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  1. 1.   Long-acting rilpivirine (RPV LA) pre-exposure prophylaxis does not inhibit vaginal transmission of RPV-resistant HIV-1 nor select for high frequency drug resistance in humanized mice
  2. Melody, Kevin; Roy, Chandra N; Kline, Christopher; Cottrell, Mackenzie L; Evans, Dwayne; Shutt, Kathleen; Pennings, Pleuni S; Keele,Brandon; Bility, Moses; Kashuba, Angela D M; Ambrose, Zandrea
  3. Journal of virology. 2020, APR; 94(8):
  1. 2.   An intravaginal ring that releases three antiviral agents and a contraceptive blocks SHIV-RT infection, reduces HSV-2 shedding, and suppresses hormonal cycling in rhesus macaques
  2. Derby, Nina; Aravantinou, Meropi; Kenney, Jessica; Ugaonkar, Shweta R; Wesenberg, Asa; Wilk, Jolanta; Kizima, Larisa; Rodriguez, Aixa; Zhang, Shimin; Mizenina, Olga; Levendosky, Keith; Cooney, Michael L; Seidor, Samantha; Gettie, Agegnehu; Grasperge, Brooke; Blanchard, James; Piatak, Michael; Lifson, Jeffrey; Fernández-Romero, José; Zydowsky, Thomas M; Robbiani, Melissa
  3. Drug Delivery and Translational Research. 2017, Dec; 7(6): 840-858.
  1. 3.   The lectins griffithsin, cyanovirin-N and scytovirin inhibit HIV-1 binding to the DC-SIGN receptor and transfer to CD4(+) cells
  2. Alexandre, K. B.; Gray, E. S.; Mufhandu, H.; McMahon, J. B.; Chakauya, E.; O'Keefe, B. R.; Chikwamba, R.; Morris, L.
  3. Virology. 2012, Feb; 423(2): 175-186.
  1. 4.   SIVmac251 Is Inefficiently Transmitted to Rhesus Macaques by Penile Inoculation with a Single SIVenv Variant Found in Ramp-up Phase Plasma
  2. Ma, Z. M.; Keele, B. F.; Qureshi, H.; Stone, M.; DeSilva, V.; Fritts, L.; Lifson, J. D.; Miller, C. J.
  3. Aids Research and Human Retroviruses. 2011, Dec; 27(12): 1259-1269.
  1. 5.   Depletion of CD4(+) T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques
  2. Ortiz, A. M.; Klatt, N. R.; Li, B.; Yi, Y.; Tabb, B.; Hao, X. P.; Sternberg, L.; Lawson, B.; Carnathan, P. M.; Cramer, E. M.; Engram, J. C.; Little, D. M.; Ryzhova, E.; Gonzalez-Scarano, F.; Paiardini, M.; Ansari, A. A.; Ratcliffe, S.; Else, J. G.; Brenchley, J. M.; Collman, R. G.; Estes, J. D.; Derdeyn, C. A.; Silvestri, G.
  3. Journal of Clinical Investigation. 2011, Nov; 121(11): 4433-4445.
  1. 6.   Barriers to mucosal transmission of immunodeficiency viruses
  2. Keele, B. F.; Estes, J. D.
  3. Blood. 2011, Jul; 118(4): 839-846.
  1. 7.   The Nonnucleoside Reverse Transcriptase Inhibitor MIV-150 in Carrageenan Gel Prevents Rectal Transmission of Simian/Human Immunodeficiency Virus Infection in Macaques
  2. Singer, R.; Derby, N.; Rodriguez, A.; Kizima, L.; Kenney, J.; Aravantinou, M.; Chudolij, A.; Gettie, A.; Blanchard, J.; Lifson, J. D.; Piatak, M.; Fernandez-Romero, J. A.; Zydowsky, T. M.; Robbiani, M.
  3. Journal of Virology. 2011, Jun; 85(11): 5504-5512.
  1. 8.   Anti-HIV microbicide development: targeting the virus is the key
  2. O'Keefe, B. R.
  3. Future Virology. 2011, May; 6(5): 553-556.
  1. 9.   An Antiretroviral/Zinc Combination Gel Provides 24 Hours of Complete Protection against Vaginal SHIV Infection in Macaques
  2. Kenney, J.; Aravantinou, M.; Singer, R.; Hsu, M.; Rodriguez, A.; Kizima, L.; Abraham, C. J.; Menon, R.; Seidor, S.; Chudolij, A.; Gettie, A.; Blanchard, J.; Lifson, J. D.; Piatak, M.; Fernandez-Romero, J. A.; Zydowsky, T. M.; Robbiani, M.
  3. Plos One. 2011, Jan; 6(1): 10.
  1. 10.   Behavioral/Lifestyle and Immunologic Factors Associated with HPV Infection among Women Older Than 45 Years
  2. Gonzalez, P.; Hildesheim, A.; Rodriguez, A. C.; Schiffman, M.; Porras, C.; Wacholder, S.; Pineres, A. G.; Pinto, L. A.; Burk, R. D.; Herrero, R.
  3. Cancer Epidemiology Biomarkers & Prevention. 2010, Dec; 19(12): 3044-3054.
  1. 11.   Determinants of Protection among HIV-Exposed Seronegative Persons: An Overview
  2. Lederman, M. M.; Alter, G.; Daskalakis, D. C.; Rodriguez, B.; Sieg, S. F.; Hardy, G.; Cho, M.; Anthony, D.; Harding, C.; Weinberg, A.; Silverman, R. H.; Douek, D. C.; Margolis, L.; Goldstein, D. B.; Carrington, M.; Goedert, J. J.
  3. Journal of Infectious Diseases. 2010, Nov; 202: S333-S338.
  1. 12.   Mannose-rich glycosylation patterns on HIV-1 subtype C gp120 and sensitivity to the lectins, Griffithsin, Cyanovirin-N and Scytovirin
  2. Alexandre, K. B.; Gray, E. S.; Lambson, B. E.; Moore, P. L.; Choge, I. A.; Mlisana, K.; Karim, S. S. A.; McMahon, J.; O'Keefe, B.; Chikwamba, R.; Morris, L.
  3. Virology. 2010, Jun; 402(1): 187-196.
  1. 13.   Systemic Administration of Antiretrovirals Prior to Exposure Prevents Rectal and Intravenous HIV-1 Transmission in Humanized BLT Mice
  2. Denton, P. W.; Krisko, J. F.; Powell, D. A.; Mathias, M.; Kwak, Y. T.; Martinez-Torres, F.; Zou, W.; Payne, D. A.; Estes, J. D.; Garcia, J. V.
  3. Plos One. 2010, Jan; 5(1): 11.
  1. 14.   Glycerol monolaurate prevents mucosal SIV transmission
  2. Li, Q. S.; Estes, J. D.; Schlievert, P. M.; Duan, L. J.; Brosnahan, A. J.; Southern, P. J.; Reilly, C. S.; Peterson, M. L.; Schultz-Darken, N.; Brunner, K. G.; Nephew, K. R.; Pambuccian, S.; Lifson, J. D.; Carlis, J. V.; Haase, A. T.
  3. Nature. 2009 458(7241): 1034-U113.
  1. 15.   High Specific Infectivity of Plasma Virus from the Pre-Ramp-Up and Ramp-Up Stages of Acute Simian Immunodeficiency Virus Infection
  2. Ma, Z. M.; Stone, M.; Piatak, M.; Schweighardt, B.; Haigwood, N. L.; Montefiori, D.; Lifson, J. D.; Busch, M. P.; Miller, C. J.
  3. Journal of Virology. 2009 83(7): 3288-3297.
  1. 16.   Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component
  2. O'Keefe, B. R.; Vojdani, F.; Buffa, V.; Shattock, R. J.; Montefiori, D. C.; Bakke, J.; Mirsalis, J.; d'Andrea, A. L.; Hume, S. D.; Bratcher, B.; Saucedo, C. J.; McMahon, J. B.; Pogue, G. P.; Palmer, K. E.
  3. Proceedings of the National Academy of Sciences of the United States of America. 2009 106(15): 6099-6104.
  1. 17.   Griffithsin, a potent HIV entry inhibitor, is an excellent candidate for anti-HIV microbicide
  2. Emau, P.; Tian, B.; O'Keefa, B. R.; Mori, T.; McMahon, J. B.; Palmer, K. E.; Jiang, Y.; Bekele, G.; Tsai, C. C.
  3. Journal of Medical Primatology. 2007, Aug; 36(4-5): 244-253.
  1. 18.   Pathways utilized by dendritic cells for binding, uptake, processing and presentation of antigens derived from HIV-1
  2. Sabado, R. L.; Babcock, E.; Kavanagh, D. G.; Tjomsl, V.; Walker, B. D.; Lifson, J. D.; Bhardwaj, N.; Larsson, M.
  3. European Journal of Immunology. 2007, Jul; 37(7): 1752-1763.
  1. 19.   Genital transmission of HPV in a mouse model is potentiated by nonoxynol-9 and inhibited by carrageenan
  2. Roberts, J. N.; Buck, C. B.; Thompson, C. D.; Kines, R.; Bernardo, M.; Choyke, P. L.; Lowy, D. R.; Schiller, J. T.
  3. Nature Medicine. 2007, Jul; 13(7): 857-861.
  1. 20.   Dendritic-cell interactions with HIV: infection and viral dissemination
  2. Wu, L.; KewalRamani, V. N.
  3. Nature Reviews Immunology. 2006, Nov; 6(11): 859-868.
  1. 21.   Mucosal innate immune factors in the female genital tract are associated with vaginal HIV-1 shedding independent of plasma viral load
  2. Cummins, J. E.; Christensen, L.; Lennox, J. L.; Bush, T. J.; Wu, Z. W.; Malamud, D.; Evans-Strickfaden, T.; Siddig, A.; Caliendo, A. M.; Hart, C. E.; Dezzutti, C. S.
  3. Aids Research and Human Retroviruses. 2006, Aug; 22(8): 788-795.
  1. 22.   Urogenital carcinogenesis in female CD1 mice induced by in utero arsenic exposure is exacerbated by postnatal diethylstilbestrol treatment
  2. Waalkes, M. P.; Liu, J.; Ward, J. M.; Powell, D. A.; Diwan, B. A.
  3. Cancer Research. 2006, FEB 1; 66(3): 1337-1345.
  1. 23.   Effect of CD8(+) lymphocyte depletion on virus containment after simian immunodeficiency virus SIVmac251 challenge of live attenuated SIVmac239 Delta 3-vaccinated rhesus macaques
  2. Schmitz, J. E.; Johnson, R. P.; McClure, H. M.; Manson, K. H.; Wy, M. S.; Kuroda, M. J.; Lifton, M. A.; Khunkhun, R. S.; McEvers, K. J.; Gillis, J.; Piatak, M.; Lifson, J. D.; Grosschupff, G.; Racz, P.; Tenner-Racz, K.; Rieber, E. P.; Kuus-Reichel, K.; Gelman, R. S.; Letvin, N. L.; Montefiori, D. C.; Ruprecht, R. M.; Desrosiers, R. C.; Reimann, K. A.
  3. Journal of Virology. 2005, JUL; 79(13): 8131-8141.
  1. 24.   Retroviral recombination in vivo: Viral replication patterns and genetic structure of simian immunodeficiency virus (SIV) populations in rhesus macaques after simultaneous or sequential intravaginal inoculation with SIVmac239 Delta vpx/Delta vpr and SIVmac239 Delta nef
  2. Kim, E. Y.; Busch, M.; Abel, K.; Fritts, L.; Bustamante, P.; Stanton, J.; Lu, D.; Wu, S.; Glowczwskie, J.; Rourke, T.; Bogdan, D.; Piatak, M.; Lifson, J. D.; Desrosiers, R. C.; Wolinsky, S.; Miller, C. J.
  3. Journal of Virology. 2005, APR; 79(8): 4886-4895.
  1. 25.   Novel strategies in HIV prevention-development of topical microbicides
  2. Beer, B. E.; Cummins, J. E.
  3. Annual Reports in Medicinal Chemistry, Vol 40. 2005; 40 : 277-290.
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