Selective Bibliography of Dr. Dennis M. Klinman
Cancer and Inflammation Program, NCI

“Immunomodulatory Oligonucleotides: Impact on Inflammation and Disease”
Wednesday, February 13, 2019
 

  1. Bayik D, Tross D, Haile LA, Verthelyi D, Klinman DM
    Regulation of the maturation of human monocytes into immunosuppressive macrophages
    Blood Advances 1 (26):2510-2519 Dec 12 2017

  2. Zhao BG, Vasilakos JP, Tross D, Smirnov D, Klinman DM
    Combination therapy targeting toll like receptors 7, 8 and 9 eliminates large established tumors
    Journal for Immunotherapy of Cancer 2:12 2014

  3. Shirota Y, Shirota H, Klinman DM
    Intratumoral injection of CpG oligonucleotides induces the differentiation and reduces the immunosuppressive activity of myeloid-derived suppressor cells
    Journal of Immunology (Baltimore, Md.: 1950) 188 (4):1592-9 Feb 15 2012

  4. Shirota H, Klinman DM
    CpG-conjugated apoptotic tumor cells elicit potent tumor-specific immunity
    Cancer Immunology, Immunotherapy: CII 60 (5):659-69 May 2011

  5. Sato T, Yamamoto M, Shimosato T, Klinman DM
    Accelerated wound healing mediated by activation of Toll-like receptor 9
    Wound Repair and Regeneration: Official Publication of the Wound Healing Society & the European Tissue Repair Society 18 (6):586-93 Nov-Dec 2010

  6. Verthelyi D, Kenney RT, Seder RA, Gam AA, Friedag B, Klinman DM
    CpG oligodeoxynucleotides as vaccine adjuvants in primates
    Journal of Immunology (Baltimore, Md.: 1950) 168 (4):1659-63 Feb 15 2002

  7. Takeshita F, Leifer CA, Gursel I, Ishii KJ, Takeshita S, Gursel M, Klinman DM
    Cutting edge: Role of Toll-like receptor 9 in CpG DNA-induced activation of human cells
    Journal of Immunology (Baltimore, Md.: 1950) 167 (7):3555-8 Oct 1 2001

  8. Verthelyi D, Ishii KJ, Gursel M, Takeshita F, Klinman DM
    Human peripheral blood cells differentially recognize and respond to two distinct CPG motifs
    Journal of immunology (Baltimore, Md. : 1950) 166 (4):2372-7 Feb 15 2001

  9. Sur S, Wild JS, Choudhury BK, Sur N, Alam R, Klinman DM
    Long term prevention of allergic lung inflammation in a mouse model of asthma by CpG oligodeoxynucleotides
    Journal of Immunology (Baltimore, Md.: 1950) 162 (10):6284-93 May 15 1999

  10. Elkins KL, Rhinehart-Jones TR, Stibitz S, Conover JS, Klinman DM
    Bacterial DNA containing CpG motifs stimulates lymphocyte-dependent protection of mice against lethal infection with intracellular bacteria
    Journal of Immunology (Baltimore, Md.: 1950) 162 (4):2291-8 Feb 15 1999

  11. Klinman DM, Yi AK, Beaucage SL, Conover J, Krieg AM
    CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma
    Proceedings of the National Academy of Sciences of the United States of America 93 (7):2879-83 Apr 2 1996

  12. Krieg AM, Yi AK, Matson S, Waldschmidt TJ, Bishop GA, Teasdale R, Koretzky GA, Klinman DM
    CpG motifs in bacterial DNA trigger direct B-cell activation
    Nature 374 (6522):546-9 Apr 6 1995

     

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