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  1. 1.   TPM, FPKM, or Normalized Counts? A Comparative Study of Quantification Measures for the Analysis of RNA-seq Data from the NCI Patient-Derived Models Repository
  2. Zhao, Yingdong; Li, Ming-Chung; Konaté, Mariam M; Chen,Li; Das,Biswajit; Karlovich,Chris; Williams,Mickey; Evrard,Yvonne; Doroshow, James H; McShane, Lisa M
  3. Journal of translational medicine. 2021, Jun 22; 19(1): 269.
  1. 2.   Advanced genetic engineering to achieve in vivo targeting of adenovirus utilizing camelid single domain antibody
  2. Lee, Myungeun; Lu, Zhi Hong; Shoemaker, Charles B.; Tremblay, Jacqueline M.; St Croix,Brad; Seaman,Steven; Gonzalez-Pastor, Rebeca; Kashentseva, Elena A.; Dmitriev, Igor P.; Curiel, David T.
  3. Journal of Controlled Release : Official Journal of the Controlled Release Society. 2021, Jun 10; 334: 106-113.
  1. 3.   TET2 and DNMT3A mutations and exceptional response to 4'-thio-2'-deoxycytidine in human solid tumor models
  2. Yang, Sherry X; Hollingshead, Melinda; Rubinstein, Larry; Nguyen, Dat; Larenjeira, Angelo B A; Kinders,Robert; Difilippantonio, Michael; Doroshow, James H
  3. Journal of Hematology & Oncology. 2021, May 26; 14(1):
  1. 4.   Proteogenomic insights into the biology and treatment of HPV-negative head and neck squamous cell carcinoma
  2. Huang, Chen; Chen, Lijun; Savage, Sara R.; Eguez, Rodrigo Vargas; Dou, Yongchao; Li, Yize; Leprevost, Felipe da Veiga; Jaehnig, Eric J.; Lei, Jonathan T.; Wen, Bo; Schnaubelt, Michael; Krug, Karsten; Song, Xiaoyu; Cieslik, Marcin; Chang, Hui-Yin; Wyczalkowski, Matthew A.; Li, Kai; Colaprico, Antonio; Li, Qing Kay; Clark, David J.; Hu, Yingwei; Cao, Liwei; Pan, Jianbo; Wang, Yuefan; Cho, Kyung-Cho; Shi, Zhiao; Liao, Yuxing; Jiang, Wen; Anurag, Meenakshi; Ji, Jiayi; Yoo, Seungyeul; Zhou, Daniel Cui; Liang, Wen-Wei; Wendl, Michael; Vats, Pankaj; Carr, Steven A.; Mani, D. R.; Zhang, Zhen; Qian, Jiang; Chen, Xi S.; Pico, Alexander R.; Wang, Pei; Chinnaiyan, Arul M.; Ketchum, Karen A.; Kinsinger, Christopher R.; Robles, Ana; An, Eunkyung; Hiltke, Tara; Mesri, Mehdi; Thiagarajan,Mathangi; Weaver, Alissa M.; Sikora, Andrew G.; Lubinski, Jan; Wierzbicka, Malgorzata; Wiznerowicz, Maciej; Satpathy, Shankha; Gillette, Michael A.; Miles, George; Ellis, Matthew J.; Omenn, Gilbert S.; Rodriguez, Henry; Boja, Emily S.; Dhanasekaran, Saravana M.; Ding, Li; Nesvizhskii, Alexey; El-Naggar, Adel K.; Chan, Daniel W.; Zhang, Hui; Zhang, Bing
  3. Cancer Cell. 2021, Mar 8; 39(3): 361-379.
  1. 5.   Design and Implementation of the Pre-Clinical DICOM Standard in Multi-Cohort Murine Studies
  2. Kalen,Joseph; Clunie, David A.; Liu,Yanling; Tatum, James L.; Jacobs, Paula M.; Kirby,Justin; Freymann,John; Wagner,Ulli; Smith, Kirk E.; Suloway, Christian; Doroshow, James H.
  3. Tomography. 2021, Mar; 7(1): 1-9.
  1. 6.   Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
  2. Woo, Xing Yi; Giordano, Jessica; Srivastava, Anuj; Zhao, Zi-Ming; Lloyd, Michael W.; de Bruijn, Roebi; Suh, Yun-Suhk; Patidar, Rajesh; Chen,Li; Scherer, Sandra; Bailey, Matthew H.; Yang, Chieh-Hsiang; Cortes-Sanchez, Emilio; Xi, Yuanxin; Wang, Jing; Wickramasinghe, Jayamanna; Kossenkov, Andrew V.; Rebecca, Vito W.; Sun, Hua; Mashl, R. Jay; Davies, Sherri R.; Jeon, Ryan; Frech, Christian; Randjelovic, Jelena; Rosains, Jacqueline; Galimi, Francesco; Bertotti, Andrea; Lafferty, Adam; O'Farrell, Alice C.; Modave, Elodie; Lambrechts, Diether; ter Brugge, Petra; Serra, Violeta; Marangoni, Elisabetta; El Botty, Rania; Kim, Hyunsoo; Kim, Jong-Il; Yang, Han-Kwang; Lee, Charles; Dean, Dennis A.; Davis-Dusenbery, Brandi; Evrard, Yvonne A.; Doroshow, James H.; Welm, Alana L.; Welm, Bryan E.; Lewis, Michael T.; Fang, Bingliang; Roth, Jack A.; Meric-Bernstam, Funda; Herlyn, Meenhard; Davies, Michael A.; Ding, Li; Li, Shunqiang; Govindan, Ramaswamy; Isella, Claudio; Moscow, Jeffrey A.; Trusolino, Livio; Byrne, Annette T.; Jonkers, Jos; Bult, Carol J.; Medico, Enzo; Chuang, Jeffrey H.
  3. Nature Genetics. 2021, Jan; 53(1): 86-99.
  1. 7.   Single cell-derived primary rectal carcinoma cell lines reflect intratumor heterogeneity associated with treatment response
  2. Braun, Rüdiger; Anthuber, Lena; Hirsch, Daniela; Wangsa, Darawalee; Lack,Justin; McNeil, Nicole E; Heselmeyer-Haddad, Kerstin; Torres, Irianna; Wangsa, Danny; Brown, Markus A; Tubbs, Anthony; Auslander, Noam; Gertz, E Michael; Brauer, Philip R; Cam,Maggie; Sackett, Dan; Habermann, Jens K; Nussenzweig, Andre; Ruppin, Eytan; Zhang, Zhongqiu; Rosenberg, Daniel W; Ried, Thomas
  3. Clinical cancer research : an official journal of the American Association for Cancer Research. 2020, JUL; 26(13): 3468-3480.
  1. 8.   Systematic Establishment of Robustness and Standards in Patient-Derived Xenograft Experiments and Analysis
  2. Evrard,Yvonne; Srivastava, Anuj; Randjelovic, Jelena; Consortium, Nci PDXNet; Doroshow, James H; Dean, Dennis A; Morris, Jeffrey S; Chuang, Jeffrey H
  3. Cancer research. 2020, JUN 1; 80(11): 2286-2297.
  1. 9.   Eribulin Regresses a Cisplatinum-resistant Rare-type Triple-negative Matrix-producing Breast Carcinoma Patient-derived Orthotopic Xenograft Mouse Model
  2. Yamamoto, Jun; Murata, Takuya; Sugisawa, Norihiko; Higuchi, Takashi; Tashiro, Yoshihiko; Nishino, Hiroto; Inubushi, Sachiko; Sun, Y U; Lim, Hyein; Miyake, Kentaro; Shimoya, Koichiro; Nomura, Tsunehisa; Kurebayashi, Junichi; Tanino, Hirokazu; Hozumi, Chihiro; Bouvet, Michael; Singh,Shree Ram; Endo, Itaru; Hoffman, Robert M
  3. Anticancer research. 2020, May; 40(5): 2475-2479.
  1. 10.   A Single Low Dose of Eribulin Regressed a Highly Aggressive Triple-negative Breast Cancer in a Patient-derived Orthotopic Xenograft Model
  2. Lim, Hye In; Yamamoto, Jun; Inubushi, Sachiko; Nishino, Hiroto; Tashiro, Yoshihiko; Sugisawa, Norihiko; Han, Quinhong; Sun, Y U; Choi, Hee Jun; Nam, Seok Jin; Kim, Moon Bo; Lee, Ji Sun; Hozumi, Chihiro; Bouvet, Michael; Singh,Shree Ram; Hoffman, Robert M
  3. Anticancer research. 2020, May; 40(5): 2481-2485.
  1. 11.   A Triple-negative Matrix-producing Breast Carcinoma Patient-derived Orthotopic Xenograft (PDOX) Mouse Model Is Sensitive to Bevacizumab and Vinorelbine, Regressed by Eribulin and Resistant to Olaparib
  2. Yamamoto, Jun; Murata, Takuya; Tashiro, Yoshihiko; Higuchi, Takashi; Sugisawa, Norihiko; Nishino, Hiroto; Inubushi, Sachiko; Sun, Y U; Lim, Hyein; Miyake, Kentaro; Hongo, Atsushi; Nomura, Tsunehisa; Saitoh, Wataru; Moriya, Takuya; Tanino, Hirokazu; Hozumi, Chihiro; Bouvet, Michael; Singh,Shree Ram; Endo, Itaru; Hoffman, Robert M
  3. Anticancer research. 2020, May; 40(5): 2509-2514.
  1. 12.   Eribulin Regresses a Doxorubicin-resistant Dedifferentiated Liposarcoma in a Patient-derived Orthotopic Xenograft Mouse Model
  2. Igarashi, Kentaro; Kawaguchi, Kei; Kiyuna, Tasuku; Miyake, Kentaro; Higuchi, Takashi; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Singh,Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M
  3. Cancer genomics & proteomics. 2020, Jul-Aug; 17(4): 351-358.
  1. 13.   A spontaneously metastatic model of bladder cancer: imaging characterization
  2. Tatum, James L; Kalen,Joseph; Jacobs, Paula M; Ileva,Lilia; Riffle,Lisa; Hollingshead,Melinda; Doroshow, James H
  3. Journal of translational medicine. 2019, Dec 19; 17(1): 425.
  1. 14.   Oral recombinant methioninase combined with oxaliplatinum and 5-fluorouracil regressed a colon cancer growing on the peritoneal surface in a patient-derived orthotopic xenograft mouse model
  2. Park, Jun Ho; Han, Qinghong; Zhao, Ming; Tan, Yuying; Higuchi, Takashi; Yoon, Sang Nam; Sugisawa, Norihiko; Yamamoto, Jun; Bouvet, Michael; Clary, Bryan; Singh,Shree Ram; Hoffman, Robert M
  3. Tissue & cell. 2019, Dec; 61: 109-114.
  1. 15.   The combination of oral-recombinant methioninase and azacitidine arrests a chemotherapy-resistant osteosarcoma patient-derived orthotopic xenograft mouse model
  2. Higuchi, Takashi; Sugisawa, Norihiko; Yamamoto, Jun; Oshiro, Hiromichi; Han, Qinghong; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Igarashi, Kentaro; Tan, Yuying; Kuchipudi, Shreya; Bouvet, Michael; Singh,Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M
  3. Cancer chemotherapy and pharmacology. 2019, Nov 08;
  1. 16.   Efficacy of oral recombinant methioninase combined with oxaliplatinum and 5-fluorouracil on primary colon cancer in a patient-derived orthotopic xenograft mouse model
  2. Park, Jun Ho; Zhao, Ming; Han, Qinghong; Sun, Yu; Higuchi, Takashi; Sugisawa, Norihiko; Yamamoto, Jun; Singh,Shree Ram; Clary, Bryan; Bouvet, Michael; Hoffman, Robert M
  3. Biochemical and biophysical research communications. 2019, Oct 15; 518(2): 306-310.
  1. 17.   Pioglitazone, an agonist of PPAR?, reverses doxorubicin-resistance in an osteosarcoma patient-derived orthotopic xenograft model by downregulating P-glycoprotein expression
  2. Higuchi, Takashi; Sugisawa, Norihiko; Miyake, Kentaro; Oshiro, Hiromichi; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Igarashi, Kentaro; Kline,Zoey; Bouvet, Michael; Singh,Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M
  3. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2019, Oct; 118: 109356.
  1. 18.   Oral Recombinant Methioninase Overcomes Colorectal-cancer Liver Metastasis Resistance to the Combination of 5-Fluorouracil and Oxaliplatinum in a Patient-derived Orthotopic Xenograft Mouse Model
  2. Oshiro, Hiromichi; Tome, Yasunori; Kiyuna, Tasuku; Yoon, Sang Nam; Lwin, Thinzar M; Han, Qinghong; Tan, Yuying; Miyake, Kentaro; Higuchi, Takashi; Sugisawa, Norihiko; Katsuya, Yuki; Park, Jun Ho; Zang, Zhiying; Razmjooei, Sahar; Bouvet, Michael; Clary, Bryan; Singh,Shree Ram; Kanaya, Fuminori; Nishida, Kotaro; Hoffman, Robert M
  3. Anticancer research. 2019, Sep; 39(9): 4667-4671.
  1. 19.   Eribulin Suppressed Cisplatinum- and Doxorubicin-resistant Recurrent Lung Metastatic Osteosarcoma in a Patient-derived Orthotopic Xenograft Mouse Model
  2. Kiyuna, Tasuku; Tome, Yasunori; Miyake, Kentaro; Murakami, Takashi; Oshiro, Hiromichi; Igarashi, Kentaro; Kawaguchi, Kei; Hsu, John; Singh, Manish; Li, Yunfeng; Nelson, Scott; Bouvet, Michael; Singh,Shree Ram; Kanaya, Fuminori; Hoffman, Robert M
  3. Anticancer research. 2019, Sep; 39(9): 4775-4779.
  1. 20.   The combination of gemcitabine and docetaxel arrests a doxorubicin-resistant dedifferentiated liposarcoma in a patient-derived orthotopic xenograft model
  2. Miyake, Kentaro; Higuchi, Takashi; Oshiro, Hiromichi; Zhang, Zhiying; Sugisawa, Norihiko; Park, Jun Ho; Razmjooei, Sahar; Katsuya, Yuki; Barangi, Maryam; Li, Yunfeng; Nelson, Scott D; Murakami, Takashi; Homma, Yuki; Hiroshima, Yukihiko; Matsuyama, Ryusei; Bouvet, Michael; Chawla, Sant P; Singh,Shree Ram; Endo, Itaru; Hoffman, Robert M
  3. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2019, SEP; 117: 109093.
  1. 21.   A pharmacogenomic analysis using L1000CDS2 identifies BX-795 as a potential anticancer drug for primary pancreatic ductal adenocarcinoma cells
  2. Choi, Eun A; Choi, Yeon Sook; Lee, Eun Ji; Singh,Shree Ram; Kim, Song Cheol; Chang, Suhwan
  3. Cancer letters. 2019, Aug 09; 465: 82-93.
  1. 22.   Tumor-sealing Surgical Orthotopic Implantation of Human Colon Cancer in Nude Mice Induces Clinically-relevant Metastases Without Early Peritoneal Carcinomatosis
  2. Yoon, Sang Nam; Park, Jun Ho; Lwin, Thinzar M; Miyake, Kentaro; Singh,Shree Ram; Hoffman, Robert M; Bouvet, Michael
  3. Anticancer research. 2019, Aug; 39(8): 4065-4071.
  1. 23.   Peritoneal Metastases in a Patient-derived Orthotopic Xenograft (PDOX) Model of Colon Cancer Imaged Non-invasively via Red Fluorescent Protein Labeled Stromal Cells
  2. Park, Jun Ho; Zhao, Ming; Oshiro, Hiromichi; Miyake, Kentaro; Higuchi, Takashi; Reynoso, Jose; Razmjooei, Sahar; Bouvet, Michael; Clary, Bryan; Zhang, Zhiying; Sugisawa, Norihiko; Yamamoto, Jun; Singh,Shree Ram; Hoffman, Robert M
  3. Anticancer research. 2019, Jul; 39(7): 3463-3467.
  1. 24.   Pazopanib regresses a doxorubicin-resistant synovial sarcoma in a patient-derived orthotopic xenograft mouse model
  2. Igarashi, Kentaro; Kawaguchi, Kei; Kiyuna, Tasuku; Miyake, Kentaro; Miyake, Masuyo; Nelson, Scott D; Russell, Tara A; Dry, Sarah M; Li, Yunfeng; Yamamoto, Norio; Hayashi, Katsuhiro; Kimura, Hiroaki; Miwa, Shinji; Higuchi, Takashi; Singh,Shree Ram; Tsuchiya, Hiroyuki; Hoffman, Robert M
  3. Tissue & cell. 2019, Jun; 58: 107-111.
  1. 25.   Temozolomide targets and arrests a doxorubicin-resistant follicular dendritic-cell sarcoma patient-derived orthotopic xenograft mouse model
  2. Oshiro, Hiromichi; Tome, Yasunori; Kiyuna, Tasuku; Miyake, Kentaro; Kawaguchi, Kei; Higuchi, Takashi; Miyake, Masuyo; Zang, Zhiying; Razmjooei, Sahar; Barangi, Maryam; Wangsiricharoen, Sintawat; Nelson, Scott D; Li, Yunfeng; Bouvet, Michael; Singh,Shree Ram; Kanaya, Fuminori; Hoffman, Robert M
  3. Tissue & cell. 2019, Jun; 58: 17-23.
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