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  1. 1.   Use of Drosophila deoxynucleoside kinase to study mechanism of toxicity and mutagenicity of deoxycytidine analogs in Escherichia coli
  2. Betham, B.; Shalhout, S.; Marquez, V. E.; Bhagwat, A. S.
  3. DNA Repair. 2010, Feb; 9(2): 153-160.
  1. 2.   Synthesis and Hybridization Properties of Modified Oligodeoxynucleotides Carrying Non-Natural Bases
  2. Avino, A.; Perez-Rentero, S.; Garibotti, A. V.; Siddiqui, M. A.; Marquez, V. E.; Eritja, R.
  3. Chemistry & Biodiversity. 2009 6(2): 117-126.
  1. 3.   Activation of p16 Gene Silenced by DNA Methylation in Cancer Cells by Phosphoramidate Derivatives of 2 '-Deoxyzebularine
  2. Yoo, C. B.; Valente, R.; Congiatu, C.; Gavazza, F.; Angel, A.; Siddiqui, M. A.; Jones, P. A.; McGuigan, C.; Marquez, V. E.
  3. Journal of Medicinal Chemistry. 2008 51(23): 7593-7601.
  1. 4.   The novel DNA methylation inhibitor zebularine is effective against the development of murine T-cell lymphoma
  2. Herranz, M.; Martin-Caballero, J.; Fraga, M. F.; Ruiz-Cabello, J.; Flores, J. M.; Desco, M.; Marquez, V.; Esteller, M.
  3. Blood. 2006, FEB 1; 107(3): 1174-1177.
  1. 5.   Metabolic activation of zebularine, a novel DNA methylation inhibitor, in human bladder carcinoma cells
  2. Ben-Kasus, T.; Ben-Zvi, Z.; Marquez, V. E.; Kelley, J. A.; Agbaria, R.
  3. Biochemical Pharmacology. 2005, JUL 1; 70(1): 121-133.
  1. 6.   Enhancement of in vitro and in vivo tumor cell radiosensitivity by the DNA methylation inhibitor zebularine
  2. Dote, H.; Cerna, D.; Burgan, W. E.; Carter, D. J.; Cerra, M. A.; Hollingshead, M. G.; Camphausen, K.; Tofilon, P. J.
  3. Clinical Cancer Research. 2005, JUN 15; 11(12): 4571-4579.
  1. 7.   Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation
  2. Hodge, D. R.; Peng, B.; Cherry, J. C.; Hurt, E. M.; Fox, S. D.; Kelley, J. A.; Munroe, D. J.; Farrar, W. L.
  3. Cancer Research. 2005, JUN 1; 65(11): 4673-4682.
  1. 8.   Enhancement of antineoplastic action of 5-aza-2'-deoxycytidine by zebularine on L1210 leukemia
  2. Lemaire, M.; Momparler, L. F.; Bernstein, M. L.; Marquez, V. E.; Momparler, R. L.
  3. Anti-Cancer Drugs. 2005, MAR; 16(3): 301-308.
  1. 9.   Epigenetic silencing of the human nucleotide excision repair gene, hHR23B, in interleukin-6-responsive multiple myeloma KAS-6/1 cells
  2. Pengt, B.; Hodge, D. R.; Thomas, S. B.; Cherry, J. M.; Munroe, D. J.; Pompeia, C.; Xiao, W. H.; Farrar, W. L.
  3. Journal of Biological Chemistry. 2005, FEB 11; 280(6): 4182-4187.
  1. 10.   Zebularine: A unique molecule for an epigenetically based strategy in cancer chemotherapy
  2. Marquez, V. E.; Kelley, J. A.; Agbaria, R.; Ben-Kasus, T.; Cheng, J. C.; Yoo, C. B.; Jones, P. A.
  3. Therapeutic Oligonucleotides: Transcriptional and Translational Strategies for Silencing Gene Expression. 2005; 1058 : 246-254.
  1. 11.   Zebularine: A unique molecule for an epigenetically based strategy in cancer chemotherapy. The magic of its chemistry and biology
  2. Marquez, V. E.; Barchi, J. J.; Kelley, J. A.; Rao, K. V. R.; Agbaria, R.; Ben-Kasus, T.; Cheng, J. C.; Yoo, C. B.; Jones, P. A.
  3. Nucleosides Nucleotides & Nucleic Acids. 2005 24(5-7, Sp. Iss.): 305-318.
  1. 12.   Zebularine induces and sustains DNA cytosine demethylation in human cancer cells
  2. Jones, P. A.; Cheng, J. C.; Yoo, C.; Liang, G. N.; Marquez, V. E.
  3. Abstracts of Papers of the American Chemical Society. 2004, AUG 22; 228(Part 1): 163-MEDI, Abstract U937-163-MEDI, Abstract U937.
  1. 13.   Preferential response of cancer cells to zebularine
  2. Cheng, J. C.; Yoo, C. B.; Weisenberger, D. J.; Chuang, J.; Wozniak, C.; Liang, G. N.; Marquez, V. E.; Greer, S.; Orntoft, T. F.; Thykjaer, T.; Jones, P. A.
  3. Cancer Cell. 2004, AUG; 6(2): 151-158.
  1. 14.   Synthesis, stability, and protonation studies of a self- complementary dodecamer containing the modified nucleoside 2 '- deoxyzebularine
  2. Vives, M.; Eritja, R.; Tauler, R.; Marquez, V. E.; Gargallo, R.
  3. Biopolymers. 2004 73(1): 27-43.
  1. 15.   Microarray analysis of epigenetic silencing of gene expression in the KAS-6/1 multiple myeloma cell line
  2. Pompeia, C.; Hodge, D. R.; Plass, C.; Wu, Y. Z.; Marquez, V. E.; Kelley, J. A.; Farrar, W. L.
  3. Cancer Research. 2004 64(10): 3465-3473.
  1. 16.   Potent inhibition of HhaI DNA methylase by the aglycon of 2-(1H)-pyrimidinone riboside (Zebularine) at the G(C)under-barGC recognition domain
  2. Marquez, V. E.; Eritja, R.; Kelley, J. A.; Vanbemmel, D.; Christman, J.
  3. THERAPEUTIC OLIGONUCLEOTIDES. 2003; 1002 : 154-164.
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