stephan, R. P.; Chen, C. C.; Dennis, G.; Cooper, M. D.
  3. International Immunology. 2004, SEP; 16(9): 1343-1353.
  1. 17.   Macrocyclization in the design of non-phosphorus-containing Grb2 SH2 domain-binding ligands
  2. Shi, Z. D.; Wei, C. Q.; Lee, K. O.; Liu, H. P.; Zhang, M. C.; Araki, T.; Roberts, L. R.; Worthy, K. M.; Fisher, R. J.; Neel, B. G.; Kelley, J. A.; Yang, D. J.; Burke, T. R.
  3. Journal of Medicinal Chemistry. 2004 47(8): 2166-2169.
  1. 18.   dDYRK2: a novel dual-specificity tyrosine-phosphorylation- regulated kinase in Drosophila
  2. Lochhead, P. A.; Sibbet, G.; Kinstrie, R.; Cleghon, T.; Rylatt, M.; Morrison, D. K.; Cleghon, V.
  3. Biochemical Journal. 2003 374(Part 2): 381-391.
  1. 19.   Acylsulfonamide-containing PTP1B inhibitors designed to mimic an enzyme-bound water of hydration
  2. Liu, D. G.; Gao, Y.; Voigt, J. H.; Lee, K.; Nicklaus, M. C.; Wu, L.; Zhang, Z. Y.; Burke, T. R.
  3. Bioorganic & Medicinal Chemistry Letters. 2003 13(18): 3005-3007.
  1. 20.   Structure-based design of thioether-bridged cyclic phosphopeptides binding to Grb2-SH2 domain
  2. Li, P.; Peach, M. L.; Zhang, M. C.; Liu, H. P.; Yang, D. J.; Nicklaus, M.; Roller, P. P.
  3. Bioorganic & Medicinal Chemistry Letters. 2003 13(5): 895-899.
  1. 21.   Synthesis of a phosphotyrosyl analogue having X-1, X-2 and phi angles constrained to values observed for an SH2 domain-bound phosphotyrosyl residue
  2. Wang, X. Z.; Yao, Z. J.; Liu, H. P.; Zhang, M. C.; Yang, D. J.; George, C.; Burke, T. R.
  3. Tetrahedron. 2003 59(32): 6087-6093.
  1. 22.   Stat5 synergizes with T cell receptor/antigen stimulation in the development of lymphoblastic lymphoma
  2. Kelly, J. A.; Spolski, R.; Kovanen, P. E.; Suzuki, T.; Bollenbacher, J.; Pise-Masison, C. A.; Radonovich, M. F.; Lee, S.; Jenkins, N. A.; Copeland, N. G.; Morse, H. C.; Leonard, W. J.
  3. Journal of Experimental Medicine. 2003 198(1): 79-89.
  1. 23.   Tripeptide inhibitors of Yersinia protein-tyrosine phosphatase as potential leads for therapeutic development against plague ("black death")
  2. Lee, K.; Phan, J.; Wu, L.; Waugh, D. S.; Zhang, Z. Y.; Burke, T. R.
  3. Abstracts of Papers of the American Chemical Society. 2003 225(Part 2): U182-U182.
  1. 24.   The dual specificity JKAP specifically activates the c-Jun N- terminal kinase pathway
  2. Chen, A. J.; Zhou, G. S.; Juan, T.; Colicos, S. M.; Cannon, J. P.; Cabriera-Hansen, M.; Meyer, C. F.; Jurecic, R.; Copeland, N. G.; Gilbert, D. J.; Jenkins, N. A.; Fletcher, F.; Tan, T. H.; Belmont, J. W.
  3. Journal of Biological Chemistry. 2002 277(39): 36592-36601.
  1. 25.   Docking protein SNT1 is a critical mediator of fibroblast growth factor signaling during Xenopus embryonic development
  2. Akagi, K.; Park, E. K.; Mood, K.; Daar, I. O.
  3. Developmental Dynamics. 2002 223(2): 216-228.
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